Journal Impact IF - Analysis · Trend · Prediction · Ranking


Journal Impact IF




Journal Impact IF Trend

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The 2019-2020 Journal Impact IF of Diabetologia is 7.518, which is just updated in 2020.

Diabetologia Impact Factor
Highest IF
Highest Journal Impact IF

The highest Journal Impact IF of Diabetologia is 7.518.

Lowest IF
Lowest Journal Impact IF

The lowest Journal Impact IF of Diabetologia is 6.023.

Total Growth Rate
IF Total Growth Rate

The total growth rate of Diabetologia IF is 10.3%.

Annual Growth Rate
IF Annual Growth Rate

The annual growth rate of Diabetologia IF is 1.1%.

Journal Impact IF Ranking

Subcategory Quartile Rank Percentile
Internal Medicine Q1 5/128

Internal Medicine 96%

Endocrinology, Diabetes and Metabolism Q1 9/217

Endocrinology, Diabetes and Metabolism 96%

Journal Impact IF Ranking

· In the Internal Medicine research field, the Quartile of Diabetologia is Q1. Diabetologia has been ranked #5 over 128 related journals in the Internal Medicine research category. The ranking percentile of Diabetologia is around 96% in the field of Internal Medicine.
· In the Endocrinology, Diabetes and Metabolism research field, the Quartile of Diabetologia is Q1. Diabetologia has been ranked #9 over 217 related journals in the Endocrinology, Diabetes and Metabolism research category. The ranking percentile of Diabetologia is around 96% in the field of Endocrinology, Diabetes and Metabolism.

Diabetologia Impact Factor 2020-2021 Prediction

Diabetologia Impact Factor Predition System

Diabetologia Impact Factor Prediction System is now online. You can start share your valuable insights with the community.

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Total Publications
Total Citations

Annual Publication Volume

Annual Citation Record

International Collaboration Trend

Cited Documents Trend

Journal Impact IF History

Year Journal Impact IF
Year Journal Impact IF
2019-2020 7.518
2018-2019 7.113
2017-2018 6.023
2016-2017 6.08
2015-2016 6.206
2014-2015 6.671
2013-2014 6.88
2012-2013 6.487
2011-2012 6.814
Journal Impact IF History

· The 2019-2020 Journal Impact IF of Diabetologia is 7.518
· The 2018-2019 Journal Impact IF of Diabetologia is 7.113
· The 2017-2018 Journal Impact IF of Diabetologia is 6.023
· The 2016-2017 Journal Impact IF of Diabetologia is 6.08
· The 2015-2016 Journal Impact IF of Diabetologia is 6.206
· The 2014-2015 Journal Impact IF of Diabetologia is 6.671
· The 2013-2014 Journal Impact IF of Diabetologia is 6.88
· The 2012-2013 Journal Impact IF of Diabetologia is 6.487
· The 2011-2012 Journal Impact IF of Diabetologia is 6.814

Publications Cites Dataset

Year Publications Citations
Year Publications Citations
1965 21 7
1966 80 80
1967 105 242
1968 94 442
1969 114 386
1970 120 721
1971 95 767
1972 71 723
1973 90 819
1974 117 972
1975 97 1403
1976 100 1401
1977 110 1705
1978 140 1959
1979 126 2349
1980 206 2664
1981 238 3674
1982 236 3812
1983 218 4750
1984 242 4771
1985 172 5151
1986 178 5383
1987 199 5748
1988 186 6919
1989 173 7210
1990 152 6857
1991 217 7094
1992 233 8619
1993 268 8508
1994 273 8822
1995 289 9673
1996 316 10456
1997 382 10761
1998 298 12093
1999 312 14535
2000 291 16504
2001 343 18426
2002 333 20190
2003 300 23588
2004 380 24717
2005 466 27472
2006 515 30742
2007 451 34501
2008 454 38666
2009 504 39102
2010 542 42640
2011 490 45437
2012 450 50411
2013 420 53084
2014 394 53809
2015 438 51211
2016 419 47134
2017 402 44340
2018 340 38640
2019 293 42166
2020 278 50751
2021 57 3287
Publications Cites Dataset

· The Diabetologia has published 21 reports and received 7 citations in 1965.
· The Diabetologia has published 80 reports and received 80 citations in 1966.
· The Diabetologia has published 105 reports and received 242 citations in 1967.
· The Diabetologia has published 94 reports and received 442 citations in 1968.
· The Diabetologia has published 114 reports and received 386 citations in 1969.
· The Diabetologia has published 120 reports and received 721 citations in 1970.
· The Diabetologia has published 95 reports and received 767 citations in 1971.
· The Diabetologia has published 71 reports and received 723 citations in 1972.
· The Diabetologia has published 90 reports and received 819 citations in 1973.
· The Diabetologia has published 117 reports and received 972 citations in 1974.
· The Diabetologia has published 97 reports and received 1403 citations in 1975.
· The Diabetologia has published 100 reports and received 1401 citations in 1976.
· The Diabetologia has published 110 reports and received 1705 citations in 1977.
· The Diabetologia has published 140 reports and received 1959 citations in 1978.
· The Diabetologia has published 126 reports and received 2349 citations in 1979.
· The Diabetologia has published 206 reports and received 2664 citations in 1980.
· The Diabetologia has published 238 reports and received 3674 citations in 1981.
· The Diabetologia has published 236 reports and received 3812 citations in 1982.
· The Diabetologia has published 218 reports and received 4750 citations in 1983.
· The Diabetologia has published 242 reports and received 4771 citations in 1984.
· The Diabetologia has published 172 reports and received 5151 citations in 1985.
· The Diabetologia has published 178 reports and received 5383 citations in 1986.
· The Diabetologia has published 199 reports and received 5748 citations in 1987.
· The Diabetologia has published 186 reports and received 6919 citations in 1988.
· The Diabetologia has published 173 reports and received 7210 citations in 1989.
· The Diabetologia has published 152 reports and received 6857 citations in 1990.
· The Diabetologia has published 217 reports and received 7094 citations in 1991.
· The Diabetologia has published 233 reports and received 8619 citations in 1992.
· The Diabetologia has published 268 reports and received 8508 citations in 1993.
· The Diabetologia has published 273 reports and received 8822 citations in 1994.
· The Diabetologia has published 289 reports and received 9673 citations in 1995.
· The Diabetologia has published 316 reports and received 10456 citations in 1996.
· The Diabetologia has published 382 reports and received 10761 citations in 1997.
· The Diabetologia has published 298 reports and received 12093 citations in 1998.
· The Diabetologia has published 312 reports and received 14535 citations in 1999.
· The Diabetologia has published 291 reports and received 16504 citations in 2000.
· The Diabetologia has published 343 reports and received 18426 citations in 2001.
· The Diabetologia has published 333 reports and received 20190 citations in 2002.
· The Diabetologia has published 300 reports and received 23588 citations in 2003.
· The Diabetologia has published 380 reports and received 24717 citations in 2004.
· The Diabetologia has published 466 reports and received 27472 citations in 2005.
· The Diabetologia has published 515 reports and received 30742 citations in 2006.
· The Diabetologia has published 451 reports and received 34501 citations in 2007.
· The Diabetologia has published 454 reports and received 38666 citations in 2008.
· The Diabetologia has published 504 reports and received 39102 citations in 2009.
· The Diabetologia has published 542 reports and received 42640 citations in 2010.
· The Diabetologia has published 490 reports and received 45437 citations in 2011.
· The Diabetologia has published 450 reports and received 50411 citations in 2012.
· The Diabetologia has published 420 reports and received 53084 citations in 2013.
· The Diabetologia has published 394 reports and received 53809 citations in 2014.
· The Diabetologia has published 438 reports and received 51211 citations in 2015.
· The Diabetologia has published 419 reports and received 47134 citations in 2016.
· The Diabetologia has published 402 reports and received 44340 citations in 2017.
· The Diabetologia has published 340 reports and received 38640 citations in 2018.
· The Diabetologia has published 293 reports and received 42166 citations in 2019.
· The Diabetologia has published 278 reports and received 50751 citations in 2020.
· The Diabetologia has published 57 reports and received 3287 citations in 2021.
· The total publications of Diabetologia is 14828.
· The total citations of Diabetologia is 958294.

What is Impact Factor?

The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly average number of citations of articles published in the last two years in a given journal. It is frequently used as a proxy for the relative importance of a journal within its field; journals with higher impact factor values are often deemed to be more important, or carry more intrinsic prestige in their respective fields, than those with lower values.

Diabetologia | Academic Accelerator - About the Impact Factor

Impact factor is commonly used to evaluate the relative importance of a journal within its field and to measure the frequency with which the “average article” in a journal has been cited in a particular time period. Journal which publishes more review articles will get highest IFs. Journals with higher IFs believed to be more important than those with lower ones. According to Eugene Garfield “impact simply reflects the ability of the journals and editors to attract the best paper available.” Journal which publishes more review articles will get maximum IFs. The Impact Factor of an academic journal is a scientometric Metric that reflects the yearly average number of citations that recent articles published in a given journal received. It is frequently used as a Metric for the relative importance of a journal within its field; journals with higher Impact Factor are often deemed to be more important than those with lower ones. The Diabetologia Impact Factor IF measures the average number of citations received in a particular year (2020) by papers published in the Diabetologia during the two preceding years (2018-2019). Note that 2020 Impact Factor are reported in 2021; they cannot be calculated until all of the 2020 publications have been processed by the indexing agency. New journals, which are indexed from their first published issue, will receive an impact factor after two years of indexing; in this case, the citations to the year prior to Volume 1, and the number of articles published in the year prior to Volume 1, are known zero values. Journals that are indexed starting with a volume other than the first volume will not get an impact factor until they have been indexed for three years. Occasionally, Journal Citation Reports assigns an impact factor to new journals with less than two years of indexing, based on partial citation data. The calculation always uses two complete and known years of item counts, but for new titles one of the known counts is zero. Annuals and other irregular publications sometimes publish no items in a particular year, affecting the count. The impact factor relates to a specific time period; it is possible to calculate it for any desired period. In addition to the 2-year Impact Factor, the 3-year Impact Factor, 4-year Impact Factor, 5-year Impact Factor, Real-Time Impact Factor can provide further insights and factors into the impact of Diabetologia.


The impact factor was devised by Eugene Garfield, the founder of the Institute for Scientific Information (ISI). Impact factors are calculated yearly starting from 1975 for journals listed in the Journal Citation Reports (JCR). ISI was acquired by Thomson Scientific & Healthcare in 1992, and became known as Thomson ISI. In 2018, Thomson ISI was sold to Onex Corporation and Baring Private Equity Asia. They founded a new corporation, Clarivate, which is now the publisher of the JCR.


The impact factor is used to compare different journals within a certain field. The Web of Science indexes more than 11,500 science and social science journals. Journal impact factors are often used to evaluate the merit of individual articles and individual researchers. This use of impact factors was summarised by Hoeffel:

Impact Factor is not a perfect tool to measure the quality of articles but there is nothing better and it has the advantage of already being in existence and is, therefore, a good technique for scientific evaluation. Experience has shown that in each specialty the best journals are those in which it is most difficult to have an article accepted, and these are the journals that have a high impact factor. Most of these journals existed long before the impact factor was devised. The use of impact factor as a measure of quality is widespread because it fits well with the opinion we have in each field of the best journals in our specialty....In conclusion, prestigious journals publish papers of high level. Therefore, their impact factor is high, and not the contrary.

Eugene Garfield

In brief, Impact factors may be used by:
  • Authors to decide where to submit an article for publication.
  • Libraries to make collection development decisions
  • Academic departments to assess academic productivity
  • Academic departments to make decisions on promotion and tenure.
As impact factors are a journal-level metric, rather than an article- or individual-level metric, this use is controversial. Garfield agrees with Hoeffel,but warns about the "misuse in evaluating individuals" because there is "a wide variation [of citations] from article to article within a single journal". Other things to consider about Impact Factors:
  • Many journals do not have an impact factor.
  • The impact factor cannot assess the quality of individual articles. Even if citations were evenly distributed among articles, the impact factor would only measure the interests of other researchers in an article, not its importance and usefulness.
  • Only research articles, technical notes and reviews are “citable” items. Editorials, letters, news items and meeting abstracts are “non-citable items”.
  • Only a small percentage of articles are highly cited and they are found in a small subset of journals. This small proportion accounts for a large percentage of citations.
  • Controversial papers, such as those based on fraudulent data, may be highly cited, distorting the impact factor of a journal.
  • Citation bias may exist. For example, English language resources may be favoured. Authors may cite their own work.
Moreover, informed and careful use of these impact data is essential, and should be based on a thorough understanding of the methodology used to generate impact factors. There are controversial aspects of using impact factors:
  • It is not clear whether the number of times a paper is cited measures its actual quality.
  • Some databases that calculate impact factors fail to incorporate publications including textbooks, handbooks and reference books.
  • Certain disciplines have low numbers of journals and usage. Therefore, one should only compare journals or researchers within the same discipline.
  • Review articles normally are cited more often and therefore can skew results.
  • Self-citing may also skew results.
  • Some resources used to calculate impact factors have inadequate international coverage.
  • Editorial policies can artificially inflate an impact factor.
Impact factors have often been used in advancement and tenure decision-making. Many recognize that this is a coarse tool for such important decisions, and that a multitude of factors should be taken into account in these deliberations. When considering the use of the impact factor (IF), keep these aspects in mind:
  • IF analysis is limited to citations from the journals indexed by the Web of Science/Web of Knowledge. Currently, the Web of Science indexes only 8621 journals across the full breadth of the sciences, and just 3121 in the social sciences.
  • A high IF/citation rate says nothing about the quality -- or even, validity -- of the references being cited. Notorious or even retracted articles often attract a lot of attention, hence a high number of citations. The notority related to the first publication on "cold fusion" is one such example.
  • Journals that publish more "review articles" are often found near the top of the rankings. While not known for publishing new, creative findings, these individual articles tend to be heavily cited.
  • The IF measures the average number of citations to articles in the journal -- given this, a small number of highly-cited articles will skew the figure.
  • It takes several years for new journals to be added to the list of titles indexed by the Web of Science/Web of Knowledge, so these newer titles will be under-represented.
  • It's alleged that journal editors have learned to "game" the system, encouraging authors to cite their works previously published in the same journal.
Comparing Journals Across Disciplines? Not a good idea! Using Impact Factors within a given discipline should only be done with great care, as described above. Using impact factor data to compare journals across disciplines is even more problematic. Here are some of the reasons:
  • Disciplines where older literature is still referenced, such as Chemistry and Mathematics, offer challenges to the methodolgy since older citations (older than two years) are not used to calculate the impact factor for a given journal. (Five-year impact factor analysis, which can be calculated using the Journal Citation Index database, helps smooth out this problem only to some degree.)
  • Different disciplines have different practices regarding tendency to cite larger numbers of references. Higher overall citation rates will bump upward impact factor measurements.
  • Where it's common for large numbers of authors to collaborate on a single paper, such as in Physics, the tendency of authors to cite themselves (and in this case, more authors) will result in increased citation rates.

Pros and Cons of the Impact Factor


  • A vetted, established metric for measuring journal impact within a discipline.
  • Designed to eliminate bias based on journal size and frequency.
  • Individual articles makes an uneven contribution to overall Impact Factor.
  • Impact Factor does not account for certain things, things like context (postive or negative citaion) and intentionality (self-citation).
  • The metric is proprietary to and bound by the contents of the Thomson Reuters database.
  • Citations, on which the Impact Factor is based, count for less than 1% of an article's overall use.


Numerous critiques have been made regarding the use of impact factors. A 2007 study noted that the most fundamental flaw is that impact factors present the mean of data that are not normally distributed, and suggested that it would be more appropriate to present the median of these data. There is also a more general debate on the validity of the impact factor as a measure of journal importance and the effect of policies that editors may adopt to boost their impact factor (perhaps to the detriment of readers and writers). Other criticism focuses on the effect of the impact factor on behavior of scholars, editors and other stakeholders. Others have made more general criticisms, arguing that emphasis on impact factor results from negative influence of neoliberal policies on academia claiming that what is needed is not just replacement of the impact factor with more sophisticated metrics for science publications but also discussion on the social value of research assessment and the growing precariousness of scientific careers in higher education.
Experts stress that there are limitations in using impact factors to evaluate a scholar's work. There are many reasons cited for not relying on impact factor alone to evaluate the output of a particular individual. Among these are the following:

  • A single factor is not sufficient for evaluating an author's work.
  • Journal values are meaningless unless compared within the same discipline. Impact factors vary among disciplines.
  • The impact factor was originally devised to show the impact of a specific journal, not a specific scholar. The quality and impact of the author's work may extend beyond the impact of a particular journal.
According to Jim Testa, a researcher for ThomsonReuters Scientific, the most widespread misuse of the Impact Factor is to evaluate the work of an individual author (instead of a journal). "To say that because a researcher is publishing in a certain journal, he or she is more influential or deserves more credit is not necessarily true. There are many other variables to consider." (interview 6/26/2008 in Thomson Reuters blog entry)

Journal Profile


Diabetologia publishes original clinical, translational and experimental research on all aspects of diabetes research and related subjects, provided they have scientific merit and represent an important advance in knowledge. Diabetologia is a monthly peer-reviewed medical journal covering diabetology and is the official journal of the European Association for the Study of Diabetes. It is published by Springer Science+Business Media and the editor-in-chief is Hindrik Mulder (Lund University). According to the Journal Citation Reports, the journal has a 2019 impact factor of 7.518, ranking it 10th out of 143 journals in the category Endocrinology & Metabolism.

Highly Cited Keywords


The ISSN of Diabetologia is 0012-186X . An ISSN is an 8-digit code used to identify newspapers, journals, magazines and periodicals of all kinds and on all media–print and electronic.

ISSN (Online)
ISSN (Online)

The ISSN (Online) of Diabetologia is 1432-0428 . An ISSN is an 8-digit code used to identify newspapers, journals, magazines and periodicals of all kinds and on all media–print and electronic.

Springer Verlag

Diabetologia is published by Springer Verlag .

Publication Frequency
Publication Frequency

Diabetologia publishes reports Monthly .

1965 - Present

The Publication History of Diabetologia covers 1965 - Present .

Open Access
Open Access

Diabetologia is Subscription-based (non-OA) Journal. Publishers own the rights to the articles in their journals. Anyone who wants to read the articles should pay by individual or institution to access the articles. Anyone who wants to use the articles in any way must obtain permission from the publishers.

Publication Fee
Publication Fee

There is no publication fee for submiting manuscript to Diabetologia. Diabetologia is Subscription-based (non-OA) Journal. Publishers own the rights to the articles in their journals. Anyone who wants to read the articles should pay by individual or institution to access the articles.


The language of Diabetologia is English .


The publisher of Diabetologia is Springer Verlag , which locates in Germany .

