Nature Medicine
Journal Impact IF - Analysis · Trend · Prediction · Ranking


New

Journal Impact IF

2019-2020

36.13

17.9%

Journal Impact IF Trend

Related Journals

Popular Journals

Nature Medicine

The 2019-2020 Journal Impact IF of Nature Medicine is 36.13, which is just updated in 2020.

Nature Medicine Impact Factor
Highest IF
36.13
Highest Journal Impact IF

The highest Journal Impact IF of Nature Medicine is 36.13.

Lowest IF
22.462
Lowest Journal Impact IF

The lowest Journal Impact IF of Nature Medicine is 22.462.

Total Growth Rate
60.8%
IF Total Growth Rate

The total growth rate of Nature Medicine IF is 60.8%.

Annual Growth Rate
6.8%
IF Annual Growth Rate

The annual growth rate of Nature Medicine IF is 6.8%.

Journal Impact IF Ranking

Subcategory Quartile Rank Percentile
General Biochemistry,Genetics and Molecular Biology Q1 2/197

General Biochemistry,Genetics and Molecular Biology 99%

Journal Impact IF Ranking

· In the General Biochemistry,Genetics and Molecular Biology research field, the Quartile of Nature Medicine is Q1. Nature Medicine has been ranked #2 over 197 related journals in the General Biochemistry,Genetics and Molecular Biology research category. The ranking percentile of Nature Medicine is around 99% in the field of General Biochemistry,Genetics and Molecular Biology.

Nature Medicine Impact Factor 2020-2021 Prediction

Nature Medicine Impact Factor Predition System

Nature Medicine Impact Factor Prediction System is now online. You can start share your valuable insights with the community.

Predict Check All Preditions
Total Publications
11677
Total Citations
1988391

Annual Publication Volume

Annual Citation Record

International Collaboration Trend

Cited Documents Trend

Journal Impact IF History

Year Journal Impact IF
Year Journal Impact IF
2019-2020 36.13
2018-2019 30.641
2017-2018 32.621
2016-2017 29.886
2015-2016 30.357
2014-2015 28.223
2013-2014 28.054
2012-2013 24.302
2011-2012 22.462
Journal Impact IF History

· The 2019-2020 Journal Impact IF of Nature Medicine is 36.13
· The 2018-2019 Journal Impact IF of Nature Medicine is 30.641
· The 2017-2018 Journal Impact IF of Nature Medicine is 32.621
· The 2016-2017 Journal Impact IF of Nature Medicine is 29.886
· The 2015-2016 Journal Impact IF of Nature Medicine is 30.357
· The 2014-2015 Journal Impact IF of Nature Medicine is 28.223
· The 2013-2014 Journal Impact IF of Nature Medicine is 28.054
· The 2012-2013 Journal Impact IF of Nature Medicine is 24.302
· The 2011-2012 Journal Impact IF of Nature Medicine is 22.462

Publications Cites Dataset

Year Publications Citations
Year Publications Citations
1994 1 41
1995 534 999
1996 567 4710
1997 500 12080
1998 555 19889
1999 539 29406
2000 511 37416
2001 453 44532
2002 434 51108
2003 454 57471
2004 490 63225
2005 440 70253
2006 436 77427
2007 394 80018
2008 372 85466
2009 432 86613
2010 498 92113
2011 586 98970
2012 553 108272
2013 471 116429
2014 386 115034
2015 276 113943
2016 272 110969
2017 255 115565
2018 334 102162
2019 411 117158
2020 485 164261
2021 38 12861
Publications Cites Dataset

· The Nature Medicine has published 1 reports and received 41 citations in 1994.
· The Nature Medicine has published 534 reports and received 999 citations in 1995.
· The Nature Medicine has published 567 reports and received 4710 citations in 1996.
· The Nature Medicine has published 500 reports and received 12080 citations in 1997.
· The Nature Medicine has published 555 reports and received 19889 citations in 1998.
· The Nature Medicine has published 539 reports and received 29406 citations in 1999.
· The Nature Medicine has published 511 reports and received 37416 citations in 2000.
· The Nature Medicine has published 453 reports and received 44532 citations in 2001.
· The Nature Medicine has published 434 reports and received 51108 citations in 2002.
· The Nature Medicine has published 454 reports and received 57471 citations in 2003.
· The Nature Medicine has published 490 reports and received 63225 citations in 2004.
· The Nature Medicine has published 440 reports and received 70253 citations in 2005.
· The Nature Medicine has published 436 reports and received 77427 citations in 2006.
· The Nature Medicine has published 394 reports and received 80018 citations in 2007.
· The Nature Medicine has published 372 reports and received 85466 citations in 2008.
· The Nature Medicine has published 432 reports and received 86613 citations in 2009.
· The Nature Medicine has published 498 reports and received 92113 citations in 2010.
· The Nature Medicine has published 586 reports and received 98970 citations in 2011.
· The Nature Medicine has published 553 reports and received 108272 citations in 2012.
· The Nature Medicine has published 471 reports and received 116429 citations in 2013.
· The Nature Medicine has published 386 reports and received 115034 citations in 2014.
· The Nature Medicine has published 276 reports and received 113943 citations in 2015.
· The Nature Medicine has published 272 reports and received 110969 citations in 2016.
· The Nature Medicine has published 255 reports and received 115565 citations in 2017.
· The Nature Medicine has published 334 reports and received 102162 citations in 2018.
· The Nature Medicine has published 411 reports and received 117158 citations in 2019.
· The Nature Medicine has published 485 reports and received 164261 citations in 2020.
· The Nature Medicine has published 38 reports and received 12861 citations in 2021.
· The total publications of Nature Medicine is 11677.
· The total citations of Nature Medicine is 1988391.

What is Impact Factor?

The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly average number of citations of articles published in the last two years in a given journal. It is frequently used as a proxy for the relative importance of a journal within its field; journals with higher impact factor values are often deemed to be more important, or carry more intrinsic prestige in their respective fields, than those with lower values.

Nature Medicine | Academic Accelerator - About the Impact Factor

Impact factor is commonly used to evaluate the relative importance of a journal within its field and to measure the frequency with which the “average article” in a journal has been cited in a particular time period. Journal which publishes more review articles will get highest IFs. Journals with higher IFs believed to be more important than those with lower ones. According to Eugene Garfield “impact simply reflects the ability of the journals and editors to attract the best paper available.” Journal which publishes more review articles will get maximum IFs. The Impact Factor of an academic journal is a scientometric Metric that reflects the yearly average number of citations that recent articles published in a given journal received. It is frequently used as a Metric for the relative importance of a journal within its field; journals with higher Impact Factor are often deemed to be more important than those with lower ones. The Nature Medicine Impact Factor IF measures the average number of citations received in a particular year (2020) by papers published in the Nature Medicine during the two preceding years (2018-2019). Note that 2020 Impact Factor are reported in 2021; they cannot be calculated until all of the 2020 publications have been processed by the indexing agency. New journals, which are indexed from their first published issue, will receive an impact factor after two years of indexing; in this case, the citations to the year prior to Volume 1, and the number of articles published in the year prior to Volume 1, are known zero values. Journals that are indexed starting with a volume other than the first volume will not get an impact factor until they have been indexed for three years. Occasionally, Journal Citation Reports assigns an impact factor to new journals with less than two years of indexing, based on partial citation data. The calculation always uses two complete and known years of item counts, but for new titles one of the known counts is zero. Annuals and other irregular publications sometimes publish no items in a particular year, affecting the count. The impact factor relates to a specific time period; it is possible to calculate it for any desired period. In addition to the 2-year Impact Factor, the 3-year Impact Factor, 4-year Impact Factor, 5-year Impact Factor, Real-Time Impact Factor can provide further insights and factors into the impact of Nature Medicine.

History

The impact factor was devised by Eugene Garfield, the founder of the Institute for Scientific Information (ISI). Impact factors are calculated yearly starting from 1975 for journals listed in the Journal Citation Reports (JCR). ISI was acquired by Thomson Scientific & Healthcare in 1992, and became known as Thomson ISI. In 2018, Thomson ISI was sold to Onex Corporation and Baring Private Equity Asia. They founded a new corporation, Clarivate, which is now the publisher of the JCR.

Use

The impact factor is used to compare different journals within a certain field. The Web of Science indexes more than 11,500 science and social science journals. Journal impact factors are often used to evaluate the merit of individual articles and individual researchers. This use of impact factors was summarised by Hoeffel:

Impact Factor is not a perfect tool to measure the quality of articles but there is nothing better and it has the advantage of already being in existence and is, therefore, a good technique for scientific evaluation. Experience has shown that in each specialty the best journals are those in which it is most difficult to have an article accepted, and these are the journals that have a high impact factor. Most of these journals existed long before the impact factor was devised. The use of impact factor as a measure of quality is widespread because it fits well with the opinion we have in each field of the best journals in our specialty....In conclusion, prestigious journals publish papers of high level. Therefore, their impact factor is high, and not the contrary.

Eugene Garfield

In brief, Impact factors may be used by:
  • Authors to decide where to submit an article for publication.
  • Libraries to make collection development decisions
  • Academic departments to assess academic productivity
  • Academic departments to make decisions on promotion and tenure.
As impact factors are a journal-level metric, rather than an article- or individual-level metric, this use is controversial. Garfield agrees with Hoeffel,but warns about the "misuse in evaluating individuals" because there is "a wide variation [of citations] from article to article within a single journal". Other things to consider about Impact Factors:
  • Many journals do not have an impact factor.
  • The impact factor cannot assess the quality of individual articles. Even if citations were evenly distributed among articles, the impact factor would only measure the interests of other researchers in an article, not its importance and usefulness.
  • Only research articles, technical notes and reviews are “citable” items. Editorials, letters, news items and meeting abstracts are “non-citable items”.
  • Only a small percentage of articles are highly cited and they are found in a small subset of journals. This small proportion accounts for a large percentage of citations.
  • Controversial papers, such as those based on fraudulent data, may be highly cited, distorting the impact factor of a journal.
  • Citation bias may exist. For example, English language resources may be favoured. Authors may cite their own work.
Moreover, informed and careful use of these impact data is essential, and should be based on a thorough understanding of the methodology used to generate impact factors. There are controversial aspects of using impact factors:
  • It is not clear whether the number of times a paper is cited measures its actual quality.
  • Some databases that calculate impact factors fail to incorporate publications including textbooks, handbooks and reference books.
  • Certain disciplines have low numbers of journals and usage. Therefore, one should only compare journals or researchers within the same discipline.
  • Review articles normally are cited more often and therefore can skew results.
  • Self-citing may also skew results.
  • Some resources used to calculate impact factors have inadequate international coverage.
  • Editorial policies can artificially inflate an impact factor.
Impact factors have often been used in advancement and tenure decision-making. Many recognize that this is a coarse tool for such important decisions, and that a multitude of factors should be taken into account in these deliberations. When considering the use of the impact factor (IF), keep these aspects in mind:
  • IF analysis is limited to citations from the journals indexed by the Web of Science/Web of Knowledge. Currently, the Web of Science indexes only 8621 journals across the full breadth of the sciences, and just 3121 in the social sciences.
  • A high IF/citation rate says nothing about the quality -- or even, validity -- of the references being cited. Notorious or even retracted articles often attract a lot of attention, hence a high number of citations. The notority related to the first publication on "cold fusion" is one such example.
  • Journals that publish more "review articles" are often found near the top of the rankings. While not known for publishing new, creative findings, these individual articles tend to be heavily cited.
  • The IF measures the average number of citations to articles in the journal -- given this, a small number of highly-cited articles will skew the figure.
  • It takes several years for new journals to be added to the list of titles indexed by the Web of Science/Web of Knowledge, so these newer titles will be under-represented.
  • It's alleged that journal editors have learned to "game" the system, encouraging authors to cite their works previously published in the same journal.
Comparing Journals Across Disciplines? Not a good idea! Using Impact Factors within a given discipline should only be done with great care, as described above. Using impact factor data to compare journals across disciplines is even more problematic. Here are some of the reasons:
  • Disciplines where older literature is still referenced, such as Chemistry and Mathematics, offer challenges to the methodolgy since older citations (older than two years) are not used to calculate the impact factor for a given journal. (Five-year impact factor analysis, which can be calculated using the Journal Citation Index database, helps smooth out this problem only to some degree.)
  • Different disciplines have different practices regarding tendency to cite larger numbers of references. Higher overall citation rates will bump upward impact factor measurements.
  • Where it's common for large numbers of authors to collaborate on a single paper, such as in Physics, the tendency of authors to cite themselves (and in this case, more authors) will result in increased citation rates.

Pros and Cons of the Impact Factor

Pros:

  • A vetted, established metric for measuring journal impact within a discipline.
  • Designed to eliminate bias based on journal size and frequency.
Cons:
  • Individual articles makes an uneven contribution to overall Impact Factor.
  • Impact Factor does not account for certain things, things like context (postive or negative citaion) and intentionality (self-citation).
  • The metric is proprietary to and bound by the contents of the Thomson Reuters database.
  • Citations, on which the Impact Factor is based, count for less than 1% of an article's overall use.

Criticism

Numerous critiques have been made regarding the use of impact factors. A 2007 study noted that the most fundamental flaw is that impact factors present the mean of data that are not normally distributed, and suggested that it would be more appropriate to present the median of these data. There is also a more general debate on the validity of the impact factor as a measure of journal importance and the effect of policies that editors may adopt to boost their impact factor (perhaps to the detriment of readers and writers). Other criticism focuses on the effect of the impact factor on behavior of scholars, editors and other stakeholders. Others have made more general criticisms, arguing that emphasis on impact factor results from negative influence of neoliberal policies on academia claiming that what is needed is not just replacement of the impact factor with more sophisticated metrics for science publications but also discussion on the social value of research assessment and the growing precariousness of scientific careers in higher education.
Experts stress that there are limitations in using impact factors to evaluate a scholar's work. There are many reasons cited for not relying on impact factor alone to evaluate the output of a particular individual. Among these are the following:

  • A single factor is not sufficient for evaluating an author's work.
  • Journal values are meaningless unless compared within the same discipline. Impact factors vary among disciplines.
  • The impact factor was originally devised to show the impact of a specific journal, not a specific scholar. The quality and impact of the author's work may extend beyond the impact of a particular journal.
According to Jim Testa, a researcher for ThomsonReuters Scientific, the most widespread misuse of the Impact Factor is to evaluate the work of an individual author (instead of a journal). "To say that because a researcher is publishing in a certain journal, he or she is more influential or deserves more credit is not necessarily true. There are many other variables to consider." (interview 6/26/2008 in Thomson Reuters blog entry)

Nature Medicine
Journal Profile

About

Nature Medicine publishes research that addresses the needs and goals of contemporary medicine. Original research ranges from new concepts in human biology and disease pathogenesis to robust preclinical bases for new therapeutic modalities and drug development to all phases of clinical work, as well as innovative technologies aimed at improving human health.Current areas of interest also include, but are not limited to:-Gene and cell therapies-Clinical genomics-Regenerative medicine-High-definition medicine-Effects of the environment in human health-Artificial intelligence in health care-Smart wearable devices-Early disease diagnosis-Microbiome-AgingNature Medicine also publishes Reviews, Perspectives and other content commissioned from leading scientists in their fields to provide expert and contextualized views of the latest research driving the progress of medicine. The News section is editorially independent and provides topical and timely reporting of upcoming trends affecting medicine, researchers and the general audience. Nature Medicine is a monthly peer-reviewed medical journal publishing research articles, reviews, news and commentaries in the biomedical area, including both basic research and early-phase clinical research covering all aspects of medicine. The journal seeks to publish research papers that demonstrate novel insight into disease processes, with direct evidence of the physiological relevance of the results.

Highly Cited Keywords

ISSN
1078-8956
ISSN

The ISSN of Nature Medicine is 1078-8956 . An ISSN is an 8-digit code used to identify newspapers, journals, magazines and periodicals of all kinds and on all media–print and electronic.

ISSN (Online)
1546-170X
ISSN (Online)

The ISSN (Online) of Nature Medicine is 1546-170X . An ISSN is an 8-digit code used to identify newspapers, journals, magazines and periodicals of all kinds and on all media–print and electronic.

Publisher
Nature Publishing Group
Publisher

Nature Medicine is published by Nature Publishing Group .

Publication Frequency
Monthly
Publication Frequency

Nature Medicine publishes reports Monthly .

Coverage
1995 - Present
Coverage

The Publication History of Nature Medicine covers 1995 - Present .

Open Access
NO
Open Access

Nature Medicine is Subscription-based (non-OA) Journal. Publishers own the rights to the articles in their journals. Anyone who wants to read the articles should pay by individual or institution to access the articles. Anyone who wants to use the articles in any way must obtain permission from the publishers.

Publication Fee
Publication Fee

There is no publication fee for submiting manuscript to Nature Medicine. Nature Medicine is Subscription-based (non-OA) Journal. Publishers own the rights to the articles in their journals. Anyone who wants to read the articles should pay by individual or institution to access the articles.

Language
English
Language

The language of Nature Medicine is English .

Country/Region
United Kingdom
Country/Region

The publisher of Nature Medicine is Nature Publishing Group , which locates in United Kingdom .