Selected Articles

Full Title Authors
Full Title Authors
Gestational weight gain: an ounce of prevention is still worth a pound of cure Rachel Dankner · Rachel Dankner · Rachel Dankner · Lital Keinan Boker · Lital Keinan Boker · Laurence S. Freedman · Laurence S. Freedman
The shape of the glucose concentration curve during an oral glucose tolerance test predicts risk for type 1 diabetes Lærke S. Gasbjerg · Mikkel Christensen · Bolette Hartmann · Amalie R. Lanng · Alexander Hovard Sparre-Ulrich · Maria Buur Nordskov Gabe · Flemming Dela · Tina Vilsbøll · Jens J. Holst · Mette M. Rosenkilde · Filip K. Knop · Filip K. Knop
Random non-fasting C-peptide testing can identify patients with insulin-treated type 2 diabetes at high risk of hypoglycaemia Adam Hulman · Adam Hulman · Dorte Vistisen · Charlotte Glümer · Michael Bergman · Daniel R. Witte · Kristine Færch · Kristine Færch
Glucose patterns during an oral glucose tolerance test and associations with future diabetes, cardiovascular disease and all-cause mortality rate Lauren M. Sparks · Lauren M. Sparks
The chromosome 6q22.33 region is associated with age at diagnosis of type 1 diabetes and disease risk in those diagnosed under 5 years of age Zuzana Lohse · Zuzana Lohse · Sine Knorr · Birgitte Bytoft · Birgitte Bytoft · Tine D. Clausen · Rikke Beck Jensen · Peter S. Oturai · Henning Beck-Nielsen · Claus Højbjerg Gravholt · Peter Damm · Peter Damm · Kurt Højlund · Kurt Højlund · Dorte Møller Jensen · Dorte Møller Jensen · Dorte Møller Jensen
Genetic variants of gestational diabetes mellitus: a study of 112 SNPs among 8722 women in two independent populations N. Seemann · A. Welling · Ingo Rustenbeck · Ingo Rustenbeck
Overweight, obesity and the risk of LADA : results from a Swedish case–control study and the Norwegian HUNT Study Anne Gemmink · S. Daemen · Bram Brouwers · Joris Hoeks · E. Kornips · Gert Schaart · Patrick Schrauwen · Matthijs K. C. Hesselink · Matthijs K. C. Hesselink
Lp-PLA2 activity is associated with increased risk of diabetic retinopathy: a longitudinal disease progression study M. A. A. Vogel · Johan W.E. Jocken · Henrike Sell · Nicole Hoebers · Yvonne Essers · K. Rouschop · Merima Čajlaković · Ellen E. Blaak · Gijs H. Goossens · Gijs H. Goossens
Can targeting ANGPTL proteins improve glucose tolerance Feng-Cheng Chou · Heng-Yi Chen · Hsin-Hui Chen · Gu-Jiun Lin · Shih-Hua Lin · Huey-Kang Sytwu · Huey-Kang Sytwu
DEVOTE 3: Temporal relationships between severe hypoglycaemia, cardiovascular outcomes and mortality Peter Achenbach · Mohammed I. Hawa · Stephanie Krause · Vito Lampasona · Samuel T. Jerram · Alistair J K Williams · Ezio Bonifacio · Anette-G. Ziegler · R. David Leslie · R. David Leslie
Autoantibodies to N-terminally truncated GAD improve clinical phenotyping of individuals with adult-onset diabetes: Action LADA 12 Roderick E. Warren · Roderick E. Warren
Metabolomics insights into early type 2 diabetes pathogenesis and detection in individuals with normal fasting glucose Elena Beltramo · A Mazzeo · Massimo Porta · Massimo Porta
Flash glucose monitoring: objective, not self-referential, outcomes are needed Y. M. H. Bruls · M. de Ligt · L. Lindeboom · Esther Phielix · Bas Havekes · J. E. Wildberger · Matthijs K. C. Hesselink · P. Schrauwen · V. B. Schrauwen · V. B. Schrauwen
Altered mitochondrial bioenergetics and ultrastructure in the skeletal muscle of young adults with type 1 diabetes Joreintje D. Mackenbach · Nicole den Braver · Joline W.J. Beulens · Joline W.J. Beulens
Persistence of abnormalities in white matter in children with type 1 diabetes A Mazzeo · Elena Beltramo · C Gai · T Lopatina · Marina Trento · Massimo Porta · Massimo Porta
Spouses, social networks and other upstream determinants of type 2 diabetes mellitus Kathrin Maedler · Payal Shah · Navina Lueschen · Amin Ardestani · Johan Olerud · P-O Carlsson · P-O Carlsson
Effects of acute NEFA manipulation on incretin-induced insulin secretion in participants with and without type 2 diabetes Francesco Zaccardi · Nafeesa N. Dhalwani · David R. Webb · Melanie J. Davies · Kamlesh Khunti · Kamlesh Khunti
Global burden of hypoglycaemia-related mortality in 109 countries, from 2000 to 2014: an analysis of death certificates Joel Dunn · Pratik Choudhary · Pratik Choudhary · M M Teh · M M Teh · Ian A. Macdonald · Katharine F. Hunt · Katharine F. Hunt · Paul Marsden · Stephanie A. Amiel · Stephanie A. Amiel · Stephanie A. Amiel
Plasma branched chain/aromatic amino acids, enriched Mediterranean diet and risk of type 2 diabetes: case-cohort study within the PREDIMED Trial Else M. Balke · Simke Demeester · DaHae Lee · DaHae Lee · Pieter Gillard · Pieter Gillard · Robert Hilbrands · Ursule Van de Velde · Bart Van der Auwera · Zhidong Ling · Bart O. Roep · Bart O. Roep · Daniel Pipeleers · Bart Keymeulen · Frans K. Gorus · Frans K. Gorus
Medication use for the treatment of diabetes in obese individuals Sarah M. Gray · Kevin W. Aylor · Eugene J. Barrett · Eugene J. Barrett
Neurodegeneration in diabetic retinopathy: Does it really matter? F. Feron · L. Salle-TeyssiSres · M. Laloi-Michelin · T. Vidal-Trecan · H. Jacquier · E. Lecorche · F. Mougari · A. Lopes · D. Chopin · P. O. Sellier · J. D. Laredo · J. P. Riveline · F. Mauvais-Jarvis · J. F. Gautier · J. P. Kevorkian · J. P. Kevorkian
SLC30A8 polymorphism and BMI complement HLA-A*24 as risk factors for poor graft function in islet allograft recipients Lena Sjöberg · Lena Sjöberg · Risto Kaaja · Risto Kaaja · Mika Gissler · Mika Gissler · Jaakko Tuomilehto · Jaakko Tuomilehto · Aila Tiitinen · Janne Pitkäniemi · Janne Pitkäniemi
Diabetic cardiomyopathy: a hyperglycaemia- and insulin-resistance-induced heart disease Graham Rena · D. Grahame Hardie · Ewan R. Pearson · Ewan R. Pearson
The role of structured education in the management of hypoglycaemia N. N. Rudovich · O. Pivovarova · J. Mazuch · S. Wendt · N. Tuvia · M. Kruse · V. Nikiforova · V. Murahovschi · Alexander Erban · A. Mosig · C. Sticht · Oe Goegebakan · Lothar Willmitzer · A. Kramer · A. F. Pfeiffer · A. F. Pfeiffer
Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study Khaled Elmasry · Ahmed S. Ibrahim · Heba Saleh · Nehal M. Elsherbiny · Sally Elshafey · Khaled A. Hussein · Mohamed Al-Shabrawey · Mohamed Al-Shabrawey
Impaired hypoglycaemia awareness in type 1 diabetes: lessons from the lab Catherine Crofts · Kenneth H. Brookler · George Henderson · George Henderson
Role of endoplasmic reticulum stress in 12/15-lipoxygenase-induced retinal microvascular dysfunction in a mouse model of diabetic retinopathy Jannie Nielsen · Jannie Nielsen · Adam Hulman · Daniel R. Witte · Daniel R. Witte
Spousal cardiometabolic risk factors and incidence of type 2 diabetes: a prospective analysis from the English Longitudinal Study of Ageing Ronald Ching Wan Ma · Ronald Ching Wan Ma
Prospective evaluation of insulin and incretin dynamics in obese adults with and without diabetes for 2 years after Roux-en-Y gastric bypass Nurah M. Hammoud · Gerard H.A. Visser · Lenie van Rossem · Douwe H. Biesma · Jan M. Wit · Harold W. de Valk · Harold W. de Valk
Long-term BMI and growth profiles in offspring of women with gestational diabetes Kenneth Verboven · Dominique Hansen · J.-W. van Dijk · L.J.C. van Loon · L.J.C. van Loon
Coxsackievirus B1 infections are associated with the initiation of insulin-driven autoimmunity that progresses to type 1 diabetes Camilla Sortsø · Anastasija Komkova · Annelli Sandbæk · Simon J. Griffin · Martha Emneus · Torsten Lauritzen · Rebecca K. Simmons · Rebecca K. Simmons
Effect of screening for type 2 diabetes on healthcare costs: a register-based study among 139,075 individuals diagnosed with diabetes in Denmark between 2001 and 2009 Lorenzo Piemonti · Eelco J.P. de Koning · Thierry Berney · Jon S. Odorico · James F. Markmann · Peter G. Stock · Michael R. Rickels · Michael R. Rickels
Defining outcomes for beta cell replacement therapy: a work in progress Guntram Schernthaner · Marie Helene Schernthaner-Reiter · Marie Helene Schernthaner-Reiter
Diabetes in the older patient: heterogeneity requires individualisation of therapeutic strategies Rafael Simó · Alan W. Stitt · Thomas W. Gardner · Thomas W. Gardner
The novel adipokine WISP1 associates with insulin resistance and impairs insulin action in human myotubes and mouse hepatocytes Altamash Shaikh · Altamash Shaikh
IL-2 antibodies in type 1 diabetes and during IL-2 therapy Andreas Stomby · Mats Ryberg · Michael Svensson · Jon Hauksson · Tommy Olsson · Tommy Olsson
Vegf-A mRNA transfection as a novel approach to improve mouse and human islet graft revascularisation Esra Karakose · Courtney Ackeifi · Peng Wang · Andrew F. Stewart · Andrew F. Stewart
Advances in drug discovery for human beta cell regeneration Raija Lithovius · Daniel Gordin · Carol Forsblom · Markku Saraheimo · Valma Harjutsalo · Per-Henrik Groop · Per-Henrik Groop
The DPP-4 inhibitor vildagliptin impacts the gut microbiota and prevents disruption of intestinal homeostasis induced by a Western diet in mice Subodh Verma · C. David Mazer · David Fitchett · Silvio E. Inzucchi · Egon Pfarr · Jyothis T. George · Bernard Zinman · Bernard Zinman
Empagliflozin reduces cardiovascular events, mortality and renal events in participants with type 2 diabetes after coronary artery bypass graft surgery: subanalysis of the EMPA-REG OUTCOME® randomised trial Jan Bolinder · Per Oskarsson · Ramiro Antuna · P. Geelhoed-Duijvestijn · Jens Krӧger · Raimund Weitgasser · Raimund Weitgasser
Nuts as a replacement for carbohydrates in the diabetic diet: a reanalysis of a randomised controlled trial Rami Al Batran · Keshav Gopal · Mackenzie D. Martin · Kim L. Ho · Malak Almutairi · Hanin Aburasayn · Farah Eaton · Jonathan E. Campbell · John R. Ussher · John R. Ussher
Flash glucose monitoring: objective, not self-referential, outcomes are needed. Reply to Warren RE [letter] Anne-Sofie Graae · Mette Hollensted · Julie Tonsgaard Kloppenborg · Yuvaraj Mahendran · Theresia M. Schnurr · Emil V. Appel · Johanne Rask · Tenna Ruest Haarmark Nielsen · Mia Østergaard Johansen · Allan Linneberg · Allan Linneberg · Allan Linneberg · Marit E. Jørgensen · Marit E. Jørgensen · Niels Grarup · Haja N. Kadarmideen · Birgitte Holst · Oluf Pedersen · Jens-Christian Holm · Torben Hansen · Torben Hansen
Skeletal muscle-specific Cre recombinase expression, controlled by the human α-skeletal actin promoter, improves glucose tolerance in mice fed a high-fat diet Elisabeth Kemter · M. Schaefer · Christian M. Cohrs · Yuri Ivashchenko · K. Steinmeyer · Marion Schuster · A. Wuensch · Mayuko Kurome · Barbara Kessler · Valeri Zakhartchenko · Matthias Loehn · Jochen Seissler · Stephan Speier · Anke Schulte · Eckhard Wolf · Eckhard Wolf
An adult-based insulin resistance genetic risk score associates with insulin resistance, metabolic traits and altered fat distribution in Danish children and adolescents who are overweight or obese Wendy Powell · Stephanie J. Hanna · Claire N. Hocter · Emma Robinson · Joanne Davies · Gareth Dunseath · Stephen Luzio · Daniel Farewell · Li Wen · Colin Mark Dayan · David A. Price · Kristin Ladell · F. Susan Wong · F. Susan Wong
Loss of CXCR3 expression on memory B cells in individuals with long-standing type 1 diabetes Vishal A. Salunkhe · Rajakrishnan Veluthakal · Steven E. Kahn · Debbie C. Thurmond · Debbie C. Thurmond
A selective CD28 antagonist and rapamycin synergise to protect against spontaneous autoimmune diabetes in NOD mice Yasuaki Hayashino · Shintaro Okamura · Satoru Tsujii · Hitoshi Ishii · Hitoshi Ishii
Multiplex proteomics for prediction of major cardiovascular events in type 2 diabetes Marta Olivares · Audrey M. Neyrinck · Sarah A. Pötgens · Martin Beaumont · Nuria Salazar · Patrice D. Cani · Laure B. Bindels · Nathalie M. Delzenne · Nathalie M. Delzenne
Day-to-day fasting glycaemic variability in DEVOTE: associations with severe hypoglycaemia and cardiovascular outcomes (DEVOTE 2) Mirian Ueno · José B.C. Carvalheira · Rachel L. G. S. Oliveira · Lício A. Velloso · M. J. A. Saad · M. J. A. Saad
Discordant association of the CREBRF rs373863828 A allele with increased BMI and protection from type 2 diabetes in Māori and Pacific (Polynesian) people living in Aotearoa/New Zealand Olga Gornik · Tamara Pavić · A Juszczak · E Pape-Medvidovic · Amanda J. Bennett · A L Goyn · Mark McCarthy · Gordan Lauc · Katharine R. Owen · Katharine R. Owen
Folate treatment of pregnant rat dams abolishes metabolic effects in female offspring induced by a paternal pre-conception unhealthy diet N H Ng · X Sim · J K Rundle · A Raimondo · A Mahajan · A L Gloyn · Investigator Magic. · Investigator Magic.
Endocrine-disrupting chemicals and risk of diabetes: an evidence-based review Ronald C.W. Ma · Ronald C.W. Ma
Correction to: Epidemiology of diabetes and diabetic complications in China Greta J. Boersma · Kerstin Heurling · Maria J. Pereira · Emil Johansson · Mark Lubberink · Joey Lau Börjesson · Petros Katsogiannos · Stanko Skrtic · Joel Kullberg · Håkan Ahlström · Jan W. Eriksson · Jan W. Eriksson
Evaluation of anti-insulin receptor antibodies as potential novel therapies for human insulin receptoropathy using cell culture models Andreas Stomby · Maria Waling · Andreas Isaksson · Ingegerd Söderström · Mats Ryberg · Michael Svensson · Jon Hauksson · Tommy Olsson · Tommy Olsson
A heterogeneous response of liver and skeletal muscle fat to the combination of a Paleolithic diet and exercise in obese individuals with type 2 diabetes: a randomised controlled trial Kirstine N. Bojsen-Møller · M. S. Svane · Carsten Dirksen · Nils B. Jørgensen · I. H. Thorius · Viggo B. Kristiansen · B. Hartmann · Jens J. Holst · N. R. Jorgensen · J. E. B. Jensen · S. Madsbad · S. Madsbad
Community-based pre-pregnancy care programme improves pregnancy preparation in women with pregestational diabetes Laurits J. Holm · Lars Krogvold · Lars Krogvold · Jane P. Hasselby · Simranjeet Kaur · Laura A. Claessens · Laura A. Claessens · Mark A. Russell · Clayton E. Mathews · Kristian F. Hanssen · Kristian F. Hanssen · Noel G. Morgan · Bobby P. C. Koeleman · Bart O. Roep · Bart O. Roep · Ivan C. Gerling · Flemming Pociot · Knut Dahl-Jørgensen · Knut Dahl-Jørgensen · Karsten Buschard · Karsten Buschard
Decreased VMAT2 in the pancreas of humans with type 2 diabetes mellitus measured in vivo by PET imaging Angela Sheu · Yixian Chan · Angela Ferguson · Mohammad B. Bakhtyari · Wendy Hawke · Christopher White · Christopher White · Yuk Fun Chan · Patrick J. Bertolino · Patrick J. Bertolino · Heng G. Woon · Umaimainthan Palendira · Umaimainthan Palendira · Frederic Sierro · Frederic Sierro · Sue Mei Lau · Sue Mei Lau · Sue Mei Lau
Protective role of the ELOVL2/docosahexaenoic acid axis in glucolipotoxicity-induced apoptosis in rodent beta cells and human islets Jan W. Eriksson · Per Lundkvist · C. Sjöström · Petros Katsogiannos · Maria J. Pereira · Eva Johnsson · Eva Johnsson
A proinflammatory CD4 + T cell phenotype in gestational diabetes mellitus Paul Welsh · Naomi Rankin · Qiang Li · Patrick B. Mark · Peter Würtz · Mika Ala-Korpela · Michel Marre · Michel Marre · Michel Marre · Neil Poulter · P. Hamet · P. Hamet · John Chalmers · Mark Woodward · Mark Woodward · Mark Woodward · Naveed Sattar · Naveed Sattar
The Adolescent Cardio-Renal Intervention Trial (AdDIT): retinal vascular geometry and renal function in adolescents with type 1 diabetes Shiue-Cheng Tang · Luc Baeyens · Chia-Ning Shen · Shih-Jung Peng · Hung-Jen Chien · David W. Scheel · Chester E. Chamberlain · Michael S. German · Michael S. German
Rates of glycaemic deterioration in a real-world population with type 2 diabetes M. B. Dommerholt · Derek A. Dionne · Daria Hutchinson · Janine K. Kruit · James D. Johnson · James D. Johnson
Basal fatty acid oxidation increases after recurrent low glucose in human primary astrocytes Takao Nammo · Haruhide Udagawa · Nobuaki Funahashi · Miho Kawaguchi · Takashi Uebanso · Masaki Hiramoto · Wataru Nishimura · Kazuki Yasuda · Kazuki Yasuda
SIRT6-mediated transcriptional suppression of Txnip is critical for pancreatic beta cell function and survival in mice Laura Jackisch · Warunee Kumsaiyai · Jonathan D. Moore · Nasser M. Al-Daghri · Ioannis Kyrou · Ioannis Kyrou · Thomas M. Barber · Thomas M. Barber · Harpal S. Randeva · S. Kumar · Gyanendra Tripathi · Gyanendra Tripathi · Philip G. McTernan · Philip G. McTernan · Philip G. McTernan
Short-term progression of cardiometabolic risk factors in relation to age at type 2 diabetes diagnosis: a longitudinal observational study of 100,606 individuals from the Swedish National Diabetes Register A. Di Franco · Giulia Cantini · Laura Raimondi · Edoardo Mannucci · Michaela Luconi · Michaela Luconi
Dynamics of adipose tissue turnover in human metabolic health and disease Anthony W. Russell · Maria Donald · Samantha J. Borg · Jianzhen Zhang · L. Burridge · Robert S. Ware · Nelufa Begum · H. David McIntyre · Claire Jackson · Claire Jackson
Prognostic value of plasma MR-proADM vs NT-proBNP for heart failure in people with type 2 diabetes: the SURDIAGENE prospective study María Luisa Villanueva-Peñacarrillo · María Luisa Villanueva-Peñacarrillo
Lipid environment induces ER stress, TXNIP expression and inflammation in immune cells of individuals with type 2 diabetes Helena Elding Larsson · Kristian Lynch · Maria Lönnrot · Michael J. Haller · Åke Lernmark · William Hagopian · Jin Xiong She · Olli Simell · Jorma Toppari · Anette-G. Ziegler · Beena Akolkar · Jeffrey P. Krischer · Marian Rewers · Heikki Hyöty · Heikki Hyöty
Differential effects of age and sex on insulin sensitivity and body composition in adolescent offspring of women with type 1 diabetes: results from the EPICOM study Alix Besançon · Alix Besançon · Alix Besançon · Tania Goncalves · Tania Goncalves · Tania Goncalves · Fabrice Valette · Fabrice Valette · Fabrice Valette · Mattias S. Dahllöf · Thomas Mandrup-Poulsen · Lucienne Chatenoud · Lucienne Chatenoud · Lucienne Chatenoud · Sylvaine You · Sylvaine You · Sylvaine You · Sylvaine You
FAK tyrosine phosphorylation is regulated by AMPK and controls metabolism in human skeletal muscle M. Yang · M. Kimura · C. Ng · S. Keshvari · J. He · J. L. Barclay · Jonathan P. Whitehead · Jonathan P. Whitehead
Pandemrix® vaccination is not associated with increased risk of islet autoimmunity or type 1 diabetes in the TEDDY study children Carolien Ruijgrok · Jacqueline M. Dekker · Joline W.J. Beulens · Ingeborg A. Brouwer · Veerle M.H. Coupé · Martijn W. Heymans · Femke P. C. Sijtsma · David J. Mela · Peter L. Zock · Margreet R. Olthof · Marjan Alssema · Marjan Alssema
Oral histone deacetylase inhibitor synergises with T cell targeted immunotherapy to preserve beta cell metabolic function and induce stable remission of new-onset autoimmune diabetes in NOD mice Jeremy Walker · Helen M. Colhoun · Shona Livingstone · Rory J. McCrimmon · John R. Petrie · Naveed Sattar · Sarah H. Wild · Sarah H. Wild
Size and shape of the associations of glucose, HbA1c, insulin and HOMA-IR with incident type 2 diabetes: the Hoorn Study S A Mostafa · R L Coleman · O F Agbaje · Alastair Gray · R R Holman · M A Bethel · M A Bethel
Type 2 diabetes, socioeconomic status and life expectancy in Scotland (2012–2014): a population-based observational study M. Reijrink · S. A. De Boer · D. S. Spoor · Joop D. Lefrandt · H. J. Lambers Heerspink · Ronald Boellaard · Marcel J. W. Greuter · Riemer H. J. A. Slart · Douwe J. Mulder · Douwe J. Mulder
Aortic stiffness and ambulatory blood pressure as predictors of diabetic kidney disease: a competing risks analysis from the Rio de Janeiro Type 2 Diabetes Cohort Study Isabel Ferreira · Peter Hovind · Casper G. Schalkwijk · Hans-Henrik Parving · Coen D. A. Stehouwer · Peter Rossing · Peter Rossing · Peter Rossing
Association of maternal exposures with adiposity at age 4/5 years in white British and Pakistani children: findings from the Born in Bradford study Fengmin Li · Jian Yang · Jian Yang · Van Anthony M. Villar · Van Anthony M. Villar · Laureano D. Asico · Laureano D. Asico · Xiaobo Ma · Ines Armando · Ines Armando · Hironobu Sanada · Minoru Yoneda · Robin A. Felder · Pedro A. Jose · Pedro A. Jose · Xiaoyan Wang · Xiaoyan Wang · Xiaoyan Wang
Biomarkers of inflammation and endothelial dysfunction as predictors of pulse pressure and incident hypertension in type 1 diabetes: a 20-year life-course study in an inception cohort Maria Lönnrot · Kristian Lynch · Helena Elding Larsson · Åke Lernmark · Marian Rewers · Carina Törn · Brant R. Burkhardt · Thomas Briese · William Hagopian · Jin Xiong She · Olli Simell · Jorma Toppari · Jorma Toppari · Anette-G. Ziegler · Beena Akolkar · Jeffrey P. Krischer · Heikki Hyöty · Heikki Hyöty
Loss of Renal SNX5 Results in Impaired IDE Activity and Insulin Resistance in Mice Jason Gurney · James Stanley · Steve York · Dieter Rosenbaum · Diana Sarfati · Diana Sarfati
Correction to: Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity: the TEDDY study S. M. Schmid · Stefanie Lanzinger · Wolfram Karges · Julia K. Mader · Jochen Seufert · D. Bergis · S. Zimny · Joachim Rosenbauer · W. Kerner · Reinhard W. Holl · M. Hummel · M. Hummel
Diabetic retinopathy: hyperglycaemia, oxidative stress and beyond Clare B. Kelly · Clare B. Kelly · Michelle B. Hookham · Jeremy Y. Yu · Jeremy Y. Yu · Samuel M. Lockhart · Mei Du · Alicia J. Jenkins · Alicia J. Jenkins · Alison Nankervis · Kristian F. Hanssen · Kristian F. Hanssen · Tore Henriksen · Satish K. Garg · Samar M. Hammad · James A. Scardo · Christopher E. Aston · Christopher Patterson · Timothy J. Lyons · Timothy J. Lyons · Timothy J. Lyons
The chicken or the egg? Does glycaemic control predict cognitive function or the other way around? I Akoumianakis · L Herdman · M Margaritis · F Sanna · R Sayeed · M Petrou · P Wohlfart · N Tennagels · Keith M. Channon · C Antoniades · C Antoniades
Gian Franco Bottazzo, 1946–2017 Abigail C Lay · Jenny A. Hurcombe · Virginie M.S. Betin · Fern Barrington · Ruth Rollason · Lan Ni · Lawrence Gillam · Grace M. E. Pearson · Mette Viberg Østergaard · Mette Viberg Østergaard · Hellyeh Hamidi · Rachel Lennon · Gavin I. Welsh · Richard J M Coward · Richard J M Coward
Enteroendocrine K and L cells in healthy and type 2 diabetic individuals Heba M. Ismail · Ping Xu · Ingrid Libman · Dorothy J. Becker · Jennifer B. Marks · Jay S. Skyler · Jerry P. Palmer · Jay M. Sosenko · Jay M. Sosenko
Devoting attention to glucose variability and hypoglycaemia in type 2 diabetes Toma Keser · Ivan Gornik · Frano Vučković · Najda Selak · Tamara Pavić · Edita Lukić · Ivan Gudelj · Hrvoje Gasparovic · Bojan Biocina · Therese Tilin · Annika Wennerström · Satu Männistö · Veikko Salomaa · Aki S. Havulinna · Wei Wang · Wei Wang · James F. Wilson · Nishi Charutvedi · Markus Perola · Harry Campbell · Gordan Lauc · Olga Gornik · Olga Gornik
Medicalising pregnancy with new diagnostic criteria for gestational diabetes mellitus: do we need more evidence? Reply to Venkataraman H and Saravanan P [letter] Paz L. D. Ruiz · Paz L. D. Ruiz · Paz L. D. Ruiz · German Tapia · Inger Johanne Bakken · Siri E. Håberg · Olav Hungnes · Hanne L. Gulseth · Hanne L. Gulseth · Lars C. Stene · Lars C. Stene
Insights uncovered from experiencing a rise in the incidence of gestational diabetes at a Melbourne hospital. Reply to Ng E, Neff M, Sztal-Mazer S [letter] Mustafa Tosur · Susan Geyer · Henry Rodriguez · Ingrid Libman · David A. Baidal · Maria J. Redondo · Maria J. Redondo
Pandemic influenza and subsequent risk of type 1 diabetes: a nationwide cohort study Anna Erzsébet Körei · M Kempler · Z Putz · O Vagi · I Istenes · Adam G. Tabak · Spallone · P. Kempler · P. Kempler
Ethnic differences in progression of islet autoimmunity and type 1 diabetes in relatives at risk Abass Alavi · Thomas Werner · Thomas Werner
Futility of attempts to detect and quantify beta cells by PET imaging in the pancreas: why it is time to abandon the approach Yang Yu · Yang Yu · Anissa Gamble · Rena Pawlick · Andrew R. Pepper · Bassem Salama · Derek Toms · Derek Toms · Golsa Razian · Golsa Razian · Cara Ellis · Antonio Bruni · Boris Gala-Lopez · Jia Lulu Lu · Jia Lulu Lu · Heather Vovko · Heather Vovko · Cecilia Chiu · Cecilia Chiu · Shaaban Abdo · Shaaban Abdo · Tatsuya Kin · Greg Korbutt · A. M. James Shapiro · Mark Ungrin · Mark Ungrin · Mark Ungrin
Medicalising pregnancy with new diagnostic criteria for gestational diabetes mellitus: do we need more evidence? Jan W. Eriksson · Per Lundkvist · Per-Anders Jansson · Lars Johansson · Mats Kvarnström · Linda Moris · Tasso Miliotis · Gun-Britt Forsberg · Ulf Risérus · Lars Lind · Jan Oscarsson · Jan Oscarsson
Bioengineered human pseudoislets form efficiently from donated tissue, compare favourably with native islets in vitro and restore normoglycaemia in mice Shanshan Du · Xiaoyan Wu · Tianshu Han · Wei Duan · Lei Liu · Jiayue Qi · Yucun Niu · Lixin Na · Changhao Sun · Changhao Sun
Effects of dapagliflozin and n-3 carboxylic acids on non-alcoholic fatty liver disease in people with type 2 diabetes: a double-blind randomised placebo-controlled study Alexandra K. Lee · Andreea M. Rawlings · Clare J. Lee · Alden L. Gross · Elbert S. Huang · A. Richey Sharrett · Josef Coresh · Elizabeth Selvin · Elizabeth Selvin
Dietary manganese and type 2 diabetes mellitus: two prospective cohort studies in China Haiyun Qi · Per Mose Nielsen · Marie Schroeder · Lotte Bonde Bertelsen · Fredrik Palm · Christoffer Laustsen · Christoffer Laustsen
Severe hypoglycaemia, mild cognitive impairment, dementia and brain volumes in older adults with type 2 diabetes: the Atherosclerosis Risk in Communities (ARIC) cohort study A Juszczak · Tim James · Timothy J. McDonald · Martine Vaxillaire · Iwar Klimes · Maciej T. Malecki · T. Hansen · Pål R. Njølstad · Tiinamaija Tuomi · Anna L. Gloyn · Mark McCarthy · K R Owen · K R Owen
Acute renal metabolic effect of metformin assessed with hyperpolarised MRI in rats Christian S. Göbl · Latife Bozkurt · Andrea Tura · Michael Leutner · Laura Andrei · Lukas Fahr · Peter Husslein · Wolfgang Eppel · Alexandra Kautzky-Willer · Alexandra Kautzky-Willer
α-linolenic acid supplementation prevents exercise-induced improvements in white adipose tissue mitochondrial bioenergetics and whole-body glucose homeostasis in obese Zucker rats Henning Hvid · Mikkel S. Jørgensen · Niels Blume · Rita Slaaby · Anne Lützen · Bo Falck Hansen · Bo Falck Hansen
Decreasing incidence of pharmacologically and non-pharmacologically treated type 2 diabetes in Norway: a nationwide study Adina Leiah Feldman · Simon J. Griffin · Eva Fhärm · Margareta Norberg · Patrik Wennberg · Lars Weinehall · Olov Rolandsson · Olov Rolandsson
Activation of insulin receptors and IGF-1 receptors in COLO-205 colon cancer xenografts by insulin and insulin analogue X10 does not enhance growth under normo- or hypoglycaemic conditions Miriam Cnop · Miriam Cnop · Tomasz Klupa · Nikolaos Tentolouris · Anna Novials · Rémy Burcelin · Mischa van Eimeren · Mischa van Eimeren
Risk of lower limb amputation in a national prevalent cohort of patients with diabetes Akiko Kishi Svensson · Akiko Kishi Svensson · T. Svensson · T. Svensson · T. Svensson · Mariusz Kitlinski · Peter Almgren · Gunnar Engström · Peter Nilsson · Olle Melander · Olle Melander
Incident diabetes mellitus may explain the association between sleep duration and incident coronary heart disease Shiue-Cheng Tang · Chia-Ning Shen · Chia-Ning Shen · Pei Yu Lin · Pei Yu Lin · Shih Jung Peng · Hung Jen Chien · Ya Hsien Chou · Chester E. Chamberlain · Pankaj J. Pasricha · Pankaj J. Pasricha
DNA methylation markers associated with type 2 diabetes, fasting glucose and HbA(1c) levels: a systematic review and replication in a case-control sample of the Lifelines study O F Agbaje · R L Coleman · Andrew T. Hattersley · E Z Pearson · R R Holman · R R Holman
HbA1c is associated with altered expression in blood of cell cycle- and immune response-related genes Sarah H. Koning · Jelmer J. van Zanden · Klaas Hoogenberg · Helen L. Lutgers · Alberdina W. Klomp · Fleurisca J. Korteweg · Aren J. van Loon · Bruce H. R. Wolffenbuttel · Paul P. van den Berg · Paul P. van den Berg
Translating aetiological insight into sustainable management of type 2 diabetes Louise A. Donnelly · K Gardner · R L Coleman · Naveed Sattar · Andrew T. Hattersley · R R Holman · Ewan R. Pearson · Ewan R. Pearson
Clinical and metabolic features of the randomised controlled Diabetes Remission Clinical Trial (DiRECT) cohort Manuel Sanchez · Manuel Sanchez · Ronan Roussel · Ronan Roussel · Samy Hadjadj · Samy Hadjadj · Abdul Moutairou · Michel Marre · Michel Marre · Gilberto Velho · Kamel Mohammedi · Kamel Mohammedi
New diagnostic criteria for gestational diabetes mellitus and their impact on the number of diagnoses and pregnancy outcomes Paul W. Franks · Yuning Chen · Angela C. Estampador · Maria Keller · Alaitz Poveda · Jonathan Dalla-Riva · Frida Renström · Azra Kurbasic · Tibor V. Varga · Tibor V. Varga
Plasma concentrations of 8-hydroxy-2′-deoxyguanosine and risk of kidney disease and death in individuals with type 1 diabetes Virginia M. Stone · Virginia M. Stone · Minna M. Hankaniemi · Emma Svedin · Amirbabak Sioofy-Khojine · Sami Oikarinen · Heikki Hyöty · Olli H. Laitinen · Vesa P. Hytönen · Malin Flodström-Tullberg · Malin Flodström-Tullberg · Malin Flodström-Tullberg
Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes Yun Huang · Xin Chen · Xiaohong Chen · Yu Feng · Heming Guo · Sicheng Li · Ting Dai · Rong Jiang · Xiaoyan Zhang · Chen Fang · Ji Hu · Ji Hu
A Coxsackievirus B vaccine protects against virus-induced diabetes in an experimental mouse model of type 1 diabetes Mats Ryberg · Caroline Mellberg · Bernt Lindahl · Christel Larsson · Jens J. Holst · Tommy Olsson · Tommy Olsson
Angiopoietin-like protein 8 in early pregnancy improves the prediction of gestational diabetes Sofie Persson · Gisela Dahlquist · Ulf-G. Gerdtham · Katarina Steen Carlsson · Katarina Steen Carlsson
Lower risk of dementia with pioglitazone, compared with other second-line treatments, in metformin-based dual therapy: a population-based longitudinal study Michael Gejl · Albert Gjedde · Birgitte Brock · Arne Møller · Eelco van Duinkerken · Eelco van Duinkerken · Hanne Haahr · Charlotte T. Hansen · Pei-Ling Chu · Kirstine Stender-Petersen · Jørgen Rungby · Jørgen Rungby · Jørgen Rungby
Why childhood-onset type 1 diabetes impacts labour market outcomes: a mediation analysis R L Coleman · Alastair Gray · U C Broedl · D Fitchett · J T George · Woerle H-J. · Bernard Zinman · R R Holman · R R Holman
Effects of hypoglycaemia on working memory and regional cerebral blood flow in type 1 diabetes: a randomised, crossover trial Frederico G.S. Toledo · Darcy L. Johannsen · Jeffrey D. Covington · Sudip Bajpeyi · Sudip Bajpeyi · Bret H. Goodpaster · Kevin E. Conley · Eric Ravussin · Eric Ravussin
Impact of prolonged overfeeding on skeletal muscle mitochondria in healthy individuals Robert G. Josse · Sumit R. Majumdar · Yinggan Zheng · John B. Buse · Jennifer B. Green · Keith D. Kaufman · Eric D. Peterson · R R Holman · Paul W. Armstrong · Grp Tecoss. · Grp Tecoss.
Early deficits in insulin secretion, beta cell mass and islet blood perfusion precede onset of autoimmune type 1 diabetes in BioBreeding rats Davis Tme. · H Mulder · Yuliya Lokhnygina · E Standl · Eric D. Peterson · R R Holman · Grp Tecoss. · Grp Tecoss.
Combinatorial detection of autoreactive CD8+ T cells with HLA-A2 multimers: a multi-centre study by the Immunology of Diabetes Society T Cell Workshop Alastair Gray · Jose Leal · Shelby D. Reed · Yi-Ju Li · Felicia L. Graham · Jennifer B. Green · Keith D. Kaufman · Larry Radican · Joakim Alfredsson · John B. Buse · A Riefflin · F. Van de Werf · Eric D. Peterson · R R Holman · R R Holman
Increasing risk of psychiatric morbidity after childhood onset type 1 diabetes: a population-based cohort study M A Nauck · K S Pieper · Yuliya Lokhnygina · D K McGuire · Eric D. Peterson · R R Holman · Grp Tecoss. · Grp Tecoss.
Class effects of SGLT2 inhibitors in mouse cardiomyocytes and hearts: inhibition of Na+/H+ exchanger, lowering of cytosolic Na+ and vasodilation Jonathan Y. Xia · Jonathan Y. Xia · Kai Sun · Kai Sun · Chelsea Hepler · Alexandra L. Ghaben · Rana K. Gupta · Yu A. An · William L. Holland · Thomas S. Morley · Andrew C. Adams · Ruth Gordillo · Christine M. Kusminski · Philipp E. Scherer · Philipp E. Scherer
Correction to: Increased plasma N-glycome complexity is associated with higher risk of type 2 diabetes Roderick C. Slieker · Roderick C. Slieker · Amber A. W. A. van der Heijden · Nienke van Leeuwen · Hailiang Mei · Giel Nijpels · Joline W.J. Beulens · Joline W.J. Beulens · Leen M. ‘t Hart · Leen M. ‘t Hart · Leen M. ‘t Hart
Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population Adam D. Farmer · Adam D. Farmer · Anne Grave Pedersen · Birgitte Brock · Poul Erik Jakobsen · Jesper Karmisholt · Sahar Mohammed · S. Mark Scott · Asbjørn Mohr Drewes · Christina Brock · Christina Brock
Exercise training response heterogeneity: statistical insights Toma Keser · Ivan Gornik · Frano Vučković · Najda Selak · Tamara Pavić · Edita Lukić · Ivan Gudelj · Hrvoje Gasparovic · Bojan Biocina · Therese Tilin · Annika Wennerström · Satu Männistö · Veikko Salomaa · Aki S. Havulinna · Wei Wang · James F. Wilson · Nish Chaturvedi · Markus Perola · Harry Campbell · Gordan Lauc · Olga Gornik · Olga Gornik
Pancreatic neuro-insular network in young mice revealed by 3D panoramic histology Gareth S. D. Purvis · Fausto Chiazza · Jianmin Chen · Rodrigo Azevedo-Loiola · Lukas Martin · Dennis H. M. Kusters · Chris Reutelingsperger · Nikolaos Fountoulakis · Luigi Gnudi · Muhammed M. Yaqoob · Massimo Collino · Christoph Thiemermann · Egle Solito · Egle Solito
Considerations and guidelines for mouse metabolic phenotyping in diabetes research Andrew Farmer · Lee M-M. · Jason Oke · A Reutens · J Shaw · R R Holman · R R Holman
Maternal obesity as a risk factor for early childhood type 1 diabetes: a nationwide, prospective, population-based case-control study Nicola M. McKeown · Hassan S. Dashti · Hassan S. Dashti · Hassan S. Dashti · Jiantao Ma · Danielle E. Haslam · Jessica C. Kiefte-de Jong · Jessica C. Kiefte-de Jong · Caren E. Smith · Toshiko Tanaka · Mariaelisa Graff · Rozenn N. Lemaitre · Denis Rybin · Emily Sonestedt · Alexis C. Frazier-Wood · Dennis O. Mook-Kanamori · Yanping Li · Carol A. Wang · Elisabeth T.M. Leermakers · Vera Mikkilä · Vera Mikkilä · Kristin L. Young · Kenneth J. Mukamal · L. Adrienne Cupples · L. Adrienne Cupples · Christina-Alexandra Schulz · Tzu An Chen · Ruifang Li-Gao · Tao Huang · Wendy H. Oddy · Olli T. Raitakari · Olli T. Raitakari · Kenneth Rice · James B. Meigs · James B. Meigs · Ulrika Ericson · Lyn M. Steffen · Frits R. Rosendaal · Albert Hofman · Mika Kähönen · Bruce M. Psaty · Bruce M. Psaty · Louise Brunkwall · André G. Uitterlinden · Jorma Viikari · Jorma Viikari · David S. Siscovick · Ilkka Seppälä · Kari E. North · Dariush Mozaffarian · Josée Dupuis · Josée Dupuis · Marju Orho-Melander · Stephen S. Rich · Renée de Mutsert · Lu Qi · Craig E. Pennell · Oscar H. Franco · Terho Lehtimäki · Mark A. Herman · Mark A. Herman
Three-question set from Michigan Neuropathy Screening Instrument adds independent prognostic information on cardiovascular outcomes: analysis of ALTITUDE trial Lily Agrawal · Nasrin Azad · Gideon D. Bahn · Ling Ge · Rodney A. Hayward · Domenic J. Reda · Nicholas V. Emanuele · Nicholas V. Emanuele
Annexin A1 attenuates microvascular complications through restoration of Akt signalling in a murine model of type 1 diabetes Mengge Zhou · Jing Liu · Yue Qi · Miao Wang · Ying Wang · Fan Zhao · Yongchen Hao · Dong Zhao · Dong Zhao
Sugar-sweetened beverage intake associations with fasting glucose and insulin concentrations are not modified by selected genetic variants in a ChREBP-FGF21 pathway: a meta-analysis Claudiane Guay · Janine K. Kruit · S. Rome · S. Rome · Véronique Menoud · Guido Sebastiani · Christian Boitard · Christian Boitard · Francesco Dotta · Romano Regazzi · Romano Regazzi
Long-term follow-up of intensive glycaemic control on renal outcomes in the Veterans Affairs Diabetes Trial (VADT) M A Bethel · Samuel S. Engel · J Ding · Robert G. Josse · R R Holman · Grp Tecoss. · Grp Tecoss.
The association between Helicobacter pylori seropositivity and risk of new-onset diabetes: a prospective cohort study Michele Longo · Gregory Alexander Raciti · Federica Zatterale · Luca Parrillo · Antonella Desiderio · Rosa Spinelli · Ann Hammarstedt · Shahram Hedjazifar · Jenny M. Hoffmann · Cecilia Nigro · Paola Mirra · Francesca Fiory · Pietro Formisano · Claudia Miele · Ulf Smith · Francesco Beguinot · Francesco Beguinot
Epigenetic modifications of the Zfp/ZNF423 gene control murine adipogenic commitment and are dysregulated in human hypertrophic obesity Boon How Chew · Rimke C. Vos · R. K.|info:eu-repo Stellato · dai · S. Shariff Ghazali · Mastura Ismail · G. E. H.|info:eu-repo Rutten · G. E. H.|info:eu-repo Rutten
Hospital time prior to death and pancreas histopathology: implications for future studies Francesca Romana Mancini · Aurélie Affret · Courtney Dow · Beverley Balkau · Fabrice Bonnet · Fabrice Bonnet · Marie-Christine Boutron-Ruault · Guy Fagherazzi · Guy Fagherazzi
Associations between birthweight, gestational age at birth and subsequent type 1 diabetes in children under 12: a retrospective cohort study in England, 1998–2012 Huberta E. Hart · K. N. Bontje · G. E. H.|info:eu-repo Rutten · dai · Rimke C. Vos · Rimke C. Vos
Dietary antioxidant capacity and risk of type 2 diabetes in the large prospective E3N-EPIC cohort Rimke C. Vos · L. van Heusden · G. E. H.|info:eu-repo Rutten · dai · dai
Development and characterisation of a novel glucagon like peptide-1 receptor antibody Niina Lietzen · Le T. T. An · Maria K. Jaakkola · Henna Kallionpää · Sami Oikarinen · Juha Mykkänen · Mikael Knip · Riitta Veijola · Jorma Ilonen · Jorma Toppari · Heikki Hyöty · Riitta Lahesmaa · Laura L. Elo · Laura L. Elo
Enterovirus-associated changes in blood transcriptomic profiles of children with genetic susceptibility to type 1 diabetes João M. N. Duarte · F. M. Girault · S. Sonnay · S. Sonnay
Workplace bullying and violence as risk factors for type 2 diabetes: a multicohort study and meta-analysis Roy Taylor · Alison C. Barnes · Alison C. Barnes
Epigenetics in diabetic nephropathy, immunity and metabolism T ALRamah · K Pinel · David Preiss · Naveed Sattar · Jennifer Logue · Paul Welsh · Paul Welsh
Decreasing rates of major lower-extremity amputation in people with diabetes but not in those without: a nationwide study in Belgium M. Rottenkolber · C. Muschet · M. Breier · M Fugmann · V Sacco · M Weise · Cornelia Prehn · Harald Grallert · Martin Bidlingmaier · M. Hrabé de Angelis · J. Seissler · Martin Reincke · Jerzy Adamski · U Ferrari · A Lechner · A Lechner
Metabolic surgery for the treatment of type 2 diabetes in obese individuals J Dennis · William Henley · Michael N. Weedon · Mike Lonergan · L Rodgers · Angus G. Jones · Naveed Sattar · R R Holman · Ewan R. Pearson · Andrew T. Hattersley · B. M. Shields · B. M. Shields
The resident macrophages in murine pancreatic islets are constantly probing their local environment, capturing beta cell granules and blood particles Larissa C. Da Rosa · Larissa C. Da Rosa · Joanne Boldison · Evy De Leenheer · Evy De Leenheer · Joanne Davies · Li Wen · F. Susan Wong · F. Susan Wong
B cell depletion reduces T cell activation in pancreatic islets in a murine autoimmune diabetes model Diego Bailetti · F Sentinelli · L Bertoccini · A Di Costanzo · M Incani · Massimo Arcà · F Leonetti · S Prudente · M Baroni · M Baroni
Insights uncovered from experiencing a rise in the incidence of gestational diabetes at a Melbourne hospital Miguel Ruiz-Canela · Miguel Ruiz-Canela · Marta Guasch-Ferré · Estefanía Toledo · Estefanía Toledo · Clary B. Clish · Cristina Razquin · Cristina Razquin · Liming Liang · Dong D. Wang · Dolores Corella · Dolores Corella · Ramón Estruch · Ramón Estruch · Álvaro Hernáez · Edward Yu · Enrique Gómez-Gracia · Yan Zheng · Fernando Arós · Fernando Arós · Dora Romaguera · Courtney Dennis · Emilio Ros · Emilio Ros · José Lapetra · Lluis Serra-Majem · Christopher Papandreou · Christopher Papandreou · Olga Portolés · Olga Portolés · Montserrat Fitó · Jordi Salas-Salvadó · Jordi Salas-Salvadó · Frank B. Hu · Frank B. Hu · Miguel Ángel Martínez-González · Miguel Ángel Martínez-González
Distribution of IL-1β immunoreactive cells in pancreatic biopsies from living volunteers with new-onset type 1 diabetes: comparison with donors without diabetes and with longer duration of disease Bernd H. Zinselmeyer · Anthony N. Vomund · Brian T. Saunders · Michael W. Johnson · Javier A. Carrero · Emil R. Unanue · Emil R. Unanue
Can insulin response patterns predict metabolic disease risk in individuals with normal glucose tolerance Jonathan Q. Purnell · Geoffrey S. Johnson · Abdus S. Wahed · Chiara Dalla Man · Francesca Piccinini · Claudio Cobelli · Ronald L. Prigeon · Bret H. Goodpaster · David E. Kelley · Myrlene A. Staten · Karen E. Foster-Schubert · David E. Cummings · David R. Flum · Anita P. Courcoulas · Peter J. Havel · Bruce M. Wolfe · Bruce M. Wolfe
Epidemiology of diabetes and diabetic complications in China Amirbabak Sioofy-Khojine · Jussi Lehtonen · Noora Nurminen · Olli H. Laitinen · Sami Oikarinen · Heini Huhtala · Outi Pakkanen · Tanja Ruokoranta · Minna M. Hankaniemi · Jorma Toppari · Jorma Toppari · Mari Vähä-Mäkilä · Mari Vähä-Mäkilä · Jorma Ilonen · Jorma Ilonen · Riitta Veijola · Mikael Knip · Heikki Hyöty · Heikki Hyöty