Selected Articles

Full Title Authors
Full Title Authors
Gut microbiota and intestinal FXR mediate the clinical benefits of metformin Javier Carmona · Javier Carmona
Searching for Alzheimers disease therapies Darren C. Johnson · Cornelius Y. Taabazuing · Marian C. Okondo · Ashley J. Chui · Sahana D. Rao · Fiona Brown · Casie Reed · Elizabeth Peguero · Elisa de Stanchina · Alex Kentsis · Daniel A. Bachovchin · Daniel A. Bachovchin · Daniel A. Bachovchin
Publisher Correction: Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis Neibla Priego · Lucía Zhu · Cátia Monteiro · Manon Mulders · David Wasilewski · Wendy Bindeman · Laura Doglio · Liliana Martínez · Elena Martinez-Saez · Santiago Ramón y Cajal · Diego Megías · Elena Hernández-Encinas · Carmen Blanco-Aparicio · Lola Martínez · Eduardo Zarzuela · Javier Muñoz · Coral Fustero-Torre · Elena Piñeiro-Yáñez · Aurelio Hernández-Laín · Luca Bertero · Valeria Poli · Melchor Sanchez-Martinez · Javier A. Menendez · Riccardo Soffietti · Joaquim Bosch-Barrera · Manuel Valiente · Manuel Valiente
Author Correction: STAT3 labels a subpopulation of reactive astrocytes required for brain metastasis Yong Jie Zhang · Tania F. Gendron · Mark T. W. Ebbert · Aliesha D. O’Raw · Mei Yue · Karen Jansen-West · Xu Zhang · Mercedes Prudencio · Jeannie Chew · Casey Cook · Lillian M. Daughrity · Jimei Tong · Yuping Song · Sarah R. Pickles · Monica Castanedes-Casey · Aishe Kurti · Rosa Rademakers · Bjorn Oskarsson · Dennis W. Dickson · Wenqian Hu · Aaron D. Gitler · John D. Fryer · Leonard Petrucelli · Leonard Petrucelli
Poly(GR) impairs protein translation and stress granule dynamics in C9orf72 -associated frontotemporal dementia and amyotrophic lateral sclerosis Sunad Rangarajan · Nathaniel B. Bone · Anna A. Zmijewska · Shaoning Jiang · Dae Won Park · Dae Won Park · Karen Bernard · Morgan L. Locy · Saranya Ravi · Jessy Deshane · Roslyn B. Mannon · Edward Abraham · Victor M. Darley-Usmar · Victor J. Thannickal · Jaroslaw W. Zmijewski · Jaroslaw W. Zmijewski
Metformin reverses established lung fibrosis in a bleomycin model Hannah Stower · Hannah Stower
A pig model of Huntingtons disease Rob S. Sellar · Rob S. Sellar · Rob S. Sellar · Siddhartha Jaiswal · Benjamin L. Ebert · Benjamin L. Ebert · Benjamin L. Ebert · Benjamin L. Ebert
Predicting progression to AML Hannah Stower · Hannah Stower
DPP8/DPP9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia Hannah Stower · Hannah Stower
F508del-CFTR is not corrected by thymosin α1 Eleonora Trotta · Paul H. Bessette · Stephanie Silveria · Lauren K. Ely · Kevin M. Jude · Duy T. Le · Charles R. Holst · Anthony J. Coyle · Marc Potempa · Lewis L. Lanier · K. Christopher Garcia · Natasha K. Crellin · Isaac J. Rondon · Jeffrey A. Bluestone · Jeffrey A. Bluestone
Green light for data sharing Hannah Stower · Hannah Stower
Understanding genetic disease with electronic medical records Hannah Stower · Hannah Stower
Predicting colon cancer recurrence Scott L. Friedman · Brent A. Neuschwander-Tetri · Mary E. Rinella · Arun J. Sanyal · Arun J. Sanyal
Mechanisms of NAFLD development and therapeutic strategies Trang Thi Mai · Piro Lito · Piro Lito · Piro Lito
A treatment strategy for KRAS-driven tumors Lena Brundin · Liza Bergkvist · Patrik Brundin · Patrik Brundin
Fire prevention in the Parkinsons disease brain Mara Vinci · Anna Burford · Valeria Molinari · Ketty Kessler · Sergey Popov · Matthew Clarke · Kathryn R. Taylor · Helen N. Pemberton · Christopher J. Lord · Alice Gutteridge · Tim Forshew · Diana Carvalho · Lynley V. Marshall · Elizabeth Y. Qin · Wendy J. Ingram · Andrew S. Moore · Ho Keung Ng · Saoussen Trabelsi · Dorra H’mida-Ben Brahim · Natacha Entz-Werle · Stergios Zacharoulis · Stergios Zacharoulis · Sucheta Vaidya · Henry Mandeville · Leslie R. Bridges · Andrew J. Martin · Safa Al-Sarraj · Christopher Chandler · Mariona Suñol · Jaume Mora · Carmen de Torres · Ofelia Cruz · Angel M. Carcaboso · Michelle Monje · Alan Mackay · Chris Jones · Chris Jones
A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism Luigina Romani · Vasilis Oikonomou · Silvia Moretti · Rossana G. Iannitti · Maria Cristina D’Adamo · Valeria Rachela Villella · Marilena Pariano · Luigi Sforna · Monica Borghi · Marina Maria Bellet · Francesca Fallarino · Maria Teresa Pallotta · Giuseppe Servillo · Eleonora Ferrari · Paolo Puccetti · Guido Kroemer · Mauro Pessia · Mauro Pessia · Luigi Maiuri · Allan L. Goldstein · Enrico Garaci · Enrico Garaci
Recurrent ECSIT mutation encoding V140A triggers hyperinflammation and promotes hemophagocytic syndrome in extranodal NK/T cell lymphoma Yan-Xiao Ji · Zan Huang · Xia Yang · Xiaozhan Wang · Ling-Ping Zhao · Pi-Xiao Wang · Xiao-Jing Zhang · Michele Alves-Bezerra · Lin Cai · Peng Zhang · Yue-Xin Lu · Lan Bai · Mao-Mao Gao · Huan Zhao · Song Tian · Yong Wang · Zhi-Xiang Huang · Xueyong Zhu · Yan Zhang · Jun Gong · Zhi-Gang She · Feng Li · David E. Cohen · Hongliang Li · Hongliang Li
Microbiome metabolomics reveals new drivers of human liver steatosis Bjoern Chapuy · Chip Stewart · Andrew Dunford · Jaegil Kim · Atanas Kamburov · Robert Redd · Michael S. Lawrence · Michael S. Lawrence · Margaretha G. M. Roemer · Amy Li · Marita Ziepert · Annette M. Staiger · Jeremiah Wala · Matthew Ducar · Ignaty Leshchiner · Ester Rheinbay · Amaro Taylor-Weiner · Caroline A. Coughlin · Julian Hess · Chandra S. Pedamallu · Dimitri Livitz · Daniel Rosebrock · Mara Rosenberg · Adam Tracy · Heike Horn · Paul Van Hummelen · Andrew L. Feldman · Brian K. Link · Anne J. Novak · James R. Cerhan · Thomas M. Habermann · Reiner Siebert · Andreas Rosenwald · Aaron R. Thorner · Matthew Meyerson · Matthew Meyerson · Todd R. Golub · Todd R. Golub · Rameen Beroukhim · Rameen Beroukhim · Gerald Wulf · German Ott · Scott J. Rodig · Scott J. Rodig · Stefano Monti · Donna Neuberg · M. Loeffler · Michael Pfreundschuh · Lorenz Trümper · Gad Getz · Gad Getz · Margaret A. Shipp · Margaret A. Shipp
In utero correction of a genetic disorder Daniela S. Thommen · Viktor H. Koelzer · Petra Herzig · Andreas Roller · Marcel Trefny · Sarah Dimeloe · Anna Kiialainen · Jonathan Hanhart · Catherine Schill · Christoph Hess · Spasenija Savic Prince · Mark Wiese · Didier Lardinois · Ping-Chih Ho · Christian Klein · Vaios Karanikas · Kirsten D. Mertz · Ton N. M. Schumacher · Alfred Zippelius · Alfred Zippelius
CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response Nikolaos Zacharakis · Harshini Chinnasamy · Mary A. Black · Hui Xu · Yong-Chen Lu · Zhili Zheng · Anna Pasetto · Michelle M. Langhan · Thomas E. Shelton · Todd D. Prickett · Jared J. Gartner · Li Jia · Katarzyna Trebska-McGowan · Robert Somerville · Paul F. Robbins · Steven A. Rosenberg · Stephanie L. Goff · Steven A. Feldman · Steven A. Feldman
Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer Donn Colby · Lydie Trautmann · Lydie Trautmann · Suteeraporn Pinyakorn · Suteeraporn Pinyakorn · Louise Leyre · Amélie Pagliuzza · Eugene Kroon · Morgane Rolland · Morgane Rolland · Hiroshi Takata · Hiroshi Takata · Supranee Buranapraditkun · Jintana Intasan · Nitiya Chomchey · Roshell Muir · Elias K. Haddad · Sodsai Tovanabutra · Sodsai Tovanabutra · Sasiwimol Ubolyam · Diane L. Bolton · Diane L. Bolton · Brandie A. Fullmer · Robert J. Gorelick · Lawrence Fox · Trevor A. Crowell · Trevor A. Crowell · Rapee Trichavaroj · Robert J. O’Connell · Nicolas Chomont · Jerome H. Kim · Jerome H. Kim · Nelson L. Michael · Merlin L. Robb · Merlin L. Robb · Nittaya Phanuphak · Jintanat Ananworanich · Jintanat Ananworanich
Rapid HIV RNA rebound after antiretroviral treatment interruption in persons durably suppressed in Fiebig I acute HIV infection Robert J. Ihry · Kathleen A. Worringer · Max R. Salick · Elizabeth Frias · Daniel Ho · Kraig Theriault · Sravya Kommineni · Julie Chen · Marie Sondey · Chaoyang Ye · Ranjit Randhawa · Tripti Kulkarni · Zinger Yang · Gregory McAllister · Carsten Russ · John S. Reece-Hoyes · William Forrester · Gregory R. Hoffman · Ricardo E. Dolmetsch · Ajamete Kaykas · Ajamete Kaykas
p53 inhibits CRISPR–Cas9 engineering in human pluripotent stem cells Seung Pil Yun · Tae-In Kam · Nikhil Panicker · SangMin Kim · Yumin Oh · Jong-Sung Park · Seung-Hwan Kwon · Yong Joo Park · Senthilkumar S. Karuppagounder · Hyejin Park · Sangjune Kim · Nayeon Oh · Nayoung Alice Kim · Saebom Lee · Saurav Brahmachari · Xiaobo Mao · Jun Hee Lee · Manoj Kumar · Daniel An · Sung-Ung Kang · Yunjong Lee · Kang Choon Lee · Dong Hee Na · Donghoon Kim · Sang Hun Lee · Viktor V. Roschke · Shane A. Liddelow · Zoltan Mari · Ben A. Barres · Valina L. Dawson · Seulki Lee · Ted M. Dawson · Hanseok Ko · Hanseok Ko
Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinsons disease Hannah Stower · Hannah Stower
Tracing clear cell renal carcinoma evolution Hannah Stower · Hannah Stower
A transcriptionally and functionally distinct PD-1 + CD8 + T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade Dhakshin S. Ramanathan · Ling Guo · Ling Guo · Tanuj Gulati · Tanuj Gulati · Gray Davidson · Gray Davidson · April K. Hishinuma · April K. Hishinuma · Seok-Joon Won · Seok-Joon Won · Robert T. Knight · Robert T. Knight · Edward F. Chang · Raymond A. Swanson · Raymond A. Swanson · Karunesh Ganguly · Karunesh Ganguly · Karunesh Ganguly
Single-cell profiling of breast cancer T cells reveals a tissue-resident memory subset associated with improved prognosis Elizabeth Matthes · John W. Hanrahan · André M. Cantin · André M. Cantin · André M. Cantin
Low-frequency cortical activity is a neuromodulatory target that tracks recovery after stroke Xinyi Guo · Yuanyuan Zhang · Liangtao Zheng · Chunhong Zheng · Jintao Song · Qiming Zhang · Boxi Kang · Zhouzerui Liu · Liang Jin · Rui Xing · Ranran Gao · Minghui Dong · Xueda Hu · Xianwen Ren · Dennis Kirchhoff · Helge Gottfried Roider · Tiansheng Yan · Zemin Zhang · Zemin Zhang
Global characterization of T cells in non-small-cell lung cancer by single-cell sequencing Worthmann Anna · John Clara · Baguhl Miriam · Schaltenberg Nicola · Heine Markus · Schlein Christian · Evangelakos Ioannis · Scheja Ludger · Heeren Joerg · Ruehlemann Malte C · Heinsen Femke‐Anouska · Franke Andre · Mineo Chieko · Shaul Philip W · Fischer Markus · Dandri Maura · Kremoser Claus · Kremoser Claus
Reply to F508del-CFTR is not corrected by thymosin α1 Kevin C. Barry · Joy Hsu · Miranda Broz · Francisco J. Cueto · Francisco J. Cueto · Francisco J. Cueto · Mikhail Binnewies · Alexis J. Combes · Amanda E. Nelson · Kimberly Loo · Raj Kumar · Michael D. Rosenblum · Michael Alvarado · Denise M. Wolf · Dusan Bogunovic · Nina Bhardwaj · Adil Daud · Patrick K. Ha · William R. Ryan · Joshua L. Pollack · Bushra Samad · Saurabh Asthana · Vincent Chan · Matthew F. Krummel · Matthew F. Krummel
A natural killer-dendritic cell axis defines checkpoint therapy-responsive tumor microenvironments Ludivine Laurans · Nicolas Venteclef · Yacine Haddad · Mouna Chajadine · Fawaz Alzaid · Sarvenaz Metghalchi · Bruno Sovran · R. Denis · Julien Dairou · Marina Cardellini · Jose-Maria Moreno-Navarrete · Marjolene Straub · Sarah Jegou · Claire McQuitty · Thomas Viel · Bruno Esposito · Bertrand Tavitian · Jacques Callebert · Serge Luquet · Massimo Federici · José Manuel Fernández-Real · Rémy Burcelin · Jean-Marie Launay · Alain Tedgui · Ziad Mallat · Ziad Mallat · Harry Sokol · Harry Sokol · Harry Sokol · Soraya Taleb · Soraya Taleb
Genetic deficiency of indoleamine 2,3-dioxygenase promotes gut microbiota-mediated metabolic health Sanghee Yun · Sanghee Yun · Ryan P. Reynolds · Iraklis Petrof · Alicia White · Phillip D. Rivera · Phillip D. Rivera · Amir Segev · Adam D. Gibson · Maiko Suarez · Matthew J. DeSalle · Naoki Ito · Naoki Ito · Shibani Mukherjee · Devon R. Richardson · Catherine E. Kang · Rebecca C. Ahrens-Nicklas · Ivan Soler · Ivan Soler · Dane M. Chetkovich · Dane M. Chetkovich · Saïd Kourrich · Douglas A. Coulter · Douglas A. Coulter · Amelia J. Eisch · Amelia J. Eisch · Amelia J. Eisch · Amelia J. Eisch
Publisher Correction: Stimulation of entorhinal cortex–dentate gyrus circuitry is antidepressive Peter Savas · Peter Savas · Balaji Virassamy · Chengzhong Ye · Chengzhong Ye · Agus Salim · Christopher P. Mintoff · Franco Caramia · Roberto Salgado · David J. Byrne · Zhi L. Teo · Zhi L. Teo · Sathana Dushyanthen · Ann Byrne · Lironne Wein · Stephen J. Luen · Catherine Poliness · Sophie S. Nightingale · Anita S. Skandarajah · Anita S. Skandarajah · David E. Gyorki · Chantel M. Thornton · Paul A. Beavis · Paul A. Beavis · Stephen B. Fox · Stephen B. Fox · Phillip K. Darcy · Phillip K. Darcy · Terence P. Speed · Laura K. Mackay · Paul Neeson · Paul Neeson · Sherene Loi · Sherene Loi · Sherene Loi
Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells Nathalie M. Delzenne · Laure B. Bindels · Laure B. Bindels
Publisher Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes Dawn M. Dudley · Koen K. A. Van Rompay · Koen K. A. Van Rompay · Lark L. Coffey · Amir Ardeshir · Rebekah I. Keesler · Eliza Bliss-Moreau · Peta L. Grigsby · Rosemary Steinbach · Alec J. Hirsch · Alec J. Hirsch · Rhonda MacAllister · Heidi L. Pecoraro · Lois M. A. Colgin · Travis Hodge · Daniel N. Streblow · Daniel N. Streblow · Suzette D. Tardif · Jean L. Patterson · Manasi Tamhankar · Maxim D. Seferovic · Kjersti Aagaard · Claudia Sánchez-San Martín · Charles Y. Chiu · Antonito T. Panganiban · Ronald S. Veazey · Xiaolei Wang · Nicholas J. Maness · Margaret H. Gilbert · Rudolf P. Bohm · Kristina M. Adams Waldorf · Michael Gale · Lakshmi Rajagopal · Lakshmi Rajagopal · Charlotte E. Hotchkiss · Emma L. Mohr · Saverio Capuano · Heather A. Simmons · Andres Mejia · Thomas C. Friedrich · Thaddeus G. Golos · David H. O’Connor · David H. O’Connor
SHP2 inhibition restores sensitivity in ALK -rearranged non-small-cell lung cancer resistant to ALK inhibitors Anna Azvolinsky · Anna Azvolinsky
Congenital Zika virus infection as a silent pathology with loss of neurogenic output in the fetal brain Alexander Bartelt · Scott B. Widenmaier · Christian Schlein · Kornelia Johann · Renata L.S. Goncalves · Kosei Eguchi · Alexander W. Fischer · Güneş Parlakgül · Nicole Snyder · Truc Nguyen · Oliver T. Bruns · Daniel Franke · Moungi G. Bawendi · Matthew D. Lynes · Luiz O Leiria · Yu-Hua Tseng · Karen Inouye · Ana Paula Arruda · Gökhan S. Hotamisligil · Gökhan S. Hotamisligil
Puzzling over privilege: How the immune system protects—and fails—the testes Vineet D. Menachery · Boyd Yount · Kari Debbink · Sudhakar Agnihothram · Lisa E. Gralinski · Jessica A. Plante · Rachel L. Graham · Trevor Scobey · Xing-Yi Ge · Eric F. Donaldson · Scott H. Randell · Antonio Lanzavecchia · Wayne A. Marasco · Zhengli-Li Shi · Ralph S. Baric · Ralph S. Baric
Genomics in childhood acute myeloid leukemia comes of age Mark J. Kwakkenbos · Sean A. Diehl · Etsuko Yasuda · Arjen Q. Bakker · Caroline M. M. van Geelen · Michaël V. Lukens · Grada M. van Bleek · Myra N. Widjojoatmodjo · Willy M. J. M. Bogers · Henrik E. Mei · Andreas Radbruch · Ferenc A. Scheeren · Hergen Spits · Tim Beaumont · Tim Beaumont
Selective enhancer changes in osteosarcoma lung metastasis Stephen M. Carpenter · Samuel M. Behar · Samuel M. Behar
A new vaccine for tuberculosis in rhesus macaques Sangeeta Goswami · Sreyashi Basu · Padmanee Sharma · Padmanee Sharma
A potential biomarker for anti-PD-1 immunotherapy Axel Montagne · Angeliki M. Nikolakopoulou · Zhen Zhao · Abhay P. Sagare · Gabriel Si · Divna Lazic · Samuel R. Barnes · Madelaine Daianu · Anita Ramanathan · Ariel Go · Erica J. Lawson · Yaoming Wang · William J. Mack · Paul M. Thompson · Julie A. Schneider · Jobin Varkey · Ralf Langen · Eric Mullins · Russell E. Jacobs · Berislav V. Zlokovic · Berislav V. Zlokovic
Pericyte degeneration causes white matter dysfunction in the mouse central nervous system Kristina M. Adams Waldorf · Branden R. Nelson · Jennifer Stencel-Baerenwald · Colin Studholme · Raj P. Kapur · Blair Armistead · Christie Walker · Sean Merillat · Jay Vornhagen · Jennifer Tisoncik-Go · Audrey Baldessari · Michelle Coleman · Manjiri Dighe · Dennis W. W. Shaw · Justin A. Roby · Veronica Santana-Ufret · Erica Boldenow · Junwei Li · Xiaohu Gao · Michael A. Davis · Jesica Swanstrom · Kara Jensen · Douglas G. Widman · Ralph S. Baric · Joseph T Medwid · Kathryn A Hanley · Jason Ogle · G. Michael Gough · Wonsok Lee · Chris English · W McIntyre Durning · Jeff Thiel · Chris Gatenby · Elyse C. Dewey · Marian R. Fairgrieve · Rebecca D. Hodge · Richard Grant · LaRene Kuller · William B. Dobyns · Robert F. Hevner · Michael Gale · Lakshmi Rajagopal · Lakshmi Rajagopal
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity Dominik Hartl · Dominik Hartl
Prevention of tuberculosis in rhesus macaques by a cytomegalovirus-based vaccine Satdarshan P Monga · Satdarshan P Monga
Macrophages and platelets join forces to release kidney-damaging DNA traps Yingxiao Shi · Shaoyu Lin · Kim Staats · Yichen Li · Wen Hsuan Chang · Shu Ting Hung · Eric Hendricks · Gabriel R. Linares · Yaoming Wang · Esther Y. Son · Xinmei Wen · Kassandra Kisler · Brent Wilkinson · Louise Menendez · Tohru Sugawara · Phillip Woolwine · Mickey Huang · Michael J. Cowan · Brandon Ge · Nicole Koutsodendris · Kaitlin P. Sandor · Jacob Komberg · Vamshidhar R. Vangoor · Ketharini Senthilkumar · Valerie Hennes · Carina Seah · Amy R. Nelson · Tze Yuan Cheng · Shih Jong J. Lee · Paul R. August · Jason A. Chen · Nicholas Wisniewski · Victor Hanson-Smith · T. Grant Belgard · Alice Zhang · Marcelo P. Coba · Chris Grunseich · Michael E. Ward · Leonard H. van den Berg · R. Jeroen Pasterkamp · Davide Trotti · Berislav V. Zlokovic · Justin K. Ichida · Justin K. Ichida
Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons Adrian Pickar · Charles A. Gersbach · Charles A. Gersbach
Gene therapies for hemophilia hit the mark in clinical trials Bin Guo · Xinxin Huang · Man Ryul Lee · Sang A. Lee · Hal E. Broxmeyer · Hal E. Broxmeyer
Antagonism of PPAR-γ signaling expands human hematopoietic stem and progenitor cells by enhancing glycolysis Ramon J. Whitson · Alex G. Lee · Nicole M. Urman · Amar Mirza · C.Y. Yao · Alexander S Brown · Jiang R. Li · Gautam Shankar · Micah A. Fry · Scott X. Atwood · Eunice Y. Lee · S. Tyler Hollmig · Sumaira Z. Aasi · Kavita Y. Sarin · Matthew P. Scott · Ervin H. Epstein · Jean Y. Tang · Anthony E. Oro · Anthony E. Oro
Noncanonical hedgehog pathway activation through SRF–MKL1 promotes drug resistance in basal cell carcinomas Yuki Kagoya · Shinya Tanaka · Tingxi Guo · Mark Anczurowski · Chung-Hsi Wang · Kayoko Saso · Marcus O. Butler · Mark D. Minden · Naoto Hirano · Naoto Hirano
A novel chimeric antigen receptor containing a JAK–STAT signaling domain mediates superior antitumor effects Laura S Shankman · Delphine Gomez · Olga A Cherepanova · Morgan Salmon · Gabriel F. Alencar · Ryan M Haskins · Pamela Swiatlowska · Alexandra A C Newman · Elizabeth S Greene · Adam C. Straub · Brant E. Isakson · Gwendalyn J. Randolph · Gary K. Owens · Gary K. Owens
Lipid metabolic reprogramming in hepatic ischemia–reperfusion injury Shraddha Chakradhar · Shraddha Chakradhar
Transitory presence of myeloid-derived suppressor cells in neonates is critical for control of inflammation Andrew S. Ishizuka · Kirsten E. Lyke · Adam DeZure · Andrea A. Berry · Thomas L. Richie · Floreliz Mendoza · Mary E. Enama · Ingelise J. Gordon · Lee-Jah Chang · Uzma N Sarwar · Kathryn L. Zephir · LaSonji A. Holman · Eric R. James · Peter F. Billingsley · Anusha Gunasekera · Sumana Chakravarty · Anita Manoj · Minglin Li · Adam Ruben · Tao Li · Abraham G. Eappen · Richard E. Stafford · Natasha K C · Tooba Murshedkar · Hope DeCederfelt · Sarah Plummer · Cynthia S. Hendel · Laura Novik · Pamela Costner · Jamie G. Saunders · Matthew B. Laurens · Christopher V. Plowe · Barbara J. Flynn · William R Whalen · J P Todd · Jay Noor · Srinivas S. Rao · Kailan Sierra-Davidson · Geoffrey M. Lynn · Judith E. Epstein · Margaret A. Kemp · Gary A. Fahle · Sebastian A. Mikolajczak · Matthew Fishbaugher · Brandon K. Sack · Stefan H. I. Kappe · Silas A. Davidson · Lindsey S Garver · Niklas K. Björkström · Martha Nason · Barney S. Graham · Mario Roederer · B. Kim Lee Sim · Stephen L. Hoffman · Julie E. Ledgerwood · Robert A. Seder · Robert A. Seder
Miscarriage and stillbirth following maternal Zika virus infection in nonhuman primates Bjoern Chapuy · Chip Stewart · Andrew Dunford · Jaegil Kim · Atanas Kamburov · Robert Redd · Michael S. Lawrence · Michael S. Lawrence · Margaretha G. M. Roemer · Amy Li · Marita Ziepert · Annette M. Staiger · Annette M. Staiger · Jeremiah Wala · Matthew Ducar · Ignaty Leshchiner · Ester Rheinbay · Amaro Taylor-Weiner · Caroline A. Coughlin · Julian Hess · Chandra S. Pedamallu · Dimitri Livitz · Daniel Rosebrock · Mara Rosenberg · Adam Tracy · Heike Horn · Paul Van Hummelen · Andrew L. Feldman · Brian K. Link · Anne J. Novak · James R. Cerhan · Thomas M. Habermann · Reiner Siebert · Andreas Rosenwald · Aaron R. Thorner · Matthew Meyerson · Matthew Meyerson · Todd R. Golub · Todd R. Golub · Rameen Beroukhim · Rameen Beroukhim · Gerald Wulf · German Ott · Scott J. Rodig · Scott J. Rodig · Stefano Monti · Donna Neuberg · Markus Loeffler · Michael Pfreundschuh · Lorenz Trümper · Gad Getz · Gad Getz · Margaret A. Shipp · Margaret A. Shipp
Diverse genetic-driven immune landscapes dictate tumor progression through distinct mechanisms Carsten Linnemann · Marit M. van Buuren · Laura Bies · Els M. E. Verdegaal · Remko Schotte · Jorg J A Calis · Sam Behjati · Arno Velds · Henk Hilkmann · Dris El Atmioui · Marten Visser · Michael R. Stratton · John B. A. G. Haanen · Hergen Spits · Sjoerd H. van der Burg · Ton N. M. Schumacher · Ton N. M. Schumacher
Author Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes Carsten Krieg · Carsten Krieg · Malgorzata Nowicka · Malgorzata Nowicka · Silvia Guglietta · Sabrina Schindler · Felix J. Hartmann · Lukas M. Weber · Lukas M. Weber · Reinhard Dummer · Mark D. Robinson · Mark D. Robinson · Mitchell P. Levesque · Burkhard Becher · Burkhard Becher
Author Correction: High-dimensional single-cell analysis predicts response to anti-PD-1 immunotherapy Fyodor D. Urnov · Fyodor D. Urnov
A path to efficient gene editing Meera Murgai · Wei Ju · Matthew Eason · Jessica Kline · Daniel W Beury · Sabina Kaczanowska · Markku Miettinen · Michael Kruhlak · Haiyan Lei · Jack F. Shern · Olga A Cherepanova · Gary K. Owens · Rosandra N. Kaplan · Rosandra N. Kaplan
Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring Joshua N. Farr · Ming Xu · Megan M. Weivoda · David G. Monroe · Daniel G. Fraser · Jennifer L Onken · Brittany A Negley · Jad G. Sfeir · Mikolaj Ogrodnik · Christine M Hachfeld · Nathan K. LeBrasseur · Matthew T. Drake · Robert J. Pignolo · Tamar Pirtskhalava · Tamara Tchkonia · Merry Jo Oursler · James L. Kirkland · Sundeep Khosla · Sundeep Khosla
Classification and mutation prediction from non–small cell lung cancer histopathology images using deep learning Chad E. Mire · Robert W. Cross · Joan B. Geisbert · Viktoriya Borisevich · Krystle N. Agans · Daniel J. Deer · Megan L. Heinrich · Megan M. Rowland · Augustine Goba · Mambu Momoh · Mathew L Boisen · Donald S. Grant · Mohamed Fullah · Sheik Humarr Khan · Karla A. Fenton · James E. Robinson · Luis M. Branco · Robert F. Garry · Thomas W. Geisbert · Thomas W. Geisbert
The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis Vineet D. Menachery · Boyd Yount · Kari Debbink · Sudhakar Agnihothram · Lisa E. Gralinski · Jessica A. Plante · Rachel L. Graham · Trevor Scobey · Xing Yi Ge · Eric F. Donaldson · Scott H. Randell · Antonio Lanzavecchia · Wayne A. Marasco · Zhengli Li Shi · Ralph S. Baric · Ralph S. Baric
Cooperative targeting of melanoma heterogeneity with an AXL antibody-drug conjugate and BRAF/MEK inhibitors Pinkal Desai · Nuria Mencia-Trinchant · Oleksandr Savenkov · Michael S. Simon · Gloria Cheang · Sangmin Lee · Michael Samuel · Ellen K. Ritchie · Monica L. Guzman · Karla V. Ballman · Gail J. Roboz · Duane C. Hassane · Duane C. Hassane
Positively selected enhancer elements endow osteosarcoma cells with metastatic competence Yu-Mei He · Xing Li · Yulia Nefedova · Andrew V. Kossenkov · Erik A. Jensen · Valerian E. Kagan · Yufeng Liu · Shuyu Fu · Qing-Jian Ye · Yan-Hong Zhou · Lai Wei · Dmitry I. Gabrilovich · Jie Zhou · Jie Zhou
Somatic mutations precede acute myeloid leukemia years before diagnosis Marc L. Hyer · Michael Milhollen · Jeff Ciavarri · Paul Fleming · Tary Traore · Darshan S. Sappal · Jessica Huck · Judy Shi · James M. Gavin · Jim Brownell · Yu Yang · Bradley Stringer · Robert S. Griffin · Frank J. Bruzzese · Teresa A. Soucy · Jennifer Duffy · Claudia Rabino · Jessica Riceberg · Kara M. Hoar · Anya Lublinsky · Saurabh Menon · Michael D. Sintchak · Nancy J. Bump · Sai M Pulukuri · Steve Langston · Stephen Tirrell · Mike Kuranda · Petter Veiby · John Newcomb · Ping Li · Jing Tao Wu · Josh Powe · Lawrence R. Dick · Paul D. Greenspan · Katherine M. Galvin · Mark Manfredi · Chris Claiborne · Benjamin S. Amidon · Neil F. Bence · Neil F. Bence
A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment Kathrin U. Jansen · Charles Knirsch · Annaliesa S. Anderson · Annaliesa S. Anderson
The role of vaccines in preventing bacterial antimicrobial resistance Koshu Okubo · Miho Kurosawa · Mako Kamiya · Yasuteru Urano · Akari Suzuki · Kazuhiko Yamamoto · Koji Hase · Koichiro Homma · Junichi Sasaki · Hiroaki Miyauchi · Tatsuo Hoshino · Matsuhiko Hayashi · Tanya N. Mayadas · Junichi Hirahashi · Junichi Hirahashi
Macrophage extracellular trap formation promoted by platelet activation is a key mediator of rhabdomyolysis-induced acute kidney injury Nicole Wetsman · Nicole Wetsman
Suppression of luteinizing hormone enhances HSC recovery after hematopoietic injury Andrew S. Ishizuka · Kirsten E. Lyke · Adam DeZure · Andrea A. Berry · Thomas L. Richie · Floreliz Mendoza · Mary E. Enama · Ingelise J. Gordon · Lee Jah Chang · Uzma N Sarwar · Kathryn L. Zephir · La Sonji A Holman · Eric R. James · Peter F. Billingsley · Anusha Gunasekera · Sumana Chakravarty · Anita Manoj · Ming Lin Li · Adam Ruben · Tao Li · Abraham G. Eappen · Richard E. Stafford · K. C. Natasha · Tooba Murshedkar · Hope DeCederfelt · Sarah Plummer · Cynthia S. Hendel · Laura Novik · Pamela Costner · Jamie G. Saunders · Matthew B. Laurens · Christopher V. Plowe · Barbara J. Flynn · William R Whalen · J P Todd · Jay Noor · Srinivas S. Rao · Kailan Sierra-Davidson · Geoffrey M. Lynn · Judith E. Epstein · Margaret A. Kemp · Gary A. Fahle · Sebastian A. Mikolajczak · Matthew Fishbaugher · Brandon K. Sack · Stefan H. I. Kappe · Silas A. Davidson · Lindsey S Garver · Niklas K. Björkström · Martha Nason · Barney S. Graham · Mario Roederer · B. Kim Lee Sim · Stephen L. Hoffman · Julie E. Ledgerwood · Robert A. Seder · Robert A. Seder
Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models James J. Morrow · Ian Bayles · Alister P.W. Funnell · Tyler E. Miller · Alina Saiakhova · Michael M. Lizardo · Cynthia F. Bartels · Maaike Y. Kapteijn · Stevephen Hung · Arnulfo Mendoza · Gursimran Dhillon · Daniel R. Chee · Jay Myers · Frederick Allen · Marco Gambarotti · Alberto Righi · Analisa DiFeo · Brian P. Rubin · Alex Y. Huang · Paul S. Meltzer · Lee J. Helman · Piero Picci · Henri H. Versteeg · John A. Stamatoyannopoulos · Chand Khanna · Peter C. Scacheri · Peter C. Scacheri
What models eat Emma Haapaniemi · Emma Haapaniemi · Sandeep Kumar Botla · Jenna Persson · Bernhard Schmierer · Jussi Taipale · Jussi Taipale · Jussi Taipale · Jussi Taipale
STAT3 labels a subpopulation of reactive astrocytes required for brain metastasis Daniel Engber · Daniel Engber
CRISPR-based diagnostics Neibla Priego · Lucía Zhu · Cátia Monteiro · Manon Mulders · David Wasilewski · Wendy Bindeman · Laura Doglio · Liliana Martínez · Elena Martinez-Saez · Santiago Ramón y Cajal · Diego Megías · Elena Hernández-Encinas · Carmen Blanco-Aparicio · Lola Martínez · Eduardo Zarzuela · Javier Muñoz · Coral Fustero-Torre · Elena Piñeiro-Yáñez · Aurelio Hernández-Laín · Luca Bertero · Valeria Poli · Melchor Sanchez-Martinez · Javier A. Menendez · Riccardo Soffietti · Joaquim Bosch-Barrera · Manuel Valiente · Manuel Valiente
Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia Jacqulyne P. Robichaux · Yasir Elamin · Zhi Tan · Brett W. Carter · Shuxing Zhang · Shengwu Liu · Shuai Li · Ting Chen · Alissa Poteete · Adriana Estrada-Bernal · Anh T. Le · Anna Truini · Monique B. Nilsson · Huiying Sun · Emily Roarty · Sarah B. Goldberg · Julie R. Brahmer · Mehmet Altan · Charles Lu · Vassiliki Papadimitrakopoulou · Katerina Politi · Robert C. Doebele · Kwok-Kin Wong · John V. Heymach · John V. Heymach
Antidepressive effects of targeting ELK-1 signal transduction Julia E. Neumann · Julia E. Neumann · Julia E. Neumann · Annika K. Wefers · Annika K. Wefers · Annika K. Wefers · Sander Lambo · Edoardo Bianchi · Marie Bockstaller · Mario M. Dorostkar · Valerie Meister · Pia Schindler · Andrey Korshunov · Katja von Hoff · Johannes Nowak · Johannes Nowak · Monika Warmuth-Metz · Marlon R. Schneider · Ingrid Renner-Müller · Daniel Merk · Mehdi Shakarami · Tanvi S. Sharma · Tanvi S. Sharma · Lukas Chavez · Rainer Glass · Jennifer A. Chan · Makoto M. Taketo · Philipp Neumann · Marcel Kool · Ulrich Schüller · Ulrich Schüller · Ulrich Schüller
Targeting sphingosine-1-phosphate lyase as an anabolic therapy for bone loss Mikhail Binnewies · Edward W. Roberts · Kelly Kersten · Vincent Chan · Douglas F. Fearon · Miriam Merad · Lisa M. Coussens · Dmitry I. Gabrilovich · Suzanne Ostrand-Rosenberg · Suzanne Ostrand-Rosenberg · Catherine C. Hedrick · Robert H. Vonderheide · Mikael J. Pittet · Rakesh K. Jain · Weiping Zou · T. Kevin Howcroft · Elisa C. Woodhouse · Robert A. Weinberg · Matthew F. Krummel · Matthew F. Krummel
Understanding the tumor immune microenvironment (TIME) for effective therapy Paul Hiebert · Sabine Werner · Sabine Werner
Targeting metabolism to treat psoriasis Ansuman T. Satpathy · Naresha Saligrama · Jason D. Buenrostro · Jason D. Buenrostro · Yuning Wei · Beijing Wu · Adam J Rubin · Jeffrey M. Granja · Caleb A. Lareau · Rui Li · Yanyan Qi · Kevin R. Parker · Maxwell R. Mumbach · William S. Serratelli · David Gennert · Alicia N. Schep · M. Ryan Corces · Michael S. Khodadoust · Youn H. Kim · Paul A. Khavari · William J. Greenleaf · Mark M. Davis · Howard Y. Chang · Howard Y. Chang
Transcript-indexed ATAC-seq for precision immune profiling Jose V. Sanchez-Mut · Holger Heyn · Bianca A. Silva · Lucie Dixsaut · Paula Garcia-Esparcia · Enrique Vidal · Sergi Sayols · Liliane Glauser · Ana Monteagudo-Sánchez · Jordi Pérez-Tur · Isidre Ferrer · David Monk · Bernard L. Schneider · Manel Esteller · Johannes Gräff · Johannes Gräff
PM20D1 is a quantitative trait locus associated with Alzheimers disease Joseph A. Fraietta · Simon F. Lacey · Elena Orlando · Iulian Pruteanu-Malinici · Mercy Gohil · Stefan Lundh · Alina C. Boesteanu · Yan Wang · Roddy S. O’Connor · Wei-Ting Hwang · Edward Pequignot · David E Ambrose · Changfeng Zhang · Nicholas Wilcox · Felipe Bedoya · Corin Dorfmeier · Fang Chen · Lifeng Tian · Harit Parakandi · Minnal Gupta · Regina M. Young · F. Brad Johnson · Irina Kulikovskaya · Li Liu · Jun Xu · Sadik Kassim · Megan M. Davis · Bruce L. Levine · Noelle V. Frey · Don L. Siegel · Alexander C. Huang · E. John Wherry · Hans Bitter · Jennifer Brogdon · David L. Porter · Carl H. June · J. Joseph Melenhorst · J. Joseph Melenhorst