Prediction of clamp-derived insulin sensitivity from the oral glucose insulin sensitivity index Lena Bilet · Esther Phielix · T. van de Weijer · A. Gemmink · Madeleen Bosma · Esther Moonen-Kornips · Johanna A. Jörgensen · K. Meijer · M. Hopman · Matthijs K. C. Hesselink · D. M. Ouwens · Vera B. Schrauwen-Hinderling · P. Schrauwen · P. Schrauwen
The impact of hypoglycaemia awareness status on regional brain responses to acute hypoglycaemia in men with type 1 diabetes Tina Hörbelt · Christopher Tacke · Mariya Markova · Daniella Herzfeld de Wiza · Frederique Van de Velde · Marlies Bekaert · Yves Van Nieuwenhove · S Hornemann · Maria Rödiger · Nicole Seebeck · Elisabeth Friedl · Wenke Jonas · G. Hege Thoresen · Oliver Kuss · Anke Rosenthal · Volker Lange · Andreas F.H. Pfeiffer · Annette Schürmann · Bruno Lapauw · Natalia Rudovich · O Pivovarova · D. Margriet Ouwens · D. Margriet Ouwens
Ambulatory blood pressure and arterial stiffness in individuals with type 1 diabetes David J.A. Jenkins · David J.A. Jenkins · Cyril W.C. Kendall · Cyril W.C. Kendall · Cyril W.C. Kendall · Benoît Lamarche · Monica S. Banach · Korbua Srichaikul · Korbua Srichaikul · Edward Vidgen · Edward Vidgen · Sandy Mitchell · Tina Parker · Stephanie Nishi · Stephanie Nishi · Balachandran Bashyam · Balachandran Bashyam · Russell J. de Souza · Russell J. de Souza · Russell J. de Souza · Christopher Ireland · Sathish C. Pichika · Sathish C. Pichika · Sathish C. Pichika · Joseph Beyene · John L. Sievenpiper · John L. Sievenpiper · Robert G. Josse · Robert G. Josse · Robert G. Josse
Activation of GLP-1 receptor signalling alleviates cellular stresses and improves beta cell function in a mouse model of Wolfram syndrome Jose C. Florez · Jose C. Florez · Jose C. Florez
Cognitive function in early and later life is associated with blood glucose in older individuals: analysis of the Lothian Birth Cohort of 1936 Alix Besançon · Alix Besançon · Tania Goncalves · Tania Goncalves · Fabrice Valette · Fabrice Valette · Caroline Mary · Bernard Vanhove · Lucienne Chatenoud · Lucienne Chatenoud · Sylvaine You · Sylvaine You
Novel approaches to restore beta cell function in prediabetes and type 2 diabetes Jens Oellgaard · Jens Oellgaard · Peter Gæde · Peter Rossing · Peter Rossing · Peter Rossing · Rasmus Rørth · Lars Køber · Hans Henrik Parving · Oluf Pedersen · Oluf Pedersen
Reduced risk of heart failure with intensified multifactorial intervention in individuals with type 2 diabetes and microalbuminuria: 21 years of follow-up in the randomised Steno-2 study M. Backmann · Andreas Blutke · S. Krebs · Simone Renner · R. Wanke · H. Blum · Eckhard Wolf · Eckhard Wolf
Association between diabetes distress and all-cause mortality in Japanese individuals with type 2 diabetes: a prospective cohort study (Diabetes Distress and Care Registry in Tenri [DDCRT 18]) Bruce A. Perkins · Bruce A. Perkins · Leif E. Lovblom · Vera Bril · Daniel Scarr · Ilia Ostrovski · Andrej Orszag · Katie Edwards · Nicola Pritchard · Anthony W. Russell · Cirous Dehghani · Danièle Pacaud · Kenneth Romanchuk · Jean K. Mah · Maria Jeziorska · Andrew Marshall · Roni M. Shtein · Rodica Pop-Busui · Stephen I. Lentz · Andrew J.M. Boulton · Mitra Tavakoli · Nathan Efron · Rayaz A. Malik · Rayaz A. Malik
Corneal confocal microscopy for identification of diabetic sensorimotor polyneuropathy: a pooled multinational consortium study Heiner Claessen · Herve Avalosse · Joeri Guillaume · Maria Narres · Tatjana Kvitkina · Werner Arend · Stephan Morbach · Patrick Lauwers · Frank Nobels · Jacques Boly · Chris Van Hul · Kris Doggen · Isabelle Dumont · P Felix · Kristien Van Acker · Andrea Icks · Andrea Icks
Abnormal islet sphingolipid metabolism in type 1 diabetes Lara Bellini · Mélanie Campana · Marta Chacinska · Marco Bugliani · Kelly Meneyrol · Isabelle Hainault · Véronique Lenoir · Véronique Lenoir · Véronique Lenoir · Jessica Denom · Julien Véret · Nadim Kassis · Bernard Thorens · Mark Ibberson · Piero Marchetti · Agnieszka Blachnio-Zabielska · Céline Cruciani-Guglielmacci · Carina Prip-Buus · Carina Prip-Buus · Carina Prip-Buus · Christophe Magnan · Hervé Le Stunff · Hervé Le Stunff · Hervé Le Stunff
Circulating amino acids and the risk of macrovascular, microvascular and mortality outcomes in individuals with type 2 diabetes: results from the ADVANCE trial David Houghton · Timothy Hardy · Christopher J. Stewart · Linda Errington · Christopher P. Day · Michael I. Trenell · Leah Avery · Leah Avery
Exercise training decreases pancreatic fat content and improves beta cell function regardless of baseline glucose tolerance: a randomised controlled trial Leen M. ‘t Hart · Nicole Vogelzangs · M.M.J. van Greevenbroek · C.J.H. van der Kallen · Roderick C. Slieker · Dennis O. Mook-Kanamori · K. Willems van Dijk · J. M. Dekker · G. Nijpels · G. Nijpels
Systematic review assessing the effectiveness of dietary intervention on gut microbiota in adults with type 2 diabetes Kelly Bowden Davies · Victoria S. Sprung · Juliette A. Norman · Andrew Thompson · Katie L. Mitchell · Jason Halford · Jo Harrold · John Wilding · Graham J. Kemp · Daniel J. Cuthbertson · Daniel J. Cuthbertson
Short-term decreased physical activity with increased sedentary behaviour causes metabolic derangements and altered body composition: effects in individuals with and without a first-degree relative with type 2 diabetes Marta Perez-Alcantara · Christian Honoré · Agata Wesolowska-Andersen · Anna L. Gloyn · Mark I. McCarthy · Mattias Hansson · Nicola L. Beer · Martijn van de Bunt · Martijn van de Bunt
Patterns of differential gene expression in a cellular model of human islet development, and relationship to type 2 diabetes predisposition Jian Li · Yong-Ping Lu · Yong-Ping Lu · Oleg Tsuprykov · Ahmed Abdallah Hasan · Ahmed Abdallah Hasan · Christoph Reichetzeder · Mei Tian · Xiao Li Zhang · Qin Zhang · Guo-Ying Sun · Jingli Guo · Jingli Guo · Mohamed M.S. Gaballa · Mohamed M.S. Gaballa · Xiao-Ning Peng · Ge Lin · Ge Lin · Berthold Hocher · Berthold Hocher · Berthold Hocher
Empagliflozin in women with type 2 diabetes and cardiovascular disease – an analysis of EMPA-REG OUTCOME® C. Hawlitschek · U. Ferrari · F. Banning · I. Freibothe · V. Sacco · C. Wichmann · S. Reif · A. Potzel · Cornelia Prehn · N. N. Sommer · H. Hetterich · Jerzy Adamski · Jochen Seissler · A. Lechner · A. Lechner
Acute loss of adipose tissue-derived adiponectin triggers immediate metabolic deterioration in mice David E. Cummings · Francesco Rubino · Francesco Rubino
GIP(3 - 30)NH 2 is an efficacious GIP receptor antagonist in humans: a randomised, double-blinded, placebo-controlled, crossover study Suzy Hope · Bridget A. Knight · Beverley M. Shields · Anita Hill · Pratik Choudhary · W. David Strain · Timothy J. McDonald · Angus G. Jones · Angus G. Jones
Effect of sitagliptin on energy metabolism and brown adipose tissue in overweight individuals with prediabetes: a randomised placebo-controlled trial Susanne M. Cabrera · Samuel Engle · Mary L. Kaldunski · Shuang Jia · Rhonda Geoffrey · Pippa Simpson · Aniko Szabo · Cate Speake · Carla J. Greenbaum · Yi-Guang Chen · Martin J. Hessner · Martin J. Hessner
Serum metabolomic profile of incident diabetes Linda A. Gallo · M. R. Gandhi · E. D. Abel · I. Rubera · M. Tauc · Josephine M. Forbes · Josephine M. Forbes
Global trends in diabetes complications: a review of current evidence Maija Feodoroff · Valma Harjutsalo · Valma Harjutsalo · Carol Forsblom · Per-Henrik Groop · Per-Henrik Groop
Human adipose tissue-derived stromal cells act as functional pericytes in mice and suppress high-glucose-induced proinflammatory activation of bovine retinal endothelial cells Lily Boutens · Rinke Stienstra · Rinke Stienstra
Beta cell function in type 1 diabetes determined from clinical and fasting biochemical variables Jeroen H. P. M. van der Velde · Jeroen H. P. M. van der Velde · Nicolaas C. Schaper · Nicolaas C. Schaper · Coen D. A. Stehouwer · Coen D. A. Stehouwer · Carla J.H. van der Kallen · Carla J.H. van der Kallen · Simone J. S. Sep · Simone J. S. Sep · Miranda T. Schram · Miranda T. Schram · Ronald M. A. Henry · Ronald M. A. Henry · Pieter C. Dagnelie · Simone J. P. M. Eussen · Martien C. J. M. van Dongen · Hans Savelberg · Annemarie Koster · Annemarie Koster
Relation of plasma ceramides to visceral adiposity, insulin resistance and the development of type 2 diabetes mellitus: the Dallas Heart Study Jessica L. Harding · Meda E. Pavkov · Dianna J. Magliano · Jonathan E. Shaw · Edward W. Gregg · Edward W. Gregg
Innate immune activity as a predictor of persistent insulin secretion and association with responsiveness to CTLA4-Ig treatment in recent-onset type 1 diabetes Ghazaleh Hajmousa · Ewa Przybyt · Frederick Pfister · Genaro A. Paredes-Juarez · Kondaiah Moganti · Stephanie Busch · Jeroen Kuipers · Ingeborg Klaassen · Marja J. A. van Luyn · Guido Krenning · Hans-Peter Hammes · Martin C. Harmsen · Martin C. Harmsen
Hypoglycaemia in type 1 diabetes: technological treatments, their limitations and the place of psychology Mandy Stadion · Kristin Schwerbel · Antonia Graja · Christian Baumeier · Maria Rödiger · Wenke Jonas · Christian Wolfrum · Harald Staiger · Andreas Fritsche · Hans-Ulrich Häring · Nora Klöting · Matthias Blüher · Pamela Fischer-Posovszky · Tim J. Schulz · Hans-Georg Joost · H. Vogel · Annette Schürmann · Annette Schürmann
Amputation-free survival in 17,353 people at high risk for foot ulceration in diabetes: a national observational study John M. Wentworth · John M. Wentworth · John M. Wentworth · Naiara G. Bediaga · Naiara G. Bediaga · Lynne C. Giles · Mario R. Ehlers · Stephen E. Gitelman · Susan Geyer · Carmella Evans-Molina · Leonard C. Harrison · Leonard C. Harrison · Leonard C. Harrison
HbA 1c , diabetes and cognitive decline: the English Longitudinal Study of Ageing David A. Sacks · David A. Sacks · Denice S. Feig · Denice S. Feig · Denice S. Feig
Increased Ifi202b/IFI16 expression stimulates adipogenesis in mice and humans Stefanie Lanzinger · Joachim Rosenbauer · Dorothea Sugiri · Tamara Schikowski · Birgit Treiber · Daniela Klee · Wolfgang Rathmann · Reinhard W. Holl · Reinhard W. Holl
Interplay between genetic predisposition, macronutrient intake and type 2 diabetes incidence: analysis within EPIC-InterAct across eight European countries Jakob Wefers · D. van Moorsel · Jan Hansen · Niels J. Connell · Bas Havekes · Frank A. J. L. Scheer · Joris Hoeks · Nicolaas C. Schaper · Esther Phielix · Matthijs K. C. Hesselink · Patrick Schrauwen · Patrick Schrauwen
Caring for pregnant women whose diabetes antedates pregnancy: is there room for improvement? Krishnarajah Nirantharakumar · Krishnarajah Nirantharakumar · Nuredin Mohammed · Konstantinos A. Toulis · G. Neil Thomas · Parth Narendran · Parth Narendran · Parth Narendran
Impact of long-term air pollution exposure on metabolic control in children and adolescents with type 1 diabetes: results from the DPV registry Aafke W. F. Janssen · Saeed Katiraei · Barbara Bartosinska · Daniel Eberhard · Ko Willems van Dijk · Sander Kersten · Sander Kersten
Clinically meaningful and lasting HbA1c improvement rarely occurs after 5 years of type 1 diabetes: an argument for early, targeted and aggressive intervention following diagnosis Jacqueline M. Ratter · Jacqueline M. Ratter · H.M.M. Rooijackers · Cor W. M. Jacobs · Bastiaan E. de Galan · Cees J. Tack · Rinke Stienstra · Rinke Stienstra · Rinke Stienstra
Absence of cannabinoid 1 receptor in beta cells protects against high-fat/high-sugar diet-induced beta cell dysfunction and inflammation in murine islets Line Hjort · Line Hjort · Regan Vryer · Louise Groth Grunnet · David Burgner · David Burgner · Sjurdur F. Olsen · Sjurdur F. Olsen · Richard Saffery · Allan Vaag · Allan Vaag
Loss of angiopoietin-like 4 (ANGPTL4) in mice with diet-induced obesity uncouples visceral obesity from glucose intolerance partly via the gut microbiota Joseph Proietto · Jaret Malloy · Dongliang Zhuang · Mark Arya · Neale Cohen · Ferdinandus de Looze · Christopher Gilfillan · Paul Griffin · Stephen Hall · Thomas Nathow · Geoffrey S. Oldfield · David O’Neal · Adam Roberts · Bronwyn Stuckey · Dennis K. Yue · Kristin Taylor · Dennis Kim · Dennis Kim
Clinical and scientific value in the pursuit of quantification of beta cells in the pancreas by PET imaging Ian J. Neeland · Shruti Singh · Darren K. McGuire · Gloria Lena Vega · Thomas P. Roddy · Thomas P. Roddy · Dermot F. Reilly · Jose Castro-Perez · Julia Kozlitina · Philipp E. Scherer · Philipp E. Scherer
Which is more important for cardiometabolic health: sedentary time, higher intensity physical activity or cardiorespiratory fitness? The Maastricht Study Mathilde Fraty · Gilberto Velho · Elise Gand · Frédéric Fumeron · Frédéric Fumeron · Stéphanie Ragot · Stéphanie Ragot · Philippe Sosner · Kamel Mohammedi · Barnabas Gellen · Pierre-Jean Saulnier · Pierre-Jean Saulnier · Jean-Michel Halimi · David Montaigne · Gregory Ducrocq · Michaela Rehman · Michel Marre · Michel Marre · Ronan Roussel · Ronan Roussel · Samy Hadjadj · Samy Hadjadj · Samy Hadjadj
Telomere length is reduced in 9- to 16-year-old girls exposed to gestational diabetes in utero Pratik Choudhary · Stephanie A. Amiel · Stephanie A. Amiel
Angptl8 antisense oligonucleotide improves adipose lipid metabolism and prevents diet-induced NAFLD and hepatic insulin resistance in rodents Alexander J. Lakhter · Rachel E. Pratt · Rachel E. Moore · Kaitlin K. Doucette · Bernhard Maier · Linda A. DiMeglio · Emily K. Sims · Emily K. Sims
Correction to: Chronomedicine and type 2 diabetes: shining some light on melatonin Tan Lai Zhou · Abraham A. Kroon · Koen D. Reesink · Miranda T. Schram · Annemarie Koster · N. Schaper · P.C. Dagnelie · C.J.H. van der Kallen · S. J. S. Sep · C. D. A. Stehouwer · R.M.A. Henry · R.M.A. Henry
Beta cell extracellular vesicle miR-21-5p cargo is increased in response to inflammatory cytokines and serves as a biomarker of type 1 diabetes Xiaoyi Qi · Yanjing Guo · Yongfeng Song · Chunxiao Yu · Lifang Zhao · Li Fang · Dehuan Kong · Jiajun Zhao · Ling Gao · Ling Gao
Meta-genome-wide association studies identify a locus on chromosome 1 and multiple variants in the MHC region for serum C-peptide in type 1 diabetes Adam Hulman · Adam Hulman · Dorte Vistisen · Charlotte Glümer · Michael Bergman · Daniel R. Witte · Kristine Færch · Kristine Færch
Diabetes in pregnancy: a new decade of challenges ahead Esther Phielix · M. de Ligt · Lena Bilet · T. van de Weijer · V. B. Schrauwen · Mkc Matthijs Hesselink · P. Schrauwen · P. Schrauwen
Follicle-stimulating hormone enhances hepatic gluconeogenesis by GRK2-mediated AMPK hyperphosphorylation at Ser485 in mice Abdelhadi M. Habeb · Sarah Flanagan · Mohamed A. Zulali · Mohamed A. Abdullah · Renata Pomahačová · Veselin Boyadzhiev · Lesby E. Colindres · Guillermo V. Godoy · Thiruvengadam Vasanthi · Ramlah Al Saif · Aria Setoodeh · Amirreza Haghighi · Alireza Haghighi · Yomna Shaalan · Andrew T. Hattersley · Sian Ellard · Elisa De Franco · Elisa De Franco
The impact of maternal gestational weight gain on cardiometabolic risk factors in children Mia J. Smith · Rochelle M. Hinman · Andrew Getahun · Soojin Kim · Thomas A. Packard · John C. Cambier · John C. Cambier
Pharmacogenomics in diabetes: outcomes of thiamine therapy in TRMA syndrome Thomas Laeger · Teresa Castaño-Martinez · Martin W. Werno · Lukasz Japtok · Christian Baumeier · Wenke Jonas · Burkhard Kleuser · Annette Schurmann · Annette Schurmann
Isabel Valverde, 1937–2018 Noel G. Morgan · Sarah J. Richardson · Sarah J. Richardson
Probiotic intervention in infancy is not associated with development of beta cell autoimmunity and type 1 diabetes Lise L. Kurtzhals · Sidse Kjærhus Nørgaard · Anna L. Secher · Vibeke L. Nichum · Helle Ronneby · Ann Tabor · Ann Tabor · H. David McIntyre · H. David McIntyre · Peter Damm · Peter Damm · E. R. Mathiesen · E. R. Mathiesen · E. R. Mathiesen
Biomarkers of diabetic kidney disease Isabel González-Mariscal · Rodrigo A. Montoro · Máire E. Doyle · Qing-Rong Liu · Michael Rouse · Jennifer F. O’Connell · Sara Santa-Cruz Calvo · Susan M. Krzysik-Walker · Soumita Ghosh · Olga D. Carlson · Elin Lehrmann · Yongqing Zhang · Kevin G. Becker · Chee W. Chia · Paritosh Ghosh · Josephine M. Egan · Josephine M. Egan
Immunological biomarkers for the development and progression of type 1 diabetes Claudia H. T. Tam · Ronald C.W. Ma · Lai Yuk Yuen · Risa Ozaki · Albert M. Li · Yong Hou · Michael H.M. Chan · Chung Shun Ho · Xilin Yang · Juliana C.N. Chan · Wing Hung Tam · Wing Hung Tam
Dietary carbohydrates impair the protective effect of protein restriction against diabetes in NZO mice used as a model of type 2 diabetes Andrew C. Forrestel · Susanne U. Miedlich · Michael Yurcheshen · Steven D. Wittlin · Michael T. Sellix · Michael T. Sellix
Regression of albuminuria and its association with incident cardiovascular outcomes and mortality in type 1 diabetes: the FinnDiane Study Casey M. Rebholz · Bing Yu · Zihe Zheng · Patrick Chang · Adrienne Tin · Anna Köttgen · Anna Köttgen · Lynne E. Wagenknecht · Josef Coresh · Eric Boerwinkle · Elizabeth Selvin · Elizabeth Selvin
Dose-dependent effect of smoking on risk of coronary heart disease, heart failure and stroke in individuals with type 1 diabetes Erkki Savilahti · Taina Härkönen · E. Savilahti · Kaarina Kukkonen · Mikael Kuitunen · Mikael Knip · Mikael Knip
Magnesium deficiency prevents high-fat-diet-induced obesity in mice Beatrice C. Lupsa · Silvio E. Inzucchi · Silvio E. Inzucchi
Hypoglycaemia induces recruitment of non-classical monocytes and cytotoxic lymphocyte subsets in type 1 diabetes Toshiaki Ohkuma · Sanne A.E. Peters · Mark Woodward · Mark Woodward · Mark Woodward · Mark Woodward
Efficacy and safety of methionine aminopeptidase 2 inhibition in type 2 diabetes: a randomised, placebo-controlled clinical trial Christoph Wanner · Nikolaus Marx · Nikolaus Marx
Use of SGLT2 inhibitors in type 2 diabetes: weighing the risks and benefits Eseoghene Ifie · Mark A. Russell · Shalinee Dhayal · Pia Leete · Guido Sebastiani · Laura Nigi · Francesco Dotta · Varpu Marjomäki · Decio L. Eizirik · Noel G. Morgan · Sarah J. Richardson · Sarah J. Richardson
A novel dual PPAR-γ agonist/sEH inhibitor treats diabetic complications in a rat model of type 2 diabetes Tetyana Kendzerska · L. King · Lorraine L. Lipscombe · Lorraine L. Lipscombe · Ruth Croxford · Ian Stanaitis · Gillian Hawker · Gillian Hawker · Gillian Hawker
Prognostic impact of the ankle–brachial index on the development of micro- and macrovascular complications in individuals with type 2 diabetes: the Rio de Janeiro Type 2 Diabetes Cohort Study Markus Lundgren · Berglind Jonsdottir · Helena Elding Larsson · Helena Elding Larsson
BTBR ob/ob mouse model of type 2 diabetes exhibits early loss of retinal function and retinal inflammation followed by late vascular changes Emily K. Sims · Carmella Evans-Molina · Sarah A. Tersey · Decio L. Eizirik · Raghavendra G. Mirmira · Raghavendra G. Mirmira
The impact of hip and knee osteoarthritis on the subsequent risk of incident diabetes: a population-based cohort study Annika Rosengren · Jon Edqvist · Naveed Sattar · Stefan Franzén · Martin Adiels · Ann-Marie Svensson · Marcus Lind · Soffia Gudbjörnsdottir · Soffia Gudbjörnsdottir
Effect of screening for type 1 diabetes on early metabolic control: the DiPiS study Rosemary E. McDowell · Peter Barabas · Josy Augustine · Olivier P. Chevallier · Philip McCarron · Mei Chen · J. Graham McGeown · Tim M. Curtis · Tim M. Curtis
Biomarkers of islet beta cell stress and death in type 1 diabetes M Kolibabka · N Dietrich · Thomas Klein · Hans-Peter Hammes · Hans-Peter Hammes
Excess risk of hospitalisation for heart failure among people with type 2 diabetes Silvija Cvitic · Boris Novakovic · Lavinia Gordon · Christine M. Ulz · Magdalena Mühlberger · Francisca Diaz-Perez · Jihoon E. Joo · Vendula Svendova · Michael G. Schimek · Slave Trajanoski · Richard Saffery · Gernot Desoye · Ursula Hiden · Ursula Hiden
Müller glial dysfunction during diabetic retinopathy in rats is reduced by the acrolein-scavenging drug, 2-hydrazino-4,6-dimethylpyrimidine Nanna Lindekilde · Frans Pouwer · Frans Pouwer
Anti-angiogenic effects of the DPP-4 inhibitor linagliptin via inhibition of VEGFR signalling in the mouse model of oxygen-induced retinopathy Ravi Retnakaran · Chang Ye · Caroline K. Kramer · Anthony J.G. Hanley · Philip W. Connelly · Philip W. Connelly · Mathew Sermer · Bernard Zinman · Bernard Zinman
Human fetoplacental arterial and venous endothelial cells are differentially programmed by gestational diabetes mellitus, resulting in cell-specific barrier function changes Geng Zong · Geng Zong · Benjamin Lebwohl · Frank B. Hu · Frank B. Hu · Laura Sampson · Lauren Dougherty · Walter C. Willett · Walter C. Willett · Andrew T. Chan · Andrew T. Chan · Andrew T. Chan · Qi Sun · Qi Sun · Qi Sun
More work is needed to better understand diabetes distress as a predictor of all-cause mortality in type 2 diabetes Naveed Sattar · David Fitchett · Stefan Hantel · Jyothis T. George · Bernard Zinman · Bernard Zinman
Impact of daily incremental change in environmental temperature on beta cell function and the risk of gestational diabetes in pregnant women Wendy A. Davis · Emma J. Hamilton · David G. Bruce · Timothy M. E. Davis · Timothy M. E. Davis
Growth differentiation factor 15 is positively associated with incidence of diabetes mellitus: the Malmö Diet and Cancer–Cardiovascular Cohort Jun Li · Megan S. Rice · Tianyi Huang · Tianyi Huang · Susan E. Hankinson · Susan E. Hankinson · Susan E. Hankinson · Charles V. Clevenger · Frank B. Hu · Frank B. Hu · Shelley S. Tworoger · Shelley S. Tworoger · Shelley S. Tworoger
Gluten intake and risk of type 2 diabetes in three large prospective cohort studies of US men and women Mengju Liu · Jian Peng · Ningwen Tai · James A. Pearson · Changyun Hu · Junhua Guo · Lin Hou · Hongyu Zhao · F. Susan Wong · Li Wen · Li Wen
Empagliflozin is associated with improvements in liver enzymes potentially consistent with reductions in liver fat: results from randomised trials including the EMPA-REG OUTCOME® trial Kimberly J. Nahon · Fleur Doornink · Maaike E. Straat · Kani Botani · Borja Martínez-Téllez · Gustavo Abreu-Vieira · Jan B. van Klinken · Gardi J. Voortman · Edith C. H. Friesema · Jonatan R. Ruiz · Floris H. P. van Velden · Lioe-Fee de Geus-Oei · Frits Smit · Lenka M. Pereira Arias-Bouda · Jimmy F.P. Berbée · Ingrid M. Jazet · Mariëtte R. Boon · Patrick C. N. Rensen · Patrick C. N. Rensen
Promises and pitfalls of electronic health record analysis Hanna Viskari · Sami Oikarinen · Sanna Hoppu · Tytti Vuorinen · Tytti Vuorinen · Heini Huhtala · Jorma Toppari · Jorma Toppari · Riitta Veijola · Jorma Ilonen · Mikael Knip · Heikki Hyöty · Heikki Hyöty
SGLT2 inhibitors and mechanisms of cardiovascular benefit: a state-of-the-art review Vivian K. Lee · Brett M. Hosking · Joanna Holeniewska · Ewa C. Kubala · Peter Lundh von Leithner · Peter J. Gardner · Richard H. Foxton · David T. Shima · David T. Shima
Non-albuminuric renal impairment is a strong predictor of mortality in individuals with type 2 diabetes: the Renal Insufficiency And Cardiovascular Events (RIACE) Italian multicentre study Abdul H. Khan · Lauren L. Kolb · Melissa Skibba · Markus Hartmann · René Blöcher · Ewgenij Proschak · John D. Imig · John D. Imig
MANF protects human pancreatic beta cells against stress-induced cell death Lindsey M. Berends · Laura Dearden · Yi Chun L. Tung · Peter J. Voshol · Denise S. Fernandez-Twinn · Susan E. Ozanne · Susan E. Ozanne
Sex differences in the association between diabetes and cancer: a systematic review and meta-analysis of 121 cohorts including 20 million individuals and one million events Anitha Pitchika · Manja Jolink · Christiane Winkler · Sandra Hummel · Nadine Hummel · Jan Krumsiek · Gabi Kastenmüller · Jennifer Raab · Olga Kordonouri · Anette-Gabriele Ziegler · Andreas Beyerlein · Andreas Beyerlein
SGLT2 inhibitors: the future for treatment of type 2 diabetes mellitus and other chronic diseases Merlin C. Thomas · David Z.I. Cherney · David Z.I. Cherney
Unexpected subcellular distribution of a specific isoform of the Coxsackie and adenovirus receptor, CAR-SIV, in human pancreatic beta cells Sally M. Marshall · Sally M. Marshall
Associations of maternal type 1 diabetes with childhood adiposity and metabolic health in the offspring: a prospective cohort study Elina Hakonen · Elina Hakonen · Vikash Chandra · Christopher L. Fogarty · Nancy Y. Yu · Jarkko Ustinov · Shintaro Katayama · Emilia Galli · Tatiana Danilova · Päivi Lindholm · Aki Vartiainen · Elisabet Einarsdottir · Kaarel Krjutškov · Juha Kere · Mart Saarma · Maria Lindahl · Timo Otonkoski · Timo Otonkoski · Timo Otonkoski
The actions of SGLT2 inhibitors on metabolism, renal function and blood pressure Timo Rieg · Volker Vallon · Volker Vallon
The bark giving diabetes therapy some bite: the SGLT inhibitors Chiara Ghezzi · Donald D. F. Loo · Ernest M. Wright · Ernest M. Wright
Development of SGLT1 and SGLT2 inhibitors Andrew T. Templin · Daniel T. Meier · Joshua R. Willard · Tami Wolden-Hanson · Kelly Conway · Yin-Guo Lin · Patrick J. Gillespie · Krister Bokvist · Giorgio Attardo · Steven E. Kahn · Donalyn Scheuner · Rebecca L. Hull · Rebecca L. Hull
Antagonising Wnt/β-catenin signalling ameliorates lens-capsulotomy-induced retinal degeneration in a mouse model of diabetes Subodh Verma · John J.V. McMurray · John J.V. McMurray
Physiology of renal glucose handling via SGLT1, SGLT2 and GLUT2 Vikas Bansal · Bernhard O. Boehm · Bernhard O. Boehm · Bernhard O. Boehm · Ariel Darvasi · Ariel Darvasi
Programming of central and peripheral insulin resistance by low birthweight and postnatal catch-up growth in male mice Rory J. McCrimmon · Robert R. Henry · Robert R. Henry
Use of the PET ligand florbetapir for in vivo imaging of pancreatic islet amyloid deposits in h IAPP transgenic mice Manabu Kondo · Katsuya Tanabe · Kikuko Amo-Shiinoki · Masayuki Hatanaka · Tsukasa Morii · Harumi Takahashi · Susumu Seino · Yuichiro Yamada · Yukio Tanizawa · Yukio Tanizawa
Identification of a missense variant in the WFS1 gene that causes a mild form of Wolfram syndrome and is associated with risk for type 2 diabetes in Ashkenazi Jewish individuals Jose R. Hombrebueno · Imran Ali · Jian Xing Ma · Mei Chen · Heping Xu · Heping Xu
SGLT inhibitor adjunct therapy in type 1 diabetes Giuseppe Penno · Anna Solini · Emanuela Orsi · Enzo Bonora · Cecilia Fondelli · Roberto Trevisan · Monica Vedovato · Franco Cavalot · Marco Scardapane · Antonio Nicolucci · Giuseppe Pugliese · Giuseppe Pugliese
FAM13A and POM121C are candidate genes for fasting insulin: functional follow-up analysis of a genome-wide association study Delnaz Roshandel · Rose Gubitosi-Klug · Shelley B. Bull · Shelley B. Bull · Angelo J. Canty · Marcus G. Pezzolesi · George L. King · George L. King · Hillary A. Keenan · Hillary A. Keenan · Janet K. Snell-Bergeon · David M. Maahs · David M. Maahs · Ronald Klein · Barbara E. K. Klein · Trevor J. Orchard · Tina Costacou · Michael N. Weedon · Dcct · Richard A. Oram · Andrew D. Paterson · Andrew D. Paterson
Can insulin response patterns predict metabolic disease risk in individuals with normal glucose tolerance? Reply to Crofts CAP, Brookler K, Henderson G [letter] Helen M. Colhoun · M. Loredana Marcovecchio · M. Loredana Marcovecchio
The impact of restricted gestational weight gain by dietary intervention on fetal growth in women with gestational diabetes mellitus Chi Ho Lee · Chloe Y.Y. Cheung · Yu-Cho Woo · David T.W. Lui · Michele M A Yuen · Carol H.Y. Fong · Ws Chow · Amin Xu · Karen S.L. Lam · Karen S.L. Lam
Management of hyperglycaemia in type 2 diabetes, 2018. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) Daniela Guarino · Diego Moriconi · Andrea Mari · Eleni Rebelos · Daria Colligiani · Simona Baldi · Marco Anselmino · Ele Ferrannini · Monica Nannipieri · Monica Nannipieri
IFN-α induces a preferential long-lasting expression of MHC class I in human pancreatic beta cells Christophe O. Soulage · Laura Sardón Puig · Laurent Soulère · Bader Zarrouki · Michel Guichardant · Michel Lagarde · Nicolas J. Pillon · Nicolas J. Pillon
A contemporary Australian cardiovascular risk equation for type 2 diabetes: the Fremantle Diabetes Study Phase II Laura Formentini · Alexander J. Ryan · Manuel Gálvez-Santisteban · Leslie Carter · Pam R. Taub · John D. Lapek · David J. Gonzalez · Francisco Villarreal · Theodore P. Ciaraldi · José M. Cuezva · Robert R. Henry · Robert R. Henry
Serum kidney injury molecule 1 and β2-microglobulin perform as well as larger biomarker panels for prediction of rapid decline in renal function in type 2 diabetes Kaiyven A. Leslie · Mark A. Russell · Kazuto Taniguchi · Sarah J. Richardson · Noel G. Morgan · Noel G. Morgan
Hyperglycaemia is associated with cancer-related but not non-cancer-related deaths: evidence from the IPC cohort Xiaoyu He · Qiaohong Lai · Cai Chen · Na Li · Fei Sun · Wenting Huang · Shu Zhang · Qilin Yu · Ping Yang · Fei Xiong · Zhishui Chen · Quan Gong · Boxu Ren · Jianping Weng · Decio L. Eizirik · Zhiguang Zhou · Cong-Yi Wang · Cong-Yi Wang
Haemoglobin glycation index and risk for diabetes-related complications in the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation (ADVANCE) trial Sharon T. Mackin · Scott M. Nelson · Joannes J. Kerssens · Rachael Wood · Sarah H. Wild · Helen M. Colhoun · Graham P. Leese · Sam Philip · Robert S. Lindsay · Robert S. Lindsay
Skeletal muscle insulin resistance is induced by 4-hydroxy-2-hexenal, a by-product of n-3 fatty acid peroxidation P K Luukkonen · S Sadevirta · M Umpleby · Aila Rissanen · R Haijula · Helena Gylling · Susanna Lallukka · Antti Hakkarainen · Nina Lundbom · Leanne Hodson · Hannele Yki-Järvinen · Hannele Yki-Järvinen
Both conditional ablation and overexpression of E2 SUMO-conjugating enzyme (UBC9) in mouse pancreatic beta cells result in impaired beta cell function Lily Boutens · Guido Hooiveld · Sourabh Dhingra · Robert A. Cramer · Mihai G. Netea · Rinke Stienstra · Rinke Stienstra
Postprandial hypoglycaemia after Roux-en-Y gastric bypass in individuals with type 2 diabetes Julio Sevillano · María G. Sánchez-Alonso · Begoña Zapatería · María Calderón · Martín Alcalá · María Limones · Jimena Pita · Esther Gramage · Marta Vicente-Rodríguez · Daniel Horrillo · G. Medina-Gomez · María Jesús Obregón · Marta Viana · Ismael Valladolid-Acebes · Gonzalo Herradón · María del Pilar Ramos-Álvarez · María del Pilar Ramos-Álvarez
Genome-wide profiling of histone H3K27 acetylation featured fatty acid signalling in pancreatic beta cells in diet-induced obesity in mice Wendy A. Davis · M. Hunter · Timothy M. E. Davis · Timothy M. E. Davis
Diabetes and pregnancy: national trends over a 15 year period M. Fütterer · N.F. Chhabra · Martin Irmler · J. Beckers · Gerhard K. H. Przemeck · M. Hrabé de Angelis · M. Hrabé de Angelis
Trajectories of childhood BMI and adult diabetes: the Bogalusa Heart Study I. Johansson · Ulf Dahlström · Magnus Edner · Per Näsman · Lars Rydén · Anna Norhammar · Anna Norhammar
Unique metabolic activation of adipose tissue macrophages in obesity promotes inflammatory responses Lucia Berti · B. Raedle · Hans-Ulrich Häring · M. Hrabé de Angelis · Harald Staiger · Harald Staiger
A post-translational balancing act: the good and the bad of SUMOylation in pancreatic islets Giovanni Ometto · Phil Assheton · Francesco Calivá · Piotr Chudzik · Bashir Al-Diri · Andrew Hunter · Toke Bek · Toke Bek
Extracellular matrix molecules and their potential contribution to the function of transplanted pancreatic islets Sigrid C. van Steen · Mark Woodward · John Chalmers · Qiang Li · Michel Marre · Mark E. Cooper · Pavel Hamet · Giuseppe Mancia · Stephen Colagiuri · Bryan Williams · Diederick E. Grobbee · J. Hans DeVries · J. Hans DeVries
Retraction Note to: L-glutamine supplementation induces insulin resistance in adipose tissue and improves insulin signalling in liver and muscle of rats with diet-induced obesity (Diabetologia, (2017), 10.1007/s00125-007-0723-z) Jean-Marc Simon · Frédérique Thomas · Sébastien Czernichow · Olivier Hanon · Cédric Lemogne · Tabassome Simon · Bruno Pannier · Nicolas Danchin · Nicolas Danchin
A cost analysis of intensified vs conventional multifactorial therapy in individuals with type 2 diabetes: a post hoc analysis of the Steno-2 study Melanie J. Davies · Melanie J. Davies · David A. D’Alessio · Judith E. Fradkin · Walter N. Kernan · Chantal Mathieu · Geltrude Mingrone · Geltrude Mingrone · Peter Rossing · Peter Rossing · Apostolos Tsapas · Deborah J. Wexler · John B. Buse · John B. Buse
Live attenuated enterovirus vaccine (OPV) is not associated with islet autoimmunity in children with genetic susceptibility to type 1 diabetes: prospective cohort study Leanne Hodson · C Pramfalk · M Pavlides · C McNeil · Fredrik Karpe · Fredrik Karpe
Adapting to insulin resistance in obesity: role of insulin secretion and clearance Louise A. Donnelly · Kaixin Zhou · Alex S. F. Doney · Christopher Jennison · Paul W. Franks · Ewan R. Pearson · Ewan R. Pearson
Hope vs hype: where are we in type 1 diabetes? Douwe J. Mulder · S. A. De Boer · E. S. Hoekstra · Riemer H. J. A. Slart · Joop D. Lefrandt · Wayel H. Abdulahad · H. J. Lambers Heerspink · Johanna Westra · Johanna Westra
Social deprivation modifies the association between incident foot ulceration and mortality in type 1 and type 2 diabetes: a longitudinal study of a primary-care cohort Per Oskarsson · Ramiro Antuna · P. Geelhoed-Duijvestijn · Jens Krӧger · Raimund Weitgasser · Jan Bolinder · Jan Bolinder
Non-traditional biomarkers and incident diabetes in the Diabetes Prevention Program: comparative effects of lifestyle and metformin interventions Patrick M. Catalano · Patrick M. Catalano
Disruption of beta cell acetyl-CoA carboxylase-1 in mice impairs insulin secretion and beta cell mass Tao Zhang · Jie Xu · Shengxu Li · Lydia A. Bazzano · Jiang He · Paul K. Whelton · Wei Chen · Wei Chen
Genome-wide association study of coronary artery disease among individuals with diabetes: the UK Biobank Xue Bao · Yan Borné · Iram Faqir Muhammad · Jan Nilsson · Lars Lind · Olle Melander · Kaijun Niu · Marju Orho-Melander · Gunnar Engström · Gunnar Engström
Evidence of a liver-alpha cell axis in humans: hepatic insulin resistance attenuates relationship between fasting plasma glucagon and glucagonotropic amino acids Alexandra Coomans De Brachene · Reinaldo Sousa Dos Santos · Laura Marroquí · Maikel L Colli · Lorella Marselli · Raghavendra Rg Mirmira · Piero Marchetti · Decio L. Eizirik · Decio L. Eizirik
Pleiotrophin deletion alters glucose homeostasis, energy metabolism and brown fat thermogenic function in mice James Cantley · Aimee Davenport · Laurène Vetterli · Nandor J. Nemes · P. Tess Whitworth · Ebru Boslem · Le May Thai · Natalie A. Mellett · Peter J. Meikle · Kyle L. Hoehn · David E. James · Trevor J. Biden · Trevor J. Biden
Impact of flash glucose monitoring on hypoglycaemia in adults with type 1 diabetes managed with multiple daily injection therapy: a pre-specified subgroup analysis of the IMPACT randomised controlled trial L Najmi · S Althari · L Gundersen · R Rice · M McCarthy · A Gloyn · P Njolstad · A Majithia · A Majithia
Correction to: Mitochondrial H+-ATP synthase in human skeletal muscle: contribution to dyslipidaemia and insulin resistance Tove Fall · Stefan Gustafsson · Marju Orho-Melander · Erik Ingelsson · Erik Ingelsson
Association of NEFA composition with insulin sensitivity and beta cell function in the Prospective Metabolism and Islet Cell Evaluation (PROMISE) cohort Maria Angela Guzzardi · Leanne Hodson · Letizia Guiducci · F La Rosa · S. Burchielli · Pa Salvadori · Pa Salvadori
The transcription factor STAT6 plays a critical role in promoting beta cell viability and is depleted in islets of individuals with type 1 diabetes Phuoc My Nguyen · Beichen Xie · Olof Idevall-Hagren · Olof Idevall-Hagren
Arctic berry extracts target the gut–liver axis to alleviate metabolic endotoxaemia, insulin resistance and hepatic steatosis in diet-induced obese mice Nicolai J. Wewer Albrechtsen · Kristine Færch · Troels M. Jensen · Daniel R. Witte · Jens Pedersen · Yuvaraj Mahendran · Anna Jonsson · Katrine D. Galsgaard · Marie Winther-Sørensen · Signe S. Torekov · Torsten Lauritzen · Oluf Pedersen · Filip K. Knop · Torben Hansen · Marit E. Jørgensen · Dorte Vistisen · Jens J. Holst · Jens J. Holst
Detection and quantification of beta cells by PET imaging: why clinical implementation has never been closer Marco Colombo · Helen C. Looker · Bassam Farran · Sibylle Hess · Leif Groop · Colin N. A. Palmer · Mary Julia Brosnan · R. Neil Dalton · Max Wong · Charles Turner · Emma Ahlqvist · David B. Dunger · Felix Agakov · Paul N. Durrington · Shona Livingstone · John Betteridge · Paul McKeigue · Helen M. Colhoun · Helen M. Colhoun
Toll-like receptor 9 negatively regulates pancreatic islet beta cell growth and function in a mouse model of type 1 diabetes Thenmalar Vadiveloo · William Jeffcoate · Peter T. Donnan · Helen C. Colhoun · Stuart McGurnaghan · Sarah H. Wild · Rory J. McCrimmon · Graham P. Leese · Graham P. Leese
Mouse pancreatic islet macrophages use locally released ATP to monitor beta cell activity N.F. Chhabra · Moya Wu · M. Fuetterer · Martin Irmler · J. Beckers · M. Goetz · Jan Rozman · Gerhard K. H. Przemeck · M. Hrabé de Angelis · M. Hrabé de Angelis
Differential expression of Lp-PLA2 in obesity and type 2 diabetes and the influence of lipids Stephanie Bien · James S. Pankow · Jeff Haessler · Yinchang Lu · Nathan Pankratz · Rebecca R. Rohde · Alfred Tamuno · Christopher S. Carlson · Fredrick R. Schumacher · Petra Bůžková · Martha L. Daviglus · Unhee Lim · Myriam Fornage · Lindsay Fernández-Rhodes · Larissa Aviles-Santa · Steven Buyske · Myron D. Gross · Mariaelisa Graff · Carmen R. Isasi · Lewis H. Kuller · JoAnn E. Manson · Tara C. Matise · Ross L. Prentice · Lynne R. Wilkens · Sachiko Yoneyama · Ruth J. F. Loos · Ruth J. F. Loos · Lucia A. Hindorff · Loic Le Marchand · Kari E. North · Christopher A. Haiman · Ulrike Peters · Charles Kooperberg · Charles Kooperberg
Galectin-3 is independently associated with progression of nephropathy in type 2 diabetes mellitus Ben Jones · T Buenaventura · B Owen · Jr Cir. · P Johnson · D Bosco · Stephen R. Bloom · Guy A. Rutter · Alejandra Tomas · Alejandra Tomas
Fifty years of pancreatic islet pathology in human type 1 diabetes – insights gained and progress made M Verma · N Y Loh · M Todorcevic · Katherine E. Pinnick · A V Dam · Matt Neville · Fredrik Karpe · Constantinos Christodoulides · Constantinos Christodoulides
Blood pressure targets in type 2 diabetes. Evidence against or in favour of an aggressive approach Veroniqa Lundbäck · Agné Kulyté · Rona J. Strawbridge · Mikael Rydén · Peter Arner · Claude Marcus · Ingrid Dahlman · Ingrid Dahlman
Impact of type 1 diabetes on maternal long-term risk of hospitalisation and mortality: a nationwide combined clinical and register-based cohort study (The EPICOM study) Daniel F. Vatner · Leigh Goedeke · João-Paulo G. Camporez · Kun Lyu · Ali R. Nasiri · Dongyan Zhang · Sanjay Bhanot · Susan F. Murray · Christopher D. Still · Glenn S. Gerhard · Gerald I. Shulman · Varman T. Samuel · Varman T. Samuel
Silencing of high-affinity insulin-reactive B lymphocytes by anergy and impact of the NOD genetic background in mice Ursula A. White · Eric Ravussin · Eric Ravussin
Impact of age at diagnosis and duration of type 2 diabetes on mortality in Australia 1997–2011 Kathryn C.B. Tan · Ching-Lung Cheung · Alan C. H. Lee · Joanne K. Y. Lam · Ying Wong · Sammy W. M. Shiu · Sammy W. M. Shiu
Plasma metabolites associated with type 2 diabetes in a Swedish population : a case-control study nested in a prospective cohort Giuseppe Mancia · Guido Grassi · Guido Grassi
Aberrant intestinal microbiota in individuals with prediabetes Lin Shi · Carl Brunius · Marko Lehtonen · Seppo Auriola · Ingvar A. Bergdahl · Olov Rolandsson · Kati Hanhineva · Rikard Landberg · Rikard Landberg · Rikard Landberg · Rikard Landberg
Prospective associations of circulating adipocyte fatty acid-binding protein levels with risks of renal outcomes and mortality in type 2 diabetes W. Li · Miranda T. Schram · Ttjm Tos Berendschot · Johannes Schouten · Abraham A. Kroon · C.J.H. van der Kallen · Ronald M. A. Henry · Annemarie Koster · P.C. Dagnelie · N. Schaper · Fan Huang · B. ter Haar Romeny · Coen D. A. Stehouwer · A. Houben · A. Houben
The diabetes risk gene TCF7L2 regulates human adipose progenitor cell biology Hiroki Matsuda · Sri Teja Mullapudi · Yu Hsuan Carol Yang · Daniel Hesselson · Didier Y. R. Stainier · Didier Y. R. Stainier
Organ donor pancreases for the study of human islet cell histology and pathophysiology: a precious and valuable resource Melinda T. Coughlan · S. M. Tan · Elif I. Ekinci · M. Snelson · Sally A. Penfold · G. C. Higgins · R. S. Lindblom · Karly C. Sourris · Vicki Thallas-Bonke · George Jerums · A. Skene · David Anthony Power · Richard J. MacIsaac · Mark E. Cooper · Trent M. Woodruff · Trent M. Woodruff
A type 1 diabetes genetic risk score can discriminate monogenic autoimmunity with diabetes from early-onset clustering of polygenic autoimmunity with diabetes Lili Huo · Dianna J. Magliano · Fanny Rancière · Fanny Rancière · Jessica L. Harding · Natalie Nanayakkara · Jonathan E. Shaw · Bendix Carstensen · Bendix Carstensen
Bioelectronic modulation of carotid sinus nerve activity in the rat: a potential therapeutic approach for type 2 diabetes M Occhipinti · F Vistoli · G Amorese · S Del Ghianda · U Boggi · P. Marchetti · P. Marchetti
Prediabetes and diabetes are associated with wider retinal arterioles and venules: the Maastricht study Paul G. Weightman Potter · Julia M. Vlachaki Walker · Josephine L. Robb · John K. Chilton · Ritchie Williamson · Andrew D. Randall · Kate L. J. Ellacott · Craig Beall · Craig Beall