Mechanisms and clinical activity of an EGFR and HER2 exon 20–selective kinase inhibitor in non–small cell lung cancer Bjoern Chapuy · Chip Stewart · Andrew Dunford · Jaegil Kim · Atanas Kamburov · Robert Redd · Michael S. Lawrence · Michael S. Lawrence · Margaretha G. M. Roemer · Amy Li · Marita Ziepert · Annette M. Staiger · Annette M. Staiger · Jeremiah Wala · Matthew Ducar · Ignaty Leshchiner · Ester Rheinbay · Amaro Taylor-Weiner · Caroline A. Coughlin · Julian Hess · Chandra S. Pedamallu · Dimitri Livitz · Daniel Rosebrock · Mara Rosenberg · Adam Tracy · Heike Horn · Paul Van Hummelen · Andrew L. Feldman · Brian K. Link · Anne J. Novak · James R. Cerhan · Thomas M. Habermann · Reiner Siebert · Andreas Rosenwald · Aaron R. Thorner · Matthew Meyerson · Matthew Meyerson · Todd R. Golub · Todd R. Golub · Rameen Beroukhim · Rameen Beroukhim · Gerald Wulf · German Ott · Scott J. Rodig · Scott J. Rodig · Stefano Monti · Donna Neuberg · Markus Loeffler · Michael Pfreundschuh · Lorenz Trümper · Gad Getz · Gad Getz · Margaret A. Shipp · Margaret A. Shipp
Differential glucose requirement in skin homeostasis and injury identifies a therapeutic target for psoriasis Daniel S. W. Ting · Daniel S. W. Ting · Yong Liu · Philippe Burlina · Xinxing Xu · Neil M. Bressler · Tien Yin Wong · Tien Yin Wong
Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes Ana C. Garrido-Castro · Ana C. Garrido-Castro
Predicting breast cancer therapeutic response Andrew Tutt · Andrew Tutt · H Tovey · Maggie Cheang · Sarah Kernaghan · Lucy Kilburn · Patrycja Gazinska · Julie Owen · J Abraham · Sophie Barrett · Peter Barrett-Lee · Robert Brown · Robert Brown · Stephen Chan · Mitch Dowsett · Mitch Dowsett · James M. Flanagan · Lisa Fox · Anita Grigoriadis · Alexander Gutin · Catherine Harper-Wynne · M.Q. Hatton · K. A Hoadley · Jyoti Parikh · Peter J. Parker · Peter J. Parker · Charles M. Perou · R Roylance · Shah · Adam Shaw · Ian E. Smith · Kirsten Timms · Andrew M Wardley · Godfrey Wilson · Cheryl Gillett · Cheryl Gillett · Jerry S. Lanchbury · Alan Ashworth · Nazneen Rahman · Nazneen Rahman · Mark Harries · Paul Ellis · Sarah Pinder · Sarah Pinder · Judith M. Bliss · Judith M. Bliss
Carboplatin in BRCA1/2-mutated and triple-negative breast cancer BRCAness subgroups: the TNT Trial Vijay Ramaswamy · Michael D. Taylor · Michael D. Taylor
CAR T cells for childhood diffuse midline gliomas Lillian B. Cohn · Israel T. Silva · Renan Valieris · Amy S. Huang · Julio C. C. Lorenzi · Yehuda Z. Cohen · Joy Pai · Allison L. Butler · Marina Caskey · Mila Jankovic · Michel C. Nussenzweig · Michel C. Nussenzweig · Michel C. Nussenzweig
Clonal CD4 + T cells in the HIV-1 latent reservoir display a distinct gene profile upon reactivation Karine Clément · Heike Biebermann · I. Sadaf Farooqi · Lex H.T. Van der Ploeg · Barbara Wolters · Christine Poitou · Lia Puder · Fred Fiedorek · Keith Gottesdiener · Gunnar Kleinau · Nicolas Heyder · Patrick Scheerer · Ulrike Blume-Peytavi · Irina Jahnke · Shubh D. Sharma · Jacek Mokrosinski · Susanna Wiegand · Anne Müller · Katja Weiß · Knut Mai · Joachim Spranger · Annette Grüters · Oliver Blankenstein · Heiko Krude · Peter Kühnen · Peter Kühnen
MC4R agonism promotes durable weight loss in patients with leptin receptor deficiency Maria Maryanovich · Ali Zahalka · Halley Pierce · Sandra Pinho · Fumio Nakahara · Noboru Asada · Noboru Asada · Qiaozhi Wei · Xizhe Wang · Paul Ciero · Jianing Xu · Avigdor Leftin · Paul S. Frenette · Paul S. Frenette
AI for medical imaging goes deep Kallia Apazoglou · Severine Farley · Victor Gorgievski · Raoul Belzeaux · Juan Pablo Lopez · Julien Grenier · El Chérif Ibrahim · Marie-Anne El Khoury · Yiu C. Tse · Raphaele Mongredien · Alexandre Barbé · Carlos E. A. de Macedo · Wojciech Jaworski · Ariane Bochereau · Alejandro Orrico · Elsa Isingrini · Chloé Guinaudie · Lenka Mikasova · Franck Louis · Sophie Gautron · Laurent Groc · Charbel Massaad · Ferah Yildirim · Vincent Vialou · Sylvie Dumas · Fabio Marti · Naguib Mechawar · Elise Morice · Tak Pan Wong · Jocelyne Caboche · Gustavo Turecki · Bruno Giros · Bruno Giros · Eleni T. Tzavara · Eleni T. Tzavara
Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1 Zhuzhen Zhang · Zhenzhen Zi · Eunice E. Lee · Jiawei Zhao · Diana C. Contreras · Andrew P. South · E. Dale Abel · Benjamin F. Chong · Travis Vandergriff · Gregory A. Hosler · Philipp E. Scherer · Marcel Mettlen · Jeffrey C. Rathmell · Ralph J. DeBerardinis · Richard C. Wang · Richard C. Wang
Suppression of detyrosinated microtubules improves cardiomyocyte function in human heart failure Hannah Stower · Hannah Stower
A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein Ly P. Vu · Brian F. Pickering · Yuanming Cheng · Sara Zaccara · Diu Nguyen · Gerard Minuesa · Timothy Chou · Arthur Chow · Yogesh Saletore · Matthew MacKay · Jessica Schulman · Christopher Famulare · Minal Patel · Virginia M. Klimek · Francine E. Garrett-Bakelman · Ari Melnick · Martin Carroll · Christopher E. Mason · Samie R. Jaffrey · Michael G. Kharas · Michael G. Kharas
Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy Amritha Nair · Hsiang Ching Chung · Tingting Sun · Siddhartha Tyagi · Lacey E. Dobrolecki · Rocio Dominguez-Vidana · Sarah J. Kurley · Mayra Orellana · Alexander Renwick · David M. Henke · Panagiotis Katsonis · Earlene M. Schmitt · Doug W. Chan · Hui Li · Sufeng Mao · Ivana Petrovic · Chad J. Creighton · Carolina Gutierrez · Julien Dubrulle · Fabio Stossi · Jeffrey W. Tyner · Olivier Lichtarge · Charles Y. Lin · Bing Zhang · Kenneth L. Scott · Susan G. Hilsenbeck · Jin-Peng Sun · Xiao Yu · C. Kent Osborne · Rachel Schiff · James G. Christensen · David J. Shields · Mothaffar F. Rimawi · Matthew J. Ellis · Chad A. Shaw · Michael T. Lewis · Thomas F. Westbrook · Thomas F. Westbrook
Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer Bin Zhang · Le Xuan Truong Nguyen · Ling Li · Dandan Zhao · Bijender Kumar · Herman Wu · Allen Lin · Francesca Pellicano · Lisa Hopcroft · Yu-Lin Su · Mhairi Copland · Tessa L. Holyoake · Calvin J. Kuo · Ravi Bhatia · David S. Snyder · Haris Ali · Anthony S. Stein · Casey Brewer · Huafeng Wang · Tinisha McDonald · Piotr Swiderski · Estelle Troadec · Ching-Cheng Chen · Adrienne M. Dorrance · Vinod Pullarkat · Yate-Ching Yuan · Danilo Perrotti · Nadia Carlesso · Stephen J. Forman · Marcin Kortylewski · Ya-Huei Kuo · Guido Marcucci · Guido Marcucci
Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia Nannan Guo · Marta E. Soden · Charlotte Herber · Michael TaeWoo Kim · Antoine Besnard · Paoyan Lin · Xiang Ma · Constance L. Cepko · Larry S. Zweifel · Amar Sahay · Amar Sahay
Dentate granule cell recruitment of feedforward inhibition governs engram maintenance and remote memory generalization Lyle R. McKinnon · Lyle R. McKinnon · Lyle R. McKinnon · Lenine J. Liebenberg · Lenine J. Liebenberg · Nonhlanhla Yende-Zuma · Derseree Archary · Derseree Archary · Sinaye Ngcapu · Sinaye Ngcapu · Aida Sivro · Aida Sivro · Aida Sivro · Nico Nagelkerke · José Gerardo García Lerma · Angela D. M. Kashuba · Lindi Masson · Lindi Masson · Leila E. Mansoor · Quarraisha Abdool Karim · Quarraisha Abdool Karim · Salim Safurdeen. Abdool Karim · Salim Safurdeen. Abdool Karim · Jo Ann S. Passmore · Jo Ann S. Passmore · Jo Ann S. Passmore
Genital inflammation undermines the effectiveness of tenofovir gel in preventing HIV acquisition in women Xuelian He · Liguo Zhang · Luis F. Queme · Xuezhao Liu · Andrew Lu · Ronald R. Waclaw · Xinran Dong · Wenhao Zhou · Grahame J. Kidd · Sung Ok Yoon · Andres Buonanno · Joshua B. Rubin · Mei Xin · Klaus-Armin Nave · Bruce D. Trapp · Michael P. Jankowski · Q. Richard Lu · Q. Richard Lu · Q. Richard Lu
A histone deacetylase 3–dependent pathway delimits peripheral myelin growth and functional regeneration Joshua Tan · Brandon K. Sack · David Oyen · Isabelle Zenklusen · Luca Piccoli · Sonia Barbieri · Mathilde Foglierini · Chiara Silacci Fregni · Jessica Marcandalli · Said Jongo · Salim Abdulla · Laurent Perez · Giampietro Corradin · Luca Varani · Federica Sallusto · Betty Kim Lee Sim · Stephen L. Hoffman · Stefan H. I. Kappe · Claudia Daubenberger · Ian A. Wilson · Antonio Lanzavecchia · Antonio Lanzavecchia
A new site of attack for a malaria vaccine Steven A. Goldman · Steven A. Goldman
Precision identification of diverse bloodstream pathogens in the gut microbiome Ke Xu · Priyamvada Acharya · Rui Kong · Cheng Cheng · Gwo-Yu Chuang · Liu K · Mark K. Louder · Reda Rawi · Mallika Sastry · Chen-Hsiang Shen · Bin Zhang · Tongqing Zhou · Mangaiarkarasi Asokan · Robert T. Bailer · Michael Chambers · Xuejun Chen · Choi Cw · V.P. Dandey · Nicole A. Doria-Rose · Aliaksandr Druz · E.T. Eng · K. Farney · Kathryn E. Foulds · Hui Geng · Ivelin S. Georgiev · Jason Gorman · K.R. Hill · A.J. Jafari · Young Do Kwon · Yuping Lai · Thomas Lemmin · Krisha McKee · T.Y. Ohr · L. Ou · D. Peng · A.P. Rowshan · Zizhang Sheng · John-Paul Todd · Yaroslav Tsybovsky · E.G. Viox · Yaohui Wang · H. Wei · Yili Yang · A.F. Zhou · Rita E. Chen · L. Yang · Diana G. Scorpio · Adrian B. McDermott · Lawrence Shapiro · Lawrence Shapiro · B. Carragher · C.S. Potter · John R. Mascola · Peter D. Kwong · Peter D. Kwong · Peter D. Kwong
Transplanted neural progenitors bridge gaps to benefit cord–injured monkeys William Pao · Imola Fodor · Imola Fodor
Catalyzing the field of precision oncology, one basket at a time Jack A. Gilbert · Jack A. Gilbert · Jack A. Gilbert · Martin J. Blaser · J. Gregory Caporaso · Janet K. Jansson · Susan V. Lynch · Rob Knight · Rob Knight
Current understanding of the human microbiome Chengzhong Wang · Ramsey Najm · Qin Xu · Dah-Eun Jeong · David Walker · Maureen E. Balestra · Seo Yeon Yoon · Heidi Yuan · Gang Li · Zachary A. Miller · Bruce L. Miller · Mary J. Malloy · Yadong Huang · Yadong Huang
Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector Thomas J. Hope · Thomas J. Hope
Inflammation weakens HIV prevention Sanghee Yun · Sanghee Yun · Ryan P. Reynolds · Iraklis Petrof · Alicia White · Phillip D. Rivera · Phillip D. Rivera · Amir Segev · Adam D. Gibson · Maiko Suarez · Matthew J. DeSalle · Naoki Ito · Naoki Ito · Shibani Mukherjee · Devon R. Richardson · Catherine E. Kang · Rebecca C. Ahrens-Nicklas · Ivan Soler · Ivan Soler · Dane M. Chetkovich · Dane M. Chetkovich · Saïd Kourrich · Douglas A. Coulter · Douglas A. Coulter · Amelia J. Eisch · Amelia J. Eisch · Amelia J. Eisch · Amelia J. Eisch
Stimulation of entorhinal cortex–dentate gyrus circuitry is antidepressive Fiona B. Tamburini · Tessa M. Andermann · Ekaterina Tkachenko · Fiona Senchyna · Niaz Banaei · Ami S. Bhatt · Ami S. Bhatt
Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche Rajeev Gautam · Yoshiaki Nishimura · Natalie Gaughan · Anna Gazumyan · Till Schoofs · Alicia Buckler-White · Michael S. Seaman · Bruce J. Swihart · Dean Follmann · Michel C. Nussenzweig · Michel C. Nussenzweig · Malcolm A. Martin · Malcolm A. Martin
A single injection of crystallizable fragment domain–modified antibodies elicits durable protection from SHIV infection Jianfeng Shen · Zhenlin Ju · Wei Zhao · Lulu Wang · Yang Peng · Zhongqi Ge · Zachary D. Nagel · Jun Zou · Chen Wang · Prabodh Kapoor · Xiangyi Ma · Ding Ma · Jiyong Liang · Shumei Song · Jinsong Liu · Leona D. Samson · Jaffer A. Ajani · Guo Min Li · Han Liang · Xuetong Shen · Gordon B. Mills · Guang Peng · Guang Peng
ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade Christopher Mount · Robbie G. Majzner · Shree Sundaresh · Evan Arnold · Meena Kadapakkam · Samuel Haile · Louai Labanieh · Esther Hulleman · Pamelyn Woo · Skyler P. Rietberg · Hannes Vogel · Michelle Monje · Crystal L. Mackall · Crystal L. Mackall
Zika virus shedding in semen Yonathan Lissanu Deribe · Yuting Sun · Christopher Terranova · Fatima Khan · Juan Martinez-Ledesma · Guang Gao · Robert A. Mullinax · Tin Khor · Ningping Feng · Yu Hsi Lin · Chia Chin Wu · Claudia Reyes · Qian Peng · Frederick Robinson · Akira Inoue · Veena Kochat · Chang Gong Liu · John M. Asara · Cesar A. Moran · Florian Muller · Jing Wang · Bingliang Fang · Vali Papadimitrakopoulou · Ignacio I. Wistuba · Kunal Rai · Joseph R. Marszalek · P. Andrew Futreal · P. Andrew Futreal
Publisher Correction: Targeting hepatic glutaminase activity to ameliorate hyperglycemia David F. McDermott · Mahrukh Huseni · Michael B. Atkins · Robert J. Motzer · Brian I. Rini · Bernard Escudier · Lawrence Fong · Richard W. Joseph · Sumanta K. Pal · James Reeves · Mario Sznol · John D. Hainsworth · W.Kimryn Rathmell · Walter M. Stadler · Thomas E. Hutson · Martin Gore · Alain Ravaud · Sergio Bracarda · Cristina Suárez · Riccardo Danielli · Viktor Gruenwald · Toni K. Choueiri · Dorothee Nickles · Suchit Jhunjhunwala · Elisabeth Piault-Louis · Alpa Thobhani · Jiaheng Qiu · Daniel S. Chen · Priti Hegde · Christina Schiff · Gregg Fine · Thomas Powles · Thomas Powles
Clinical activity and molecular correlates of response to atezolizumab alone or in combination with bevacizumab versus sunitinib in renal cell carcinoma Geetika Bajpai · Caralin Schneider · Nicole Wong · Andrea L. Bredemeyer · Maarten Hulsmans · Matthias Nahrendorf · Slava Epelman · Daniel Kreisel · Yongjian Liu · Akinobu Itoh · Thirupura S. Shankar · Craig H. Selzman · Stavros G. Drakos · Kory J. Lavine · Kory J. Lavine
The human heart contains distinct macrophage subsets with divergent origins and functions Weidong Xiao · Guangping Gao · Chen Ling · Roland W. Herzog · Xiao Xiao · Xiao Xiao · Richard Jude Samulski · Richard Jude Samulski
Impact of neutralizing antibodies against AAV is a key consideration in gene transfer to nonhuman primates Rongya Tao · Caixia Wang · Oliver Stöhr · Wei Qiu · Yue Hu · Ji Miao · X. Charlie Dong · Sining Leng · Margaret A. Stefater · Nicholas Stylopoulos · Lin Lin · Kyle D. Copps · Morris F. White · Morris F. White
Inactivating hepatic follistatin alleviates hyperglycemia Margaret M. McCarthy · Margaret M. McCarthy
Intersection of schizophrenia genetics and placental complications Hannah Stower · Hannah Stower
Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer Gang Wang · Anup K. Biswas · Wanchao Ma · Manoj Kandpal · Courtney Coker · Paul M. Grandgenett · Michael A. Hollingsworth · Rinku Jain · Kurenai Tanji · Sara Lόpez-Pintado · Alain C. Borczuk · Doreen Hebert · Supak Jenkitkasemwong · Shintaro Hojyo · Ramana V. Davuluri · Mitchell D. Knutson · Toshiyuki Fukada · Swarnali Acharyya · Swarnali Acharyya
Potent antitumor efficacy of anti-GD2 CAR T cells in H3-K27M + diffuse midline gliomas Brooke Tata · Brooke Tata · Nour El Houda Mimouni · Nour El Houda Mimouni · Anne-Laure Barbotin · Samuel A. Malone · Samuel A. Malone · Anne Loyens · Anne Loyens · Pascal Pigny · Sophie Catteau-Jonard · Sophie Catteau-Jonard · Inger Sundström-Poromaa · Terhi Piltonen · Federica Dal Bello · C. Medana · Vincent Prevot · Vincent Prevot · Jerome Clasadonte · Jerome Clasadonte · Paolo Giacobini · Paolo Giacobini · Paolo Giacobini
Metastatic cancers promote cachexia through ZIP14 upregulation in skeletal muscle Peter Abbink · Rafael A. Larocca · Wanwisa Dejnirattisai · Rebecca Peterson · Joseph P. Nkolola · Erica N. Borducchi · Piyada Supasa · Juthathip Mongkolsapaya · Juthathip Mongkolsapaya · Gavin R. Screaton · Dan H. Barouch · Dan H. Barouch · Dan H. Barouch
Therapeutic and protective efficacy of a dengue antibody against Zika infection in rhesus monkeys Matthias Nahrendorf · Matthias Nahrendorf
Myeloid cell contributions to cardiovascular health and disease Jennifer R. Molina · Yuting Sun · Marina Protopopova · Sonal Gera · Madhavi Bandi · Christopher A. Bristow · Timothy McAfoos · Pietro Morlacchi · Pietro Morlacchi · Jeffrey Ackroyd · Ahmed Noor A. Agip · Gheath Alatrash · John M. Asara · Jennifer Bardenhagen · Caroline Carrillo · Christopher Carroll · Edward F. Chang · Stefan O. Ciurea · Jason B. Cross · Barbara Czako · Angela K. Deem · Naval Daver · John F. de Groot · Jian Wen Dong · Ningping Feng · Guang Gao · Mary Geck Do · Jennifer Greer · Virginia Giuliani · Jing Han · Lina Han · Verlene Henry · Judy Hirst · Sha Huang · Yongying Jiang · Zhijun Kang · Tin Khor · Sergej Konoplev · Yu Hsi Lin · Gang Liu · Alessia Lodi · Timothy Lofton · Helen Ma · Mikhila Mahendra · Polina Matre · Robert A. Mullinax · Michael Peoples · Alessia Petrocchi · Jaime Rodriguez-Canale · Riccardo Serreli · Thomas Shi · Melinda Smith · Yoko Tabe · Yoko Tabe · Jay Theroff · Stefano Tiziani · Quanyun Xu · Qi Zhang · Florian L. Muller · Ronald A. DePinho · Carlo Toniatti · Giulio Draetta · Timothy P. Heffernan · Marina Konopleva · Philip Jones · M. Emilia Di Francesco · Joseph R. Marszalek · Joseph R. Marszalek
An inhibitor of oxidative phosphorylation exploits cancer vulnerability Daniel S. Hsia · Steven B. Heymsfield · Steven B. Heymsfield
Reducing diabetes risk at an early age Ana Janic · Ana Janic · Liz J. Valente · Liz J. Valente · Liz J. Valente · Matthew J. Wakefield · Matthew J. Wakefield · Leon Di Stefano · Liz Milla · Liz Milla · Stephen Wilcox · Stephen Wilcox · Haoyu Yang · Haoyu Yang · Haoyu Yang · Lin Tai · Cassandra J. Vandenberg · Cassandra J. Vandenberg · Andrew J. Kueh · Andrew J. Kueh · Shinsuke Mizutani · Shinsuke Mizutani · Margs S. Brennan · Margs S. Brennan · Robyn L. Schenk · Robyn L. Schenk · Lisa Lindqvist · Lisa Lindqvist · Anthony T. Papenfuss · Anthony T. Papenfuss · Anthony T. Papenfuss · Liam O’Connor · Liam O’Connor · Andreas Strasser · Andreas Strasser · Marco J. Herold · Marco J. Herold · Marco J. Herold
DNA repair processes are critical mediators of p53-dependent tumor suppression Christina Yingxian Chen · Matthew A. Caporizzo · Kenneth C Bedi · Alexia Vite · Alexey I. Bogush · Patrick Robison · Julie Heffler · Alex K. Salomon · Neil A. Kelly · Apoorva Babu · Michael P. Morley · Kenneth B. Margulies · Benjamin L. Prosser · Benjamin L. Prosser
Targeting the cancer mutanome of breast cancer Russell A. Miller · Russell A. Miller · Yuji Shi · Wenyun Lu · David A. Pirman · Aditi Jatkar · Matthew Blatnik · Hong Wu · César Cárdenas · Min Wan · J. Kevin Foskett · Junyoung O. Park · Yiyi Zhang · William L. Holland · Joshua D. Rabinowitz · Morris J. Birnbaum · Morris J. Birnbaum · Morris J. Birnbaum
Targeting wild-type KRAS -amplified gastroesophageal cancer through combined MEK and SHP2 inhibition Radvanyi Lg · Radvanyi Lg
The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia Gabrielle S. Wong · Gabrielle S. Wong · Jin Zhou · Jie Bin Liu · Zhong Wu · Xinsen Xu · Tianxia Li · David Xu · Steven E. Schumacher · Jens Puschhof · James McFarland · James McFarland · Charles Zou · Austin M. Dulak · Les Henderson · Peng Xu · Emily O’Day · Rachel Rendak · Wei-Li Liao · Fabiola Cecchi · Todd Hembrough · Sarit Schwartz · Christopher Szeto · Anil K. Rustgi · Kwok-Kin Wong · J. Alan Diehl · Karin Jensen · Francesco Graziano · Annamaria Ruzzo · Shaunt Fereshetian · Philipp Mertins · Philipp Mertins · Steven A. Carr · Rameen Beroukhim · Kenichi Nakamura · Eiji Oki · Masayuki Watanabe · Masayuki Watanabe · Hideo Baba · Yu Imamura · Yu Imamura · Daniel V.T. Catenacci · Adam J. Bass · Adam J. Bass
SHP2 is required for growth of KRAS -mutant non-small-cell lung cancer in vivo Renée Beekman · Vicente Chapaprieta · Nuria Russiñol · Roser Vilarrasa-Blasi · Núria Verdaguer-Dot · Joost H.A. Martens · Martí Duran-Ferrer · Marta Kulis · François Serra · Biola M. Javierre · Steven W. Wingett · Guillem Clot · Ana C. Queirós · Giancarlo Castellano · Julie Blanc · Marta Gut · Angelika Merkel · Simon Heath · Anna Vlasova · Sebastian Ullrich · Emilio Palumbo · Anna Enjuanes · David Martín-García · Sílvia Beà · Magda Pinyol · Marta Aymerich · Romina Royo · Montserrat Puiggròs · David Torrents · Avik Datta · Ernesto Lowy · Myrto Kostadima · Maša Roller · Laura Clarke · Paul Flicek · Xabier Agirre · Xabier Agirre · Felipe Prosper · Felipe Prosper · Tycho Baumann · Julio Delgado · Armando López-Guillermo · Peter Fraser · Peter Fraser · Marie-Laure Yaspo · Roderic Guigó · Reiner Siebert · Marc A. Marti-Renom · Xose S. Puente · Xose S. Puente · Carlos López-Otín · Carlos López-Otín · Ivo Gut · Hendrik G. Stunnenberg · Elias Campo · José I. Martín-Subero · José I. Martín-Subero
Targeting G-quadruplex DNA as cognitive function therapy for ATR-X syndrome Sara Mainardi · Antonio Mulero-Sánchez · Anirudh Prahallad · Anirudh Prahallad · Giovanni Germano · Astrid Bosma · Paul Krimpenfort · Cor Lieftink · Jeffrey D. Steinberg · Niels de Wit · Samuel Gonçalves-Ribeiro · Ernest Nadal · Alberto Bardelli · Alberto Villanueva · René Bernards · René Bernards
An immune-beige adipocyte communication via nicotinic acetylcholine receptor signaling Norifumi Shioda · Yasushi Yabuki · Kouya Yamaguchi · Misaki Onozato · Yue Li · Kenji Kurosawa · Hideyuki Tanabe · Nobuhiko Okamoto · Takumi Era · Hiroshi Sugiyama · Takahito Wada · Kohji Fukunaga · Kohji Fukunaga
Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells Heejin Jun · Hui Yu · Jianke Gong · Jianke Gong · Juan Jiang · Juan Jiang · Xiaona Qiao · Xiaona Qiao · Eric Perkey · Dong il Kim · Margo P. Emont · Alexander G. Zestos · Alexander G. Zestos · Jung Sun Cho · Jianfeng Liu · Robert T. Kennedy · Ivan Maillard · X.Z. Shawn Xu · Jun Wu · Jun Wu
Modeling cytokine release syndrome Margherita Norelli · Barbara Camisa · Giulia Barbiera · Laura Falcone · Ayurzana Purevdorj · Marco Genua · Francesca Sanvito · Maurilio Ponzoni · Claudio Doglioni · Patrizia Cristofori · Catia Traversari · Claudio Bordignon · Claudio Bordignon · Fabio Ciceri · Renato Ostuni · Chiara Bonini · Monica Casucci · Attilio Bondanza · Attilio Bondanza
Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy Sanyal Anwesha · Mailliard Robbie B · Rinaldo Charles R · Ratner Deena · Ding Ming · Chen Yue · Venkatachari Narasimhan J · Gupta Phalguni · Zerbato Jennifer M · Giacobbi Nicholas S · Sluis‐Cremer Nicolas · Patterson Bruce K · Chargin Amanda · Chargin Amanda
The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space Garre Juan Mauricio · Yang Guang · Silva Hernandez Moura · Lafaille Juan J · Lafaille Juan J
Targeting skeletal endothelium to ameliorate bone loss Lu Wang · Zibo Zhao · Patrick A. Ozark · Damiano Fantini · Stacy A. Marshall · Emily J. Rendleman · Kira A. Cozzolino · Nundia Louis · Xingyao He · Marc A. Morgan · Yoh Hei Takahashi · Clayton K. Collings · Edwin R. Smith · Panagiotis Ntziachristos · Jeffrey N. Savas · Lihua Zou · Rintaro Hashizume · Joshua J. Meeks · Ali Shilatifard · Ali Shilatifard
HIV vaccine candidate activation of hypoxia and the inflammasome in CD14 + monocytes is associated with a decreased risk of SIV mac251 acquisition Ren Xu · Alisha Yallowitz · An Qin · Zhuhao Wu · Dong Yeon Shin · Jung-Min Kim · Shawon Debnath · Gang Ji · Gang Ji · Mathias Bostrom · Xu Yang · Chao Zhang · Han Dong · Han Dong · Pouneh Kermani · Sarfaraz Lalani · Na Li · Yifang Liu · Michael G. Poulos · Amanda Wach · Yi Zhang · Kazuki Inoue · Kazuki Inoue · Annarita Di Lorenzo · Baohong Zhao · Baohong Zhao · Jason M. Butler · Jae-Hyuck Shim · Laurie H. Glimcher · Laurie H. Glimcher · Matthew B. Greenblatt · Matthew B. Greenblatt
CAR T cell-induced cytokine release syndrome is mediated by macrophages and abated by IL-1 blockade Monica Vaccari · Slim Fourati · Shari N. Gordon · Dallas R. Brown · Massimilano Bissa · Luca Schifanella · Isabela Silva de Castro · Melvin N. Doster · Veronica Galli · Maria Omsland · Dai Fujikawa · Giacomo Gorini · Namal P.M. Liyanage · Hung V. Trinh · Hung V. Trinh · Katherine McKinnon · Kathryn E. Foulds · Brandon F. Keele · Mario Roederer · Richard A. Koup · Xiaoying Shen · Georgia D. Tomaras · Marcus P. Wong · Karissa J. Munoz · Johannes S. Gach · Donald N. Forthal · David C. Montefiori · David Venzon · Barbara K. Felber · Margherita Rosati · George N. Pavlakis · Mangala Rao · Rafick-Pierre Sekaly · Genoveffa Franchini · Genoveffa Franchini
Convergence of placenta biology and genetic risk for schizophrenia Theodoros Giavridis · Sjoukje J. C. van der Stegen · Justin Eyquem · Mohamad Hamieh · Alessandra Piersigilli · Michel Sadelain · Michel Sadelain
Mutant KRAS -driven cancers depend on PTPN11 /SHP2 phosphatase Gianluca Ursini · Gianluca Ursini · Giovanna Punzi · Qiang Chen · Stefano Marenco · Joshua F. Robinson · Annamaria Porcelli · Emily G. Hamilton · Marina Mitjans · Giancarlo Maddalena · Martin Begemann · Jan Seidel · Hidenaga Yanamori · Andrew E. Jaffe · Karen Faith Berman · Michael F. Egan · Richard E. Straub · Carlo Colantuoni · Carlo Colantuoni · Giuseppe Blasi · Ryota Hashimoto · Dan Rujescu · Hannelore Ehrenreich · Alessandro Bertolino · Daniel R. Weinberger · Daniel R. Weinberger
The best Cas scenario Dietrich A. Ruess · Dietrich A. Ruess · Guus J.J.E. Heynen · Katrin J. Ciecielski · Jiaoyu Ai · Alexandra Berninger · Derya Kabacaoglu · Kivanc Görgülü · Zahra Dantes · Sonja Wörmann · Kalliope N. Diakopoulos · Angeliki F. Karpathaki · Marlena Kowalska · Ezgi Kaya-Aksoy · Liang Song · Eveline A. Zeeuw van der Laan · María P. López-Alberca · Marc Nazaré · Maximilian Reichert · Dieter Saur · Mert Erkan · Ulrich T. Hopt · Bruno Sainz · Walter Birchmeier · Roland M. Schmid · Marina Lesina · Hana Algül · Hana Algül
Elevated prenatal anti-Müllerian hormone reprograms the fetus and induces polycystic ovary syndrome in adulthood Peter Andrey Smith · Peter Andrey Smith
Animals on the verge: What different species can teach us about human puberty Leila Dardaei · Hui Qin Wang · Manrose Singh · Paul Fordjour · Katherine X Shaw · Satoshi Yoda · Grainne Kerr · Kristine Yu · Jinsheng Liang · Yichen Cao · Yan Chen · Michael S. Lawrence · Adam Langenbucher · Justin F. Gainor · Luc Friboulet · Ibiayi Dagogo-Jack · David T. Myers · Emma Labrot · David A. Ruddy · Melissa Parks · Dana Lee · Richard H. DiCecca · Susan E. Moody · Huai-Xiang Hao · Morvarid Mohseni · Matthew J. LaMarche · Juliet Williams · Keith Hoffmaster · Giordano Caponigro · Alice T. Shaw · Aaron N. Hata · Cyril H. Benes · Fang Li · Jeffrey A. Engelman · Jeffrey A. Engelman
High-dimensional single-cell analysis predicts response to anti-PD-1 immunotherapy Enrico Velardi · Jennifer J. Tsai · Stefan Radtke · Kirsten Cooper · Kimon V. Argyropoulos · Shieh Jae-Hung · Lauren F. Young · Amina Lazrak · Odette M. Smith · Sophie Lieberman · Fabiana M Kreines · Yusuke Shono · Tobias Wertheimer · Robert R. Jenq · Alan M. Hanash · Prema Narayan · Zhenmin Lei · Malcolm A. S. Moore · Hans-Peter Kiem · Marcel R.M. van den Brink · Jarrod A. Dudakov · Jarrod A. Dudakov
Modeling tumors and their T cell killers Michael K. Skinner · Michael K. Skinner
Identifying atrial fibrillation Lesley Hoyles · José-Manuel Fernández-Real · Massimo Federici · Matteo Serino · Matteo Serino · James Abbott · Julie Charpentier · Julie Charpentier · Christophe Heymes · Christophe Heymes · Jèssica Latorre Luque · Elodie Anthony · Richard H. Barton · Julien Chilloux · Antonis Myridakis · Laura Martinez-Gili · José María Moreno-Navarrete · Fadila Benhamed · Vincent Azalbert · Vincent Azalbert · Vincent Blasco-Baque · Vincent Blasco-Baque · Josep Puig · Wifredo Ricart · Christopher Tomlinson · Mark Woodbridge · Marina Cardellini · Francesca Davato · Iris Cardolini · Ottavia Porzio · Ottavia Porzio · Paolo Gentileschi · Frédéric Lopez · Frédéric Lopez · Fabienne Foufelle · Sarah Butcher · Elaine Holmes · Jeremy K. Nicholson · C. Postic · Rémy Burcelin · Rémy Burcelin · Marc-Emmanuel Dumas · Marc-Emmanuel Dumas
BRAF somatic mutation contributes to intrinsic epileptogenicity in pediatric brain tumors Michael A. Schwemmer · Nicholas D. Skomrock · Per B. Sederberg · Jordyn E. Ting · Gaurav Sharma · Marcia Bockbrader · David A. Friedenberg · David A. Friedenberg
Meeting brain–computer interface user performance expectations using a deep neural network decoding framework Francesca Zanconato · Giusy Battilana · Mattia Forcato · Letizia Filippi · Luca Azzolin · Andrea Manfrin · Erika Quaranta · Daniele Di Biagio · Gianluca Sigismondo · Vincenza Guzzardo · Pascale Lejeune · Bernard Haendler · Jeroen Krijgsveld · Matteo Fassan · Silvio Bicciato · Michelangelo Cordenonsi · Stefano Piccolo · Stefano Piccolo
Transcriptional addiction in cancer cells is mediated by YAP/TAZ through BRD4 Sandra R. Bacman · Johanna H.K. Kauppila · Claudia V. Pereira · Nadee Nissanka · Maria Miranda · Milena Pinto · Sion L. Williams · Nils-Göran Larsson · James B. Stewart · Carlos T. Moraes · Carlos T. Moraes
MitoTALEN reduces mutant mtDNA load and restores tRNA Ala levels in a mouse model of heteroplasmic mtDNA mutation Payam A. Gammage · Carlo Viscomi · Marie-Lune Simard · Ana S.H. Costa · Edoardo Gaude · Christopher A. Powell · Lindsey Van Haute · Beverly J. McCann · Pedro Rebelo-Guiomar · Pedro Rebelo-Guiomar · Raffaele Cerutti · Lei Zhang · Edward J. Rebar · Massimo Zeviani · Christian Frezza · James B. Stewart · Michal Minczuk · Michal Minczuk
Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo Megan L. Gill · Peter J. Grahn · Jonathan S. Calvert · Margaux B. Linde · Igor A. Lavrov · Igor A. Lavrov · Jeffrey A. Strommen · Lisa A. Beck · Dimitry G. Sayenko · Meegan G. Van Straaten · Dina I. Drubach · Daniel D. Veith · Andrew R. Thoreson · Cesar Lopez · Yury Gerasimenko · Yury Gerasimenko · V. Reggie Edgerton · Kendall H. Lee · Kristin D. Zhao · Kristin D. Zhao
Neuromodulation of lumbosacral spinal networks enables independent stepping after complete paraplegia Hannah Stower · Hannah Stower
Early immune development Hannah Stower · Hannah Stower
Live bacterial therapies for metabolic disease Yotam Bar-On · Henning Gruell · Till Schoofs · Joy Pai · Lilian Nogueira · Allison L. Butler · Katrina Millard · Clara Lehmann · Isabelle Suárez · Thiago Y. Oliveira · Theodora Karagounis · Yehuda Z. Cohen · Christoph Wyen · Stefan Scholten · Lisa Handl · Shiraz Belblidia · Juan P. Dizon · Jörg J. Vehreschild · Maggi Witmer-Pack · Irina Shimeliovich · Kanika Jain · Kerstin Fiddike · Kelly E. Seaton · Nicole L. Yates · Jill Horowitz · Roy M. Gulick · Nico Pfeifer · Georgia D. Tomaras · Michael S. Seaman · Gerd Fätkenheuer · Marina Caskey · Florian Klein · Michel C. Nussenzweig · Michel C. Nussenzweig · Michel C. Nussenzweig
Safety and antiviral activity of combination HIV-1 broadly neutralizing antibodies in viremic individuals Elena Orlando · Xia Han · Catherine Tribouley · Patricia A. Wood · Rebecca J. Leary · Markus Riester · John E. Levine · Muna Qayed · Stephan A. Grupp · Michael Boyer · Barbara De Moerloose · Eneida R. Nemecek · Henrique Bittencourt · Hidefumi Hiramatsu · Jochen Buechner · Stella M. Davies · Michael R. Verneris · Kevin Nguyen · Jennifer Brogdon · Hans Bitter · Michael Morrissey · Piotr Pierog · Serafino Pantano · Jeffrey A. Engelman · Wendy Winckler · Wendy Winckler