Clinical outcomes of an integrated primary–secondary model of care for individuals with complex type 2 diabetes: a non-inferiority randomised controlled trial Martin Gotthardt · Decio L. Eizirik · Henk-Jan Aanstoot · Olle Korsgren · Dick Mul · Frank Martin · Marti Boss · Tom J. P. Jansen · Sanne A. M. van Lith · Mijke Buitinga · Olof Eriksson · Miriam Cnop · Maarten Brom · Maarten Brom
Human pancreatic neuro-insular network in health and fatty infiltration Kunhua Qin · Ning Zhang · Zhao Zhang · Michael Nipper · Zhenxin Zhu · Jake Leighton · Kexin Xu · Nicolas Musi · Pei Wang · Pei Wang
A new perspective on metformin therapy in type 1 diabetes Brandy M. Heckman-Stoddard · Andrea Decensi · Vikrant V. Sahasrabuddhe · Leslie G. Ford · Leslie G. Ford
Context-dependent memory following recurrent hypoglycaemia in non-diabetic rats is mediated via glucocorticoid signalling in the dorsal hippocampus Kai Sun · Kai Sun · Jiyoung Park · Jiyoung Park · Min Kim · Min Kim · Philipp E. Scherer · Philipp E. Scherer
Metformin: historical overview Khalida Ismail · Calum D. Moulton · Kirsty Winkley · John C. Pickup · Stephen Thomas · Roy Sherwood · Daniel Stahl · Stephanie A. Amiel · Stephanie A. Amiel
Repurposing metformin for the prevention of cancer and cancer recurrence Chinmay S. Marathe · Christopher K. Rayner · Karen L. Jones · Michael Horowitz · Michael Horowitz
The association of depressive symptoms and diabetes distress with glycaemic control and diabetes complications over 2 years in newly diagnosed type 2 diabetes: a prospective cohort study Danielle J. Borg · Ran Wang · Lydia Murray · Hui Tong · Raymond J. Steptoe · Michael A. McGuckin · Sumaira Z. Hasnain · Sumaira Z. Hasnain
Gastrointestinal motility in people with type 1 diabetes and peripheral neuropathy Guanghong Jia · Adam Whaley-Connell · James R. Sowers · James R. Sowers
The effect of interleukin-22 treatment on autoimmune diabetes in the NOD mouse Sally M. Marshall · Sally M. Marshall
60 years of metformin use: a glance at the past and a look to the future Cristina Hernández · Patricia Bogdanov · Cristina Solà-Adell · Joel Sampedro · Marta Valeri · Xavier Genís · Olga Simó-Servat · Marta García-Ramírez · Rafael Simó · Rafael Simó
Screening for neonatal diabetes at day 5 of life using dried blood spot glucose measurement Kayleigh M. van Megen · Matthew P. Spindler · Fleur M. Keij · Ineke Bosch · Fleur Sprangers · Annet van Royen-Kerkhof · Tatjana Nikolic · Bart O. Roep · Bart O. Roep
The mechanisms of action of metformin Felicia Gerst · Robert Wagner · Gabriele Kaiser · Madhura Panse · Martin Heni · Jürgen Machann · Malte N. Bongers · Tina Sartorius · Bence Sipos · Falko Fend · Christian Thiel · Silvio Nadalin · Alfred Königsrainer · Norbert Stefan · Andreas Fritsche · Hans-Ulrich Häring · Susanne Ullrich · Dorothea Siegel-Axel · Dorothea Siegel-Axel
SGLT2 inhibitors and risk of cancer in type 2 diabetes: a systematic review and meta-analysis of randomised controlled trials Laura Formentini · Laura Formentini · Alexander J. Ryan · Alexander J. Ryan · Manuel Gálvez-Santisteban · Leslie Carter · Pam R. Taub · John D. Lapek · David J. Gonzalez · Francisco Villarreal · Theodore P. Ciaraldi · José M. Cuezva · Robert R. Henry · Robert R. Henry
Transplantation sites for porcine islets Caroline M. Hull · Mark Peakman · Timothy Tree · Timothy Tree
Effects of insulin and exercise training on FGF21, its receptors and target genes in obesity and type 2 diabetes Huilin Tang · Huilin Tang · Qi Dai · Weilong Shi · Suodi Zhai · Jiali Han · Jiali Han
Insulitis in human diabetes: a histological evaluation of donor pancreases Ahmed Iqbal · Simon Heller · Simon Heller
Chronic administration of myristic acid improves hyperglycaemia in the Nagoya–Shibata–Yasuda mouse model of congenital type 2 diabetes Ionut Bebu · Barbara H. Braffett · Rodica Pop-Busui · Trevor J. Orchard · David M. Nathan · John M. Lachin · John M. Lachin
Innovative technology shows impact of glycaemic control on peripheral retinal vessels in adolescents with type 1 diabetes Miljan Kuljanin · Gillian I. Bell · Stephen E. Sherman · Stephen E. Sherman · Gilles A. Lajoie · David A. Hess · David A. Hess · David A. Hess
PIWI-interacting RNAs as novel regulators of pancreatic beta cell function Tamae Takato · Kai Iwata · Chiaki Murakami · Yuko Wada · Fumio Sakane · Fumio Sakane
Glucose effectiveness, but not insulin sensitivity, is improved after short-term interval training in individuals with type 2 diabetes mellitus: a controlled, randomised, crossover trial Thomas W. Anderson · Charlotte Granhall · Á. Réthy · Flemming Søndergaard · Mette Thomsen · Mette Thomsen
Immigration to Israel during childhood is associated with diabetes at adolescence: a study of 2.7 million adolescents Xiaoying Yang · Qi Chen · Lihong Sun · Huabing Zhang · Lu Yao · Xiaona Cui · Yong Gao · Fude Fang · Yongsheng Chang · Yongsheng Chang
Salt-inducible kinase 2 and -3 are downregulated in adipose tissue from obese or insulin-resistant individuals : implications for insulin signalling and glucose uptake in human adipocytes T J Key · T J Key
Effect of simultaneous vaccination with H1N1 and GAD-alum on GAD65-induced immune response Adela Brahimaj · Taulant Muka · Maryam Kavousi · Joop S.E. Laven · Abbas Dehghan · Oscar H. Franco · Oscar H. Franco
Conditional islet hypovascularisation does not preclude beta cell expansion during pregnancy in mice Emilie Blond · Emmanuel Disse · Charlotte Cuerq · Jocelyne Drai · Pierre-Jean Valette · M. Laville · Charles Thivolet · Chantal Simon · Cyrielle Caussy · Cyrielle Caussy
The Berlin Declaration: building upon St Vincent Beatriz Tavira · Mikael Chéramy · Stina Axelsson · Linda Åkerman · Johnny Ludvigsson · Rosaura Casas · Rosaura Casas
EASL–EASD–EASO clinical practice guidelines for the management of non-alcoholic fatty liver disease in severely obese people: do they lead to over-referral? Ellis Voerman · Vincent W. V. Jaddoe · Oscar H. Franco · Eric A.P. Steegers · Romy Gaillard · Romy Gaillard
Erratum to: Painting a new picture of personalised medicine for diabetes Francesco Zaccardi · David R. Webb · Melanie J. Davies · Nafeesa N. Dhalwani · Laura J. Gray · Sudesna Chatterjee · Gemma Housley · Dominick Shaw · James W. Hatton · Kamlesh Khunti · Kamlesh Khunti
Precision diabetes: learning from monogenic diabetes Anne-Marie Felton · Sanjay Kalra · Sanjay Kalra
Paracrine GABA and insulin regulate pancreatic alpha cell proliferation in a mouse model of type 1 diabetes Tor Ivar Hansen · Sandra E. Olsen · Elise Cd Haferstrom · Trond Sand · Brian M. Frier · Asta Håberg · Marit R. Bjørgaas · Marit R. Bjørgaas
Perturbations of the anti-ageing hormone Klotho in patients with type 1 diabetes and microalbuminuria Joana F. Sacramento · Maria J. Ribeiro · Tiago B. Rodrigues · Elena Olea · Bernardete F. Melo · Maria P. Guarino · Maria P. Guarino · Rui Fonseca-Pinto · Cristiana R. Ferreira · Joana Coelho · Ana Obeso · Raquel Seiça · Paulo Matafome · Paulo Matafome · Silvia V. Conde · Silvia V. Conde
HMOX1 as a marker of iron excess-induced adipose tissue dysfunction, affecting glucose uptake and respiratory capacity in human adipocytes Emily K. Sims · Alexander J. Lakhter · Emily K. Anderson-Baucum · Tatsuyoshi Kono · Xin Tong · Carmella Evans-Molina · Carmella Evans-Molina
Germinal centre frequency is decreased in pancreatic lymph nodes from individuals with recent-onset type 1 diabetes E.J.M. Feskens · A. Kuijsten · A. Kuijsten
CTRP3 attenuates cardiac dysfunction, inflammation, oxidative stress and cell death in diabetic cardiomyopathy in rats Mark McCarthy · Mark McCarthy
Women with prior gestational diabetes mellitus and prediabetes are characterised by a decreased incretin effect Willem Staels · Willem Staels · Yves Heremans · Gunter Leuckx · Naomi Van Gassen · Ciro Salinno · Sofie De Groef · Martine Cools · Eli Keshet · Yuval Dor · Harry Heimberg · Nico De Leu · Nico De Leu
Functional abolition of carotid body activity restores insulin action and glucose homeostasis in rats: key roles for visceral adipose tissue and the liver Domenico Tricò · Raimund I. Herzog · Raimund I. Herzog
Characterisation of rapid progressors to type 1 diabetes among children with HLA-conferred disease susceptibility Na Xiao · Mengdie Lou · Yi-Tong Lu · Le-Le Yang · Qun Liu · Baolin Liu · Lian-Wen Qi · Ping Li · Ping Li
Ginsenoside Rg5 attenuates hepatic glucagon response via suppression of succinate-associated HIF-1α induction in HFD-fed mice Amélie Bonnefond · Amélie Bonnefond · Philippe Froguel · Philippe Froguel · Philippe Froguel
Association between type 2 diabetes and risk of cancer mortality: a pooled analysis of over 771,000 individuals in the Asia Cohort Consortium Petra M. Pöllänen · Johanna Lempainen · Antti-Pekka Laine · Jorma Toppari · Riitta Veijola · Paula Vähäsalo · Jorma Ilonen · Heli Siljander · Mikael Knip · Mikael Knip
Does training of general practitioners for intensive treatment of people with screen-detected diabetes have a spillover effect on mortality and cardiovascular morbidity in at risk individuals with normoglycaemia? Results from the ADDITION-Denmark cluster-randomised controlled trial Zhen-Guo Ma · Yu-Pei Yuan · Si-Chi Xu · Wen-Ying Wei · Chun-Ru Xu · Xin Zhang · Qing-Qing Wu · Hai-Han Liao · Jian Ni · Qizhu Tang · Qizhu Tang
Predicting hospital stay, mortality and readmission in people admitted for hypoglycaemia: prognostic models derivation and validation Hindrik Mulder · Hindrik Mulder
Precision diabetes: a realistic outlook on a promising approach Jean-Philippe Deglasse · Vinciane El-Hawat · Jean-Christophe Jonas · Jean-Christophe Jonas
The case for too little melatonin signalling in increased diabetes risk Brigitte I. Frohnert · Lisa Ide · Fran Dong · Anna E. Barón · Andrea K. Steck · Jill M. Norris · Marian Rewers · Marian Rewers
Melatonin signalling and type 2 diabetes risk: too little, too much or just right? Sally M. Marshall · Sally M. Marshall
Late-onset islet autoimmunity in childhood: the Diabetes Autoimmunity Study in the Young (DAISY) Elisabeth Kemter · Christian M. Cohrs · Matthias Schäfer · Marion Schuster · Klaus Steinmeyer · Lelia Wolf-van Buerck · Andrea Wolf · A. Wuensch · Mayuko Kurome · Barbara Kessler · Valeri Zakhartchenko · Matthias Loehn · Yuri Ivashchenko · Jochen Seissler · Anke Schulte · Stephan Speier · Eckhard Wolf · Eckhard Wolf
INS-eGFP transgenic pigs: a novel reporter system for studying maturation, growth and vascularisation of neonatal islet-like cell clusters Andrew T. Hattersley · Kashyap Patel · Kashyap Patel
Hedgehog signalling in myeloid cells impacts on body weight, adipose tissue inflammation and glucose metabolism Allen L. Feng · Yun-Yan Xiang · Le Gui · Gesthika Kaltsidis · Qingping Feng · Wei-Yang Lu · Wei-Yang Lu
Peripheral insulin resistance rather than beta cell dysfunction accounts for geographical differences in impaired fasting blood glucose among sub-Saharan African individuals: findings from the RODAM study Thomas Schmidt Voss · Thomas Schmidt Voss · Mikkel Holm Vendelbo · Ulla Kampmann · Steen B. Pedersen · Thomas Alexander Sick Nielsen · Mogens Johannsen · Mads Svart · Mads Svart · Niels Jessen · Niels Jessen · Niels Møller · Niels Møller · Niels Møller
Glucose concentrations of less than 3.0 mmol/l (54 mg/dl) should be reported in clinical trials: a joint position statement of the American Diabetes Association and the Europian Association for the Study of Diabetes Giuseppe Maltese · Nikolaos Fountoulakis · Richard C.M. Siow · Luigi Gnudi · Janaka Karalliedde · Janaka Karalliedde
Iron: how much is too much? Takeru Shima · Takashi Matsui · Takashi Matsui · Subrina Jesmin · Masahiro Okamoto · Masahiro Okamoto · Mariko Soya · Koshiro Inoue · Yu-Fan Liu · Ignacio Torres-Aleman · Bruce S. McEwen · Hideaki Soya · Hideaki Soya
Reciprocal regulation of mTOR complexes in pancreatic islets from humans with type 2 diabetes João Paulo Monteiro Carvalho Mori Cunha · Gunter Leuckx · Peter Sterkendries · Hannelie Korf · Gabriela Bomfim-Ferreira · Lutgart Overbergh · Bart Vaes · Harry Heimberg · Conny Gysemans · Chantal Mathieu · Chantal Mathieu
PCSK9 inhibition: the dawn of a new age in cholesterol lowering? Annie Hasib · Mt Ng · Victor Gault · Dawood Khan · Vadivel Parthsarathy · Peter R. Flatt · Nigel Irwin · Nigel Irwin
Glia: silent partners in energy homeostasis and obesity pathogenesis Ting Yuan · Sahar Rafizadeh · Kanaka Durga Devi Gorrepati · Blaz Lupse · Jose Oberholzer · Kathrin Maedler · Amin Ardestani · Amin Ardestani
Loss of prohormone convertase 2 promotes beta cell dysfunction in a rodent transplant model expressing human pro-islet amyloid polypeptide David Preiss · Marion Mafham · Marion Mafham
The heritable basis of gene–environment interactions in cardiometabolic traits John D. Douglass · Mauricio D. Dorfman · Joshua P. Thaler · Joshua P. Thaler
Associations of maternal BMI and insulin resistance with the maternal metabolome and newborn outcomes Jaques A. Courtade · Evan Y. Wang · Paul Yen · Derek L. Dai · Galina Soukhatcheva · Paul C. Orban · C. Bruce Verchere · C. Bruce Verchere
Assessment of urinary microparticles in normotensive patients with type 1 diabetes Paddy C. Dempsey · Paddy C. Dempsey · Megan S. Grace · Megan S. Grace · Megan S. Grace · David W. Dunstan · David W. Dunstan
APPL1 prevents pancreatic beta cell death and inflammation by dampening NFκB activation in a mouse model of type 1 diabetes Yuliya Lytvyn · Fengxia Xiao · Chris R. J. Kennedy · Bruce A. Perkins · Heather N. Reich · James W. Scholey · David Z.I. Cherney · Dylan Burger · Dylan Burger · Dylan Burger
Moderate exercise ameliorates dysregulated hippocampal glycometabolism and memory function in a rat model of type 2 diabetes Xue Jiang · Yawen Zhou · Kelvin K. L. Wu · Zhanrui Chen · Aimin Xu · Kenneth K.Y. Cheng · Kenneth K.Y. Cheng
SHP-1 activation inhibits vascular smooth muscle cell proliferation and intimal hyperplasia in a rodent model of insulin resistance and diabetes Kristian Karstoft · Margaret A. Clark · Ida Jakobsen · Ida A. Müller · Bente Klarlund Pedersen · Thomas P. J. Solomon · Mathias Ried-Larsen · Mathias Ried-Larsen · Mathias Ried-Larsen
Mitochondria-related transcriptional signature is downregulated in adipocytes in obesity: a study of young healthy MZ twins Hilde Herrema · Richard G. IJzerman · Max Nieuwdorp · Max Nieuwdorp
Discriminatory ability of simple OGTT-based beta cell function indices for prediction of prediabetes and type 2 diabetes: the CODAM study Aidan McElduff · Aidan McElduff
Interrupting prolonged sitting in type 2 diabetes: nocturnal persistence of improved glycaemic control Joshua R. Willard · Breanne M. Barrow · Sakeneh Zraika · Sakeneh Zraika
The TetO rat as a new translational model for type 2 diabetic retinopathy by inducible insulin receptor knockdown Louise J. C. J. den Biggelaar · Simone J. S. Sep · Simone J. P. M. Eussen · Andrea Mari · Ele Ferrannini · Marleen M. J. van Greevenbroek · Carla J.H. van der Kallen · Casper G. Schalkwijk · Coen D. A. Stehouwer · Pieter C. Dagnelie · Pieter C. Dagnelie
GAD vaccine reduces insulin loss in recently diagnosed type 1 diabetes: findings from a Bayesian meta-analysis Leif Groop · Leif Groop
Are the Institute of Medicine weight gain targets applicable in women with gestational diabetes mellitus Nadine Taleb · Ali Emami · Corinne Suppère · Virginie Messier · Laurent Legault · Martin Ladouceur · Jean-Louis Chiasson · Ahmad Haidar · Rémi Rabasa-Lhoret · Rémi Rabasa-Lhoret
Increased fetal adiposity prior to diagnosis of gestational diabetes in South Asians: more evidence for the thin–fat baby Craig A. Beam · Colleen MacCallum · Kevan C. Herold · Diane K. Wherrett · Jerry P. Palmer · Johnny Ludvigsson · Johnny Ludvigsson
Targeted next-generation sequencing reveals MODY in up to 6.5% of antibody-negative diabetes cases listed in the Norwegian Childhood Diabetes Registry Tang Wong · Tang Wong · Tang Wong · Robyn A. Barnes · Robyn A. Barnes · Glynis P. Ross · Glynis P. Ross · N.W. Cheung · N.W. Cheung · Jeff R. Flack · Jeff R. Flack · Jeff R. Flack · Jeff R. Flack
Breaking sitting with light activities vs structured exercise: a randomised crossover study demonstrating benefits for glycaemic control and insulin sensitivity in type 2 diabetes Hema Venkataraman · Uma Ram · Sam Craik · Anuradhai Arungunasekaran · Suresh Seshadri · Ponnusamy Saravanan · Ponnusamy Saravanan · Ponnusamy Saravanan
The cytoskeletal protein septin 11 is associated with human obesity and is involved in adipocyte lipid storage and metabolism Bernard M. F. M. Duvivier · Nicolaas C. Schaper · Matthijs K. C. Hesselink · Linh van Kan · Nathalie Stienen · Bjorn Winkens · Annemarie Koster · Hans Savelberg · Hans Savelberg
The beneficial effects of empagliflozin, an SGLT2 inhibitor, on atherosclerosis in ApoE−/− mice fed a western diet Megan L. Gow · Megan L. Gow · Louise A. Baur · Louise A. Baur · Nathan A. Johnson · Christopher T. Cowell · Christopher T. Cowell
A longitudinal study of iron status during pregnancy and the risk of gestational diabetes: findings from a prospective, multiracial cohort Ji Hye Han · Tae Jung Oh · Ghayoung Lee · Hyo Jin Maeng · Dong Hwa Lee · Kyoung Min Kim · Sung Hee Choi · Hak Chul Jang · Hye Seung Lee · Kyong Soo Park · Young-Bum Kim · Soo Lim · Soo Lim
Human multipotent adult progenitor cells enhance islet function and revascularisation when co-transplanted as a composite pellet in a mouse model of diabetes Giles S. H. Yeo · Giles S. H. Yeo
Genetics of obesity: can an old dog teach us new tricks? Andrew C. Forrestel · Susanne U. Miedlich · Michael Yurcheshen · Steven D. Wittlin · Michael T. Sellix · Michael T. Sellix
Gestational diabetes and adverse perinatal outcomes from 716,152 births in France in 2012 Abby Willcox · Sarah J. Richardson · Lucy S. K. Walker · Sally C. Kent · Noel G. Morgan · Kathleen M. Gillespie · Kathleen M. Gillespie
AICAR ameliorates high-fat diet-associated pathophysiology in mouse and ex vivo models, independent of adiponectin Cécile Billionnet · Delphine Mitanchez · Alain Weill · Jacky Nizard · Jacky Nizard · François Alla · Agnès Hartemann · Sophie Jacqueminet · Sophie Jacqueminet
Genetic evidence of a causal effect of insulin resistance on branched-chain amino acid levels Mark I. McCarthy · Mark I. McCarthy
Combined NOX1/4 inhibition with GKT137831 in mice provides dose-dependent reno- and atheroprotection even in established micro- and macrovascular disease Emma Börgeson · Emma Börgeson · Ville Wallenius · Gulam H. Syed · Catherine Godson · Catherine Godson
Exome-chip association analysis reveals an Asian-specific missense variant in PAX4 associated with type 2 diabetes in Chinese individuals Andrea D. Smith · Andrea D. Smith · Alessio Crippa · James Woodcock · Soren Brage · Soren Brage
Long-term dietary nitrite and nitrate deficiency causes the metabolic syndrome, endothelial dysfunction and cardiovascular death in mice Cristina Zanchi · Daniela Macconi · Piera Trionfini · Susanna Tomasoni · Daniela Rottoli · Monica Locatelli · Michael A. Rudnicki · Jo Vandesompele · Pieter Mestdagh · Giuseppe Remuzzi · Ariela Benigni · Carlamaria Zoja · Carlamaria Zoja
Lifestyle and precision diabetes medicine: will genomics help optimise the prediction, prevention and treatment of type 2 diabetes through lifestyle therapy? Karlijn Meeks · Karien Stronks · Adebowale Adeyemo · Juliet Addo · Silver Bahendeka · Erik Beune · Ellis Owusu-Dabo · Ina Danquah · Cecilia Galbete · Peter Henneman · Kerstin Klipstein-Grobusch · Kerstin Klipstein-Grobusch · Frank P. Mockenhaupt · Kwame Osei · Matthias B. Schulze · Joachim Spranger · Liam Smeeth · Charles Agyemang · Charles Agyemang
Towards a systematic nationwide screening strategy for MODY Mohammed A. Abdelsaid · Maha Coucha · Sherif Hafez · Abdul Yasir · Maribeth H. Johnson · Adviye Ergul · Adviye Ergul
Re-addressing the 2013 consensus guidelines for the diagnosis of insulitis in human type 1 diabetes: is change necessary? Reply to Campbell-Thompson ML, Atkinson MA, Butler AE et al [letter] Paul W. Franks · Paul W. Franks · Paul W. Franks · Alaitz Poveda · Alaitz Poveda
Differential methylation of genes in individuals exposed to maternal diabetes in utero Beverley M. Shields · Kevin Colclough · Kevin Colclough
PCSK9 inhibition and the global diabetes epidemic Marcus Lundberg · Peter Seiron · Sofie Ingvast · Olle Korsgren · Oskar Skog · Oskar Skog
Associations between hepatic miRNA expression, liver triacylglycerols and gut microbiota during metabolic adaptation to high-fat diet in mice Valentine S. Moullé · Kevin Vivot · Caroline Tremblay · Bader Zarrouki · Julien Ghislain · Vincent Poitout · Vincent Poitout
Type 1 diabetic patients with peripheral neuropathy have pan-enteric prolongation of gastrointestinal transit times and an altered caecal pH profile Inne Crèvecoeur · Valborg Gudmundsdottir · Saurabh Vig · Fernanda Marques Câmara Sodré · Wannes D’Hertog · Ana Carolina Fierro · Leentje Van Lommel · Conny Gysemans · Kathleen Marchal · Etienne Waelkens · Frans Schuit · Søren Brunak · Søren Brunak · Lut Overbergh · Chantal Mathieu · Chantal Mathieu
Translating HbA1c measurements into estimated average glucose values in pregnant women with diabetes Adam D. Farmer · Adam D. Farmer · Anne Grave Pedersen · Anne Grave Pedersen · Birgitte Brock · Birgitte Brock · Poul Erik Jakobsen · Jesper Karmisholt · Sahar Mohammed · S. Mark Scott · Asbjørn Mohr Drewes · Christina Brock · Christina Brock · Christina Brock · Christina Brock
Low muscle mass and risk of type 2 diabetes in middle-aged and older adults: findings from the KoGES Graham R. Law · Mark S. Gilthorpe · Anna Secher · Rosemary C. Temple · Rudolf W. Bilous · Elisabeth R. Mathiesen · Helen R. Murphy · Eleanor M. Scott · Eleanor M. Scott
The cardiovascular benefits of empagliflozin: SGLT2-dependent and -independent effects Andrew N. Reynolds · Jim Mann · Sheila Williams · Bernard J. Venn · Bernard J. Venn
Interferon-α mediates human beta cell HLA class I overexpression, endoplasmic reticulum stress and apoptosis, three hallmarks of early human type 1 diabetes Jang Won Son · Seong Su Lee · Sung Rae Kim · Soon Jib Yoo · Bong Yun Cha · Ho Young Son · Nam H. Cho · Nam H. Cho
Re-addressing the 2013 consensus guidelines for the diagnosis of insulitis in human type 1 diabetes: is change necessary? Roberto Vettor · Silvio E. Inzucchi · Paola Fioretto · Paola Fioretto
Season of birth and the risk of type 2 diabetes in adulthood: a prospective cohort study of 0.5 million Chinese adults Bjørn Olav Åsvold · Kristian Midthjell · Steinar Krokstad · Vegar Rangul · Adrian Bauman · Adrian Bauman
Targeted deletion of Traf2 allows immunosuppression-free islet allograft survival in mice Hanna Honkanen · Sami Oikarinen · Noora Nurminen · Olli H. Laitinen · Heini Huhtala · Jussi Lehtonen · Tanja Ruokoranta · Minna M. Hankaniemi · Valerie Lecouturier · Jeffrey Almond · Sisko Tauriainen · Olli Simell · Olli Simell · Jorma Ilonen · Riitta Veijola · Hanna Viskari · Mikael Knip · Heikki Hyöty · Heikki Hyöty
Frequent and intensive physical activity reduces risk of cardiovascular events in type 1 diabetes Jeanette E. Villanueva · Jeanette E. Villanueva · Stacey N. Walters · Mitsuru Saito · Elisabeth K. Malle · Nathan W. Zammit · Katherine A. Watson · Katherine A. Watson · Robert Brink · Nicole L. La Gruta · Nicole L. La Gruta · Stephen I. Alexander · Shane T. Grey · Shane T. Grey
Chronomedicine and type 2 diabetes: shining some light on melatonin Rong Wu · Jian-guang Sun · J. Wang · Binhua Li · Qingsong Liu · Guang Ning · Wanzhu Jin · Zengqiang Yuan · Zengqiang Yuan
Risk of pancreatic diseases by second-line anti diabetes drug class: real world based evidence Julien Vouillarmet · Myriam Moret · Isabelle Morelec · Paul Michon · Julien Dubreuil · Julien Dubreuil
Pancreatic alpha cell-selective deletion of Tcf7l2 impairs glucagon secretion and counter-regulatory responses to hypoglycaemia in mice Lin Xu · Maria Carolina Borges · Gibran Hemani · Debbie A. Lawlor · Debbie A. Lawlor
Improving the clinical value and utility of CGM systems: issues and recommendations Fiona N. Manderson Koivula · Neville H. McClenaghan · Alan Harper · Catriona Kelly · Catriona Kelly
miRNAs transferred by exosomes from T lymphocytes to beta cells contribute to type 1 diabetes development I. M. Atzeni · P. van der Zee · Hendri H. Pas · Gilles Diercks · Andries J. Smit · Andries J. Smit
The sodium-dependent glucose transporters (SGLT) as a new promisingpharmacological target in human ischaemic hearts Piero Marchetti · Mara Suleiman · Lorella Marselli · Lorella Marselli
Targeting the C5a-C5aR1 signalling axis in diabetic kidney disease Matthew B. Johnson · Kashyap Patel · Elisa De Franco · Jayne Houghton · Timothy J. McDonald · Timothy J. McDonald · Sian Ellard · Sarah E. Flanagan · Andrew T. Hattersley · Andrew T. Hattersley
Clustering on baseline clinical variables identifies subgroups of type 2 diabetes patients with different rate of progression over 18 months: a DIRECT study Dinesh Selvarajah · Iain D. Wilkinson · F Fang · A Sankar · Jennifer Davies · Elaine Boland · Rajiv Gandhi · Irene Tracey · Solomon Tesfaye · Solomon Tesfaye
Prolonged exposure of mouse and human podocytes to insulin induces insulin resistance through lysosomal and proteasomal degradation of the insulin receptor Jelena P. Seferovic · Marc A. Pfeffer · Brian Claggett · Akshay S. Desai · Dick de Zeeuw · Steven M. Haffner · John J.V. McMurray · Hans-Henrik Parving · Hans-Henrik Parving · Hans-Henrik Parving · Scott D. Solomon · Nish Chaturvedi · Nish Chaturvedi
Gcg CreERT2 knockin mice as a tool for genetic manipulation in pancreatic alpha cells Nina Lindell · Annelie Carlsson · Ann Josefsson · Ulf Samuelsson · Ulf Samuelsson
Event rates and risk factors for diabetic ketoacidosis in adult type 1 diabetes: analysis from the German/Austrian DPV registry based on 48,067 patients Chiyo Shiota · Krishna Prasadan · Ping Guo · Joseph Fusco · Xiangwei Xiao · George K. Gittes · George K. Gittes
Visceral adipose tissue volume is associated with F-18-FDG-PET assessed arterial inflammation in male patients with early type 2 diabetes Jane West · Jane West · Gillian Santorelli · Peter H. Whincup · Lesley Smith · Naveed Sattar · Noel Cameron · Diane Farrar · Paul J. Collings · John Wright · Debbie A. Lawlor · Debbie A. Lawlor
MicroRNA-184 is a downstream effector of albuminuria driving renal fibrosis in rats with diabetic nephropathy Shazli Azmi · Maryam Ferdousi · Uazman Alam · Uazman Alam · Ioannis N. Petropoulos · Georgios Ponirakis · Georgios Ponirakis · Andrew Marshall · Omar Asghar · Hassan Fadavi · Wendy Jones · Mitra Tavakoli · Mitra Tavakoli · Andrew J.M. Boulton · Maria Jeziorska · Handrean Soran · Nathan Efron · Rayaz A. Malik · Rayaz A. Malik · Rayaz A. Malik
Modelling incremental benefits on macro- and micro-vascular complications rates when targeting lower systolic blood pressure levels in type 2 diabetes John R. Petrie · Anne L. Peters · Richard M. Bergenstal · Reinhard W. Holl · G. Alexander Fleming · Lutz Heinemann · Lutz Heinemann
Low oxidation of branched-chain amino acids in people with type 2 diabetes may underlie increased systemic levels C. Coopmans · R.M.A. Henry · J. Heijman · Annemarie Koster · P.C. Dagnelie · N. Schaper · C.J.H. van der Kallen · R. den Engelsman · H. Crijns · C. D. A. Stehouwer · C. D. A. Stehouwer
Circulating adipokines are associated with pre-eclampsia in women with type 1 diabetes Jrj Inshaw · Jrj Inshaw · Nm Walker · Catriona Elizabeth Wallace · Leonardo Bottolo · Leonardo Bottolo · John A. Todd · John A. Todd · John A. Todd
Lower corneal nerve fibre length identifies diabetic neuropathy in older adults with diabetes: results from the Canadian Study of Longevity in Type 1 Diabetes Naveed Sattar · P Valensi · David Preiss · R Dent · I Bridges · A Ruzza · M Cyrille · Y Handelsman · Y Handelsman
Gestational retinal microvasculature and the risk of 5 year postpartum abnormal glucose metabolism M Godazgar · Margarita V. Chibalina · Quan Zhang · Patrik Rorsman · Patrik Rorsman
Europe has to step up its efforts to produce innovative and safe diabetes technology Ling-Jun Li · Kok Hian Tan · Kok Hian Tan · Izzuddin M. Aris · Yap Seng Chong · Yap Seng Chong · Seang-Mei Saw · Peter D. Gluckman · Jie Jin Wang · Tien Yin Wong · Tien Yin Wong
Localisation of Advanced Glycation End products (AGEs) and fluorescence in skin Raphael Goldacre · Raphael Goldacre
Spatial distribution of early red lesions is a risk factor for development of vision-threatening diabetic retinopathy Andri O. Steinarsson · Soffia Gudbjörnsdottir · Stefan Franzén · Ann-Marie Svensson · Naveed Sattar · Naveed Sattar
Differences in abdominal and femoral adipose tissue oxygen tension contribute to the adipose tissue phenotype in overweight and obese women Thomas R. Pieber · Steven P. Marso · Darren K. McGuire · Bernard Zinman · Neil Poulter · Scott S. Emerson · Richard E. Pratley · Richard E. Pratley · Vincent Woo · Simon Heller · Martin Lange · Kirstine Brown-Frandsen · Alan Moses · Jesper Barner Lekdorf · Lucine Lehmann · Kajsa Kvist · John B. Buse · John B. Buse
What determines treatment satisfaction of type 2 diabetes patients on insulin therapy? An observational study in eight European countries Brandon S. J. Davies · Brandon S. J. Davies
Expression of Concern: Circulating ghrelin concentrations are lowered by intracerebroventricular insulin Christoph Nowak · Axel C. Carlsson · Carl Johan Östgren · Fredrik Nyström · Moudud Alam · Tobias Feldreich · Johan Sundström · Juan-Jesus Carrero · Jerzy Leppert · Pär Hedberg · Egil Henriksen · Antonio Carlos Cordeiro · Vilmantas Giedraitis · Lars Lind · Erik Ingelsson · Tove Fall · Johan Ärnlöv · Johan Ärnlöv
Osteomyelitis of the foot: non-surgical management, SPECT/CT scanning and minimising the duration of antibiotic use Willem Staels · Yannick Verdonck · Yves Heremans · Gunter Leuckx · Sofie De Groef · Carlo Heirman · Eelco J.P. de Koning · Conny Gysemans · Kris Thielemans · Luc Baeyens · Harry Heimberg · Nico De Leu · Nico De Leu
Effects of hepatic glycogen on food intake and glucose homeostasis are mediated by the vagus nerve in mice Louise Brunkwall · Marju Orho-Melander · Marju Orho-Melander
Studies into severe famine in early life and diabetes in adulthood: the need to control for differences in participant age and location Bruno M. Carvalho · Dioze Guadagnini · Daniela Miti Tsukumo · André Almeida Schenka · Paulo Latuf-Filho · José Vassallo · Jailson C. Dias · Lauro T. Kubota · José B.C. Carvalheira · M. J. A. Saad · M. J. A. Saad
Unravelling the regulation of insulin transport across the brain endothelial cell Christoph Kapitza · Kirsten Dahl · Jacob Bonde Jacobsen · Mads Buhl Axelsen · Anne Flint · Anne Flint
The human serum protein C4b-binding protein inhibits pancreatic IAPP-induced inflammasome activation Chihua Li · L. H. Lumey · L. H. Lumey
Metformin prevents ischaemic ventricular fibrillation in metabolically normal pigs Klaudia Kulak · Gunilla T. Westermark · Nikolina Papac-Milicevic · Erik Renström · Anna M. Blom · Ben C. King · Ben C. King
Bed rest and resistive vibration exercise unveil novel links between skeletal muscle mitochondrial function and insulin resistance John Wilding · John Wilding
Effect of screening for type 2 diabetes on risk of cardiovascular disease and mortality: a controlled trial among 139,075 individuals diagnosed with diabetes in Denmark between 2001 and 2009 Jessica C. Kiefte-de Jong · Jessica C. Kiefte-de Jong · Jessica C. Kiefte-de Jong · Yanping Li · Mu Chen · Gary C. Curhan · Josiemer Mattei · Vasanti S. Malik · John P. Forman · Oscar H. Franco · Frank B. Hu · Frank B. Hu · Frank B. Hu
Association of serum microRNAs with islet autoimmunity, disease progression and metabolic impairment in relatives at risk of type 1 diabetes Helena Kenny · Floriane Rudwill · Laura Breen · Michele Salanova · Dieter Blottner · Tim Heise · Martina Heer · Stéphane Blanc · Donal J. O’Gorman · Donal J. O’Gorman
SGLT2 inhibitors and diabetic ketoacidosis: data from the FDA Adverse Event Reporting System Amalia Gastaldelli · M. Gaggini · Chiara Rosso · V. Della Latta · Milena Marietti · G. Caviglia · F. Carli · E. Buzzigoli · Demetrio Ciociaro · M.L. Abate · A. Smedile · G.M. Saracco · Elisabetta Bugianesi · Elisabetta Bugianesi
In vivo measurement and biological characterisation of the diabetes-associated mutant insulin p.R46Q (GlnB22-insulin) Isaac Snowhite · Gloria Allende · Jay M. Sosenko · Ricardo L. Pastori · Shari Messinger Cayetano · Alberto Pugliese · Alberto Pugliese
Fatty acid status in infancy is associated with the risk of type 1 diabetes-associated autoimmunity Julie Støy · Jørgen Olsen · Soo-Young Park · Søren Gregersen · Claudia U. Hjørringgaard · Graeme I. Bell · Graeme I. Bell
Retinopathy with central oedema in an INS C94Y transgenic pig model of long-term diabetes Raffaella Mastrocola · Debora Nigro · As Cento · G Schiano · Fausto Chiazza · F. Dal Bello · Francesco Romaniello · Massimo Collino · Claudio Medana · Manuela Aragno · Manuela Aragno
Alcohol drinking patterns and risk of diabetes: a cohort study of 70,551 men and women from the general Danish population Rebecca Stokes · Rebecca Stokes · Kim Cheng · Amit Lalwani · Amit Lalwani · Michael M. Swarbrick · Helen E. Thomas · Thomas Loudovaris · Thomas W. H. Kay · Wayne J. Hawthorne · Philip J. O’Connell · Jenny E. Gunton · Jenny E. Gunton
Serum adiponectin predicts fracture risk in individuals with type 2 diabetes: the Fukuoka Diabetes Registry Aleksandar Ivovic · Andrei I. Oprescu · Khajag Koulajian · Yusaku Mori · Judith A. Eversley · Liling Zhang · Rodolfo Nino-Fong · Gary F. Lewis · Marc Y. Donath · Michael Karin · Michael B. Wheeler · Jan A. Ehses · Jan A. Ehses · Allen Volchuk · Catherine B. Chan · Adria Giacca · Adria Giacca
GLP-1/glucagon receptor co-agonism for treatment of obesity Charlotte Holst · Ulrik Becker · Ulrik Becker · Marit E. Jørgensen · Marit E. Jørgensen · Morten Grønbæk · Janne Schurmann Tolstrup · Janne Schurmann Tolstrup
Vascular complications in diabetes: old messages, new thoughts Yuji Komorita · Masanori Iwase · Hiroki Fujii · Toshiaki Ohkuma · Toshiaki Ohkuma · Hitoshi Ide · Hitoshi Ide · Tamaki Jodai-Kitamura · Akiko Sumi · Masahito Yoshinari · Udai Nakamura · Dongchon Kang · Takanari Kitazono · Takanari Kitazono
Peptide serum markers in islet autoantibody-positive children Miguel A. Sánchez-Garrido · Sara J. Brandt · Christoffer Clemmensen · Timo D. Müller · Richard D. DiMarchi · Matthias H. Tschöp · Matthias H. Tschöp
Liver triacylglycerol content and gestational diabetes: effects of moderate energy restriction Josephine M. Forbes · A. K. Fotheringham · A. K. Fotheringham
Normoalbuminuric chronic kidney disease in type 1 diabetes: is it real and is it serious? Christine von Toerne · Michael Laimighofer · Peter Achenbach · Andreas Beyerlein · Tonia de las Heras Gala · Jan Krumsiek · Fabian J. Theis · Anette-G. Ziegler · Stefanie M. Hauck · Stefanie M. Hauck
Autoantibody binding in liquid phase to IL-2 in human sera is not type 1 diabetes specific Kenneth Hodson · Kenneth Hodson · Chiara Dalla Man · Fiona E. Smith · Alison C. Barnes · Catherine McParlin · Catherine McParlin · Claudio Cobelli · Stephen C. Robson · Stephen C. Robson · Vera Araujo-Soares · Roy Taylor · Roy Taylor · Roy Taylor
ERK1 is dispensable for mouse pancreatic beta cell function but is necessary for glucose-induced full activation of MSK1 and CREB V. Rigalleau · Laurence Blanco · Laure Alexandre · Emilie Pupier · Catherine Lasseur · Nicole Barthe · Christian Combe · Christian Combe
Age at natural menopause and risk of type 2 diabetes: a prospective cohort study Ilaria Marzinotto · Daniela Liberati · Cristina Brigatti · Riccardo Bonfanti · Angela Stabilini · Paolo Monti · Emanuele Bosi · Lorenzo Piemonti · Vito Lampasona · Vito Lampasona
Pharmacogenetics in type 2 diabetes: precision medicine or discovery tool? Claudia R.L. Cardoso · Juliana Valéria de Melo · Guilherme C. Salles · Nathalie C. Leite · Gil F. Salles · Gil F. Salles
Independent associations between a metabolic syndrome severity score and future diabetes by sex and race: the Atherosclerosis Risk In Communities Study and Jackson Heart Study Beata Lecka-Czernik · Beata Lecka-Czernik
Patterns of cutaneous nerve fibre loss and regeneration in type 2 diabetes with painful and painless polyneuropathy Sarah H. Koning · Jelmer J. van Zanden · Klaas Hoogenberg · Helen L. Lutgers · Alberdina W. Klomp · Fleurisca J. Korteweg · Aren J. van Loon · Bruce H. R. Wolffenbuttel · Paul P. van den Berg · Paul P. van den Berg
Serum dehydroepiandrosterone levels are associated with lower risk of type 2 diabetes: the Rotterdam Study Mika Kina-Tanada · Mayuko Sakanashi · Akihide Tanimoto · Tadashi Kaname · Toshihiro Matsuzaki · Katsuhiko Noguchi · Taro Uchida · Junko Nakasone · Chisayo Kozuka · Masayoshi Ishida · Haruaki Kubota · Yuji Taira · Yuichi Totsuka · Shinichiro Kina · Hajime Sunakawa · Junichi Omura · Kimio Satoh · Hiroaki Shimokawa · Nobuyuki Yanagihara · Shiro Maeda · Yusuke Ohya · Masayuki Matsushita · Hiroaki Masuzaki · Akira Arasaki · Masato Tsutsui · Masato Tsutsui
MicroRNA 21 targets BCL2 mRNA to increase apoptosis in rat and human beta cells Rebecca K. Simmons · Rebecca K. Simmons · Niels Henrik Bruun · Daniel R. Witte · Knut Borch-Johnsen · Marit E. Jørgensen · Marit E. Jørgensen · Annelli Sandbæk · Torsten Lauritzen · Torsten Lauritzen
Metabolic brain adaptations to recurrent hypoglycaemia may explain the link between type 1 diabetes mellitus and epilepsy and point towards future study and treatment options Julia Braune · Ulrike Weyer · Madlen Matz-Soja · Constance Hobusch · Matthias Kern · Anne Kunath · Nora Klöting · Susann Kralisch · Matthias Blüher · Rolf Gebhardt · Yana Zavros · Ingo Bechmann · Martin Gericke · Martin Gericke
Serum magnesium and the risk of prediabetes: a population-based cohort study José María Moreno-Navarrete · Francisco Ortega · Amaia Rodríguez · Amaia Rodríguez · Jèssica Latorre · Sara Becerril · Sara Becerril · Mònica Sabater-Masdeu · Wifredo Ricart · Gema Frühbeck · Gema Frühbeck · José Manuel Fernández-Real · José Manuel Fernández-Real
Cognitive deficits associated with impaired awareness of hypoglycaemia in type 1 diabetes Yu Chen · Fen Wu · Eiko Saito · Yingsong Lin · Minkyo Song · Hung N. Luu · Hung N. Luu · Prakash C. Gupta · Norie Sawada · Akiko Tamakoshi · Xiao-Ou Shu · Woon-Puay Koh · Yong Bing Xiang · Yasutake Tomata · Kemmyo Sugiyama · Sue K. Park · Keitaro Matsuo · Chisato Nagata · Yumi Sugawara · You-Lin Qiao · San Lin You · Renwei Wang · Myung Hee Shin · Wen-Harn Pan · Mangesh S. Pednekar · Shoichiro Tsugane · Hui Cai · Jian-Min Yuan · Yu-Tang Gao · Ichiro Tsuji · Seiki Kanemura · Hidemi Ito · Keiko Wada · Yoon Ok Ahn · Keun-Young Yoo · Habibul Ahsan · Kee Seng Chia · Paolo Boffetta · Wei Zheng · Manami Inoue · Daehee Kang · John D. Potter · John D. Potter · John D. Potter · John D. Potter
An enzymatically stable GIP/xenin hybrid peptide restores GIP sensitivity, enhances beta cell function and improves glucose homeostasis in high-fat-fed mice Sini Heinonen · Maheswary Muniandy · Jana Buzkova · Adil Mardinoglu · Adil Mardinoglu · Amaia Rodríguez · Amaia Rodríguez · Gema Frühbeck · Gema Frühbeck · Antti Hakkarainen · Jesper Lundbom · Jesper Lundbom · Nina Lundbom · Jaakko Kaprio · Jaakko Kaprio · Aila Rissanen · Aila Rissanen · Kirsi H. Pietiläinen · Kirsi H. Pietiläinen · Kirsi H. Pietiläinen
Adding exercise or subtracting sitting time for glycaemic control: where do we stand? Alaitz Poveda · Alaitz Poveda · Yan Chen · Anders Brändström · Elisabeth Engberg · Göran Hallmans · Ingegerd Johansson · Frida Renström · Frida Renström · Azra Kurbasic · Paul W. Franks · Paul W. Franks · Paul W. Franks · Paul W. Franks
Increased plasma N-glycome complexity is associated with higher risk of type 2 diabetes Gidon J. Bönhof · Alexander Strom · Sonja Püttgen · Bernd Ringel · Jutta Brüggemann · Kálmán Bódis · Karsten Müssig · Julia Szendroedi · Michael Roden · Dan Ziegler · Dan Ziegler
Overexpression of protein kinase STK25 in mice exacerbates ectopic lipid accumulation, mitochondrial dysfunction and insulin resistance in skeletal muscle Victoria Sandler · Anna C. Reisetter · James R. Bain · Michael J. Muehlbauer · Michael Nodzenski · Robert D. Stevens · Olga Ilkayeva · Lynn P. Lowe · Boyd E. Metzger · Christopher B. Newgard · Denise M. Scholtens · William L. Lowe · William L. Lowe
Critical role for GLP-1 in symptomatic post-bariatric hypoglycaemia Urszula Chursa · Esther Nuñez-Durán · Emmelie Cansby · Manoj Amrutkar · Silva Sütt · Marcus Ståhlman · Britt-Marie Olsson · Jan Borén · Maria Johansson · Fredrik Bäckhed · Fredrik Bäckhed · Bengt R. Johansson · Carina Sihlbom · Margit Mahlapuu · Margit Mahlapuu
Improved glycaemia in high-fat-fed neprilysin-deficient mice is associated with reduced DPP-4 activity and increased active GLP-1 levels Weier Qi · Qian Li · Chong Wee Liew · Christian Rask-Madsen · Samuel M. Lockhart · Lars Melholt Rasmussen · Yu Xia · Xuanchun Wang · Mogher Khamaisi · Kevin Croce · George L. King · George L. King
Dementia onset, incidence and risk in type 2 diabetes: a matched cohort study with the Fremantle Diabetes Study Phase I Paddy C. Dempsey · Paddy C. Dempsey · Jennifer M. Blankenship · Robyn N. Larsen · Julian W. Sacre · Parneet Sethi · Nora E. Straznicky · Neale Cohen · Ester Cerin · Ester Cerin · Ester Cerin · Gavin W. Lambert · Gavin W. Lambert · Neville Owen · Bronwyn A. Kingwell · Bronwyn A. Kingwell · David W. Dunstan · David W. Dunstan