Genetic mechanisms of target antigen loss in CAR19 therapy of acute lymphoblastic leukemia Kanmin Xue · Jasleen K. Jolly · Alun R. Barnard · Anna Rudenko · Anna Paola Salvetti · Maria I. Patrício · Thomas L. Edwards · Markus Groppe · Harry O. Orlans · Tanya Tolmachova · Graeme C.M. Black · Andrew R. Webster · Andrew R. Webster · Andrew J. Lotery · Graham E. Holder · Graham E. Holder · Graham E. Holder · Susan M. Downes · Miguel C. Seabra · Miguel C. Seabra · Robert E. MacLaren · Robert E. MacLaren · Robert E. MacLaren
Beneficial effects on vision in patients undergoing retinal gene therapy for choroideremia Hannah Stower · Hannah Stower
Gene editing for Duchenne muscular dystrophy Hannah Stower · Hannah Stower
Interpreting the unknown Sarwish Rafiq · Renier J. Brentjens · Renier J. Brentjens · Renier J. Brentjens
Tumors evading CARs—the chase is on Nora D. Volkow · Ruben Baler · Ruben Baler
A prescription for better opioid prescribing Serena Scala · Luca Basso-Ricci · Francesca Dionisio · Danilo Pellin · Stefania Giannelli · Federica Andrea Salerio · Lorena Leonardelli · Maria Pia Cicalese · Francesca Ferrua · Alessandro Aiuti · Luca Biasco · Luca Biasco
Dynamics of genetically engineered hematopoietic stem and progenitor cells after autologous transplantation in humans Marco Ruella · Jun Xu · David M. Barrett · Joseph A. Fraietta · Tyler J. Reich · David E Ambrose · Michael Klichinsky · Olga Shestova · Prachi R. Patel · Irina Kulikovskaya · Farzana Nazimuddin · Vijay Bhoj · Elena Orlando · Terry J. Fry · Hans Bitter · Shannon L. Maude · Bruce L. Levine · Christopher L. Nobles · Frederic D. Bushman · Regina M. Young · John Scholler · Saar Gill · Carl H. June · Stephan A. Grupp · Simon F. Lacey · J. Joseph Melenhorst · J. Joseph Melenhorst
Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell Lintao Zhao · Ran He · Haixia Long · Bo Guo · Qingzhu Jia · Diyuan Qin · Si-Qi Liu · Zhongyu Wang · Tong Xiang · Jue Zhang · Yulong Tan · Jiani Huang · Junying Chen · Fang Wang · Minglu Xiao · Jianbao Gao · Xinxin Yang · Hao Zeng · Xinxin Wang · Chunyan Hu · Peter B. Alexander · Alistair L. J. Symonds · Jia Yu · Yisong Y. Wan · Qi-Jing Li · Lilin Ye · Bo Zhu · Bo Zhu
Author Correction: Regional variation limits applications of healthy gut microbiome reference ranges and disease models Hyun Yong Koh · Se Hoon Kim · Jaeson Jang · H.J. Kim · Sungwook Han · Jae Seok Lim · Geurim Son · Junjeong Choi · Byung Ouk Park · Won Do Heo · Jinju Han · Hyunjoo Lee · Daeyoup Lee · Hoon-Chul Kang · Minho Shong · Se-Bum Paik · Dong Seok Kim · Jeong Ho Lee · Jeong Ho Lee
Bringing polygenic risk scores to the clinic Yan He · Wei Wu · Wei Wu · Hui-Min Zheng · Pan Li · Daniel McDonald · Hua-Fang Sheng · Mu-Xuan Chen · Zi-Hui Chen · Gui-Yuan Ji · Zhong-Dai-Xi Zheng · Prabhakar Mujagond · Xiao-Jiao Chen · Zu-Hua Rong · Peng Chen · Li-Yi Lyu · Xian Wang · Chong-Bin Wu · Nan Yu · Yanjun Xu · Jia Yin · Jeroen Raes · Jeroen Raes · Rob Knight · Wenjun Ma · Hong-Wei Zhou · Hong-Wei Zhou
Right data for right patient—a precisionFDA NCI–CPTAC Multi-omics Mislabeling Challenge Hannah Stower · Hannah Stower
Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase Nicole Wetsman · Nicole Wetsman
Author Correction: Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring Hannah Stower · Hannah Stower
Predicting preterm birth Rongya Tao · Caixia Wang · Oliver Stöhr · Wei Qiu · Yue Hu · Ji Miao · X. Charlie Dong · Sining Leng · Margaret A. Stefater · Nicholas Stylopoulos · Lin Lin · Kyle D. Copps · Morris F. White · Morris F. White
Publisher Correction: Inactivating hepatic follistatin alleviates hyperglycemia Hannah Stower · Hannah Stower
Cell therapy for spinal cord injury Christopher S. Probert · Christina Curtis · Christina Curtis
A role for chromatin regulatory dynamics in breast cancer evolution Amanda B. Keener · Amanda B. Keener
Just the messenger Peter Savas · Peter Savas · Balaji Virassamy · Chengzhong Ye · Chengzhong Ye · Agus Salim · Christopher P. Mintoff · Franco Caramia · Roberto Salgado · David J. Byrne · Zhi L. Teo · Zhi L. Teo · Sathana Dushyanthen · Ann Byrne · Lironne Wein · Stephen J. Luen · Catherine Poliness · Sophie S. Nightingale · Anita S. Skandarajah · Anita S. Skandarajah · David E. Gyorki · Chantel M. Thornton · Paul A. Beavis · Paul A. Beavis · Stephen B. Fox · Stephen B. Fox · Phillip K. Darcy · Phillip K. Darcy · Terence P. Speed · Laura K. Mackay · Paul Neeson · Paul Neeson · Sherene Loi · Sherene Loi · Sherene Loi
Publisher Correction: Single-cell profiling of breast cancer T cells reveals a tissue-resident memory subset associated with improved prognosis Roger W. Hunter · Roger W. Hunter · Curtis C. Hughey · Louise Lantier · Elias I. Sundelin · Mark Peggie · Elton Zeqiraj · Elton Zeqiraj · Frank Sicheri · Frank Sicheri · Niels Jessen · David H. Wasserman · Kei Sakamoto · Kei Sakamoto
When the golden years turn blue Margaret E. Ackerman · Jishnu Das · Srivamshi Pittala · Thomas A. Broge · Caitlyn Linde · Todd J. Suscovich · Eric P. Brown · Todd Bradley · Harini Natarajan · Shu Lin · Jessica K. Sassic · Sean O’Keefe · Nickita Mehta · Derrick Goodman · Magdalena Sips · Joshua A. Weiner · Georgia D. Tomaras · Barton F. Haynes · Douglas A. Lauffenburger · Chris Bailey-Kellogg · Mario Roederer · Galit Alter · Galit Alter
An option for treatment of multidrug-resistant HIV Emily S. Boja · Živana Težak · Bing Zhang · Pei Wang · Elaine Johanson · Denise Hinton · Henry Rodriguez · Henry Rodriguez
Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV Charles J. Lynch · Conor Liston · Conor Liston
New machine-learning technologies for computer-aided diagnosis Heerajnarain Bulluck · Derek J. Hausenloy · Derek J. Hausenloy
Modulating NAD+ metabolism to prevent acute kidney injury Hannah Stower · Hannah Stower
Revising salt consumption Hannah Stower · Hannah Stower
Restoring sight with native cell reprogramming Shruti Naik · Shruti Naik
Wound, heal thyself Hannah Stower · Hannah Stower
Preconception cold–induced epigenetic inheritance Hannah Stower · Hannah Stower
Late-stage tumors induce anemia and immunosuppressive extramedullary erythroid progenitor cells Guido Veit · Haijin Xu · Elise Dreano · Radu G. Avramescu · Miklos Bagdany · Lenore K. Beitel · Ariel Roldan · Mark A. Hancock · Cecilia Lay · Wei Li · Katelin Morin · Sandra Gao · Puiying A. Mak · Edward Ainscow · Anthony P. Orth · Peter McNamara · Aleksander Edelman · Saul Frenkiel · Elias Matouk · I. Sermet-Gaudelus · William G. Barnes · Gergely L. Lukacs · Gergely L. Lukacs
Structure-guided combination therapy to potently improve the function of mutant CFTRs Christopher A. Gaulke · Thomas J. Sharpton · Thomas J. Sharpton
The influence of ethnicity and geography on human gut microbiome composition Chengxiang Qiu · Shizheng Huang · Jihwan Park · YoSon Park · Yi-An Ko · Matthew J. Seasock · Joshua S. Bryer · Xiang-Xi Xu · Wen-Chao Song · Matthew Palmer · Jon Hill · Paolo Guarnieri · Julie Hawkins · Carine M. Boustany-Kari · Steven S. Pullen · Christopher D. Brown · Katalin Susztak · Katalin Susztak
Expanded skin virome in DOCK8-deficient patients Michael Cerezo · Ramdane Guemiri · Sabine Druillennec · Isabelle Girault · Hélène Malka-Mahieu · Shensi Shen · Delphine Allard · Sylvain Martineau · Caroline Welsch · Sandrine Agoussi · Charlène Estrada · Julien Adam · Cristina Libenciuc · E. Routier · Séverine Roy · Laurent Désaubry · Alexander M.M. Eggermont · Nahum Sonenberg · Jean-Yves Scoazec · Alain Eychène · Stéphan Vagner · Caroline Robert · Caroline Robert
High prevalence of Streptococcus pyogenes Cas9-reactive T cells within the adult human population Noam Auslander · Noam Auslander · Gao Zhang · Joo Sang Lee · Joo Sang Lee · Dennie T. Frederick · Benchun Miao · Tabea Moll · Tian Tian · Zhi Wei · Sanna Madan · Sanna Madan · Ryan J. Sullivan · Genevieve M. Boland · Keith T. Flaherty · Meenhard Herlyn · Eytan Ruppin · Eytan Ruppin · Eytan Ruppin
Publisher Correction: Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma Megan L. Gill · Peter J. Grahn · Jonathan S. Calvert · Margaux B. Linde · Igor A. Lavrov · Igor A. Lavrov · Jeffrey A. Strommen · Lisa A. Beck · Dimitry G. Sayenko · Dimitry G. Sayenko · Meegan G. Van Straaten · Dina I. Drubach · Daniel D. Veith · Andrew R. Thoreson · Cesar Lopez · Yury Gerasimenko · Yury Gerasimenko · V. Reggie Edgerton · Kendall H. Lee · Kristin D. Zhao · Kristin D. Zhao
Publisher Correction: Neuromodulation of lumbosacral spinal networks enables independent stepping after complete paraplegia Alison Farrell · Alison Farrell
A vaccine for tuberculosis Lisa Fish · Steven Zhang · Johnny X. Yu · Bruce Culbertson · Alicia Y. Zhou · Andrei Goga · Hani Goodarzi · Hani Goodarzi
Cancer cells exploit an orphan RNA to drive metastatic progression Michael Basson · Michael Basson
Personalized tracking of exposure to airborne organisms and chemicals Brett Benedetti · Brett Benedetti
Human skeletal stem cells identified Osnat Tirosh · Nisc Comparative Sequencing Program · Sean Conlan · Clay Deming · Shih-Queen Lee-Lin · Xin Huang · Helen C. Su · Alexandra F. Freeman · Julia A. Segre · Heidi H. Kong · Heidi H. Kong
Translational control of tumor immune escape via the eIF4F–STAT1–PD-L1 axis in melanoma James J. Morrow · Ian Bayles · Alister P.W. Funnell · Tyler E. Miller · Alina Saiakhova · Michael M. Lizardo · Cynthia F. Bartels · Maaike Y. Kapteijn · Stevephen Hung · Arnulfo Mendoza · Gursimran Dhillon · Daniel R. Chee · Jay Myers · Frederick Allen · Marco Gambarotti · Alberto Righi · Analisa DiFeo · Brian P. Rubin · Alex Y. Huang · Paul S. Meltzer · Lee J. Helman · Piero Picci · Henri H. Versteeg · John A. Stamatoyannopoulos · Chand Khanna · Peter C. Scacheri · Peter C. Scacheri
A biobank of patient-derived pediatric brain tumor models Matthieu Komorowski · Matthieu Komorowski · Leo Anthony Celi · Leo Anthony Celi · Omar Badawi · Omar Badawi · Omar Badawi · Anthony C. Gordon · A. Aldo Faisal · A. Aldo Faisal
Corrigendum: Positively selected enhancer elements endow osteosarcoma cells with metastatic competence Kate Gao · Kate Gao
Analyzing the drug overdose epidemic in the United States Silvia C. Formenti · Nils-Petter Rudqvist · Encouse B. Golden · Benjamin T. Cooper · Erik Wennerberg · Claire Lhuillier · Claire Vanpouille-Box · Kent Friedman · Lucas Ferrari de Andrade · Kai W. Wucherpfennig · Adriana Heguy · Naoko Imai · Sacha Gnjatic · Ryan Emerson · Xi Kathy Zhou · Tuo Zhang · Abraham Chachoua · Sandra Demaria · Sandra Demaria
Radiotherapy induces responses of lung cancer to CTLA-4 blockade Rodabe N. Amaria · Sangeetha M. Reddy · Hussein Abdul-Hassan Tawbi · Michael A. Davies · Merrick I. Ross · Isabella C. Glitza · Janice N. Cormier · Carol M. Lewis · Wen-Jen Hwu · Ehab Y. Hanna · Adi Diab · Michael K. Wong · Richard E. Royal · Neil D. Gross · Randal S. Weber · Stephen Y. Lai · Richard A. Ehlers · Jorge Blando · Denái R. Milton · Scott E. Woodman · Robin Kageyama · Daniel K. Wells · Patrick Hwu · Sapna Pradyuman Patel · Anthony Lucci · Amy C. Hessel · Jeffrey E. Lee · Jeffrey E. Gershenwald · Lauren Simpson · Elizabeth Burton · Liberty Posada · Lauren E. Haydu · Linghua Wang · Shaojun Zhang · Alexander J. Lazar · Courtney W. Hudgens · Vancheswaran Gopalakrishnan · Alexandre Reuben · Miles C. Andrews · Christine N. Spencer · Victor G. Prieto · Padmanee Sharma · James P. Allison · Michael T. Tetzlaff · Jennifer A. Wargo · Jennifer A. Wargo
Publisher Correction: Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma Rui Chen · Lin Xia · Kailing Tu · Meixue Duan · Kimberly R. Kukurba · Jennifer Li-Pook-Than · Dan Xie · Michael Snyder · Michael Snyder
Longitudinal personal DNA methylome dynamics in a human with a chronic condition Aimee M. Baumann-Dudenhoeffer · Alaric W. D’Souza · Phillip I. Tarr · Barbara B. Warner · Gautam Dantas · Gautam Dantas
Infant diet and maternal gestational weight gain predict early metabolic maturation of gut microbiomes Jean M. Mulcahy Levy · Martin McMahon · Martin McMahon
Linking brain tumors and epileptic seizures Lulu Sun · Cen Xie · Guang Wang · Yue Wu · Qing Wu · Xuemei Wang · Jia Liu · Yangyang Deng · Jialin Xia · Bo Chen · Songyang Zhang · Chuyu Yun · Guan Lian · Xiujuan Zhang · Heng Zhang · William H. Bisson · Jingmin Shi · Xiaoxia Gao · Pupu Ge · Cuihua Liu · Kristopher W. Krausz · Robert G. Nichols · Jingwei Cai · Bipin Rimal · Andrew D. Patterson · Xian Wang · Frank J. Gonzalez · Changtao Jiang · Changtao Jiang
The Artificial Intelligence Clinician learns optimal treatment strategies for sepsis in intensive care Dimitrios Laurin Wagner · Leila Amini · Desiree Jacqueline Wendering · Lisa-Marie Burkhardt · Levent Akyüz · Petra Reinke · Hans-Dieter Volk · Michael Schmueck-Henneresse · Michael Schmueck-Henneresse
Verapamil and beta cell function in adults with recent-onset type 1 diabetes Sebastian Brabetz · Sebastian Brabetz · Sarah Leary · Sarah Leary · Susanne Gröbner · Madison W. Nakamoto · Huriye Şeker-Cin · Emily J. Girard · Bonnie Cole · Andrew D. Strand · Karina Bloom · Volker Hovestadt · Volker Hovestadt · Volker Hovestadt · Norman Mack · Fiona Pakiam · Benjamin Schwalm · Andrey Korshunov · Andrey Korshunov · Gnana Prakash Balasubramanian · Paul A. Northcott · Paul A. Northcott · Kyle Pedro · Joyoti Dey · Stacey Hansen · Sally Ditzler · Peter Lichter · Lukas Chavez · Lukas Chavez · David T. W. Jones · Jan Koster · Stefan M. Pfister · Stefan M. Pfister · Marcel Kool · James M. Olson · James M. Olson · James M. Olson
Renal compartment–specific genetic variation analyses identify new pathways in chronic kidney disease Hannah Stower · Hannah Stower
Author Correction: MitoTALEN reduces mutant mtDNA load and restores tRNA Ala levels in a mouse model of heteroplasmic mtDNA mutation Jahyun Koo · Matthew R. MacEwan · Seung-Kyun Kang · Sang Min Won · Manu Stephen · Paul Gamble · Zhaoqian Xie · Ying Yan · Yu-Yu Chen · Jiho Shin · Nathan K Birenbaum · Sangjin Chung · Sung Bong Kim · Jawad M. Khalifeh · Daniel V. Harburg · Kelsey Bean · Michael Paskett · Jeonghyun Kim · Zohny Zohny · Seung Min Lee · Ruoyao Zhang · Kaijing Luo · Bowen Ji · Anthony Banks · Anthony Banks · Hyuck Mo Lee · Younggang Huang · Wilson Z. Ray · John A. Rogers · John A. Rogers
Towards poliovirus eradication Rodabe N. Amaria · Sangeetha M. Reddy · Hussein Abdul-Hassan Tawbi · Michael A. Davies · Merrick I. Ross · Isabella C. Glitza · Janice N. Cormier · Carol M. Lewis · Wen-Jen Hwu · Ehab Y. Hanna · Adi Diab · Michael K. Wong · Richard E. Royal · Neil D. Gross · Randal S. Weber · Stephen Y. Lai · Richard A. Ehlers · Jorge Blando · Denái R. Milton · Scott E. Woodman · Robin Kageyama · Daniel K. Wells · Patrick Hwu · Sapna Pradyuman Patel · Anthony Lucci · Amy C. Hessel · Jeffrey E. Lee · Jeffrey E. Gershenwald · Lauren Simpson · Elizabeth Burton · Liberty Posada · Lauren E. Haydu · Linghua Wang · Shaojun Zhang · Alexander J. Lazar · Courtney W. Hudgens · Vancheswaran Gopalakrishnan · Alexandre Reuben · Miles C. Andrews · Christine N. Spencer · Victor G. Prieto · Padmanee Sharma · James P. Allison · Michael T. Tetzlaff · Jennifer A. Wargo · Jennifer A. Wargo
Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma Christian U. Blank · Elisa A. Rozeman · Lorenzo Fanchi · Karolina Sikorska · Bart A. van de Wiel · Pia Kvistborg · Oscar Krijgsman · Marlous van den Braber · Daisy Philips · Annegien Broeks · Johannes V. Van Thienen · Henk Mallo · Sandra Adriaansz · Sylvia ter Meulen · Loes M. Pronk · Lindsay G. Grijpink-Ongering · Annemarie Bruining · Rachel M. Gittelman · Sarah Warren · Harm van Tinteren · Daniel S. Peeper · John B. A. G. Haanen · Alexander C.J. van Akkooi · Ton N. M. Schumacher · Ton N. M. Schumacher
Neoadjuvant versus adjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma Huiyun Seo · Jin-Soo Kim · Jin-Soo Kim
Towards therapeutic base editing Lukas Villiger · Hiu Man Grisch-Chan · Helen Lindsay · Helen Lindsay · Femke Ringnalda · Chiara B. Pogliano · Gabriella Allegri · Johannes Häberle · Joao Matos · Mark D. Robinson · Mark D. Robinson · Beat Thöny · Gerald Schwank · Gerald Schwank
Treatment of a metabolic liver disease by in vivo genome base editing in adult mice Shraddha Chakradhar · Shraddha Chakradhar
Lost in the maze Colin Barras · Colin Barras
Going to waste Sandra R. Bacman · Johanna H.K. Kauppila · Claudia V. Pereira · Nadee Nissanka · Maria Miranda · Milena Pinto · Sion L. Williams · Nils-Göran Larsson · James B. Stewart · Carlos T. Moraes · Carlos T. Moraes
Wireless bioresorbable electronic system enables sustained nonpharmacological neuroregenerative therapy Avery C. Rossidis · John D. Stratigis · Alexandra C. Chadwick · Heather A. Hartman · Nicholas J. Ahn · Haiying Li · Kshitiz Singh · Barbara E. Coons · Li Li · Wenjian Lv · Philip W. Zoltick · Deepthi Alapati · William Zacharias · Rajan Jain · Edward E. Morrisey · Kiran Musunuru · William H. Peranteau · William H. Peranteau
Author Correction: Nociceptor sensory neurons suppress neutrophil and γδ T cell responses in bacterial lung infections and lethal pneumonia Fernando Ovalle · Tiffany Grimes · Guanlan Xu · Anish J. Patel · Truman Grayson · Lance Thielen · Peng Li · Anath Shalev · Anath Shalev
In utero CRISPR-mediated therapeutic editing of metabolic genes Lei Jiang · Pedro Berraondo · Pedro Berraondo · Daniel Jericó · Lin Tung Guey · Ana Sampedro · Andrea Frassetto · Kerry E. Benenato · Kristine Burke · Eva Santamaría · Eva Santamaría · Manuel Alegre · Álvaro Pejenaute · Mayur Kalariya · William Butcher · Ji-Sun Park · Xuling Zhu · Staci Sabnis · E. Sathyajith Kumarasinghe · Timothy Salerno · Matthew Kenney · Christine M. Lukacs · Matías A. Avila · Matías A. Avila · Paolo Martini · Antonio Fontanellas · Antonio Fontanellas · Antonio Fontanellas
Systemic messenger RNA as an etiological treatment for acute intermittent porphyria David F. McDermott · Mahrukh Huseni · Michael B. Atkins · Robert J. Motzer · Brian I. Rini · Bernard Escudier · Lawrence Fong · Richard W. Joseph · Sumanta K. Pal · James Reeves · Mario Sznol · John D. Hainsworth · W.Kimryn Rathmell · Walter M. Stadler · Thomas E. Hutson · Martin Gore · Alain Ravaud · Sergio Bracarda · Cristina Suárez · Riccardo Danielli · Viktor Gruenwald · Toni K. Choueiri · Dorothee Nickles · Suchit Jhunjhunwala · Elisabeth Piault-Louis · Alpa Thobhani · Jiaheng Qiu · Daniel S. Chen · Priti Hegde · Christina Schiff · Gregg Fine · Thomas Powles · Thomas Powles
Publisher Correction: Clinical activity and molecular correlates of response to atezolizumab alone or in combination with bevacizumab versus sunitinib in renal cell carcinoma Marjorie Z. Imperial · Payam Nahid · Patrick P. J. Phillips · Geraint Davies · Katherine Fielding · Debra Hanna · David Hermann · Robert S. Wallis · John L. Johnson · Christian Lienhardt · Rada M. Savic · Rada M. Savic
A Patient-Level Pooled Analysis of Treatment Shortening Regimens for Drug-Susceptible Pulmonary Tuberculosis Jorge Sepulcre · Michel J. Grothe · Federico d’Oleire Uquillas · Laura Ortiz-Terán · Ibai Diez · Hyun-Sik Yang · Heidi I.L. Jacobs · Bernard Hanseeuw · Quanzheng Li · Georges El-Fakhri · Reisa A. Sperling · Keith Johnson · Keith Johnson
Neurogenetic contributions to amyloid beta and tau spreading in the human cortex Daniel B. Graham · Chengwei Luo · Chengwei Luo · Daniel J. O’Connell · Ariel Lefkovith · Eric M. Brown · Moran Yassour · M. Varma · Jennifer G. Abelin · Kara L. Conway · Guadalupe J. Jasso · Guadalupe J. Jasso · Caline G. Matar · Steven A. Carr · Ramnik J. Xavier · Ramnik J. Xavier
Antigen discovery and specification of immunodominance hierarchies for MHCII-restricted epitopes Daniel Engber · Daniel Engber
Author Correction: What models eat Pankaj Baral · Benjamin D. Umans · Lu Li · Antonia Wallrapp · Meghna Bist · Talia Kirschbaum · Yibing Wei · Yan Zhou · Vijay K. Kuchroo · Patrick R. Burkett · Bryan G. Yipp · Stephen D. Liberles · Isaac M. Chiu · Isaac M. Chiu
Publisher Correction: Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women Wenfei Sun · Hua Dong · Anton S. Becker · Dianne H. Dapito · Salvatore Modica · Gerald Grandl · Lennart Opitz · Lennart Opitz · Vissarion Efthymiou · Leon G. Straub · Gitalee Sarker · Miroslav Balaz · Lucia Balazova · Aliki Perdikari · Elke Kiehlmann · Sara Bacanovic · Caroline Zellweger · Daria Peleg-Raibstein · Pawel Pelczar · Wolf Reik · Wolf Reik · Irene A. Burger · Ferdinand von Meyenn · Ferdinand von Meyenn · Christian Wolfrum · Christian Wolfrum
Publisher Correction: Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring Wenfei Sun · Hua Dong · Anton S. Becker · Dianne H. Dapito · Salvatore Modica · Gerald Grandl · Lennart Opitz · Lennart Opitz · Vissarion Efthymiou · Leon G. Straub · Gitalee Sarker · Miroslav Balaz · Lucia Balazova · Aliki Perdikari · Elke Kiehlmann · Sara Bacanovic · Caroline Zellweger · Daria Peleg-Raibstein · Pawel Pelczar · Wolf Reik · Wolf Reik · Irene A. Burger · Ferdinand von Meyenn · Ferdinand von Meyenn · Christian Wolfrum · Christian Wolfrum
Beta cell preservation in patients with type 1 diabetes Freya R. Svedberg · Martin Guilliams · Martin Guilliams
A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite Pernilla Roswall · Pernilla Roswall · Matteo Bocci · Michael Bartoschek · Hong Li · Glen Kristiansen · Sara Jansson · Sophie Lehn · Jonas Sjölund · Steven Reid · Christer Larsson · Pontus Eriksson · Charlotte Anderberg · Eliane Cortez · Lao H. Saal · Christina Orsmark-Pietras · Eugenia Cordero · Bengt Kristian Haller · Jari Häkkinen · Ingrid J. G. Burvenich · Elgene Lim · Akira Orimo · Mattias Höglund · Lisa Rydén · Holger Moch · Andrew M. Scott · Ulf Eriksson · Kristian Pietras · Kristian Pietras
A previously undetected pathology of Zika virus infection Ming Xu · Ming Xu · Tamar Pirtskhalava · Joshua N. Farr · Bettina M. Weigand · Bettina M. Weigand · Allyson K. Palmer · Megan M. Weivoda · Christina L. Inman · Mikolaj Ogrodnik · Mikolaj Ogrodnik · Christine M Hachfeld · Daniel G. Fraser · Jennifer L Onken · Kurt O. Johnson · Grace Verzosa · Larissa G. P. Langhi · Moritz Weigl · Nino Giorgadze · Nathan K. LeBrasseur · Jordan D. Miller · Diana Jurk · Ravinder J. Singh · David B. Allison · David B. Allison · Keisuke Ejima · Keisuke Ejima · Gene B. Hubbard · Yuji Ikeno · Hajrunisa Cubro · Vesna D. Garovic · Xiaonan Hou · S. John Weroha · Paul D. Robbins · Laura J. Niedernhofer · Sundeep Khosla · Tamara Tchkonia · James L. Kirkland · James L. Kirkland
Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA Lesley Hoyles · José-Manuel Fernández-Real · Massimo Federici · Matteo Serino · Matteo Serino · James Abbott · Julie Charpentier · Julie Charpentier · Christophe Heymes · Christophe Heymes · Luque Jl · Anthony E · Richard H. Barton · Julien Chilloux · Antonis Myridakis · Laura Martinez-Gili · José María Moreno-Navarrete · Fadila Benhamed · Azalbert · Azalbert · Blasco-Baque · Blasco-Baque · Josep Puig · Wifredo Ricart · Christopher Tomlinson · Mark Woodbridge · Marina Cardellini · Francesca Davato · Iris Cardolini · Ottavia Porzio · Ottavia Porzio · Paolo Gentileschi · Frédéric Lopez · Frédéric Lopez · Fabienne Foufelle · Sarah Butcher · Elaine Holmes · Jeremy K. Nicholson · C. Postic · Rémy Burcelin · Rémy Burcelin · Marc-Emmanuel Dumas · Marc-Emmanuel Dumas
Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women Rebecca M. Marton · Sergiu P. Paşca · Sergiu P. Paşca
Fetal gene therapy for neurodegenerative disease of infants Nikos Kourtis · Charalampos Lazaris · Kathryn Hockemeyer · Juan Carlos Balandrán · Juan Carlos Balandrán · Juan Carlos Balandrán · Alejandra R. Jimenez · Jasper Mullenders · Jasper Mullenders · Yixiao Gong · Thomas Trimarchi · Kamala Bhatt · Hai Hu · Liza Shrestha · Alberto Ambesi-Impiombato · Michelle A. Kelliher · Elisabeth Paietta · Gabriela Chiosis · Monica L. Guzman · Adolfo A. Ferrando · Aristotelis Tsirigos · Iannis Aifantis · Iannis Aifantis
A human cellular model of amyotrophic lateral sclerosis Russell A. Miller · Russell A. Miller · Yuji Shi · Wenyun Lu · David A. Pirman · Aditi Jatkar · Matthew Blatnik · Hong Wu · César Cárdenas · Min Wan · J. Kevin Foskett · Junyoung O. Park · Yiyi Zhang · William L. Holland · Joshua D. Rabinowitz · Morris J. Birnbaum · Morris J. Birnbaum · Morris J. Birnbaum
Targeting hepatic glutaminase activity to ameliorate hyperglycemia Antoine Marçais · Thierry Walzer · Thierry Walzer
An immunosuppressive pathway for tumor progression Shraddha Chakradhar · Shraddha Chakradhar
Going live: How microRNAs might bring living vaccines back into the fold Zinaida Good · Jolanda Sarno · Astraea Jager · Nikolay Samusik · Nima Aghaeepour · Erin F. Simonds · Leah White · Norman J. Lacayo · Wendy J. Fantl · Grazia Fazio · Giuseppe Gaipa · Andrea Biondi · Robert Tibshirani · Sean C. Bendall · Garry P. Nolan · Kara L. Davis · Kara L. Davis
Cellular origin of human cardiac macrophage populations Giulia Massaro · Citra Nurfarah Zaini Mattar · Andrew Wong · Ernestas Sirka · Suzanne M. K. Buckley · Bronwen R. Herbert · Stefan Karlsson · Dany Perocheau · Derek Burke · Simon Heales · Angela Richard-Londt · Sebastian Brandner · Mylene Huebecker · David A. Priestman · Frances M. Platt · Kevin Mills · Arijit Biswas · Jonathan D. Cooper · Jonathan D. Cooper · Jonathan D. Cooper · Jerry Chan · Jerry Chan · Seng H. Cheng · Simon N. Waddington · Ahad A. Rahim · Ahad A. Rahim
Single-cell developmental classification of B cell precursor acute lymphoblastic leukemia at diagnosis reveals predictors of relapse Qian Xiao · Jibo Wu · Wei-Jia Wang · Shiyang Chen · Yingxia Zheng · Xiaoqing Yu · Katrina Meeth · Mahnaz Sahraei · Alfred L. M. Bothwell · Lieping Chen · Marcus Bosenberg · Jianfeng Chen · Veronika Sexl · Le Sun · Lin Li · Wenwen Tang · Dianqing Wu · Dianqing Wu
DKK2 imparts tumor immunity evasion through β-catenin-independent suppression of cytotoxic immune-cell activation N.K Kisalu · A.H Idris · C Weidle · Y Flores-Garcia · Barbara J. Flynn · Brandon K. Sack · S Murphy · Arne Schön · Ernesto Freire · J.R Fancica · A.B Miller · J Gregory · Sandra March · Hua-Xin Liao · Hua-Xin Liao · Barton F. Haynes · Kevin Wiehe · Ashley M. Trama · Kevin O. Saunders · Morgan A. Gladden · A Monroe · Mattia Bonsignori · Masaru Kanekiyo · Adam K. Wheatley · Adam K. Wheatley · Adrian B. McDermott · S.K Farney · Gwo-Yu Chuang · Bin Zhang · N Kc · S Chakravarty · Peter D. Kwong · Photini Sinnis · Sangeeta N. Bhatia · Stefan H. I. Kappe · B.K.L Sim · Stephen L. Hoffman · Fidel Zavala · M Pancera · Robert A. Seder · Robert A. Seder
De novo NAD + biosynthetic impairment in acute kidney injury in humans Hannah Stower · Hannah Stower
Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo Tony K.T. Lam · David Z.I. Cherney · David Z.I. Cherney
Immunotherapy for glioblastoma: going viral Claire Vinel · Laura Lukjanenko · Aurélie Batut · Simon Deleruyelle · Jean-Philippe Pradère · Sophie Le Gonidec · Alizée Dortignac · Nancy Geoffre · Ophélie Pereira · Sonia Karaz · Umji Lee · Mylène Camus · Karima Chaoui · Etienne Mouisel · Anne Bigot · Vincent Mouly · Mathieu Vigneau · Allan F. Pagano · Angèle Chopard · Fabien Pillard · Sophie Guyonnet · Matteo Cesari · Odile Burlet-Schiltz · Marco Pahor · Jerome N. Feige · Bruno Vellas · Philippe Valet · Cédric Dray · Cédric Dray
Microenvironmental control of breast cancer subtype elicited through paracrine platelet-derived growth factor-CC signaling Pankaj Baral · Benjamin D. Umans · Lu Li · Antonia Wallrapp · Meghna Bist · Talia Kirschbaum · Yibing Wei · Yan Zhou · Vijay K. Kuchroo · Patrick R. Burkett · Bryan G. Yipp · Stephen D. Liberles · Isaac M. Chiu · Isaac M. Chiu
Experimental microbial dysbiosis does not promote disease progression in SIV-infected macaques Anila K. Madiraju · Yang Qiu · Yang Qiu · Rachel J. Perry · Yasmeen Rahimi · Xian-Man Zhang · Dongyan Zhang · João-Paulo G. Camporez · Gary W. Cline · Gina M. Butrico · Bruce E. Kemp · Gregori Casals · Gregory R. Steinberg · Daniel F. Vatner · Kitt Falk Petersen · Gerald I. Shulman · Gerald I. Shulman
Tumor innate immunity primed by specific interferon-stimulated endogenous retroviruses Alexandra M. Ortiz · Jacob K. Flynn · Sarah R. DiNapoli · Ivan Vujkovic-Cvijin · Carly E. Starke · Stephen Lai · MacKenzie E. Long · Ornella Sortino · Carol L. Vinton · Joseph C. Mudd · Leslie Johnston · Kathleen Busman-Sahay · Kathleen Busman-Sahay · Yasmine Belkaid · Jacob D. Estes · Jacob D. Estes · Jacob D. Estes · Jason M. Brenchley · Jason M. Brenchley
Cytotoxic CD8 + T cells recognize and kill Plasmodium vivax –infected reticulocytes Israel Cañadas · Rohit Thummalapalli · Jong Wook Kim · Jong Wook Kim · Shunsuke Kitajima · Russell W. Jenkins · Camilla L. Christensen · Marco Campisi · Yanan Kuang · Yanxi Zhang · Evisa Gjini · Gao Zhang · Tian Tian · D. R. Sen · Diana Miao · Diana Miao · Yu Imamura · Yu Imamura · Tran C. Thai · Brandon Piel · Hideki Terai · Amir R. Aref · Timothy Hagan · Shohei Koyama · Masayuki Watanabe · Hideo Baba · Anika E. Adeni · Christine A. Lydon · Pablo Tamayo · Zhi Wei · Meenhard Herlyn · Thanh U. Barbie · Thanh U. Barbie · Ravindra Uppaluri · Ravindra Uppaluri · Lynnette Marie Sholl · Ewa Sicinska · Jacob Sands · Scott J. Rodig · Kwok-Kin Wong · Kwok-Kin Wong · Cloud P. Paweletz · Hideo Watanabe · David A. Barbie · David A. Barbie
Enhancer mapping uncovers phenotypic heterogeneity and evolution in patients with luminal breast cancer Caroline Junqueira · Caroline Junqueira · Caroline Junqueira · Camila R. R. Barbosa · Pedro Augusto Carvalho Costa · Andréa Teixeira-Carvalho · Guilherme Castro · Sumit Sen Santara · Sumit Sen Santara · Rafael Polidoro Alves Barbosa · Rafael Polidoro Alves Barbosa · Farokh Dotiwala · Farokh Dotiwala · Dhelio Batista Pereira · Lis Ribeiro do Valle Antonelli · Judy Lieberman · Judy Lieberman · Ricardo T. Gazzinelli · Ricardo T. Gazzinelli · Ricardo T. Gazzinelli · Ricardo T. Gazzinelli
Suppression of antitumor T cell immunity by the oncometabolite ( R )-2-hydroxyglutarate Darren K. Patten · Giacomo Corleone · Balázs Győrffy · Balázs Győrffy · Ylenia Perone · Neil Slaven · Iros Barozzi · Edina Erdős · Alina Saiakhova · Kate Goddard · Andrea Vingiani · Sami Shousha · Lőrinc Sándor Pongor · Dimitri Hadjiminas · Gaia Schiavon · Peter Barry · Carlo Palmieri · Rc Coombes · Peter C. Scacheri · Giancarlo Pruneri · Luca Magnani · Luca Magnani
Nociceptor sensory neurons suppress neutrophil and γδ T cell responses in bacterial lung infections and lethal pneumonia Cynthia L. Sears · Drew M. Pardoll · Drew M. Pardoll
The intestinal microbiome influences checkpoint blockade Kimberly M. Christian · Hongjun Song · Guo Li Ming · Guo Li Ming
Biochemical autoregulatory gene therapy for focal epilepsy Lukas Bunse · Stefan Pusch · Theresa Bunse · Felix Sahm · Khwab Sanghvi · Khwab Sanghvi · Mirco Friedrich · Dalia Alansary · Jana K. Sonner · Edward Green · Katrin Deumelandt · Katrin Deumelandt · Michael Kilian · Michael Kilian · Cyril Neftel · Stefanie Uhlig · Tobias Kessler · Anna von Landenberg · Anna Sophie Berghoff · Kelly Marsh · Mya Steadman · Dongwei Zhu · Brandon Nicolay · Benedikt Wiestler · Michael O. Breckwoldt · Michael O. Breckwoldt · Ruslan Al-Ali · Simone Karcher-Bausch · Matthias Bozza · Iris Oezen · Magdalena Kramer · Jochen Meyer · Antje Habel · Jessica Eisel · Gernot Poschet · Michael Weller · Matthias Preusser · Minou Nadji-Ohl · Niklas Thon · Michael Christian Burger · Patrick N. Harter · Miriam Ratliff · Richard Harbottle · Axel Benner · Daniel Schrimpf · Jürgen G. Okun · Christel Herold-Mende · Sevin Turcan · Stefan Kaulfuss · Holger Hess-Stumpp · Karen Bieback · Daniel P. Cahill · Karl H. Plate · Daniel Hänggi · Marion Dorsch · Mario L. Suvà · Barbara A. Niemeyer · Andreas von Deimling · Wolfgang Wick · Michael Platten · Michael Platten
Reducing protein oxidation reverses lung fibrosis Andreas Lieb · Yichen Qiu · Christine L. Dixon · Janosch P. Heller · Matthew C. Walker · Stephanie Schorge · Dimitri M. Kullmann · Dimitri M. Kullmann
Anatomical and functional dichotomy of ocular itch and pain Vikas Anathy · Karolyn G. Lahue · David G. Chapman · Shi B. Chia · Dylan T. Casey · Reem Aboushousha · Jos van der Velden · Evan Elko · Sidra M. Hoffman · David H. McMillan · Jane T. Jones · James D. Nolin · Sarah Abdalla · Robert W. Schneider · David J. Seward · Elle C. Roberson · Matthew D. Liptak · Morgan E. Cousins · Kelly J. Butnor · Douglas J. Taatjes · Ralph C. Budd · Charles G. Irvin · Ye-Shih Ho · Razq Hakem · Kevin K. Brown · Reiko Matsui · Markus Bachschmid · Jose L. Gomez · Naftali Kaminski · Albert van der Vliet · Yvonne M. W. Janssen-Heininger · Yvonne M. W. Janssen-Heininger
Phenotype molding of stromal cells in the lung tumor microenvironment Cheng-Chiu Huang · Cheng-Chiu Huang · Weishan Yang · Changxiong Guo · Haowu Jiang · Fengxian Li · Fengxian Li · Maolei Xiao · Steve Davidson · Guang Yu · Bo Duan · Bo Duan · Tianwen Huang · Andrew J.W. Huang · Qin Liu · Qin Liu
Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound J. Bryan Iorgulescu · J. Bryan Iorgulescu · David A. Reardon · David A. Reardon · E. Antonio Chiocca · E. Antonio Chiocca · Catherine J. Wu · Catherine J. Wu · Catherine J. Wu
Oncogenic hijacking of the stress response machinery in T cell acute lymphoblastic leukemia Afam A. Okoye · Scott G. Hansen · Mukta Vaidya · Yoshinori Fukazawa · Haesun Park · Derick M. Duell · Richard Lum · Colette M. Hughes · Abigail B. Ventura · Emily Ainslie · Julia C. Ford · David W. Morrow · Roxanne M. Gilbride · Alfred W. Legasse · Joseph Hesselgesser · Romas Geleziunas · Yuan Li · Kelli Oswald · Rebecca Shoemaker · Randy Fast · William J. Bosche · Bhavesh R. Borate · Paul T. Edlefsen · Michael K. Axthelm · Louis J. Picker · Jeffrey D. Lifson · Jeffrey D. Lifson
The exerkine apelin reverses age-associated sarcopenia Seung Tae Kim · Razvan Cristescu · Adam J. Bass · Kyoung-Mee Kim · Justin I. Odegaard · Kyung Chan Kim · Xiao Qiao Liu · Xinwei Sher · Hun Jung · Mijin Lee · Sujin Lee · Se Hoon Park · Joon Oh Park · Young Suk Park · Ho Yeong Lim · Hyuk Lee · Min-Gew Choi · AmirAli Talasaz · Peter Soonmo Kang · Jonathan D. Cheng · Andrey Loboda · Jeeyun Lee · Won Ki Kang · Won Ki Kang
Clinically applicable deep learning for diagnosis and referral in retinal disease Peng Jiang · Shengqing Gu · Deng Pan · Jingxin Fu · Avinash Sahu · Xihao Hu · Ziyi Li · Nicole Traugh · Xia Bu · Bo Li · Bo Li · Jun Liu · Gordon J. Freeman · Myles Brown · Kai W. Wucherpfennig · X. Shirley Liu · X. Shirley Liu
An antiviral for smallpox Sapna Devi · Anqi Li · Clare L V Westhorpe · Camden Lo · Latasha D. Abeynaike · Sarah L. Snelgrove · Pam Hall · Joshua D. Ooi · Christopher G. Sobey · A. Richard Kitching · Michael J. Hickey · Michael J. Hickey
Regional variation limits applications of healthy gut microbiome reference ranges and disease models Hannah Stower · Hannah Stower
Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors Yan He · Wei Wu · Wei Wu · Hui-Min Zheng · Pan Li · Daniel McDonald · Hua-Fang Sheng · Mu-Xuan Chen · Zi-Hui Chen · Gui-Yuan Ji · Zhong-Dai-Xi Zheng · Prabhakar Mujagond · Xiao-Jiao Chen · Zu-Hua Rong · Peng Chen · Li-Yi Lyu · Xian Wang · Chong-Bin Wu · Nan Yu · Yanjun Xu · Jia Yin · Jeroen Raes · Jeroen Raes · Rob Knight · Wenjun Ma · Hong-Wei Zhou · Hong-Wei Zhou
Publisher Correction: Global characterization of T cells in non-small-cell lung cancer by single-cell sequencing Pakawat Chongsathidkiet · Christina Jackson · Shohei Koyama · Franziska Loebel · Xiuyu Cui · S. Harrison Farber · S. Harrison Farber · Karolina Woroniecka · Aladine A. Elsamadicy · Cosette Dechant · Hanna Kemeny · Luis Sanchez-Perez · Tooba A. Cheema · Nicholas Souders · James E. Herndon · Jean-Valery Coumans · Jeffrey I. Everitt · Brian V. Nahed · John H. Sampson · Michael D. Gunn · Robert L. Martuza · Glenn Dranoff · William T. Curry · Peter E. Fecci · Peter E. Fecci
Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma Xinyi Guo · Yuanyuan Zhang · Liangtao Zheng · Chunhong Zheng · Jintao Song · Qiming Zhang · Boxi Kang · Zhouzerui Liu · Liang Jin · Rui Xing · Ranran Gao · Minghui Dong · Xueda Hu · Xianwen Ren · Dennis Kirchhoff · Helge Gottfried Roider · Yan T · Zemin Zhang · Zemin Zhang
Author Correction: Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer Noam Auslander · Noam Auslander · Gao Zhang · Joo Sang Lee · Joo Sang Lee · Dennie T. Frederick · Benchun Miao · Tabea Moll · Tian Tian · Zhi Wei · Sanna Madan · Sanna Madan · Ryan J. Sullivan · Genevieve M. Boland · Keith T. Flaherty · Meenhard Herlyn · Eytan Ruppin · Eytan Ruppin · Eytan Ruppin
Blood-based tumor mutational burden as a predictor of clinical benefit in non-small-cell lung cancer patients treated with atezolizumab Yonathan Lissanu Deribe · Yuting Sun · Christopher Terranova · Fatima Khan · Juan Martinez-Ledesma · Guang Gao · Robert A. Mullinax · Tin Khor · Ningping Feng · Yu-Hsi Lin · Chia-Chin Wu · Claudia Reyes · Qian Peng · Frederick Robinson · Akira Inoue · Veena Kochat · Chang-Gong Liu · John M. Asara · Cesar A. Moran · Florian Muller · Jing Wang · Bingliang Fang · Vali Papadimitrakopoulou · Ignacio I. Wistuba · Kunal Rai · Joseph R. Marszalek · P. Andrew Futreal · P. Andrew Futreal
A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells Yang Li · Marije Oosting · Patrick Deelen · Isis Ricaño-Ponce · Sanne P. Smeekens · Martin Jaeger · Vasiliki Matzaraki · Morris A. Swertz · Ramnik J. Xavier · Lude Franke · Cisca Wijmenga · Leo A. B. Joosten · Vinod Kumar · Mihai G. Netea · Mihai G. Netea
Comprehensive molecular characterization of clinical responses to PD-1 inhibition in metastatic gastric cancer Adam B. Roberts · Xiaodong Gu · Jennifer A. Buffa · Alex G. Hurd · Alex G. Hurd · Zeneng Wang · Weifei Zhu · Nilaksh Gupta · Sarah M. Skye · David B. Cody · Bruce S. Levison · William T. Barrington · Matthew W. Russell · Jodie Michelle Reed · Ashraf Duzan · Ashraf Duzan · Jennifer Lang · Xiaoming Fu · Lin Li · Alex J. Myers · Alex J. Myers · Suguna Rachakonda · Joseph A. DiDonato · J. Mark Brown · Valentin Gogonea · Valentin Gogonea · Aldons J. Lusis · Jose Carlos Garcia-Garcia · Stanley L. Hazen · Stanley L. Hazen
Depicting the composition of gut microbiota in a population with varied ethnic origins but shared geography Sunad Rangarajan · Nathaniel B. Bone · Anna A. Zmijewska · Shaoning Jiang · Dae Won Park · Dae Won Park · Karen Bernard · Morgan L. Locy · Saranya Ravi · Jessy Deshane · Roslyn B. Mannon · Edward Abraham · Victor M. Darley-Usmar · Victor J. Thannickal · Jaroslaw W. Zmijewski · Jaroslaw W. Zmijewski
Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response Mélanie Deschasaux · Kristien E. Bouter · Andrei Prodan · Evgeni Levin · Albert K. Groen · Hilde Herrema · Valentina Tremaroli · Guido J. Bakker · Ilias Attaye · Sara-Joan Pinto-Sietsma · Daniël H. van Raalte · Marieke B. Snijder · Mary Nicolaou · Ron J. G. Peters · Aeilko H. Zwinderman · Fredrik Bäckhed · Fredrik Bäckhed · Max Nieuwdorp · Max Nieuwdorp · Max Nieuwdorp · Max Nieuwdorp
Author Correction: Metformin reverses established lung fibrosis in a bleomycin model Christopher Anthony Vakulskas · Daniel P. Dever · Garrett Richard Rettig · Rolf Turk · Ashley M. Jacobi · Michael A. Collingwood · Nicole M. Bode · Matthew S. McNeill · Shuqi Yan · Joab Camarena · Ciaran M. Lee · So Hyun Park · Volker Wiebking · Rasmus O. Bak · Natalia Gomez-Ospina · Mara Pavel-Dinu · Wenchao Sun · Gang Bao · Matthew H. Porteus · Mark A. Behlke · Mark A. Behlke
Learning from bacterial competition in the host to develop antimicrobials Jeffrey De Fauw · Joseph R. Ledsam · Bernardino Romera-Paredes · Stanislav Nikolov · Nenad Tomasev · Sam Blackwell · Harry Askham · Xavier Glorot · Brendan O’Donoghue · Daniel Visentin · George van den Driessche · Balaji Lakshminarayanan · Clemens Meyer · Faith Mackinder · Simon Bouton · Kareem Ayoub · Reena Chopra · Dominic King · Alan Karthikesalingam · Cían Hughes · Rosalind Raine · Julian Hughes · Dawn A. Sim · Catherine Egan · Adnan Tufail · Hugh Montgomery · Demis Hassabis · Geraint Rees · Trevor Back · Peng T. Khaw · Mustafa Suleyman · Julien Cornebise · Pearse A. Keane · Olaf Ronneberger · Olaf Ronneberger
Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent Gabrielle S. Wong · Gabrielle S. Wong · Jin Zhou · Jie Bin Liu · Zhong Wu · Xinsen Xu · Tianxia Li · David Xu · Steven E. Schumacher · Jens Puschhof · James McFarland · James McFarland · Charles Zou · Austin M. Dulak · Les Henderson · Peng Xu · Emily O’Day · Rachel Rendak · Wei-Li Liao · Fabiola Cecchi · Todd Hembrough · Sarit Schwartz · Christopher Szeto · Anil K. Rustgi · Kwok-Kin Wong · J. Alan Diehl · Karin Jensen · Francesco Graziano · Annamaria Ruzzo · Shaunt Fereshetian · Philipp Mertins · Philipp Mertins · Steven A. Carr · Rameen Beroukhim · Kenichi Nakamura · Eiji Oki · Masayuki Watanabe · Masayuki Watanabe · Hideo Baba · Yu Imamura · Yu Imamura · Daniel V.T. Catenacci · Adam J. Bass · Adam J. Bass
Development of a gut microbe–targeted nonlethal therapeutic to inhibit thrombosis potential Delphine Gomez · Richard A. Baylis · Brittany G. Durgin · Alexandra A C Newman · Gabriel F. Alencar · Sidney Mahan · Cynthia St. Hilaire · Werner Müller · Ari Waisman · Sheila E. Francis · Emmanuel Pinteaux · Gwendalyn J. Randolph · Hermann Gram · Gary K. Owens · Gary K. Owens
Interleukin-1β has atheroprotective effects in advanced atherosclerotic lesions of mice Hannah Stower · Hannah Stower
Genetically engineered human cortical spheroid models of tuberous sclerosis Manuela Raffatellu · Manuela Raffatellu
Restorative effects of human neural stem cell grafts on the primate spinal cord Tamer Sallam · Marius Jones · Brandon J. Thomas · Xiaohui Wu · Thomas Gilliland · Kevin Qian · Ascia Eskin · David Casero · Zhengyi Zhang · Jaspreet Sandhu · David Salisbury · Prashant Rajbhandari · Mete Civelek · Cynthia Hong · Ayaka Ito · Xin Liu · Bence Daniel · Aldons J. Lusis · Julian P. Whitelegge · Laszlo Nagy · Antonio Castrillo · Stephen T. Smale · Peter Tontonoz · Peter Tontonoz
A wasted early warning Sapna Devi · Anqi Li · Clare L V Westhorpe · Camden Lo · Latasha D. Abeynaike · Sarah L. Snelgrove · Pam Hall · Joshua D. Ooi · Christopher G. Sobey · A. Richard Kitching · Michael J. Hickey · Michael J. Hickey
Author Correction: Targeting wild-type KRAS -amplified gastroesophageal cancer through combined MEK and SHP2 inhibition J. Titano · Marcus A. Badgeley · Javin Schefflein · Margaret Pain · Andres Su · Michael Cai · Nathaniel C. Swinburne · John Zech · Jun Kim · Joshua B. Bederson · J Mocco · Burton P. Drayer · Joseph Lehar · Samuel K. Cho · Anthony B. Costa · Eric K. Oermann · Eric K. Oermann
Automated deep-neural-network surveillance of cranial images for acute neurologic events John D. Blair · Dirk Hockemeyer · Helen S. Bateup · Helen S. Bateup · Helen S. Bateup
Gut checkpoint: A rising cancer treatment may get a boost from intestinal bacteria Ephron S. Rosenzweig · John H. Brock · Paul Lu · Hiromi Kumamaru · Ernesto A. Salegio · Ken Kadoya · Janet L Weber · Justine J Liang · Rod Moseanko · Stephanie Hawbecker · J. Russell Huie · Leif A. Havton · Yvette S. Nout-Lomas · Adam R. Ferguson · Michael S. Beattie · Jacqueline C. Bresnahan · Mark H. Tuszynski · Mark H. Tuszynski
Senolytics improve physical function and increase lifespan in old age Diether Lambrechts · Els Wauters · Bram Boeckx · Sara Aibar · David Nittner · Oliver Burton · Ayse Bassez · Herbert Decaluwé · Andreas Pircher · Kathleen Van den Eynde · Birgit Weynand · Erik Verbeken · Paul De Leyn · Adrian Liston · Johan Vansteenkiste · Peter Carmeliet · Stein Aerts · Bernard Thienpont · Bernard Thienpont
Molecular definition of a metastatic lung cancer state reveals a targetable CD109-Janus kinase-Stat axis Ajit Vikram · Christopher M Lewarchik · Jin-Young Yoon · Asma Naqvi · Santosh Kumar · Gina Morgan · Julia S. Jacobs · Qiuxia Li · Young-Rae Kim · Modar Kassan · Jing Liu · Mohanad Gabani · Ajay Kumar · Haider Mehdi · Xiaodong Zhu · Xiaoqun Guan · William Kutschke · Xiaoming Zhang · Ryan L. Boudreau · Shengchuan Dai · Daniel S. Matasic · Saet-Byel Jung · Kenneth B. Margulies · Vikas Kumar · Markus Bachschmid · Barry London · Kaikobad Irani · Kaikobad Irani
The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia Chen-Hua Chuang · Peyton Greenside · Zoë N. Rogers · Jennifer J. Brady · Dian Yang · Rosanna K. Ma · Deborah R. Caswell · Shin-Heng Chiou · Aidan F Winters · Barbara M. Grüner · Gokul Ramaswami · Andrew L Spencley · Kimberly E Kopecky · Leanne C. Sayles · E. Alejandro Sweet-Cordero · Jin Billy Li · Anshul Kundaje · Monte M. Winslow · Monte M. Winslow
Sirtuin 1 regulates cardiac electrical activity by deacetylating the cardiac sodium channel Pazit Beckerman · Jing Bi-Karchin · Ae Seo Deok Park · Chengxiang Qiu · Patrick D. Dummer · Irfana Soomro · Carine M. Boustany-Kari · Steven S. Pullen · Jeffrey H. Miner · Chien-An Andy Hu · Tibor Rohacs · Kazunori Inoue · Shuta Ishibe · Moin A. Saleem · Matthew Palmer · Ana Maria Cuervo · Jeffrey B. Kopp · Katalin Susztak · Katalin Susztak
Targeting c-FOS and DUSP1 abrogates intrinsic resistance to tyrosine-kinase inhibitor therapy in BCR-ABL-induced leukemia Jianjun Gao · John F. Ward · Curtis A. Pettaway · Lewis Zhichang Shi · Sumit K. Subudhi · Luis Vence · Hao Zhao · Jianfeng Chen · Hong Chen · Patricia Troncoso · James P. Allison · Christopher J. Logothetis · Ignacio I. Wistuba · Manuel A. Sepulveda · Jingjing Sun · Jennifer A. Wargo · Jorge Blando · Padmanee Sharma · Padmanee Sharma
An epitranscriptomic vulnerability in myeloid malignancies Carrie Arnold · Carrie Arnold
Mapping the mind: A new tool reveals uncharted territories in the brain Nina Fenouille · Christopher F. Bassil · Issam Ben-Sahra · Lina Benajiba · Gabriela Alexe · Gabriela Alexe · Gabriela Alexe · Azucena Ramos · Yana Pikman · Amy Saur Conway · Michael R. Burgess · Qing Li · Frederic Luciano · Patrick Auberger · Ilene Galinsky · Daniel J. DeAngelo · Richard Stone · Yi Zhang · Archibald S. Perkins · Kevin Shannon · Michael T. Hemann · Alexandre Puissant · Alexandre Puissant · Kimberly Stegmaier · Kimberly Stegmaier · Kimberly Stegmaier
Corrigendum: Zika viral dynamics and shedding in rhesus and cynomolgus macaques Madeleine Johnson · Madeleine Johnson
Stalking new vaccines: Methods that target the stems of viral proteins could put universal vaccines within reach Madeleine J. Bunders · Marcus Altfeld · Marcus Altfeld
HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures Matthew D. Lynes · Luiz O Leiria · Morten Lundh · Alexander Bartelt · Farnaz Shamsi · Tian Lian Huang · Hirokazu Takahashi · Michael F. Hirshman · Christian Schlein · Alexandra Lee · Lisa A. Baer · Francis J. May · Fei Gao · Niven R. Narain · Emily Y. Chen · Michael A. Kiebish · Aaron M. Cypess · Matthias Blüher · Laurie J. Goodyear · Gökhan S. Hotamisligil · Kristin I. Stanford · Yu-Hua Tseng · Yu-Hua Tseng
Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice Pi-Xiao Wang · Yan-Xiao Ji · Xiao-Jing Zhang · Ling-Ping Zhao · Zhen-Zhen Yan · Peng Zhang · Li-Jun Shen · Xia Yang · Jing Fang · Song Tian · Xueyong Zhu · Jun Gong · Xin Zhang · Qiao-Fang Wei · Yong Wang · Jing Li · Lu Wan · Qingguo Xie · Zhi-Gang She · Zhihua Wang · Zan Huang · Hongliang Li · Hongliang Li
Can NK cells purge HIV sanctuaries Yuval Nir · Thomas Andrillon · Amit Marmelshtein · Nanthia Suthana · Chiara Cirelli · Giulio Tononi · Itzhak Fried · Itzhak Fried
Gpr124 is essential for blood–brain barrier integrity in central nervous system disease Helen Davies · Dominik Glodzik · Sandro Morganella · Lucy R. Yates · Lucy R. Yates · Johan Staaf · Xueqing Zou · Manasa Ramakrishna · Manasa Ramakrishna · Sancha Martin · Sandrine Boyault · Anieta M. Sieuwerts · Peter T. Simpson · Tari A Ta King · Keiran Raine · Jórunn Erla Eyfjörd · Gu G. Kong · Åke Borg · Ewan Birney · Hendrik G. Stunnenberg · Marc J. van de Vijver · Anne Lise Børresen-Dale · John W.M. Martens · Paul N. Span · Sunil R. Lakhani · Sunil R. Lakhani · Anne Vincent-Salomon · Christos Sotiriou · Andrew Tutt · Alastair M. Thompson · Steven Van Laere · Andrea L. Richardson · Alain Viari · Peter J. Campbell · Michael R. Stratton · Serena Nik-Zainal · Serena Nik-Zainal · Serena Nik-Zainal
Natural killer cells migrate into and control simian immunodeficiency virus replication in lymph node follicles in African green monkeys Alexandra C Schmiechen · Pedro J Batista · Pedro J Batista
[alpha]5 nicotinic receptors link smoking to schizophrenia Junlei Chang · Michael R. Mancuso · Carolina M. Maier · Xibin Liang · Kanako Yuki · Lu Yang · Jeffrey W Kwong · Jing Wang · Varsha Rao · Mario Vallon · Cynthia Kosinski · J J Haijing Zhang · Amanda T. Mah · Lijun Xu · L Li · Sharareh Gholamin · Teresa F. Reyes · Rui Li · Frank Kuhnert · Xiaoyuan Han · Jenny Yuan · Shin-Heng Chiou · Ari D. Brettman · Lauren Daly · David C Corney · Samuel H. Cheshier · Linda D. Shortliffe · Xiwei Wu · Michael Snyder · Pak H. Chan · Rona G. Giffard · Howard Y. Chang · Katrin Andreasson · Calvin J. Kuo · Calvin J. Kuo
The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue Sebastian Bender · Sebastian Bender · Jan Gronych · Hans-Jörg Warnatz · Barbara Hutter · Susanne Gröbner · Marina Ryzhova · Elke Pfaff · Elke Pfaff · Volker Hovestadt · Florian Weinberg · Sebastian Halbach · Marcel Kool · Paul A. Northcott · Dominik Sturm · Dominik Sturm · Lynn Bjerke · Thomas Zichner · Adrian M. Stütz · Kathrin Schramm · Bingding Huang · Ivo Buchhalter · Michael Heinold · Thomas Risch · Barbara C. Worst · Barbara C. Worst · Cornelis M. van Tilburg · Cornelis M. van Tilburg · Ursula Weber · Marc Zapatka · Benjamin Raeder · David Milford · Sabine Heiland · Christof von Kalle · Christopher Previti · Chris Lawerenz · Andreas E. Kulozik · Andreas Unterberg · Olaf Witt · Andreas von Deimling · David Capper · David Capper · Nathalene Truffaux · Nathalene Truffaux · Jacques Grill · Jacques Grill · Nada Jabado · Astrid M Sehested · David Sumerauer · Dorra H’mida-Ben Brahim · Saoussen Trabelsi · Ho Keung Ng · David Zagzag · Jeffrey C. Allen · Matthias A. Karajannis · Nicholas G. Gottardo · Chris Jones · Jan O. Korbel · Sabine Schmidt · Stephan Wolf · Guido Reifenberger · Jörg Felsberg · Benedikt Brors · Christel Herold-Mende · Hans Lehrach · Tilman Brummer · Andrey Korshunov · Roland Eils · Marie-Laure Yaspo · Stefan M. Pfister · Peter Lichter · David T. W. Jones · David T. W. Jones
Selective neuronal lapses precede human cognitive lapses following sleep deprivation Matthew D. Lynes · Luiz O Leiria · Morten Lundh · Alexander Bartelt · Farnaz Shamsi · Tian Lian Huang · Hirokazu Takahashi · Michael F. Hirshman · Christian Schlein · Alexandra Lee · Lisa A. Baer · Francis J. May · Fei Gao · Niven R. Narain · Emily Y. Chen · Michael A. Kiebish · Aaron M. Cypess · Matthias Blüher · Laurie J. Goodyear · Gökhan S. Hotamisligil · Kristin I. Stanford · Yu-Hua Tseng · Yu-Hua Tseng
Autoimmunity against a defective ribosomal insulin gene product in type 1 diabetes Sophia Frentzas · Eve Simoneau · Victoria L. Bridgeman · Peter B. Vermeulen · Shane Foo · Eleftherios Kostaras · Mark R. Nathan · Andrew Wotherspoon · Zu Hua Gao · Yu Shi · Gert Van den Eynden · Frances Daley · Clare Peckitt · Xianming Tan · Ayat Salman · Anthoula Lazaris · Patrycja Gazinska · Tracy J. Berg · Zak Eltahir · Laila Ritsma · Jacco van Rheenen · Alla Khashper · Gina Brown · Hanna Nyström · Malin Sund · Steven Van Laere · Evelyne Loyer · Luc Dirix · David Cunningham · Peter Metrakos · Andrew R. Reynolds · Andrew R. Reynolds
Diagnosis of Zika virus infection on a nanotechnology platform Maria Jl Kracht · Menno van Lummel · Tatjana Nikolic · Antoinette M. Joosten · Sandra Laban · Arno R. van der Slik · Peter A. van Veelen · Françoise Carlotti · Eelco J.P. de Koning · Rob C. Hoeben · Arnaud Zaldumbide · Bart O. Roep · Bart O. Roep
Corrigendum: The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue Shraddha Chakradhar · Shraddha Chakradhar
An emerging role for neutrophil extracellular traps in noninfectious disease Junjian Wang · June X. Zou · Xiaoqian Xue · Demin Cai · Yan Zhang · Zhijian Duan · Qiuping Xiang · Joy C. Yang · Maggie C. Louie · Alexander D. Borowsky · Allen C. Gao · Christopher P. Evans · Kit S. Lam · Jianzhen Xu · Hsing Jien Kung · Ronald M. Evans · Yong Xu · Hong Wu Chen · Hong Wu Chen
Deficiency of the hepatokine selenoprotein P increases responsiveness to exercise in mice through upregulation of reactive oxygen species and AMP-activated protein kinase in muscle Selina K. Jorch · Paul Kubes · Paul Kubes
Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates Peter M. Bruno · Yunpeng Liu · Ga Young Park · Junko Murai · Catherine E Koch · Timothy J Eisen · Justin R. Pritchard · Yves Pommier · Stephen J. Lippard · Michael T. Hemann · Michael T. Hemann
EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas Hirofumi Misu · Hiroaki Takayama · Yoshiro Saito · Yuichiro Mita · Akihiro Kikuchi · Kiyoaki Ishii · Keita Chikamoto · Takehiro Kanamori · Natsumi Tajima · Fei Lan · Yumie Takeshita · Masao Honda · Mutsumi Tanaka · Seiji Kato · Naoto Matsuyama · Yuya Yoshioka · Kaito Iwayama · Nobuhiko Akazawa · Seiji Maeda · Kazuhiro Takekoshi · Seiichi Matsugo · Noriko Noguchi · Shuichi Kaneko · Toshinari Takamura · Toshinari Takamura
Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas Faizaan Mohammad · Simon Weissmann · Benjamin Leblanc · Deo Prakash Pandey · Jonas W. Højfeldt · Itys Comet · Chunqin Zheng · Jens Vilstrup Johansen · Nicolas Rapin · Bo T. Porse · Andrey Tvardovskiy · Ole Nørregaard Jensen · Nagore G. Olaciregui · Cinzia Lavarino · Mariona Suñol · Carmen de Torres · Jaume Mora · Angel M. Carcaboso · Kristian Helin · Kristian Helin
Predictable response: Finding optimal drugs and doses using artificial intelligence Michael P. Czech · Michael P. Czech
Glucocorticoid hormone-induced chromatin remodeling enhances human hematopoietic stem cell homing and engraftment Arturo Vegas · Omid Veiseh · Madsörtler G · Jeffrey R. Millman · Felicia W. Pagliuca · Andrew Bader · Joshua C. Doloff · Jie Li · Michael Chen · Karsten Olejnik · Hok Hei Tam · Siddharth Jhunjhunwala · Erin Langan · Stephanie Aresta-Dasilva · Srujan Gandham · James J. McGarrigle · Matthew A. Bochenek · Jennifer Hollister-Lock · Jose Oberholzer · Dale L. Greiner · Gordon C. Weir · Douglas A. Melton · Robert Langer · Daniel G. Anderson · Daniel G. Anderson
The shape of the microbiome in early life Bin Guo · Xinxin Huang · Scott Cooper · Hal E. Broxmeyer · Hal E. Broxmeyer
Taking inventory of metastasis effectors Erika von von Mutius · Erika von von Mutius
A protein puzzle: Untangling the mysterious condition of amyloidosis Laura Pisarsky · Jinxiang Dai · Cyrus M. Ghajar · Cyrus M. Ghajar
Womb zoom: What advances in fetal and newborn imaging have revealed Shraddha Chakradhar · Shraddha Chakradhar
A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress Wudan Yan · Wudan Yan
VISTA is an inhibitory immune checkpoint that is increased after ipilimumab therapy in patients with prostate cancer Wang Junjian · Zou June X · Cai Demin · Duan Zhijian · Lam Kit S · Kung Hsing‐Jien · Chen Hong‐Wu · Xue Xiaoqian · Zhang Yan · Xiang Qiuping · Xu Yong · Yang Joy C · Gao Allen C · Evans Christopher P · Louie Maggie C · Borowsky Alexander D · Xu Jianzhen · Evans Ronald M · Evans Ronald M
Keap1 loss promotes Kras -driven lung cancer and results in dependence on glutaminolysis David Lagares · Parisa Ghassemi-Kakroodi · Caroline Tremblay · Alba Santos · Clemens K. Probst · Alicia Franklin · Daniela M Santos · Paula Grasberger · Neil Ahluwalia · Sydney B. Montesi · Barry S. Shea · Katharine E. Black · Rachel S. Knipe · Meryem Blati · Murray Baron · Brian Wu · Hassan Fahmi · Rajiv Gandhi · Annie Pardo · Moisés Selman · Jiangping Wu · Jean-Pierre Pelletier · Johanne Martel-Pelletier · Andrew M. Tager · Mohit Kapoor · Mohit Kapoor
Regulatory T cells impede acute and long-term immunity to blood-stage malaria through CTLA-4 Nisha M. Badders · Ane Korff · Helen Cristina Miranda · Pradeep K. Vuppala · Rebecca B. Smith · Brett J. Winborn · Emmanuelle R. J. Quemin · Bryce L. Sopher · Jennifer Dearman · James Messing · Nam Chul Kim · Jennifer C. Moore · Brian D. Freibaum · Anderson P. Kanagaraj · Baochang Fan · Heather Tillman · Ping Chung Chen · Yingzhe Wang · Burgess B. Freeman · Yimei Li · Hong Joo Kim · Albert R. La Spada · Albert R. La Spada · J. Paul Taylor · J. Paul Taylor
The N 6 -methyladenosine (m 6 A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells Simon J. Draper · Matthew K. Higgins · Matthew K. Higgins
Cytoplasmic p53 couples oncogene-driven glucose metabolism to apoptosis and is a therapeutic target in glioblastoma Ronald J. Hause · Colin C. Pritchard · Jay Shendure · Stephen J. Salipante · Stephen J. Salipante
Engineering MeCP2 to spy on its targets Wilson X. Mai · Laura Gosa · Veerle W Daniels · Lisa Ta · Jonathan Tsang · Brian Higgins · W Blake Gilmore · Nicholas A. Bayley · Mitra Dehghan Harati · Jason T. Lee · William H. Yong · Harley I. Kornblum · Steven J. Bensinger · Paul S. Mischel · P. Nagesh Rao · Peter M. Clark · Timothy F. Cloughesy · Anthony Letai · David Nathanson · David Nathanson
Cancer stem cells revisited Patricia M. Horvath · Lisa M. Monteggia · Lisa M. Monteggia
Activation of intestinal hypoxia-inducible factor 2α during obesity contributes to hepatic steatosis Eduard Batlle · Hans Clevers · Hans Clevers
GDF15 and energy balance: homing in on a mechanism Cen Xie · Tomoki Yagai · Yuhong Luo · Xianyi Liang · Xianyi Liang · Tao Chen · Qiong Wang · Dong-Xue Sun · Jie Zhao · Sadeesh K. Ramakrishnan · Lulu Sun · Lulu Sun · Chunmei Jiang · Chunmei Jiang · Xiang Xue · Yuan Tian · Kristopher W. Krausz · Andrew D. Patterson · Yatrik M. Shah · Yue Wu · Changtao Jiang · Changtao Jiang · Frank J. Gonzalez · Frank J. Gonzalez
Noncoding RNAs as effective markers in cancer-care management Irene Cimino · Anthony P. Coll · Giles S. H. Yeo · Giles S. H. Yeo
Defining total-body AIDS-virus burden with implications for curative strategies Ivan Raimondi · Maite Huarte · Maite Huarte
HDAC3 sets the timer on muscle fuel switching Maksim Mamonkin · Helen E. Heslop · Helen E. Heslop
Sympathetic neuron–associated macrophages contribute to obesity by importing and metabolizing norepinephrine Jacob D. Estes · Cissy Kityo · Francis Ssali · Louise Swainson · Krystelle Nganou Makamdop · Gregory Q. Del Prete · Steven G. Deeks · Paul A. Luciw · Jeffrey G. Chipman · Gregory J. Beilman · Torfi Hoskuldsson · Alexander Khoruts · Jodi Anderson · Claire Deleage · Jacob Jasurda · Thomas E. Schmidt · Michael Hafertepe · Samuel P. Callisto · Hope Pearson · Thomas Reimann · Jared Schuster · Jordan Schoephoerster · Peter J. Southern · Katherine E. Perkey · Liang Shang · Stephen W. Wietgrefe · Courtney V. Fletcher · Jeffrey D. Lifson · Joseph M. McCune · Ashley T. Haase · Timothy W. Schacker · Timothy W. Schacker
Angst about exclusivity: The potential cost of incentivizing makers of generic drugs Roksana M. Pirzgalska · Elsa Seixas · Jason S. Seidman · Verena M. Link · Noelia Martínez Sánchez · Inês Mahú · Raquel Mendes · Vitka Gres · Nadiya Kubasova · Imogen Morris · Bernardo A Arús · Chelsea M Larabee · Miguel Vasques · Francisco Tortosa · Ana Laura Sousa · Sathyavathy Anandan · Erin M. Tranfield · Maureen K Hahn · Matteo Iannacone · Nathanael J. Spann · Christopher K. Glass · Ana I. Domingos · Ana I. Domingos
Targeting glioma stem cells through combined BMI1 and EZH2 inhibition Shraddha Chakradhar · Roxanne Khamsi · Roxanne Khamsi
Omega-3 fatty acid epoxides are autocrine mediators that control the magnitude of IgE-mediated mast cell activation Xun Jin · Xun Jin · Xun Jin · Leo Kim · Leo Kim · Leo Kim · Qiulian Wu · Qiulian Wu · Lisa C Wallace · Briana Prager · Briana Prager · Briana Prager · Tanwarat Sanvoranart · Ryan C. Gimple · Ryan C. Gimple · Ryan C. Gimple · Xiuxing Wang · Xiuxing Wang · Stephen C. Mack · Stephen C. Mack · Tyler E. Miller · Tyler E. Miller · Ping Huang · Claudia L.L. Valentim · Qi Gang Zhou · Jill S. Barnholtz-Sloan · Shideng Bao · Andrew E. Sloan · Jeremy N. Rich · Jeremy N. Rich
Sex-specific disease-associated modules for depression Yuta Shimanaka · Nozomu Kono · Nozomu Kono · Yoshitaka Taketomi · Makoto Arita · Yoshimichi Okayama · Yuki Tanaka · Yasumasa Nishito · Tatsuki Mochizuki · Hiroyuki Kusuhara · Alexander Adibekian · Benjamin F. Cravatt · Makoto Murakami · Hiroyuki Arai · Hiroyuki Arai
The enteric virome in hematopoietic stem cell transplantation: ready for its close-up Ronald S. Duman · Ronald S. Duman
Human-monoclonal-antibody therapy protects nonhuman primates against advanced Lassa fever Shuichiro Takashima · Alan M. Hanash · Alan M. Hanash
Clonal evolution in leukemia Nicolas Coudray · Paolo Santiago Ocampo · Theodore Sakellaropoulos · Navneet Narula · Matija Snuderl · David Fenyö · Andre L. Moreira · Narges Razavian · Aristotelis Tsirigos · Aristotelis Tsirigos
Chromosome 1q21.3 amplification is a trackable biomarker and actionable target for breast cancer recurrence Adolfo A. Ferrando · Carlos López-Otín · Carlos López-Otín
Targeting cellular senescence prevents age-related bone loss in mice Jian Yuan Goh · Min Feng · Wenyu Wang · Gokce Oguz · Gokce Oguz · Siti Maryam J. M. Yatim · Puay Leng Lee · Yi Bao · Tse Hui Lim · Panpan Wang · Wai Leong Tam · Wai Leong Tam · Annette R. Kodahl · Maria Bibi Lyng · Suman Sarma · Selena Y. Lin · Alexander Lezhava · Yoon Sim Yap · Alvin S. T. Lim · Dave S.B. Hoon · Henrik J. Ditzel · Soo-Chin Lee · Soo-Chin Lee · Ern Yu Tan · Ern Yu Tan · Qiang Yu · Qiang Yu
Targeting mitochondrial oxidative phosphorylation eradicates therapy-resistant chronic myeloid leukemia stem cells Wenfei Sun · Hua Dong · Anton S. Becker · Dianne H. Dapito · Salvatore Modica · Gerald Grandl · Lennart Opitz · Lennart Opitz · Vissarion Efthymiou · Leon G. Straub · Gitalee Sarker · Miroslav Balaz · Lucia Balazova · Aliki Perdikari · Elke Kiehlmann · Sara Bacanovic · Caroline Zellweger · Daria Peleg-Raibstein · Pawel Pelczar · Wolf Reik · Wolf Reik · Irene A. Burger · Ferdinand von Meyenn · Ferdinand von Meyenn · Christian Wolfrum · Christian Wolfrum
Biotin tagging of MeCP2 in mice reveals contextual insights into the Rett syndrome transcriptome Elodie M. Kuntz · Pablo Baquero · Alison M. Michie · Karen Dunn · Saverio Tardito · Tessa L. Holyoake · G. Vignir Helgason · Eyal Gottlieb · Eyal Gottlieb