Reversal of type 2 diabetes in youth who adhere to a very-low-energy diet: a pilot study Bente B. Johansson · Bente B. Johansson · Henrik Irgens · Henrik Irgens · Janne Molnes · Janne Molnes · Paweł Sztromwasser · Paweł Sztromwasser · Ingvild Aukrust · Ingvild Aukrust · Pétur Benedikt Júlíusson · Pétur Benedikt Júlíusson · Oddmund Søvik · Oddmund Søvik · Shawn Levy · Torild Skrivarhaug · Geir Joner · Geir Joner · Stefan Johansson · Stefan Johansson · Pål R. Njølstad · Pål R. Njølstad · Pål R. Njølstad
Adipocyte STAT5 deficiency promotes adiposity and impairs lipid mobilisation in mice Natalia Moreno-Castellanos · Natalia Moreno-Castellanos · Amaia Rodríguez · Amaia Rodríguez · Yoana Rabanal-Ruiz · Yoana Rabanal-Ruiz · Alejandro Fernández-Vega · Alejandro Fernández-Vega · Jose Lopez-Miranda · Jose Lopez-Miranda · Rafael Vázquez-Martínez · Rafael Vázquez-Martínez · Gema Frühbeck · Gema Frühbeck · María M. Malagón · María M. Malagón · María M. Malagón
Early differences in islets from prediabetic NOD mice : combined microarray and proteomic analysis Luca Mascitelli · Mark R. Goldstein · Mark R. Goldstein
Painting a new picture of personalised medicine for diabetes Stephanie A. Amiel · Pablo Aschner · Belinda Childs R N · Philip E. Cryer · Bastiaan E. de Galan · Simon Heller · Brian M. Frier · Linda Gonder-Frederick · Timothy W. Jones · Kamlesh Khunti · Lawrence A. Leiter · Rory J. McCrimmon · Yingying Luo · Elizabeth R. Seaquist · Robert A. Vigersky · Sophia Zoungas · Sophia Zoungas
Effects of insulin-induced hypoglycaemia on lipolysis rate, lipid oxidation and adipose tissue signalling in human volunteers: a randomised clinical study Stephen P. Gray · Jay C. Jha · Kit Kennedy · Erik van Bommel · Phyllis Chew · Cedric Szyndralewiez · Rhian M. Touyz · Harald Schmidt · Mark E. Cooper · Karin Jandeleit-Dahm · Karin Jandeleit-Dahm
Enhanced VEGF signalling mediates cerebral neovascularisation via downregulation of guidance protein ROBO4 in a rat model of diabetes Chloe Y.Y. Cheung · Clara S. Tang · Aimin Xu · Chi Ho Lee · Ka Wing Au · Lin Xu · Carol H.Y. Fong · Kelvin H M Kwok · Ws Chow · Yu-Cho Woo · Michele M A Yuen · Jo Jo S H Hai · Ya Li Jin · Bernard M.Y. Cheung · Kathryn C.B. Tan · Stacey S. Cherny · Feng Zhu · Tong Zhu · G. Neil Thomas · Kar Keung Cheng · Chao Qiang Jiang · Tai Hing Lam · Hung-Fat Tse · Pak Sham · Karen S.L. Lam · Karen S.L. Lam
Glucose and fatty acids synergistically and reversibly promote beta cell proliferation in rats Peng Chen · Paolo Piaggi · Michael Traurig · Clifton Bogardus · William C. Knowler · Leslie J. Baier · Robert L. Hanson · Robert L. Hanson
Emerging role of intestinal microbiota and microbial metabolites in metabolic control Heidi Tikkanen-Dolenc · Heidi Tikkanen-Dolenc · Johan Wadén · Johan Wadén · Carol Forsblom · Carol Forsblom · Valma Harjutsalo · Lena M. Thorn · Lena M. Thorn · Markku Saraheimo · Markku Saraheimo · Nina Elonen · Nina Elonen · Milla Rosengård-Bärlund · Milla Rosengård-Bärlund · Daniel Gordin · Daniel Gordin · Heikki O. Tikkanen · Heikki O. Tikkanen · Per-Henrik Groop · Per-Henrik Groop
Inflammation and N-formyl peptide receptors mediate the angiogenic activity of human vitreous humour in proliferative diabetic retinopathy Vincent Blasco-Baque · Vincent Blasco-Baque · Bérengère Coupé · Aurelie Fabre · Aurelie Fabre · Sandra Handgraaf · Sandra Handgraaf · Pierre Gourdy · Pierre Gourdy · Jean-François Arnal · Jean-François Arnal · Michael Courtney · Carole Schuster-Klein · Beatrice Guardiola · François Tercé · François Tercé · Rémy Burcelin · Rémy Burcelin · Matteo Serino · Matteo Serino · Matteo Serino
Prolonged sitting may increase diabetes risk in physically inactive individuals: an 11 year follow-up of the HUNT Study, Norway Laura Marroquí · Reinaldo Sousa Dos Santos · Anne Op De Beeck · Alexandra Coomans De Brachene · Lorella Marselli · Piero Marchetti · Decio L. Eizirik · Decio L. Eizirik
Detection of enteroviruses in stools precedes islet autoimmunity by several months: possible evidence for slowly operating mechanisms in virus-induced autoimmunity Martha Campbell-Thompson · Mark A. Atkinson · Alexandra E. Butler · Ben N. G. Giepmans · Matthias von Herrath · Heikki Hyöty · Thomas W. H. Kay · Noel G. Morgan · Alvin C. Powers · Alberto Pugliese · Sarah J. Richardson · Peter In’t Veld · Peter In’t Veld
c-Abl inhibition mitigates diet-induced obesity through improving insulin sensitivity of subcutaneous fat in mice Jiahui Si · Canqing Yu · Yu Guo · Zheng Bian · Xia Li · Ling Yang · Yiping Chen · Huarong Sun · Bo Yu · Junshi Chen · Zhengming Chen · Jun Lv · Liming Li · Liming Li · Liming Li
Critical periods and growth patterns from fetal life onwards associated with childhood insulin levels Gabriela da Silva Xavier · Angeles Mondragon · Vishnou Mourougavelou · Céline Cruciani-Guglielmacci · Jessica Denom · Pedro Luis Herrera · Christophe Magnan · Guy A. Rutter · Guy A. Rutter
Correction to: Transethnic insight into the genetics of glycaemic traits: fine-mapping results from the Population Architecture using Genomics and Epidemiology (PAGE) consortium (Diabetologia, 10.1007/s00125-017-4405-1) Kristine H. Allin · Kristine H. Allin · Valentina Tremaroli · Robert Caesar · Benjamin Anderschou Holbech Jensen · Mads Damgaard · Martin Iain Bahl · Tine Rask Licht · T. Hansen · Trine Nielsen · Thomas Meinertz Dantoft · Allan Linneberg · Torben Jørgensen · Torben Jørgensen · Henrik Vestergaard · Henrik Vestergaard · Karsten Kristiansen · Paul W. Franks · Paul W. Franks · Paul W. Franks · Torben Hansen · Torben Hansen · Fredrik Bäckhed · Fredrik Bäckhed · Oluf Pedersen · Oluf Pedersen · Oluf Pedersen
Somatosensory cortical plasticity determines clinical presentation in diabetic neuropathy Sine Knorr · Svend Juul · Birgitte Bytoft · Birgitte Bytoft · Zuzana Lohse · Tine D. Clausen · Rikke Beck Jensen · Rikke Beck Jensen · Peter Damm · Peter Damm · Henning Beck-Nielsen · Elisabeth R. Mathiesen · Elisabeth R. Mathiesen · Dorte Møller Jensen · Claus Højbjerg Gravholt · Claus Højbjerg Gravholt
Correction to: Islet-intrinsic effects of CFTR mutation Jennifer B. Green · Joakim Alfredsson · Susanna R. Stevens · Shelby D. Reed · Darren K. McGuire · Paul W. Armstrong · Samuel S. Engel · M A Bethel · F V de Werf · Eric D. Peterson · R R Holman · R R Holman
GLP-1 secretion after myocardial infarction is amplified by linagliptin and leads to improved left ventricular function and mitochondrial respiratory capacity Claudia R.L. Cardoso · Nathalie C. Leite · Guilherme C. Salles · Marcel T. Ferreira · Gil F. Salles · Gil F. Salles
Exercise training response heterogeneity: physiological and molecular insights David G. Lassiter · Carolina Nylén · Rasmus J. O. Sjögren · Alexander V. Chibalin · Harriet Wallberg-Henriksson · Erik Näslund · Anna Krook · Juleen R. Zierath · Juleen R. Zierath
Both type 2 diabetes and prediabetes are associated with low heart rate variability : the Maastricht Study Fanny J. Jansson · Fanny J. Jansson · Carol Forsblom · Carol Forsblom · Valma Harjutsalo · Lena M. Thorn · Lena M. Thorn · Johan Wadén · Johan Wadén · Nina Elonen · Nina Elonen · Aila J. Ahola · Aila J. Ahola · Markku Saraheimo · Markku Saraheimo · Per-Henrik Groop · Per-Henrik Groop
Diet-dependent acid load and type 2 diabetes: pooled results from three prospective cohort studies Shristi Rawal · Stefanie N. Hinkle · Wei Bao · Yeyi Zhu · Jagteshwar Grewal · Paul S. Albert · Natalie L. Weir · Michael Y. Tsai · Cuilin Zhang · Cuilin Zhang
Gastrointestinal motility in people with type 1 diabetes and peripheral neuropathy. Reply to Marathe CS, Rayner CK, Jones KL, et al [letter] M M Umapathysivam · Timothy J. McDonald · S Humphreys · Matthew J. Neville · Anna L. Gloyn · Mark McCarthy · Andrew T. Hattersley · Fredrik Karpe · Timothy M. Frayling · Timothy M. Frayling
The value-based emotion-cognition-focused educational programme to reduce diabetes distress in adults with type 2 diabetes: a cluster randomised controlled trial Emma K. Biggs · Emma K. Biggs · Lihuan Liang · Jacqueline Naylor · Shimona Madalli · Rachel Collier · Matthew P. Coghlan · David Baker · David C. Hornigold · Peter Ravn · Frank Reimann · Fiona M. Gribble · Fiona M. Gribble
Overtreatment of older patients with type 2 diabetes Tianwei Xu · Tianwei Xu · Linda L. Magnusson Hanson · Theis Lange · Theis Lange · Liis Starkopf · Hugo Westerlund · Ida E. H. Madsen · Reiner Rugulies · Jaana Pentti · Jaana Pentti · Sari Stenholm · Sari Stenholm · Jussi Vahtera · Jussi Vahtera · Åse Marie Hansen · Mika Kivimäki · Mika Kivimäki · Mika Kivimäki · Naja Hulvej Rod · Naja Hulvej Rod · Naja Hulvej Rod
Predictors of response to SGLT2-inhibitors and DPP4-inhibitors Ruth Farmer · Rohini Mathur · Krishnan Bhaskaran · Sophie V. Eastwood · Nish Chaturvedi · Liam Smeeth · Liam Smeeth
A calculator to predict durability of HbA(1c) response with DPP4 inhibitors, sulfonylureas and thiazolidinediones: a MASTERMIND precision medicine study J T George · J E Milton · A E Cooper · S Greentree · R A Anderson · R R Holman · R R Holman
CXCL16: a novel regulator of insulin signalling in C2C12 myotubes Beverley M. Shields · J Dennis · William Henley · Michael N. Weedon · Mike Lonergan · L Rodgers · Angus G. Jones · Naveed Sattar · R R Holman · Ewan R. Pearson · Andrew T. Hattersley · Andrew T. Hattersley
No major impact seen with sitagliptin on rates of cardiovascular death or hospitalisation for heart failure following myocardial infarction during TECOS Beverley M. Shields · J Dennis · William Henley · Michael N. Weedon · Mike Lonergan · L Rodgers · Angus G. Jones · R R Holman · Ewan R. Pearson · Andrew T. Hattersley · Andrew T. Hattersley
Application of white blood cell SPECT/CT to predict remission after a 6 or 12 week course of antibiotic treatment for diabetic foot osteomyelitis Fredrik Karpe · V Lambadiari · Garry D. Tan · Sandy M. Humphreys · Leanne Hodson · Leanne Hodson
Resource use and UK-perspective costs in patients with type 2 diabetes during the Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS) S Bitsi · I Ezeigbo · Fredrik Karpe · M E Cleasby · C P Wheeler-Jones · C P Wheeler-Jones
Association between race and glycaemic response to sitagliptin: insights from TECOS Laween Uthman · Antonius Baartscheer · Boris Bleijlevens · Cees A. Schumacher · Jan W.T. Fiolet · Anneke Koeman · Milena Jancev · Markus W. Hollmann · Nina C. Weber · Ruben Coronel · Coert J. Zuurbier · Coert J. Zuurbier
Are the cardiovascular risk reductions seen with empagliflozin in the EMPA-REG OUTCOME trial explained by conventional cardiovascular risk factors? Anya Medina · Saba Parween · Sara Ullsten · Neelanjan Vishnu · Yuk Ting Siu · My Quach · Hedvig Bennet · Alexander Balhuizen · Lina Åkesson · Nils Wierup · Per-Ola Carlsson · Ulf Ahlgren · Åke Lernmark · Malin Fex · Malin Fex
Chylomicrons stimulate incretin secretion in mouse and human cells S S Engel · S Suryawanshi · Robert G. Josse · Eric D. Peterson · R R Holman · Grp Tecoss. · Grp Tecoss.
Angiogenic T lymphocytes are decreased in type 2 diabetes and are recruited by dipeptidyl peptidase-4 inhibitor linagliptin Troy L. Merry · Melanie Tran · Garron T. Dodd · Salvatore P. Mangiafico · Supreet Kaur · Catriona L. McLean · Sofianos Andrikopoulos · Tony Tiganis · Tony Tiganis
Weight loss by two different diets increases the postprandial response of GLP-1 but only the Paleolithic diet increases the postprandial response of GIP Arianna Psichas · Pierre Larraufie · Deborah A. Goldspink · Fiona M. Gribble · Frank Reimann · Frank Reimann
Developing high throughput assay for functional classification of novel missense variants in HNF1A Leen M. ‘t Hart · Sophie Molnos · E Eekhoff · A Flogel · Harald Grallert · Simone Wahl · Mark McCarthy · Ramneek Gupta · Ewan R. Pearson · Daniela Much · Sandra Hummel · M Beckman · Jerzy Adamski · Jerzy Adamski
Gene-diet interaction analysis, fine mapping and genomic annotation of the FADS1-2-3 gene cluster reveals regulatory potential in diabetes Chieh Hsiang Lu · Chieh Hsiang Lu · Chen Yi Yang · Chung Yi Li · Chung Yi Li · Cheng Yang Hsieh · Huang Tz Ou · Huang Tz Ou
Carnitine supplementation improves metabolic flexibility and skeletal muscle acetylcarnitine formation Larry A. Fox · Tamara Hershey · Nelly Mauras · Ana Maria Arbelaez · William V. Tamborlane · Bruce Buckingham · Eva Tsalikian · Kim Englert · Mira Raman · Booil Jo · Hanyang Shen · Allan L. Reiss · Paul K. Mazaika · Paul K. Mazaika
Thiamine transporters and hyperglycaemia-induced damage in human retinal cells Cynthia M. F. Monaco · Meghan C. Hughes · Sofhia V. Ramos · Nina E. Varah · Christian Lamberz · Fasih A. Rahman · Chris McGlory · Mark A. Tarnopolsky · Matthew P. Krause · Robert Laham · Thomas J. Hawke · Christopher G. R. Perry · Christopher G. R. Perry
Discovery and fine-mapping of type 2 diabetes susceptibility loci across diverse population Michele Solimena · Michele Solimena · Anke Schulte · Lorella Marselli · Florian Ehehalt · Daniela Richter · Manuela Kleeberg · Hassan Mziaut · Klaus-Peter Knoch · Julia Parnis · Marco Bugliani · Afshan Siddiq · Afshan Siddiq · Anne Jörns · Frédéric Burdet · Robin Liechti · Mara Suleiman · Daniel Margerie · Farooq Syed · Marius Distler · Robert Grützmann · Enrico Petretto · Enrico Petretto · Aida Moreno-Moral · Aida Moreno-Moral · Carolin Wegbrod · Anke Sönmez · Katja Pfriem · Anne Friedrich · Jörn Meinel · Claes B. Wollheim · Gustavo Baretton · Raphael Scharfmann · Everson Nogoceke · Ezio Bonifacio · Dorothée Sturm · Birgit Meyer-Puttlitz · Ugo Boggi · Hans-Detlev Saeger · Franco Filipponi · Mathias Lesche · Paolo Meda · Andreas Dahl · Leonore Wigger · Ioannis Xenarios · Mario Falchi · Bernard Thorens · Jürgen Weitz · Krister Bokvist · Sigurd Lenzen · Guy A. Rutter · Philippe Froguel · Manon von Bülow · Mark Ibberson · Piero Marchetti · Piero Marchetti
Predicting post one-year durability of glucose-lowering monotherapies in patients with new-onset type 2 diabetes Hidetoshi Kitajima · Anubha Mahajan · Xueling Sim · Maggie C.Y. Ng · Weihua Zhang · Jennifer E. Below · Kyle J. Gaulton · Andrew P. Morris · Andrew P. Morris
Time to insulin in the Trial Evaluating Cardiovascular Outomes with Sitagliptin (TECOS) Roy Taylor · W. S. Leslie · Alison C. Barnes · Naomi Brosnahan · George Thom · Louise McCombie · Naveed Sattar · Paul Welsh · Carl Peters · Sviatlana Zhyzhneuskaya · Kieren G. Hollingsworth · Ahmad Al-Mrabeh · Angela Rodrigues · Lucia Rehackova · Ashley Adamson · Falko F. Sniehotta · John C. Mathers · H. M. Ross · Yvonne McIlvenna · Sharon Kean · Ian Ford · Alex McConnachie · Michael E. J. Lean · Michael E. J. Lean
Associations between insulin dose titration over one year and hypoglycaemia: a descriptive study using 4-T data Samuel S. Engel · M A Bethel · Jyotsna Garg · Susanna R. Stevens · Yuliya Lokhnygina · Robert G. Josse · Jennifer B. Green · Eric D. Peterson · R R Holman · Grp Tecoss. · Grp Tecoss.
Risk of anaemia with long-term metformin use in a community setting Eliza Walaszczyk · Mirjam Luijten · Annemieke M. W. Spijkerman · Marc Jan Bonder · Helen L. Lutgers · Harold Snieder · Bruce H. R. Wolffenbuttel · Jana V. van Vliet-Ostaptchouk · Jana V. van Vliet-Ostaptchouk
Putative miRNA biomarkers of insulin resistance and the effect of metformin: data from the CAMERA trial Greg Atkinson · Philip J. Williamson · Alan M. Batterham · Alan M. Batterham
Alterations of brain energy metabolism in insulin-resistant Goto-Kakizaki rats measured in vivo by C-13 magnetic resonance spectroscopy Thierry Alquier · Vincent Poitout · Vincent Poitout
Theory based diabetes self-management education with pre-selection of participants : Results of a randomised controlled trial with 2.5 years follow-up Samuel T. Keating · Janna A. van Diepen · Niels P. Riksen · Assam El-Osta · Assam El-Osta · Assam El-Osta · Assam El-Osta
Screening for type 2 diabetes: do screen-detected cases fare better? Ithamar Ganmore · Ithamar Ganmore · Michal Schnaider Beeri · Michal Schnaider Beeri · Michal Schnaider Beeri
Erratum to: Understanding and preventing type 1 diabetes through the unique working model of TrialNet Tina Jorsal · Nicolai Alexander Rhee · Nicolai Alexander Rhee · Jens Pedersen · Camilla D. Wahlgren · Brynjulf Mortensen · Brynjulf Mortensen · Sara L. Jepsen · Jacob Jelsing · Louise S. Dalbøge · Peter Vilmann · Hazem Hassan · Jakob Hendel · Steen Seier Poulsen · Jens J. Holst · Tina Vilsbøll · Filip K. Knop · Filip K. Knop
Biomarkers of cardiovascular disease: contributions to risk prediction in individuals with diabetes Cynthia M. F. Monaco · Ross Proudfoot · Paula M. Miotto · Eric A.F. Herbst · Rebecca E. K. MacPherson · Graham P. Holloway · Graham P. Holloway
SGLT2 inhibitors and cancer: why further evidence is required Mohanraj Krishnan · Tanya J. Major · Ruth Topless · Ofa Dewes · Lennex Yu · John M. D. Thompson · Lesley McCowan · Janak de Zoysa · Lisa K. Stamp · Nicola Dalbeth · Jennie Harré Hindmarsh · Nuku Rapana · Ranjan Deka · Winston W. H. Eng · Daniel E. Weeks · Ryan L. Minster · Stephen T. McGarvey · Satupa’itea Viali · Take Naseri · Muagututi’a Sefuiva Reupena · Phillip Wilcox · David R. Grattan · Peter R. Shepherd · Andrew N. Shelling · Rinki Murphy · Tony R. Merriman · Tony R. Merriman
Plasma matrix metalloproteinases are associated with incident cardiovascular disease and all-cause mortality in patients with type 1 diabetes : a 12-year follow-up study Elisabeth Ng · Madeleine Neff · Shoshana Sztal-Mazer · Shoshana Sztal-Mazer
Circulating extracellular vesicles from diabetic and healthy subjects show different miRNA patterns Stijn A. Peeters · L. Engelen · Jacqueline Buijs · Anders Jorsal · H.-H. Parving · Lise Tarnow · Peter Rossing · Casper G. Schalkwijk · Coen D. A. Stehouwer · Coen D. A. Stehouwer
Transethnic insight into the genetics of glycaemic traits: fine-mapping results from the Population Architecture using Genomics and Epidemiology (PAGE) consortium Jordi Merino · Jordi Merino · Aaron Leong · Aaron Leong · Ching-Ti Liu · Bianca Porneala · Geoffrey A. Walford · Geoffrey A. Walford · Marcin von Grotthuss · Thomas J. Wang · Jason Flannick · Jason Flannick · Josée Dupuis · Josée Dupuis · Daniel Levy · Robert E. Gerszten · Robert E. Gerszten · Jose C. Florez · Jose C. Florez · James B. Meigs · James B. Meigs · James B. Meigs
Differential modulation of IL-12 family cytokines in autoimmune islet graft failure in mice Stephanie Bien · James S. Pankow · Jeff Haessler · Yinchang N. Lu · Nathan Pankratz · Rebecca R. Rohde · Alfred Tamuno · Christopher S. Carlson · Fredrick R. Schumacher · Petra Bůžková · Martha L. Daviglus · Unhee Lim · Myriam Fornage · Lindsay Fernández-Rhodes · Larissa Aviles-Santa · Steven Buyske · Myron D. Gross · Mariaelisa Graff · Carmen R. Isasi · Lewis H. Kuller · JoAnn E. Manson · Tara C. Matise · Ross L. Prentice · Lynne R. Wilkens · Sachiko Yoneyama · Ruth J. F. Loos · Ruth J. F. Loos · Lucia A. Hindorff · Loic Le Marchand · Kari E. North · Christopher A. Haiman · Ulrike Peters · Charles Kooperberg · Charles Kooperberg
Higher plasma methylglyoxal levels are associated with incident cardiovascular disease in individuals with type 1 diabetes: a 12-year follow-up study Moneeza K. Siddiqui · Gwen Kennedy · Fiona Carr · Alex S. F. Doney · Ewan R. Pearson · Ewan R. Pearson · Andrew D. Morris · Toby Johnson · Megan M. McLaughlin · Rachel E. Williams · Colin N.A. Palmer · Colin N.A. Palmer
High protein levels of PLIN2 and low levels of ATGL are associated with insulin resistance and low number of intramyocellular lipid droplets Anne Meike Boels · Rimke C. Vos · Tom G T Hermans · Nicolaas P.A. Zuithoff · Nico Mueller · Kamlesh Khunti · Guy E.H.M. Rutten · Guy E.H.M. Rutten
Deep re-sequencing of 9 type 2 diabetes GWAS loci by comparison of extremes of dynamic indices of insulin secrection Nordin M.J. Hanssen · Jean Scheijen · Anders Jorsal · H.-H. Parving · Lise Tarnow · Peter Rossing · Coen D. A. Stehouwer · Casper G. Schalkwijk · Casper G. Schalkwijk
Bedside blind bone biopsy for suspected diabetic foot osteitis: feasible, simple and useful Rebecka Hjort · Emma Ahlqvist · Per-Ola Carlsson · Valdemar Grill · Leif Groop · Mats Martinell · B. Rasouli · Anders Rosengren · Tiinamaija Tuomi · Bjørn Olav Åsvold · Sofia Carlsson · Sofia Carlsson
Physical inactivity lowers mitochondrial oxidative capacity and predisposes to muscle fat accumulation and lipid-induced insulin resistance Shiva Reddy · Lars Krogvold · Lars Krogvold · Charlton Martin · Rebecca Holland · Jaimin Choi · Hannah Woo · Fiona Wu · Knut Dahl-Jørgensen · Knut Dahl-Jørgensen · Knut Dahl-Jørgensen
Adipose tissue lipolytic inhibition enhances the glucoregulatory properties of exercise in type 2 diabetes patients Andrea Tura · Gaetano Chemello · Julia Szendroedi · Christian S. Göbl · Kristine Færch · Jana Vrbikova · Giovanni Pacini · Ele Ferrannini · Michael Roden · Michael Roden
Closed-loop glucose control in young people with type 1 diabetes during and after unannounced physical activity: a randomised controlled crossover trial Alison D. McNeilly · Rory J. McCrimmon · Rory J. McCrimmon

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