KLF4-dependent perivascular cell plasticity mediates pre-metastatic niche formation and metastasis Brian S. Johnson · Ying-Tao Zhao · Maria Fasolino · Janine M. Lamonica · Yoon Jung Kim · George Georgakilas · Kathleen H Wood · Daniel Bu · Yue Cui · Darren Goffin · Golnaz Vahedi · Tae Hoon Kim · Zhaolan Zhou · Zhaolan Zhou
ADAM10-mediated ephrin-B2 shedding promotes myofibroblast activation and organ fibrosis Anthony Letai · Anthony Letai
Functional precision cancer medicine[mdash]moving beyond pure genomics Elodie Bal · Hyun-Sook Park · Zakia Belaid-Choucair · Hülya Kayserili · Magali Naville · Marine Madrange · E. Chiticariu · S. Hadj-Rabia · Nicolas Cagnard · François Kuonen · Daniel Bachmann · Marcel Huber · Cindy Le Gall · Francine Côté · Sylvain Hanein · Rasim Ozgur Rosti · Ayca D. Aslanger · Quinten Waisfisz · C. Bodemer · Olivier Hermine · Fanny Morice-Picard · Bruno Labeille · F. Caux · J. Mazereeuw-Hautier · Nicole Philip · Nicolas Lévy · Alain Taïeb · Marie-Françoise Avril · Denis Headon · Gabor Gyapay · Thierry Magnaldo · Sylvie Fraitag · Hugues Roest Crollius · Pierre Vabres · Daniel Hohl · Arnold Munnich · Asma Smahi · Asma Smahi
Mutations in ACTRT1 and its enhancer RNA elements lead to aberrant activation of Hedgehog signaling in inherited and sporadic basal cell carcinomas Jason You · Kavitha Muralidharan · Jin W Park · Iraklis Petrof · Mark S. Pyfer · Brian Corbett · John J. LaFrancois · Yi Zheng · Xiaohong Zhang · Carrie A Mohila · Daniel Yoshor · Robert A Rissman · Eric J. Nestler · Helen E. Scharfman · Jeannie Chin · Jeannie Chin
代謝:マウスで見られるコレステロールの胆汁酸への低温誘導性の変換は腸のマイクロバイオームを適合させ,適応性熱産生を促進する Luigina Romani · Claudia Stincardini · Stefano Giovagnoli · Maurizio Paci · Valeria Rachela Villella · Luigi Sforna · Giorgia Renga · Marina Maria Bellet · Claudio Costantini · Paolo Puccetti · Guido Kroemer · Luigi Maiuri · Mauro Pessia · Allan L. Goldstein · Enrico Garaci · Enrico Garaci
Corrigendum: Classification and characterization of microsatellite instability across 18 cancer types Rodrigo Romero · Volkan I. Sayin · Shawn M. Davidson · Matthew R. Bauer · Simranjit X. Singh · Sarah LeBoeuf · Triantafyllia R. Karakousi · Donald Christian Ellis · Arjun Bhutkar · Francisco J. Sánchez-Rivera · Lakshmipriya Subbaraj · Britney Martinez · Roderick T. Bronson · Justin R. Prigge · Edward E. Schmidt · Craig J. Thomas · Chandra Goparaju · Angela M. Davies · Igor Dolgalev · Adriana Heguy · Viola Allaj · John T. Poirier · Andre L. Moreira · Charles M. Rudin · Harvey I. Pass · Matthew G. Vander Heiden · Tyler Jacks · Thales Papagiannakopoulos · Thales Papagiannakopoulos
HIV‐1:新規の解析法により明らかにされた,静止期CD4+T細胞中の誘導性で複製能を持つHIV‐1の大きなリザーバー Cliona M. Rooney · Tim Sauer · Tim Sauer
Long noncoding RNA EGFR-AS1 mediates epidermal growth factor receptor addiction and modulates treatment response in squamous cell carcinoma Sarah Weske · Mithila Vaidya · Alina Reese · Karin von Wnuck Lipinski · Petra Keul · Julia K Bayer · Jens W. Fischer · Ulrich Flögel · Jens Nelsen · Matthias Epple · Marta Scatena · Edzard Schwedhelm · Marcus Dörr · Henry Völzke · Eileen Moritz · Anke Hannemann · Bernhard Rauch · Markus H. Gräler · G. Heusch · Bodo Levkau · Bodo Levkau
A mouse model for embryonal tumors with multilayered rosettes uncovers the therapeutic potential of Sonic-hedgehog inhibitors Daniel S.W. Tan · Fui Teen Chong · Hui Sun Leong · Shen Yon Toh · Dawn Pingxi Lau · Xue Lin Kwang · Xiaoqian Zhang · Gopinath M. Sundaram · Gek San Tan · Mei Mei Chang · Boon Tin Chua · Wan Teck Lim · Eng Huat Tan · Mei Kim Ang · Tony Kiat Hon Lim · Prabha Sampath · Balram Chowbay · Anders Skanderup · Ramanuj DasGupta · N. Gopalakrishna Iyer · N. Gopalakrishna Iyer
Exhausting alloreactivity of donor-derived CAR T cells Christa E. Osuna · So-Yon Lim · Claire Deleage · Bryan D. Griffin · Derek R. Stein · Lukas T. Schroeder · Robert Omage · Katharine Best · Ma Luo · Peter Hraber · Hanne Andersen-Elyard · Erwing Fabian Cardozo Ojeda · Scott Huang · Dana L. Vanlandingham · Stephen Higgs · Alan S. Perelson · Jacob D. Estes · David Safronetz · Mark G. Lewis · James B. Whitney · James B. Whitney
心疾患:心‐脳‐腎ネットワークは組織マクロファージの活性化を介して心臓負荷への適応を制御している Fujiu Katsuhito · Shibata Munehiko · Nakayama Yukiteru · Ogata Fusa · Matsumoto Sahohime · Komuro Issei · Iwami Shingo · Nakae Susumu · Noshita Koji · Nagai Ryozo · Manabe Ichiro · Manabe Ichiro
Targeting mitochondrial dysfunction can restore antiviral activity of exhausted HBV-specific CD8 T cells in chronic hepatitis B Deborah M. Muoio · Deborah M. Muoio
Understanding cancer from the stem cells up Christopher A. Eide · Christopher A. Eide · Brian J. Druker · Brian J. Druker
Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids Fotios Sampaziotis · Alexander Justin · O Tysoe · Stephen J. Sawiak · Edmund Godfrey · Sara Upponi · Richard L. Gieseck · Miguel Cardoso de Brito · Natalie Lie Berntsen · María J Gómez-Vázquez · Daniel Ortmann · Loukia Yiangou · Alexander Ross · Johannes Bargehr · Alessandro Bertero · Mariëlle C. F. Zonneveld · Marianne Terndrup Pedersen · Matthias Pawlowski · Laura Valestrand · Pedro Madrigal · Nikitas Georgakopoulos · Negar Pirmadjid · Gregor Skeldon · John Casey · Wenmiao Shu · Paulina M Materek · Kirsten E. Snijders · Stephanie E. Brown · Casey Rimland · Ingrid Simonic · Susan E. Davies · Kim B Jensen · Matthias Zilbauer · W. Gelson · Graeme J. M. Alexander · Sanjay Sinha · Nicholas Hannan · Thomas A. Wynn · Tom H. Karlsen · Espen Melum · Ae Markaki · Kourosh Saeb-Parsy · Ludovic Vallier · Ludovic Vallier
Corrigendum: ADAM10-mediated ephrin-B2 shedding promotes myofibroblast activation and organ fibrosis Kesarwani Meenu · Kincaid Zachary · Gomaa Ahmed · Huber Erika · Rohrabaugh Sara · Siddiqui Zain · Bouso Muhammad F · Komurov Kakajan · Mulloy James C · Cancelas Jose A · Grimes H Leighton · Azam Mohammad · Latif Tahir · Xu Ming · Xu Ming
がん治療:c‐FOSおよびDUSP1のターゲッティングはBCR‐ABL白血病でチロシンキナーゼ阻害剤に対する内因性耐性を消失させる Katie A Fennell · Mark A. Dawson · Mark A. Dawson
Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing Miguel Crespo · Eduardo Vilar · Su-Yi Tsai · Su-Yi Tsai · Kyle Chang · Sadaf Amin · Tara Srinivasan · Tuo Zhang · Nina H. Pipalia · Huanhuan Joyce Chen · Mavee Witherspoon · Miriam Gordillo · Jenny Xiang · Frederick R. Maxfield · Steven M. Lipkin · Todd Evans · Shuibing Chen · Shuibing Chen
A tripartite complex of suPAR, APOL1 risk variants and αvβ3 integrin on podocytes mediates chronic kidney disease Salim Hayek · Kwi Hye Koh · Morgan E. Grams · Changli Wei · Yi An Ko · Jing Li · Beata Samelko · Hyun Lee · Ranadheer R. Dande · Ha Won Lee · Eunsil Hahm · Vasil Peev · Melissa Tracy · Nicholas J. Tardi · Vineet Gupta · Mehmet M. Altintas · Garrett Garborcauskas · Nikolina Stojanovic · Cheryl A. Winkler · Michael S. Lipkowitz · Adrienne Tin · Lesley A. Inker · Andrew S. Levey · Martin Zeier · Barry I. Freedman · Jeffrey B. Kopp · Karl Skorecki · Josef Coresh · Arshed A. Quyyumi · Sanja Sever · Jochen Reiser · Jochen Reiser
Interaction of reactive astrocytes with type I collagen induces astrocytic scar formation through the integrin–N-cadherin pathway after spinal cord injury Masamitsu Hara · Kazu Kobayakawa · Yasuyuki Ohkawa · Hiromi Kumamaru · Kazuya Yokota · Takeyuki Saito · Ken Kijima · Shingo Yoshizaki · Katsumi Harimaya · Yasuharu Nakashima · Seiji Okada · Seiji Okada
Fibroblast growth factor 19 regulates skeletal muscle mass and ameliorates muscle wasting in mice Bérengère Benoit · Martina Castelli · Stéphanie Chanon · Aurélie Vieille-Marchiset · Christine Durand · Nadia Bendridi · Sandra Pesenti · Pierre-Axel Monternier · Anne-Cécile Durieux · Damien Freyssenet · Jennifer Rieusset · Etienne Lefai · Hubert Vidal · Jérôme Ruzzin · Jérôme Ruzzin
Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling Daniel A. Giles · Maria E. Moreno-Fernandez · Traci E. Stankiewicz · Simon Graspeuntner · Monica Cappelletti · David Wu · Rajib Mukherjee · Calvin C. Chan · Matthew J. Lawson · Jared Klarquist · Annika Sünderhauf · Samir Softic · C. Ronald Kahn · Kerstin Stemmer · Yoichiro Iwakura · Bruce J. Aronow · Rebekah Karns · Kris A. Steinbrecher · Christopher L. Karp · Rachel Sheridan · Shiva Kumar Shanmukhappa · Damien Reynaud · David B Haslam · Christian Sina · Jan Rupp · Simon P. Hogan · Senad Divanovic · Senad Divanovic
Elimination of large tumors in mice by mRNA-encoded bispecific antibodies Christiane Stadler · Hayat Bähr-Mahmud · Leyla Celik · Bernhard Hebich · Alexandra S Roth · René P Roth · Katalin Karikó · Özlem Türeci · Ugur Sahin · Ugur Sahin
Gut microbiome and serum metabolome alterations in obesity and after weight-loss intervention Ruixin Liu · Jie Hong · Xiaoqiang Xu · Qiang Feng · Dongya Zhang · Yanyun Gu · Juan Shi · Shaoqian Zhao · Wen Liu · Xiaokai Wang · Huihua Xia · Zhipeng Liu · Bin Cui · Peiwen Liang · Liuqing Xi · Jiabin Jin · Xiayang Ying · Xiaolin Wang · Xinjie Zhao · Wanyu Li · Huijue Jia · Zhou Lan · Fengyu Li · R.Z. Wang · Yingkai Sun · Minglan Yang · Yuxin Shen · Zhuye Jie · Junhua Li · Xiaomin Chen · Huanzi Zhong · Hailiang Xie · Zhang Y · Weiqiong Gu · Xiaxing Deng · Baiyong Shen · Xun Xu · Huanming Yang · Guowang Xu · Yufang Bi · Shenghan Lai · Jian Wang · Lu Qi · Lu Qi · Lise Madsen · Lise Madsen · Jiqiu Wang · Guang Ning · Karsten Kristiansen · Weiqing Wang · Weiqing Wang
SPOP tips the balance of BETs in cancer Chuang Chen‐Hua · Rogers Zoee N · Brady Jennifer J · Chiou Shin‐Heng · Winters Aidan F · Gruener Barbara M · Ramaswami Gokul · Li Jin Billy · Kundaje Anshul · Winslow Monte M · Greenside Peyton G · Yang Dian · Caswell Deborah R · Spencley Andrew L · Sweet‐Cordero E Alejandro · Kopecky Kimberly E · Sayles Leanne C · Sayles Leanne C
転移段階にある肺がんの分子的特徴づけはCD109‐Janusキナーゼ‐Stat軸が治療標的候補であることを示している Carsten Linnemann · Marit M. van Buuren · Laura Bies · Els M. E. Verdegaal · Remko Schotte · Jorg J A Calis · Sam Behjati · Arno Velds · Henk Hilkmann · Dris El Atmioui · Marten Visser · Michael R. Stratton · John B. A. G. Haanen · Hergen Spits · Sjoerd H. van der Burg · Ton N. M. Schumacher · Ton N. M. Schumacher
Cold-induced conversion of cholesterol to bile acids in mice shapes the gut microbiome and promotes adaptive thermogenesis Anna Worthmann · Clara John · Malte C. Rühlemann · Miriam Baguhl · Femke-Anouska Heinsen · Nicola Schaltenberg · Markus Heine · Christian Schlein · Ioannis Evangelakos · Chieko Mineo · Markus Fischer · M. Dandri · Claus Kremoser · Ludger Scheja · Andre Franke · Philip W. Shaul · Joerg Heeren · Joerg Heeren
ISDoT: in situ decellularization of tissues for high-resolution imaging and proteomic analysis of native extracellular matrix Alejandro Mayorca-Guiliani · Chris D. Madsen · Thomas R. Cox · Edward R Horton · Freja Albjerg Venning · Janine T. Erler · Janine T. Erler
Source code: Putting metagenomics to the test in the clinic Carrie Arnold · Carrie Arnold
Corrigendum: SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia Constanze Schneider · Thomas Oellerich · Hanna-Mari Baldauf · Sarah-Marie Schwarz · Dominique Thomas · Robert Flick · Hanibal Bohnenberger · Lars Kaderali · Lena Stegmann · Anjali Cremer · Margarethe Martin · Julian Lohmeyer · Martin Michaelis · Veit Hornung · Christoph Schliemann · Wolfgang E. Berdel · Wolfgang Hartmann · Eva Wardelmann · Federico Comoglio · Martin-Leo Hansmann · Alexander F. Yakunin · Gerd Geisslinger · Philipp Ströbel · Nerea Ferreirós · Hubert Serve · Oliver T. Keppler · Jindrich Cinatl · Jindrich Cinatl
Viral vanguard: Designing cancer-killing viruses to chase metastatic tumors Shraddha Chakradhar · Shraddha Chakradhar
Fattening the role of Ca 2+ cycling in adaptive thermogenesis David Lagares · Parisa Ghassemi-Kakroodi · Caroline Tremblay · Alba Santos · Clemens K. Probst · Alicia Franklin · Daniela M Santos · Paula Grasberger · Neil Ahluwalia · Sydney B. Montesi · Barry S. Shea · Katharine E. Black · Rachel S. Knipe · Meryem Blati · Murray Baron · Brian Wu · Hassan Fahmi · Rajiv Gandhi · Annie Pardo · Moisés Selman · Jiangping Wu · Jean-Pierre Pelletier · Johanne Martel-Pelletier · Andrew M. Tager · Mohit Kapoor · Mohit Kapoor
A mouse model of renal cell carcinoma Laura S. Schmidt · W. Marston Linehan · W. Marston Linehan
An unexpected role for bile acid synthesis in adaptation to low temperature Folkert Kuipers · Albert K. Groen · Albert K. Groen
ドナーCD19CAR T細胞は強力な移植片対リンパ腫活性を発揮するが,移植片対宿主活性は減弱する Ghosh Arnab · Smith Melody · James Scott E · Velardi Enrico · Argyropoulos Kimon · Kreines Fabiana M · Levy Emily R · Lieberman Sophie · Jay Hillary · Tuckett Andrea Z · Tan Lisa · Young Lauren F · Takvorian Kate · Dudakov Jarrod A · Jenq Robert R · Hanash Alan M · Schietinger Andrea · Sadelain Michel · Van Den Brink Marcel R M · Davila Marco L · Gunset Gertrude · Perna Fabiana · Zakrzewski Johannes L · Motta Ana Carolina F · Murphy George F · Liu Chen · Liu Chen
脂質代謝:低温誘導性リポカイン12,13‐diHOMEは褐色脂肪組織への脂肪酸輸送を促進する Lynes Matthew D · Leiria Luiz O · Lundh Morten · Shamsi Farnaz · Huang Tian Lian · Takahashi Hirokazu · Hirshman Michael F · Goodyear Laurie J · Tseng Yu‐Hua · Bartelt Alexander · Schlein Christian · Lee Alexandra · Hotamisligil Goekhan S · Baer Lisa A · May Francis J · Stanford Kristin I · Gao Fei · Narain Niven R · Chen Emily Y · Kiebish Michael A · Cypess Aaron M · Blueher Matthias · Blueher Matthias
The missing pieces: Lack of Zika data from Africa complicates search for answers Nicole Wetsman · Nicole Wetsman
Resolving a chronic inflammation mystery Ben Roediger · Wolfgang Weninger · Wolfgang Weninger
システイナーゼ/シスチナーゼによるL‐システイン/シスチンの全身的枯渇は活性酸素種を増加させて腫瘍の増殖を抑制する Cramer Shira L · Triplett Kendra · Lamb Candice · Georgiou George · Saha Achinto · Digiovanni John · Liu Jinyun · Huang Peng · Tadi Surendar · Tiziani Stefano · Yan Wupeng · Zhang Yan Jessie · Stone Everett · Alters Susan E · Rowlinson Scott · Keating Michael J · Keating Michael J
A distinct innate lymphoid cell population regulates tumor-associated T cells P. Fisicaro · Valeria Barili · Barbara Montanini · Greta Acerbi · Manuela Ferracin · Francesca Guerrieri · Debora Salerno · Carolina Boni · Marco Massari · M Cristina Cavallo · G. Grossi · T. Giuberti · P. Lampertico · P. Lampertico · Gabriele Missale · Massimo Levrero · Massimo Levrero · Simone Ottonello · Carlo Ferrari · Carlo Ferrari
がん:幹細胞性に関連するZEB1‐MSRB3軸は細胞の適応性と乳がんゲノムの安定性を支配する Morel Anne‐Pierre · Pommier Roxane M · Ruiz Emmanuelle · Devouassoux‐Shisheboran Mojgan · Chassot Christelle · Pinatel Christiane · Fauvet Frederique · Saintigny Pierre · Moyret‐Lalle Caroline · Lachuer Joeel · Wierinckx Anne · Cox David G · Ansieau Stephane · Caramel Julie · Vigneron Arnaud M · Tissier Agnes · Puisieux Alain · Ginestier Christophe · Cabaud Olivier · Wicinski Julien · Finetti Pascal · Bertucci Francois · Birnbaum Daniel · Charafe‐Jauffret Emmanuelle · Combaret Valerie · Wang Qing · Thomas Emilie · Despras Emmanuelle · Jauffret Jean‐Luc · Guitton Jerome · Radosevic‐Robin Nina · Penault‐Llorca Frederique · Hollande Frederic · Hollande Frederic
A three-drug combination to treat BRAF -mutant cancers Ari J Firestone · Jeffrey Settleman · Jeffrey Settleman
Implications of human genetic variation in CRISPR-based therapeutic genome editing David Arthur Scott · Feng Zhang · Feng Zhang
Resolution of inflammation by interleukin-9-producing type 2 innate lymphoid cells Simon Rauber · Markus Luber · Stefanie Weber · Lisa Maul · Thomas Wohlfahrt · Neng-Yu Lin · Katharina Dietel · Aline Bozec · Martin Herrmann · Mark H. Kaplan · Benno Weigmann · Mario M. Zaiss · Ursula Fearon · Douglas J. Veale · Juan D. Cañete · Oliver Distler · Felice Rivellese · Costantino Pitzalis · Markus F. Neurath · Andrew N. J. McKenzie · Stefan Wirtz · Georg Schett · Jörg H W Distler · Andreas Ramming · Andreas Ramming
The eukaryotic gut virome in hematopoietic stem cell transplantation: new clues in enteric graft-versus-host disease Jérôme Legoff · Matthieu Resche-Rigon · Jerome Bouquet · Marie Robin · Samia N. Naccache · Séverine Mercier-Delarue · Scot Federman · Erik Samayoa · Clotilde Rousseau · Prescillia Piron · Nathalie Kapel · François Simon · Gérard Socié · Charles Y. Chiu · Charles Y. Chiu
D -mannose induces regulatory T cells and suppresses immunopathology Dunfang Zhang · Dunfang Zhang · Cheryl Chia · Xue Jiao · Xue Jiao · Wenwen Jin · Shimpei Kasagi · Ruiqing Wu · Ruiqing Wu · Joanne E. Konkel · Hiroko Nakatsukasa · Peter Zanvit · Nathan Goldberg · Qianming Chen · Lingyun Sun · Zi Jiang Chen · WanJun Chen · WanJun Chen
Insulin action and resistance in obesity and type 2 diabetes Michael P. Czech · Michael P. Czech
Inflammation-dependent cerebrospinal fluid hypersecretion by the choroid plexus epithelium in posthemorrhagic hydrocephalus Jason K. Karimy · Jinwei Zhang · David B. Kurland · Brianna Carusillo Theriault · Daniel Duran · Jesse A. Stokum · Charuta Gavankar Furey · Xu Zhou · M. Shahid mansuri · Julio Montejo · Alberto Vera · Michael L. DiLuna · Eric Delpire · Seth L. Alper · Murat Gunel · Volodymyr Gerzanich · Ruslan Medzhitov · J. Marc Simard · Kristopher T. Kahle · Kristopher T. Kahle
SNP-mediated disruption of CTCF binding at the IFITM3 promoter is associated with risk of severe influenza in humans E. Kaitlynn Allen · Adrienne G. Randolph · Tushar Bhangale · Pranay Dogra · Maikke B. Ohlson · Christine M Oshansky · Anthony E. Zamora · John P Shannon · David Finkelstein · Amy Dressen · John P. DeVincenzo · Miguela Caniza · Ben Youngblood · Carrie M. Rosenberger · Paul G. Thomas · Paul G. Thomas
Correction of a splicing defect in a mouse model of congenital muscular dystrophy type 1A using a homology-directed-repair-independent mechanism Dwi U. Kemaladewi · Eleonora Maino · Elzbieta Hyatt · Huayun Hou · Maylynn Ding · Kara M Place · Xinyi Zhu · Prabhpreet S Bassi · Zahra Baghestani · Amit G Deshwar · Daniele Merico · Hui Y. Xiong · Brendan J. Frey · Michael D. Wilson · Evgueni A. Ivakine · Ronald D. Cohn · Ronald D. Cohn
An approach to suppress the evolution of resistance in BRAFV600E-mutant cancer Yaohua Xue · Luciano G. Martelotto · Timour Baslan · Alberto Vides · Martha Solomon · Trang Thi Mai · Neelam Chaudhary · Greg Riely · Bob T. Li · Kerry Scott · Fabiola Cechhi · Ulrika Stierner · Kalyani Chadalavada · Elisa de Stanchina · Sarit Schwartz · Todd Hembrough · Gouri Nanjangud · Michael F. Berger · Jonas A. Nilsson · Scott W. Lowe · Jorge S. Reis-Filho · Neal Rosen · Piro Lito · Piro Lito
The cannabis paradox: when age matters Andrés Ozaita · Ester Aso · Ester Aso
Combined mutation in Vhl, Trp53 and Rb1 causes clear cell renal cell carcinoma in mice Sabine Harlander · Désirée Schönenberger · Nora C. Toussaint · Michael Prummer · Antonella Catalano · Laura P. Brandt · Holger Moch · Peter Wild · Ian J. Frew · Ian J. Frew
Calculated risk: a new single-nucleotide polymorphism linked to severe influenza disease Amie J. Eisfeld · Yoshihiro Kawaoka · Yoshihiro Kawaoka
Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug Hao Wu · Eduardo Esteve · Valentina Tremaroli · Muhammad Tanweer Khan · Robert Caesar · Louise Mannerås-Holm · Marcus Ståhlman · Lisa M Olsson · Matteo Serino · Mercè Planas-Fèlix · Josep M. Mercader · David Torrents · Rémy Burcelin · Wifredo Ricart · Rosie Perkins · José Manuel Fernández-Real · Fredrik Bäckhed · Fredrik Bäckhed
Marginal zone B cells control the response of follicular helper T cells to a high-cholesterol diet Meritxell Nus · Andrew P. Sage · Yuning Lu · Leanne Masters · Brian Yee Hong Lam · Stephen A. Newland · Sandra Weller · Dimitrios Tsiantoulas · Juliette Raffort · Damiënne Marcus · Alison Finigan · Lauren Kitt · Nichola Figg · Reinhold Schirmbeck · Manfred Kneilling · Giles S. H. Yeo · Christoph J. Binder · José Luis de la Pompa · Ziad Mallat · Ziad Mallat
Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance Donnele Daley · Vishnu R. Mani · Navyatha Mohan · Neha Akkad · Atsuo Ochi · Daniel W. Heindel · Ki Buom Lee · Constantinos P. Zambirinis · Gautam Sd Balasubramania Pandian · Shivraj Savadkar · Alejandro Torres-Hernandez · Shruti Nayak · Ding Wang · Mautin Hundeyin · Brian Diskin · Berk Aykut · Gregor Werba · Rocky Barilla · Robert Rodriguez · Steven Y. Chang · Lawrence Gardner · Lara K. Mahal · Beatrix Ueberheide · George Miller · George Miller
A curious connection: Teasing apart the link between gut microbes and lung disease Shraddha Chakradhar · Shraddha Chakradhar
Erratum: Reply toNeutrophils are not required for resolution of acute gouty arthritis in mice Christiane Reinwald · Christine Schauer · Janka Zsófia Csepregi · Deborah Kienhöfer · Daniela Weidner · Marie Malissen · Attila Mócsai · Georg Schett · Martin J. Herrmann · Markus Hoffmann · Markus Hoffmann
Refining strategies to translate genome editing to the clinic Tatjana I. Cornu · Claudio Mussolino · Toni Cathomen · Toni Cathomen
Autoimmune T cell recognition of alternative-reading-frame-encoded peptides Jiajie Wei · Jonathan W. Yewdell · Jonathan W. Yewdell
Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor–neutralizing therapy in patients with inflammatory bowel disease Nathaniel R. West · Ahmed N. Hegazy · Owens Bmj. · Samuel J. Bullers · B Linggi · Sofia Buonocore · M Coccia · D Görtz · S This · K Stockenhuber · Johanna Pott · M Friedrich · Grigory Ryzhakov · F Baribaud · C Brodmerkel · C Cieluch · Nahid Rahman · G Müller-Newen · Raymond J. Owens · A A Kühl · Kevin J. Maloy · S E Plevy · Satish Keshav · Travis Spl. · Fiona Powrie · Fiona Powrie
Untangling the role of mutant histone H3 in diffuse intrinsic pontine glioma Caretha L Creasy · Caretha L Creasy
The Drug Repurposing Hub: a next-generation drug library and information resource Steven M. Corsello · Joshua Bittker · Zihan Liu · Joshua Gould · Patrick McCarren · Jodi E. Hirschman · Stephen Johnston · Anita Vrcic · Bang Wong · Mariya Khan · Jacob K. Asiedu · Rajiv Narayan · Christopher Mader · Aravind Subramanian · Todd R. Golub · Todd R. Golub
A mouse recapitulating APOL1-associated kidney disease Cheryl A. Winkler · George W. Nelson · George W. Nelson
Beyond the breath: Exploring sex differences in tuberculosis outside the lungs Alla Katsnelson · Alla Katsnelson
PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer Fara Brasó-Maristany · Filosto S · Catchpole S · Rebecca Marlow · Jelmar Quist · Erika Francesch-Domenech · Plumb Da · Zakka L · Patrycja Gazinska · Gianmaria Liccardi · Pascal Meier · Gris-Oliver A · Maggie Cheang · Perdrix-Rosell A · Shafat M · Elodie Noel · Nirmesh Patel · McEachern K · Maurizio Scaltriti · Pau Castel · Farzana Noor · Richard Buus · Sumi Mathew · Johnathan Watkins · Serra · Pierfrancesco Marra · Anita Grigoriadis · Andrew Tutt · Andrew Tutt
Inflammatory illness: Why the next wave of antidepressants may target the immune system Shiri Gur-Cohen · Tomer Itkin · Sagarika Chakrabarty · Claudine Graf · Orit Kollet · Aya Ludin · Karin Golan · Alexander Kalinkovich · Guy Ledergor · Eitan Wong · Elisabeth Niemeyer · Ziv Porat · Ayelet Erez · Irit Sagi · Charles T. Esmon · Wolfram Ruf · Tsvee Lapidot · Tsvee Lapidot
インプリンティング異常症:ヒストンメチルトランスフェラーゼG9aの標的化はインプリントされた遺伝子を活性化し,プラダー・ウィリー症候群マウスモデルの生存を改善する Furman David · Davis Mark M · Chang Junlei · Kuo Calvin J · Lartigue Lydia · Bolen Christopher R · Gaudilliere Brice · Ganio Edward A · Fragiadakis Gabriela K · Spitzer Matthew H · Nolan Garry P · Haddad Francois · Douchet Isabelle · Daburon Sophie · Moreau Jean-Francois · Blanco Patrick · Dechanet‐Merville Julie · Faustin Benjamin · Dekker Cornelia L · Jojic Vladimir · Jojic Vladimir
特定のインフラマソーム遺伝子モジュールの発現によって,高齢者は二極的な臨床的・免疫的状態に分類される Michael W. Salter · Beth Stevens · Beth Stevens
Microglia emerge as central players in brain disease Shraddha Chakradhar · Shraddha Chakradhar
Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure Stephanus T. Malherbe · Shubhada Shenai · Katharina Ronacher · Andre G. Loxton · Gregory Dolganov · Magdalena Kriel · Tran Van · Ray Y. Chen · James Warwick · Laura E. Via · Taeksun Song · Myungsun Lee · Gary K. Schoolnik · Gerard Tromp · David Alland · Clifton E. Barry · Jill Winter · Gerhard Walzl · Gerhard Walzl
Alternatively activated macrophages do not synthesize catecholamines or contribute to adipose tissue adaptive thermogenesis Katrin Fischer · Henry H. Ruiz · Kevin Jhun · Brian Finan · Douglas J. Oberlin · Verena van der Heide · Anastasia V. Kalinovich · Natasa Petrovic · Yochai Wolf · Christoffer Clemmensen · Andrew C. Shin · Andrew C. Shin · Senad Divanovic · Frank Brombacher · Elke Glasmacher · Susanne Keipert · Martin Jastroch · Joachim Nagler · Karl-Werner Schramm · Dasa Medrikova · Gustav Colldén · Stephen C. Woods · Stephan Herzig · Dirk Homann · Steffen Jung · Jan Nedergaard · Barbara Cannon · Matthias H. Tschöp · Timo D. Müller · Christoph Buettner · Christoph Buettner
A stemness-related ZEB1-MSRB3 axis governs cellular pliancy and breast cancer genome stability Anne-Pierre Morel · Christophe Ginestier · Roxane Pommier · Olivier Cabaud · Emmanuelle Ruiz · Julien Wicinski · Mojgan Devouassoux-Shisheboran · Valérie Combaret · Pascal Finetti · Christelle Chassot · Christiane Pinatel · Frédérique Fauvet · Pierre Saintigny · Emilie Thomas · Caroline Moyret-Lalle · Joël Lachuer · Emmanuelle Despras · Jean-Luc Jauffret · François Bertucci · Jérôme Guitton · Anne Wierinckx · Qing Wang · Nina Radosevic-Robin · Frédérique Penault-Llorca · David G. Cox · Frédéric Hollande · Stéphane Ansieau · Julie Caramel · Daniel Birnbaum · Arnaud Vigneron · Agnès Tissier · Emmanuelle Charafe-Jauffret · Alain Puisieux · Alain Puisieux
HIV persistence in tissue macrophages of humanized myeloid-only mice during antiretroviral therapy Jenna B. Honeycutt · William O. Thayer · Caroline E. Baker · Ruy M. Ribeiro · Steven M. Lada · Youfang Cao · Rachel Cleary · Michael G. Hudgens · Douglas D. Richman · J. Victor Garcia · J. Victor Garcia
A chronic low dose of [Delta]9-tetrahydrocannabinol (THC) restores cognitive function in old mice Andras Bilkei-Gorzo · Onder Albayram · Astrid Draffehn · Kerstin Michel · Anastasia Piyanova · Hannah Oppenheimer · Mona Dvir-Ginzberg · Ildiko Racz · Thomas Ulas · Sophie Imbeault · Itai Bab · Joachim L. Schultze · Andreas Zimmer · Andreas Zimmer
Novel assay reveals a large, inducible, replication-competent HIV-1 reservoir in resting CD4 + T cells Anwesha Sanyal · Robbie B. Mailliard · Charles R. Rinaldo · Deena Ratner · Ming Ding · Yue Chen · Jennifer M. Zerbato · Nicholas S. Giacobbi · Narasimhan J. Venkatachari · Bruce K. Patterson · Amanda Chargin · Nicolas Sluis-Cremer · Phalguni Gupta · Phalguni Gupta
Metformin ameliorates core deficits in a mouse model of fragile X syndrome Ilse Gantois · Arkady Khoutorsky · Jelena Popic · Argel Aguilar-Valles · Argel Aguilar-Valles · Erika Freemantle · Ruifeng Cao · Vijendra Sharma · Tine Pooters · Anmol Nagpal · Agnieszka Skalecka · Vinh Tai Truong · Shane Wiebe · Isabelle Groves · Seyed Mehdi Jafarnejad · Clément Chapat · Elizabeth A. McCullagh · Karine Gamache · Karim Nader · Jean Claude Lacaille · Christos G. Gkogkas · Nahum Sonenberg · Nahum Sonenberg
Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia Alice Giustacchini · Supat Thongjuea · Nikolaos Barkas · Petter S. Woll · Benjamin Povinelli · C Booth · P. Sopp · Ruggiero Norfo · Alba Rodriguez-Meira · Neil Ashley · Lauren Jamieson · Paresh Vyas · Kristina Anderson · Åsa Segerstolpe · Hong Qian · Ulla Olsson-Strömberg · Satu Mustjoki · Rickard Sandberg · Sten Eirik W. Jacobsen · Adam Mead · Adam Mead
Decreased alertness due to sleep loss increases pain sensitivity in mice Chloe Alexandre · Alban Latremoliere · Ashley Ferreira · Giulia Miracca · Mihoko Yamamoto · Thomas E. Scammell · Clifford J. Woolf · Clifford J. Woolf
CX3CR1+ monocytes modulate learning and learning-dependent dendritic spine remodeling via TNF-[alpha] Juan Mauricio Garré · Hernandez Moura Silva · Juan J. Lafaille · Guang Yang · Guang Yang
Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients Ahmet Zehir · Ryma Benayed · Ronak Shah · Aijazuddin Syed · Sumit Middha · Hyunjae R. Kim · Preethi Srinivasan · Jianjiong Gao · Debyani Chakravarty · Sean M. Devlin · Matthew D. Hellmann · David Barron · Alison M. Schram · Meera Hameed · Snjezana Dogan · Dara S. Ross · Jaclyn F. Hechtman · Deborah DeLair · Jinjuan Yao · Diana Mandelker · Donavan T. Cheng · Raghu Chandramohan · Abhinita Mohanty · Ryan Ptashkin · Gowtham Jayakumaran · Meera Prasad · Mustafa H Syed · Anoop Balakrishnan Rema · Zhen Y Liu · Khedoudja Nafa · Laetitia Borsu · Justyna Sadowska · Jacklyn Casanova · Ruben Bacares · Iwona J Kiecka · Anna Razumova · Julie B Son · Lisa Stewart · Tessara Baldi · Kerry A Mullaney · Hikmat Al-Ahmadie · Efsevia Vakiani · Adam Abeshouse · Alexander Penson · Philip Jonsson · Niedzica Camacho · Matthew T. Chang · Helen H. Won · Benjamin E. Gross · Ritika Kundra · Zachary J. Heins · Hsiao-Wei Chen · Sarah Phillips · Hongxin Zhang · Jiaojiao Wang · Angelica Ochoa · Jonathan Wills · Michael Eubank · Stacy B Thomas · Stuart M Gardos · Dalicia Reales · Jesse Galle · Robert Durany · Roy Cambria · Wassim Abida · Andrea Cercek · Darren R. Feldman · Mrinal M. Gounder · A. Ari Hakimi · James J. Harding · Gopa Iyer · Yelena Y. Janjigian · Emmet Jordan · Ciara M Kelly · Maeve Aine Lowery · Luc G. T. Morris · Antonio Omuro · Nitya Raj · Pedram Razavi · Alexander N. Shoushtari · Neerav Shukla · Tara Soumerai · Anna M. Varghese · Rona Yaeger · Jonathan A. Coleman · Bernard H. Bochner · Gregory J. Riely · Leonard Saltz · Howard I. Scher · Paul Sabbatini · Mark E. Robson · David S. Klimstra · Barry S. Taylor · José Baselga · Nikolaus Schultz · David M. Hyman · Maria E. Arcila · David B. Solit · Marc Ladanyi · Michael F. Berger · Michael F. Berger
Tmbim1 is a multivesicular body regulator that protects against non-alcoholic fatty liver disease in mice and monkeys by targeting the lysosomal degradation of Tlr4 Guang-Nian Zhao · Peng Zhang · Jun Gong · Xiao-Jing Zhang · Pi-Xiao Wang · Miao Yin · Zhou Jiang · Li-Jun Shen · Yan-Xiao Ji · Jingjing Tong · Yutao Wang · Qiao-Fang Wei · Yong Wang · Xueyong Zhu · Xin Zhang · Jing Fang · Qingguo Xie · Zhi-Gang She · Zhihua Wang · Zan Huang · Hongliang Li · Hongliang Li
Thymosin [alpha]1: a single drug with multiple targets in cystic fibrosis André M. Cantin · John W. Hanrahan · John W. Hanrahan
A heart-brain-kidney network controls adaptation to cardiac stress through tissue macrophage activation Katsuhito Fujiu · Munehiko Shibata · Yukiteru Nakayama · Fusa Ogata · Sahohime Matsumoto · Koji Noshita · Shingo Iwami · Susumu Nakae · Issei Komuro · Ryozo Nagai · Ichiro Manabe · Ichiro Manabe
Pericytes impair capillary blood flow and motor function after chronic spinal cord injury Yaqing Li · Ana M. Lucas-Osma · Sophie Black · Mischa V. Bandet · Marilee J. Stephens · Romana Vavrek · Leo Sanelli · Keith K. Fenrich · Antonio Di Narzo · Stella Dracheva · Ian R. Winship · Karim Fouad · David J. Bennett · David J. Bennett
A role for oncostatin M in inflammatory bowel disease Walter M Kim · Arthur Kaser · Richard S. Blumberg · Richard S. Blumberg
Host DNA released by NETosis promotes rhinovirus-induced type-2 allergic asthma exacerbation Marie Toussaint · David J. Jackson · Dawid Swieboda · Anabel Guedán · Theodora-Dorita Tsourouktsoglou · Yee Man Ching · Coraline Radermecker · Heidi Makrinioti · Julia Aniscenko · Michael R. Edwards · Roberto Solari · Frédéric Farnir · Venizelos Papayannopoulos · Fabrice Bureau · Thomas Marichal · Sebastian L. Johnston · Sebastian L. Johnston
Host with the most: Targeting host cells instead of pathogens to fight infectious disease Amanda B. Keener · Amanda B. Keener
Bringing RNA into the fold: Small molecules find new targets in RNA to combat disease Shraddha Chakradhar · Shraddha Chakradhar
Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment Ok Hee Jeon · Chaekyu Kim · Chaekyu Kim · Remi Martin Laberge · Marco Demaria · Marco Demaria · Sona Rathod · Alain Philippe Vasserot · Jae Wook Chung · Do Hun Kim · Yan Poon · Nathaniel David · Darren J. Baker · Jan M. van Deursen · Judith Campisi · Judith Campisi · Jennifer H. Elisseeff · Jennifer H. Elisseeff
Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction Weier Qi · Hillary A. Keenan · Qian Li · Atsushi Ishikado · Aimo Kannt · Thorsten Sadowski · Mark A. Yorek · I-Hsien Wu · Samuel M. Lockhart · Lawrence J. Coppey · Anja Pfenninger · Chong Wee Liew · Guifen Qiang · Guifen Qiang · Alison Burkart · Stephanie M. Hastings · David M. Pober · Christopher Cahill · Monika A. Niewczas · William J. Israelsen · Liane J. Tinsley · Isaac E. Stillman · Peter S. Amenta · Edward P. Feener · Matthew G. Vander Heiden · Robert Stanton · George L. King · George L. King
lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/β-catenin signaling Nicolas Huot · Béatrice Jacquelin · Thalia Garcia-Tellez · Philippe Rascle · Mickaël J.-Y. Ploquin · Yoann Madec · R. Keith Reeves · Nathalie Derreudre-Bosquet · Michaela Müller-Trutwin · Michaela Müller-Trutwin
Antimalarial drug resistance: linking Plasmodium falciparum parasite biology to the clinic Benjamin Blasco · Didier Leroy · David A. Fidock · David A. Fidock
肝疾患:Tmbim1は多胞体調節因子であり,リソソームでのTlr4の分解を標的としてマウスやサルの非アルコール性脂肪性肝の発症を防止する Zhao Guangnian · Zhang Peng · Ji Yanxiao · Li Hongliang · Gong Jun · Zhang Xiao‐Jing · Wang Pixiao · Yin Miao · Jiang Zhou · Shen Li‐Jun · Tong Jingjing · Wang Yutao · Wei Qiao‐Fang · Zhu Xue‐Yong · Zhang Xin · She Zhigang · Wang Zhihua · Huang Zan · Wang Yong · Fang Jing · Xie Qingguo · Xie Qingguo
UCP1-independent signaling involving SERCA2b-mediated calcium cycling regulates beige fat thermogenesis and systemic glucose homeostasis Terry J. Fry · Nirali N. Shah · Rimas J. Orentas · Maryalice Stetler-Stevenson · Constance Yuan · Sneha Ramakrishna · Pamela L. Wolters · Staci Martin · Cindy Delbrook · Bonnie Yates · Haneen Shalabi · Thomas J. Fountaine · Jack F. Shern · Robbie G. Majzner · David F. Stroncek · Marianna Sabatino · Yang Feng · Dimiter S. Dimitrov · Ling Zhang · Sang Nguyen · Haiying Qin · Boro Dropulic · Daniel W. Lee · Crystal L. Mackall · Crystal L. Mackall
Corrigendum: Host DNA released by NETosis promotes rhinovirus-induced type-2 allergic asthma exacerbation Allan McI. Mowat · Charlotte L. Scott · Charlotte L. Scott · Calum C. Bain · Calum C. Bain
Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors Christa E. Osuna · So-Yon Lim · Claire Deleage · Bryan D. Griffin · Derek R. Stein · Lukas T. Schroeder · Robert W. Omange · Katharine Best · Ma Luo · Peter Hraber · Hanne Andersen-Elyard · Erwing Fabian Cardozo Ojeda · Scott Huang · Dana L. Vanlandingham · Stephen Higgs · Alan S. Perelson · Jacob D. Estes · David Safronetz · Mark G. Lewis · James B. Whitney · James B. Whitney
A chikungunya fever vaccine utilizing an insect-specific virus platform Shawn M. Davidson · Oliver Jonas · Mark A. Keibler · Han Wei Hou · Alba Luengo · Jared R. Mayers · Jeffrey Wyckoff · Amanda M. Del Rosario · Matthew Whitman · Christopher R. Chin · Kendall Janine Condon · Alex Lammers · Katherine A Kellersberger · Brian K Stall · Gregory Stephanopoulos · Dafna Bar-Sagi · Jongyoon Han · Joshua D. Rabinowitz · Michael J. Cima · Robert Langer · Matthew G. Vander Heiden · Matthew G. Vander Heiden
Fasting selectively blocks development of acute lymphoblastic leukemia via leptin-receptor upregulation Jesse H. Erasmus · Albert J. Auguste · Jason T. Kaelber · Huanle Luo · Shannan L. Rossi · Karla A. Fenton · Grace Leal · Dal Young Kim · Wah Chiu · Tian Wang · Ilya Frolov · Farooq Nasar · Scott C. Weaver · Scott C. Weaver
Dissociation of muscle insulin sensitivity from exercise endurance in mice by HDAC3 depletion Zhigang Lu · Jingjing Xie · Guojin Wu · Jinhui Shen · Robert H. Collins · Weina Chen · Xunlei Kang · Min Luo · Yizhou Zou · Lily Jun Shen Huang · James F. Amatruda · Tamra Slone · Naomi J. Winick · Philipp E. Scherer · Cheng Cheng Zhang · Cheng Cheng Zhang
SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia Sungguan Hong · Wenjun Zhou · Bin Fang · Wenyun Lu · Emanuele Loro · Manashree Damle · Guolian Ding · Jennifer Jager · Sisi Zhang · Yuxiang Zhang · Dan Feng · Qingwei Chu · Brian D. Dill · Henrik Molina · Tejvir S. Khurana · Joshua D. Rabinowitz · Mitchell A. Lazar · Zheng Sun · Zheng Sun
Interleukin-33-induced expression of PIBF1 by decidual B cells protects against preterm labor Constanze Schneider · Thomas Oellerich · Hanna-Mari Baldauf · Sarah-Marie Schwarz · Dominique Thomas · Robert Flick · Hanibal Bohnenberger · Lars Kaderali · Lena Stegmann · Anjali Cremer · Margarethe Martin · Julian Lohmeyer · Martin Michaelis · Veit Hornung · Christoph Schliemann · Wolfgang E. Berdel · Wolfgang Hartmann · Eva Wardelmann · Federico Comoglio · Martin-Leo Hansmann · Alexander F. Yakunin · Gerd Geisslinger · Philipp Ströbel · Nerea Ferreirós · Hubert Serve · Oliver T. Keppler · Jindrich Cinatl · Jindrich Cinatl
Dickkopf-1 promotes hematopoietic regeneration via direct and niche-mediated mechanisms Bihui Huang · Azure N. Faucette · Michael D Pawlitz · Bo Pei · Joshua W Goyert · Jordan Z. Zhou · Nadim G El-Hage · Jie Deng · Jason Lin · Fayi Yao · Robert S Dewar · Japnam S Jassal · Maxwell L Sandberg · Jing Dai · Montserrat Cols · Cong Shen · Lisa A Polin · Ronald A. Nichols · Theodore B. Jones · Martin H. Bluth · Karoline S. Puder · Bernard Gonik · Nihar R. Nayak · Elizabeth E. Puscheck · Wei-Zen Wei · Andrea Cerutti · Marco Colonna · Kang Chen · Kang Chen
Barrier-tissue macrophages: functional adaptation to environmental challenges Paul Maciocia · Patrycja A Wawrzyniecka · Brian Philip · Ida Ricciardelli · Ayse U. Akarca · Shimobi Onuoha · Mateusz Legut · David K. Cole · Andrew K. Sewell · Giuseppe Gritti · Joan Somja · Miguel A Piris · Karl S. Peggs · David C. Linch · Teresa Marafioti · Martin Pule · Martin Pule
Resting-state connectivity biomarkers define neurophysiological subtypes of depression Richard J. Webby · Richard J. Webby
Targeting the T cell receptor β-chain constant region for immunotherapy of T cell malignancies Joshua N. Farr · Ming Xu · Megan M. Weivoda · David G. Monroe · Daniel G. Fraser · Jennifer L Onken · Brittany A Negley · Jad G. Sfeir · Mikolaj Ogrodnik · Christine M Hachfeld · Nathan K. LeBrasseur · Matthew T. Drake · Robert J. Pignolo · Tamar Pirtskhalava · Tamara Tchkonia · Merry Jo Oursler · James L. Kirkland · Sundeep Khosla · Sundeep Khosla
Corrigendum: Targeting cellular senescence prevents age-related bone loss in mice Naoki Hosen · Yukiko Matsunaga · Yukiko Matsunaga · Kana Hasegawa · Hiroshi Matsuno · Yuki Nakamura · Mio Makita · Kouki Watanabe · Mikako Yoshida · Kei Satoh · Soyoko Morimoto · Fumihiro Fujiki · Hiroko Nakajima · Jun Nakata · Sumiyuki Nishida · Akihiro Tsuboi · Yoshihiro Oka · Masahiro Manabe · Hiroyoshi Ichihara · Yasutaka Aoyama · Atsuko Mugitani · Takafumi Nakao · Masayuki Hino · Ryosuke Uchibori · Keiya Ozawa · Keiya Ozawa · Yoshihiro Baba · Seitaro Terakura · Naoki Wada · Eiichi Morii · Junichi Nishimura · Kiyoshi Takeda · Yusuke Oji · Haruo Sugiyama · Junichi Takagi · Atsushi Kumanogoh · Atsushi Kumanogoh
The activated conformation of integrin β7 is a novel multiple myeloma-specific target for CAR T cell therapy Clemens Duerrschmid · Yanlin He · Chunmei Wang · Chia Li · Juan C. Bournat · Chase Romere · Pradip K. Saha · Mark E. Lee · Kevin J. Phillips · Mahim Jain · Peilin Jia · Zhongming Zhao · Monica Farias · Qi Wu · Dianna M. Milewicz · V. Reid Sutton · David D. Moore · Nancy F. Butte · Michael J. Krashes · Yong Xu · Atul R. Chopra · Atul R. Chopra
免疫:CX3CR1+単球は学習と学習依存的でTNF‐αを介する樹状突起棘リモデリングを変化させる West Nathaniel R · Hegazy Ahmed N · Bullers Samuel J · Stockenhuber Krista · Friedrich Matthias · Ryzhakov Grigory · Powrie Fiona · This Sebastien · Arancibia Carolina · Bailey Adam · Barnes Ellie · Bird‐Lieberman Beth · Brain Oliver · Braden Barbara · East James · Keshav Satish · Klenerman Paul · Leedham Simon · Simmons Alison · Travis Simon P L · Uhlig Holm · Owens Benjamin M J · Linggi Bryan · Baribaud Frederic · Brodmerkel Carrie · Plevy Scott E · Buonocore Sofia · Coccia Margherita · Pott Johanna · Maloy Kevin J · Goertz Dieter · Mueller‐Newen Gerhard · Cieluch Constanze · Kuehl Anja A · Rahman Nahid · Owens Raymond J · Collier Jane · Howarth Lucy · Palmer Rebecca · Rodrigues Astor · Sullivan Peter · Sullivan Peter
Long-range hypoxia signaling in NAFLD Kevin R. King · Aaron D. Aguirre · Yu-Xiang Ye · Yuan Sun · Jason D. Roh · Richard Patrick Ng · Rainer H. Kohler · Sean P. Arlauckas · Yoshiko Iwamoto · Andrej J. Savol · Ruslan I. Sadreyev · Mark Kelly · Timothy P. Fitzgibbons · Katherine A. Fitzgerald · Timothy J. Mitchison · Peter Libby · Matthias Nahrendorf · Ralph Weissleder · Ralph Weissleder
IRF3 and type I interferons fuel a fatal response to myocardial infarction Motoharu Awazawa · Paula Gabel · Eva Tsaousidou · Hendrik Nolte · Marcus Krüger · Joel Schmitz · P. Justus Ackermann · Claus Brandt · Janine Altmüller · Susanne Motameny · F. Thomas Wunderlich · Jan-Wilhelm Kornfeld · Matthias Blüher · Jens C. Brüning · Jens C. Brüning
A microRNA screen reveals that elevated hepatic ectodysplasin A expression contributes to obesity-induced insulin resistance in skeletal muscle Nagaraj Kerur · Shinichi Fukuda · Daipayan Banerjee · Younghee Kim · Dongxu Fu · Ivana Apicella · Akhil Varshney · Reo Yasuma · Benjamin J. Fowler · Elmira Baghdasaryan · Kenneth M. Marion · Xiwen Huang · Tetsuhiro Yasuma · Yoshio Hirano · Vlad Serbulea · Meenakshi Ambati · Vidya L Ambati · Yuji Kajiwara · Kameshwari Ambati · Shuichiro Hirahara · Ana Bastos-Carvalho · Yuichiro Ogura · Hiroko Terasaki · Tetsuro Oshika · Kyung Bo Kim · David R. Hinton · Norbert Leitinger · John C. Cambier · Joseph D. Buxbaum · M. Cristina Kenney · S. Michal Jazwinski · Hiroshi Nagai · Isao Hara · A. Phillip West · Katherine A. Fitzgerald · Srinivas R. Sadda · Bradley D. Gelfand · Jayakrishna Ambati · Jayakrishna Ambati
Targeting the histone methyltransferase G9a activates imprinted genes and improves survival of a mouse model of Prader-Willi syndrome Stefanie Göllner · Thomas Oellerich · Thomas Oellerich · Shuchi Agrawal-Singh · Tino Schenk · Hans-Ulrich Klein · Hans-Ulrich Klein · Christian Rohde · Caroline Pabst · Tim Sauer · Tim Sauer · Mads Lerdrup · Sigal Tavor · Friedrich Stölzel · Sylvia Herold · Gerhard Ehninger · Gabriele Köhler · Gabriele Köhler · Kuan Ting Pan · Henning Urlaub · Henning Urlaub · Hubert Serve · Hubert Serve · Martin Dugas · Karsten Spiekermann · Karsten Spiekermann · Binje Vick · Irmela Jeremias · Wolfgang E. Berdel · Klaus Hansen · Arthur Zelent · Claudia Wickenhauser · Lutz P. Müller · Christian Thiede · Carsten Müller-Tidow · Carsten Müller-Tidow
Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia Amy Maxmen · Amy Maxmen
Living therapeutics: Scientists genetically modify bacteria to deliver drugs Nikolas Herold · Sean G. Rudd · Linda Ljungblad · Kumar Sanjiv · Ida Hed Myrberg · Cynthia B.J. Paulin · Yaser Heshmati · Anna Hagenkort · Juliane Kutzner · Brent D. G. Page · José Manuel Calderón-Montaño · Olga Loseva · Ann-Sofie Jemth · Lorenzo Bulli · Hanna Axelsson · Bianca Tesi · Nicholas C. K. Valerie · Andreas Höglund · Julia Bladh · Elisee Wiita · Mikael Sundin · Michael Uhlin · Georgios Rassidakis · Mats Heyman · Katja Pokrovskaja Tamm · Ulrika Warpman-Berglund · Julian Walfridsson · Sören Lehmann · Dan Grandér · Thomas Lundbäck · Per Kogner · Jan-Inge Henter · Thomas Helleday · Torsten Schaller · Torsten Schaller
Macrophages dispose of catecholamines in adipose tissue Marie Toussaint · David J. Jackson · Dawid Swieboda · Anabel Guedán · Theodora-Dorita Tsourouktsoglou · Yee Man Ching · Coraline Radermecker · Heidi Makrinioti · Julia Aniscenko · Michael R. Edwards · Roberto Solari · Frédéric Farnir · Venizelos Papayannopoulos · Fabrice Bureau · Thomas Marichal · Sebastian L. Johnston · Sebastian L. Johnston
Blocking microglial pannexin-1 channels alleviates morphine withdrawal in rodents Crome Sq · Linh T. Nguyen · Sandra Lopez-Verges · Yang Sy · Martin B · Yam Jy · Johnson Dj · Nie J · Pniak M · Yen Ph · Milea A · Sowamber R · Katz · Marcus Q. Bernardini · Blaise Clarke · Patricia Shaw · Philipp A. Lang · Hal K. Berman · Trevor J. Pugh · Lewis L. Lanier · Pamela S. Ohashi · Pamela S. Ohashi
Maturation of the infant microbiome community structure and function across multiple body sites and in relation to mode of delivery Nicole E. Burma · Robert P. Bonin · Heather Leduc-Pessah · Corey Baimel · Zoe F Cairncross · Michael Mousseau · Jhenkruthi Vijaya Shankara · Patrick L. Stemkowski · Dinara V. Baimoukhametova · Jaideep S. Bains · Michael C. Antle · Gerald W. Zamponi · Catherine M. Cahill · Stephanie L. Borgland · Yves De Koninck · Tuan Trang · Tuan Trang
DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma Derrick Chu · Jun Ma · Amanda Prince · Kathleen Antony · Maxim D. Seferovic · Kjersti Aagaard · Kjersti Aagaard
JNK1 negatively controls antifungal innate immunity by suppressing CD23 expression Nathan C. Sheffield · Gaëlle Pierron · Johanna Klughammer · Paul Datlinger · Andreas Schönegger · Michael Schuster · Johanna Hadler · Didier Surdez · Delphine Guillemot · Eve Lapouble · Paul Fréneaux · Jacqueline Champigneulle · Raymonde Bouvier · Diana Walder · Ingeborg M. Ambros · Caroline Hutter · Eva Sorz · Ana Teresa Amaral · Enrique de Alava · Katharina Schallmoser · Dirk Strunk · Beate Rinner · Bernadette Liegl-Atzwanger · Berthold Huppertz · Andreas Leithner · Gonzague de Pinieux · Philippe Terrier · Valérie Laurence · Jean Michon · Ruth Ladenstein · Wolfgang Holter · Reinhard Windhager · Uta Dirksen · Peter F. Ambros · Olivier Delattre · Heinrich Kovar · Christoph Bock · Eleni M. Tomazou · Eleni M. Tomazou
Opioids: keeping the good, eliminating the bad Xueqiang Zhao · Yahui Guo · Changying Jiang · Qing Chang · Shilei Zhang · Tianming Luo · Bin Zhang · Xin Ming Jia · Mien-Chie Hung · Chen Dong · Xin Lin · Xin Lin
Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states Stephanie Puig · Howard B. Gutstein · Howard B. Gutstein
Loss of [mu] opioid receptor signaling in nociceptors, but not microglia, abrogates morphine tolerance without disrupting analgesia David Furman · Junlei Chang · Lydia Lartigue · Christopher R. Bolen · Francois Haddad · Brice Gaudilliere · Edward A. Ganio · Gabriela K. Fragiadakis · Matthew H. Spitzer · Isabelle Douchet · Sophie Daburon · Jean-François Moreau · Garry P. Nolan · Patrick Blanco · Julie Déchanet-Merville · Cornelia L. Dekker · Vladimir Jojic · Calvin J. Kuo · Mark M. Davis · Benjamin Faustin · Benjamin Faustin
Starving leukemia to induce differentiation Xiaohui Zhao · Linda Kotilinek · Benjamin Smith · Chris Hlynialuk · Kathleen R. Zahs · Martin Ramsden · J. Cleary · Karen H. Ashe · Karen H. Ashe
Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies Arnab Ghosh · Melody Smith · Scott James · Marco L. Davila · Enrico Velardi · Kimon V. Argyropoulos · Gertrude Gunset · Fabiana Perna · Fabiana M Kreines · Emily R Levy · Sophie Lieberman · Hillary Jay · Andrea Z. Tuckett · Johannes L. Zakrzewski · Lisa Tan · Lauren F. Young · Kate Takvorian · Jarrod A. Dudakov · Robert R. Jenq · Alan M. Hanash · Ana Carolina Fragoso Motta · George F. Murphy · Chen Liu · Andrea Schietinger · Michel Sadelain · Marcel R.M. van den Brink · Marcel R.M. van den Brink
T memory stem cells in health and disease Chia-Wei Cheng · Ömer H. Yilmaz · Ömer H. Yilmaz
Disease in three dimensions: Tissue engineering takes on infectious disease Luca Gattinoni · Daniel E. Speiser · Mathias Lichterfeld · Chiara Bonini · Chiara Bonini
Imaging biomarkers and biotypes for depression Shraddha Chakradhar · Shraddha Chakradhar
A microbial protein that alleviates metabolic syndrome Tor D. Wager · Choong-Wan Woo · Choong-Wan Woo
A bone marrow factor contributes to kidney disease Fernando F. Anhê · André Marette · André Marette
Nitric oxide mediates aortic disease in mice deficient in the metalloprotease Adamts1 and in a mouse model of Marfan syndrome Stuart J. Shankland · J. Ashley Jefferson · J. Ashley Jefferson
Donor CD19 CAR T cells exert potent graft-versus-lymphoma activity with diminished graft-versus-host activity Jorge Oller · Nerea Méndez-Barbero · E Josue Ruiz · Silvia Villahoz · Marjolijn Renard · Lizet I Canelas · Ana M. Briones · Rut Alberca · Noelia Lozano-Vidal · María A. Hurlé · Dianna M. Milewicz · Arturo Evangelista · Mercedes Salaices · J. Francisco Nistal · Luis Jesús Jiménez-Borreguero · Julie De Backer · Miguel R. Campanero · Juan Miguel Redondo · Juan Miguel Redondo
cGAS drives noncanonical-inflammasome activation in age-related macular degeneration Kenji Ikeda · Qianqian Kang · Takeshi Yoneshiro · Joao Paulo Camporez · Hiroko Maki · Mayu Homma · Kosaku Shinoda · Yong Chen · Xiaodan Lu · Pema Maretich · Kazuki Tajima · Kolapo M. Ajuwon · Tomoyoshi Soga · Shingo Kajimura · Shingo Kajimura
Asprosin is a centrally acting orexigenic hormone Edward L. LaGory · Amato J. Giaccia · Amato J. Giaccia
CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy Lingjuan He · Yan Li · Yi Li · Wenjuan Pu · Xiuzhen Huang · Xueying Tian · Yue Wang · Hui Zhang · Qiaozhen Liu · Libo Zhang · Huan Zhao · Juan Tang · Hongbin Ji · Dongqing Cai · Zhibo Han · Zhongchao Han · Yu Nie · Shengshou Hu · Qing-Dong Wang · Ruilin Sun · Jian Fei · Fengchao Wang · Ting Chen · Yan Yan · Hefeng Huang · William T. Pu · Bin Zhou · Bin Zhou
Prostate cancer–associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4 Cassandra Willyard · Cassandra Willyard
GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates Hana Janouskova · Geniver El Tekle · Geniver El Tekle · Elisa Bellini · Namrata D. Udeshi · Anna Rinaldi · Anna Ulbricht · Tiziano Bernasocchi · Tiziano Bernasocchi · Gianluca Civenni · Marco Losa · Tanya Svinkina · Craig M. Bielski · Craig M. Bielski · Gregory V. Kryukov · Luciano Cascione · Sara Napoli · Radoslav I. Enchev · David G. Mutch · Michael E. Carney · Andrew Berchuck · Boris Winterhoff · Russell Broaddus · Peter Schraml · Holger Moch · Francesco Bertoni · Carlo V. Catapano · Carlo V. Catapano · Matthias Peter · Steven A. Carr · Levi A. Garraway · Levi A. Garraway · Peter Wild · Jean Philippe Theurillat · Jean Philippe Theurillat · Jean Philippe Theurillat
A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels Shannon E. Mullican · Xiefan Lin-Schmidt · Chen-Ni Chin · Jose A. Chavez · Jennifer L. Furman · Anthony A Armstrong · Stephen C Beck · Victoria J South · Thai Q Dinh · Tanesha D Cash-Mason · Cassandre R Cavanaugh · Serena Nelson · Chichi Huang · Michael J. Hunter · Shamina M. Rangwala · Shamina M. Rangwala
Dickkopf‐1は直接的に,またニッチを介した機構により造血系の再生を促進する Sumeet A. Khetarpal · Xuemei Zeng · John S. Millar · Cecilia Vitali · Amritha Varshini Hanasoge Somasundara · Paolo Zanoni · James A. Landro · Nicole Barucci · William J. Zavadoski · Zhiyuan Sun · Hans de Haard · Ildiko Toth · Gina M. Peloso · Pradeep Natarajan · Marina Cuchel · Sissel Lund-Katz · Michael C. Phillips · Alan R. Tall · Sekar Kathiresan · Paul DaSilva-Jardine · Nathan A. Yates · Daniel J. Rader · Daniel J. Rader
Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT-mTORC1 activation Himburg Heather A · Quarmyne Mamle · Yan Xiao · Sasine Joshua · Zhao Liman · Kan Jenny · Pohl Katherine A · Tran Evelyn · Chute John P · Doan Phuong L · Chao Nelson J · Harris Jeffrey R · Hancock Grace · Hancock Grace
変形性関節症:老化細胞の局所での除去は外傷後変形性関節症の発症を減らし,再生促進環境を作り出す Benoit Labonté · Olivia Engmann · Immanuel Purushothaman · Caroline Ménard · Junshi Wang · Chunfeng Tan · Joseph R. Scarpa · Gregory Moy · Yong-Hwee Eddie Loh · Michael E. Cahill · Zachary S. Lorsch · Peter J. Hamilton · Erin S. Calipari · Georgia E. Hodes · Orna Issler · Hope Kronman · Madeline L. Pfau · Aleksandar Obradovic · Yan Dong · Rachael L. Neve · Scott J. Russo · Andrew Kazarskis · Carol A. Tamminga · Naguib Mechawar · Gustavo Turecki · Bin Zhang · Li Shen · Eric J. Nestler · Eric J. Nestler
GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand Jeon Ok Hee · Kim Chaekyu · Rathod Sona · Chung Jae Wook · Kim Do Hun · Elisseeff Jennifer H · Laberge Remi-Martin · Demaria Marco · Campisi Judith · Vasserot Alain P · Poon Yan · David Nathaniel · Baker Darren J · Van Deursen Jan M · Van Deursen Jan M
RNF43変異型膵腫瘍のWnt‐FZD5シグナル伝達回路がドラッガブルな脆弱性であることが,ゲノム全体にわたるCRISPRスクリーニングによって示された Linda Yang · Chihchuan Chang · Zhe Sun · Dennis Madsen · Haisun Zhu · Søren Berg Padkjær · Xiaoai Wu · Tao Huang · Karin Hultman · Sarah Juel Paulsen · Jishu Wang · Anne Bugge · Jane Boesen Frantzen · Per Nørgaard · Jacob Jeppesen · Zhiru Yang · Anna Secher · Haibin Chen · Xun Li · Linu Mary John · Bing Shan · Zhenhua He · Xiang Gao · Jing Su · Kristian T Hansen · Wei Yang · Sebastian B. Jørgensen · Sebastian B. Jørgensen
脂質代謝:代替的に活性化されたマクロファージはカテコールアミンを合成せず,脂肪組織の適応熱産生に寄与していない Steinhart Zachary · Robitaille Melanie · Angers Stephane · Pavlovic Zvezdan · Chandrashekhar Megha · Hart Traver · Wang Xiaowei · Zhang Xiaoyu · Brown Kevin R · Adams Jarrett · Pan James · Sidhu Sachdev · Moffat Jason · Jaksani Sridevi · Overmeer Rene · Boj Sylvia F · Clevers Hans · Clevers Hans
Reply to The small molecule CLP257 does not modify activity of the K + –Cl − co-transporter KCC2 but does potentiate GABA A receptor activity Lorenz H. Lehmann · Zegeye Jebessa · Michael M. Kreusser · Axel Horsch · Tao He · Mariya Kronlage · Matthias Dewenter · Viviana Sramek · Ulrike Oehl · Jutta Krebs‐Haupenthal · Albert von der Lieth · Andrea Schmidt · Qiang Sun · Julia Ritterhoff · Daniel Finke · Mirko Völkers · Andreas Jungmann · Sven W. Sauer · Christian Thiel · Alexander Nickel · Alexander Nickel · Michael Kohlhaas · Michael Kohlhaas · Michaela Schäfer · Carsten Sticht · Christoph Maack · Christoph Maack · Norbert Gretz · Michael Wagner · Ali El-Armouche · Lars S. Maier · Juan E. Camacho Londoño · Benjamin Meder · Marc Freichel · Hermann Josef Gröne · Patrick Most · Oliver Müller · Stephan Herzig · Eileen E. M. Furlong · Hugo A. Katus · Johannes Backs · Johannes Backs
老化:長期的な低用量Δ9‐テトラヒドロカンナビノール(THC)投与は老齢マウスの認知機能を回復させる He Jing · Zhang Xia · Sun Xiaolin · Jin Yuebo · Gan Yuzhou · Jia Rulin · Xu Chuanhui · Zhu Lei · An Yuan · Jia Yuan · Li Chun · Liu Xu · Ye Hua · Ren Limin · Li Ru · Yao Haihong · Li Yuhui · Chen Shi · Zhang Xuewu · Su Yin · Guo Jianping · Li Zhanguo · Wei Yunbo · Hou Zhaohua · Feng Jinhong · Yu Di · Chen Yaping · Hu Xin · Leong Yew Ann · Deng Jun · Shen Nan · Morand Eric F · Morand Eric F
喘息:NETosisによって放出された宿主DNAは,ライノウイルスが誘導する2型免疫によるアレルギー性喘息増悪を促進する Bilkei‐Gorzo Andras · Albayram Onder · Michel Kerstin · Piyanova Anastasia · Racz Ildiko · Imbeault Sophie · Zimmer Andreas · Draffehn Astrid · Ulas Thomas · Schultze Joachim L · Oppenheimer Hannah · Dvir‐Ginzberg Mona · Bab Itai · Bab Itai
Breaking through: How researchers are gaining entry into barricaded bacteria Toussaint Marie · Jackson David J · Swieboda Dawid · Guedan Anabel · Ching Yee Man · Makrinioti Heidi · Aniscenko Julia · Edwards Michael R · Solari Roberto · Johnston Sebastian L · Tsourouktsoglou Theodora‐Dorita · Papayannopoulos Venizelos · Radermecker Coraline · Bureau Fabrice · Marichal Thomas · Farnir Frederic · Farnir Frederic
A proteolytic fragment of histone deacetylase 4 protects the heart from failure by regulating the hexosamine biosynthetic pathway Daniel Gamu · A. Russell Tupling · A. Russell Tupling
白血病:単一細胞トランスクリプトミクスによって明らかになった,慢性骨髄性白血病の幹細胞で見られる異なる分子シグネチャー Adriaens Carmen · Standaert Laura · Barra Jasmine · Leucci Eleonora · Marine Jean-Christophe · Latil Mathilde · Lapouge Gaeelle · Beck Benjamin · Blanpain Cedric · Verfaillie Annelien · Aerts Stein · Kalev Peter · Sablina Anna A · Boeckx Bram · Lambrechts Diether · Wijnhoven Paul W G · Radaelli Enrico · Vermi William · van den Oord Joost · Nakagawa Shinichi · Hirose Tetsuro · Hirose Tetsuro
The epigenome editors: How tools such as CRISPR offer new details about epigenetics Giustacchini Alice · Thongjuea Supat · Barkas Nikolaos · Povinelli Benjamin J · Booth Christopher A G · Sopp Paul · Norfo Ruggiero · Rodriguez‐Meira Alba · Ashley Neil · Jamieson Lauren · Vyas Paresh · Jacobsen Sten Eirik W · Mead Adam J · Woll Petter S · Anderson Kristina · Segerstolpe Asa · Sandberg Rickard · Qian Hong · Olsson‐Stroemberg Ulla · Mustjoki Satu · Mustjoki Satu
抗体10‐1074はHIV‐1感染者でウイルス血症を抑制する Cassandra Willyard · Cassandra Willyard
炎症性腸疾患:オンコスタチンMは腸の炎症を引き起こし,炎症性腸疾患の患者での腫瘍壊死因子中和療法への応答性を予測する Caskey Marina · Schoofs Till · Settler Allison · Karagounis Theodora · Nogueira Lilian · Oliveira Thiago Y · Cohen Yehuda Z · Shimeliovich Irina · Unson‐O’Brien Cecilia · Levin Rebeka · Witmer‐Pack Maggi · Schlesinger Sarah J · Nussenzweig Michel C · Gruell Henning · Weiland Daniela · Klein Florian · Lehmann Clara · Gillor Daniel · Kuemmerle Tim · Wyen Christoph · Faetkenheuer Gerd · Kreider Edward F · Learn Gerald H · Hahn Beatrice H · Murrell Ben · Ignacio Caroline · Pfeifer Nico · Robles Alexander · Seaman Michael S. · Eren Kemal · Kiss Szilard · West Anthony P · Bjorkman Pamela J · Mouquet Hugo · Zingman Barry S · Gulick Roy M · Keler Tibor · Keler Tibor
Opposing effects of cancer-type-specific SPOP mutants on BET protein degradation and sensitivity to BET inhibitors Xiangpeng Dai · Wenjian Gan · Xiaoning Li · Xiaoning Li · Shangqian Wang · Wei Zhang · Ling Huang · Shengwu Liu · Qing Zhong · Jianping Guo · Jinfang Zhang · Ting Chen · Kouhei Shimizu · Francisco Beca · Mirjam Blattner · Divya Vasudevan · Dennis L. Buckley · Jun Qi · Lorenz Buser · Pengda Liu · Pengda Liu · Hiroyuki Inuzuka · Andrew H. Beck · Liewei Wang · Peter Wild · Levi A. Garraway · Mark A. Rubin · Christopher E. Barbieri · Kwok-Kin Wong · Senthil K. Muthuswamy · Jiaoti Huang · Yu Chen · James E. Bradner · Wenyi Wei · Wenyi Wei
Sex-specific transcriptional signatures in human depression Pingzhao Zhang · Dejie Wang · Dejie Wang · Yu Zhao · Shancheng Ren · Kun Gao · Zhenqing Ye · Shangqian Wang · Chun Wu Pan · Yasheng Zhu · Yuqian Yan · Yinhui Yang · Di Wu · Yundong He · Jun Zhang · Daru Lu · Xiuping Liu · Long Yu · Shimin Zhao · Yao Li · Dong Lin · Yuzhuo Wang · Liguo Wang · Yu Chen · Yinghao Sun · Chenji Wang · Haojie Huang · Haojie Huang
Recognition of self-DNA drives cardiac inflammation: why broken hearts fail Martin Gagnon · Marc J. Bergeron · Jimena Perez-Sanchez · Isabel Plasencia-Fernández · Louis-Etienne Lorenzo · Antoine G. Godin · Annie Castonguay · Robert P. Bonin · Yves De Koninck · Yves De Koninck
Human primary liver cancer–derived organoid cultures for disease modeling and drug screening Teresa Palomero · Adolfo A. Ferrando · Adolfo A. Ferrando
A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice Monica Vaccari · Shari N. Gordon · Slim Fourati · Luca Schifanella · Namal P.M. Liyanage · Mark J. Cameron · Brandon F. Keele · Xiaoying Shen · Georgia D. Tomaras · Erik Billings · Mangala Rao · Amy W. Chung · Karen G. Dowell · Chris Bailey-Kellogg · Eric P. Brown · Margaret E. Ackerman · Diego A. Vargas-Inchaustegui · Stephen Whitney · Melvin N. Doster · Nicolo Binello · Poonam Pegu · David C. Montefiori · Kathryn E. Foulds · David S. Quinn · Mitzi Donaldson · Frank Liang · Karin Loré · Mario Roederer · Richard A. Koup · Adrian B. McDermott · Zhong-Min Ma · Christopher J. Miller · Tran B. Phan · Donald N. Forthal · Matthew Blackburn · Francesca Caccuri · Massimiliano Bissa · Guido Ferrari · V. S. Kalyanaraman · Maria Grazia Ferrari · DeVon Thompson · Marjorie Robert-Guroff · Silvia Ratto-Kim · Jerome H. Kim · Nelson L. Michael · Sanjay Phogat · Susan W. Barnett · Jim Tartaglia · David Venzon · Donald Stablein · Galit Alter · Rafick-Pierre Sekaly · Genoveffa Franchini · Genoveffa Franchini
Thalamic miR-338-3p mediates auditory thalamocortical disruption and its late onset in models of 22q11.2 microdeletion Hubert Plovier · Amandine Everard · Céline Druart · Clara Depommier · Matthias Van Hul · Lucie Geurts · Julien Chilloux · Noora Ottman · Thibaut Duparc · Laeticia Lichtenstein · Antonis Myridakis · Nathalie M. Delzenne · Judith Klievink · Arnab Bhattacharjee · Kees C. H. van der Ark · Steven Aalvink · Laurent O. Martinez · Marc-Emmanuel Dumas · Dominique Maiter · Audrey Loumaye · Michel Hermans · Jean-Paul Thissen · Clara Belzer · Willem M. de Vos · Patrice D. Cani · Patrice D. Cani
Enhancing the precision of genetic lineage tracing using dual recombinases Misu Hirofumi · Takayama Hiroaki · Kikuchi Akihiro · Ishii Kiyo‐aki · Takamura Toshinari · Chikamoto Keita · Kanamori Takehiro · Tajima Natsumi · Lan Fei · Takeshita Yumie · Honda Masao · Kaneko Shuichi · Saito Yoshiro · Mita Yuichiro · Yoshioka Yuya · Noguchi Noriko · Matsugo Seiichi · Tanaka Mutsumi · Kato Seiji · Matsuyama Naoto · Iwayama Kaito · Tokuyama Kumpei · Akazawa Nobuhiko · Maeda Seiji · Takekoshi Kazuhiro · Takekoshi Kazuhiro
運動効果:ヘパトカインであるセレノプロテインPの欠損は,筋での活性酸素種およびAMPKの上方制御によりマウスの運動応答性を増強する Amanda B. Keener · Amanda B. Keener
An ALOX12–12-HETE–GPR31 signaling axis is a key mediator of hepatic ischemia–reperfusion injury Kory J. Lavine · Douglas L. Mann · Douglas L. Mann
Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth Louise Carter · Dominic G. Rothwell · Barbara Mesquita · Christopher Smowton · Hui Sun Leong · Fabiola Fernandez-Gutierrez · Yaoyong Li · Deborah J. Burt · Jenny Antonello · Christopher J. Morrow · Cassandra L Hodgkinson · Karen Morris · Lynsey Priest · Mathew Carter · Crispin J. Miller · Andrew Hughes · Fiona Blackhall · Caroline Dive · Ged Brady · Ged Brady
Uncovering cancer: How enlisting T cells can boost the power of immunotherapy Emily Bowers · Anastasiya Slaughter · Paul S. Frenette · Rork Kuick · Oscar M. Pello · Daniel Lucas · Daniel Lucas
Granulocyte-derived TNFα promotes vascular and hematopoietic regeneration in the bone marrow Laura Jeanne Broutier · Gianmarco Mastrogiovanni · Monique M.A. Verstegen · Hayley E. Francies · Lena Morrill Gavarró · Charles R. Bradshaw · George E. Allen · Robert Arnes-Benito · Olga Sidorova · M. Gaspersz · Nikitas Georgakopoulos · Bon-Kyoung Koo · Sabine Dietmann · Susan E. Davies · Raaj K. Praseedom · Ruby Lieshout · Jan N. M. IJzermans · Stephen J. Wigmore · Kourosh Saeb-Parsy · Mathew J. Garnett · Luc J. W. van der Laan · Meritxell Huch · Meritxell Huch
Molecular analysis of circulating tumor cells identifies distinct copy-number profiles in patients with chemosensitive and chemorefractory small-cell lung cancer Amanda B. Keener · Amanda B. Keener

Searching for Alzheimers disease therapies
Nature Medicine | 2018
Darren C. Johnson · Cornelius Y. Taabazuing · Marian C. Okondo · Ashley J. Chui · Sahana D. Rao · Fiona Brown · Casie Reed · Elizabeth Peguero · Elisa de Stanchina · Alex Kentsis · Daniel A. Bachovchin · Daniel A. Bachovchin · Daniel A. Bachovchin
Publisher Correction: Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis
Nature Medicine | 2018
Neibla Priego · Lucía Zhu · Cátia Monteiro · Manon Mulders · David Wasilewski · Wendy Bindeman · Laura Doglio · Liliana Martínez · Elena Martinez-Saez · Santiago Ramón y Cajal · Diego Megías · Elena Hernández-Encinas · Carmen Blanco-Aparicio · Lola Martínez · Eduardo Zarzuela · Javier Muñoz · Coral Fustero-Torre · Elena Piñeiro-Yáñez · Aurelio Hernández-Laín · Luca Bertero · Valeria Poli · Melchor Sanchez-Martinez · Javier A. Menendez · Riccardo Soffietti · Joaquim Bosch-Barrera · Manuel Valiente · Manuel Valiente
Author Correction: STAT3 labels a subpopulation of reactive astrocytes required for brain metastasis
Nature Medicine | 2018
Yong Jie Zhang · Tania F. Gendron · Mark T. W. Ebbert · Aliesha D. O’Raw · Mei Yue · Karen Jansen-West · Xu Zhang · Mercedes Prudencio · Jeannie Chew · Casey Cook · Lillian M. Daughrity · Jimei Tong · Yuping Song · Sarah R. Pickles · Monica Castanedes-Casey · Aishe Kurti · Rosa Rademakers · Bjorn Oskarsson · Dennis W. Dickson · Wenqian Hu · Aaron D. Gitler · John D. Fryer · Leonard Petrucelli · Leonard Petrucelli
Poly(GR) impairs protein translation and stress granule dynamics in C9orf72 -associated frontotemporal dementia and amyotrophic lateral sclerosis
Nature Medicine | 2018
Sunad Rangarajan · Nathaniel B. Bone · Anna A. Zmijewska · Shaoning Jiang · Dae Won Park · Dae Won Park · Karen Bernard · Morgan L. Locy · Saranya Ravi · Jessy Deshane · Roslyn B. Mannon · Edward Abraham · Victor M. Darley-Usmar · Victor J. Thannickal · Jaroslaw W. Zmijewski · Jaroslaw W. Zmijewski