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Circulation Research
Latest Impact Factor IF - Analysis · Trend · Prediction · Ranking


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Journal Impact IF

2020-2021

17.367

20.0%

Journal Impact IF Trend

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Highly Cited Articles

Circulation Research

High Impact Research Articles
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Highly Cited Keywords

Circulation Research

High Impact Research Keywords

Journal Impact IF Ranking

Circulation Research

Journal Impact IF Ranking
Subcategory Quartile Rank Percentile
Cardiology and Cardiovascular Medicine Q1 5/317

Cardiology and Cardiovascular Medicine 98%

Physiology Q1 5/169

Physiology 97%

Journal Impact IF Ranking

· In the Cardiology and Cardiovascular Medicine research field, the Quartile of Circulation Research is Q1. Circulation Research has been ranked #5 over 317 related journals in the Cardiology and Cardiovascular Medicine research category. The ranking percentile of Circulation Research is around 98% in the field of Cardiology and Cardiovascular Medicine.
· In the Physiology research field, the Quartile of Circulation Research is Q1. Circulation Research has been ranked #5 over 169 related journals in the Physiology research category. The ranking percentile of Circulation Research is around 97% in the field of Physiology.

Related Journals

Circulation Research

Similar Journals

Circulation Research

The 2020-2021 Journal Impact IF of Circulation Research is 17.367, which is just updated in 2021.

Circulation Research Impact Factor
Highest IF
17.367
Highest Journal Impact IF

The highest Journal Impact IF of Circulation Research is 17.367.

Lowest IF
9.489
Lowest Journal Impact IF

The lowest Journal Impact IF of Circulation Research is 9.489.

Total Growth Rate
83.0%
IF Total Growth Rate

The total growth rate of Circulation Research IF is 83.0%.

Annual Growth Rate
8.3%
IF Annual Growth Rate

The annual growth rate of Circulation Research IF is 8.3%.

Journal Impact IF History

Circulation Research

Journal Impact IF Trend

Year Journal Impact IF
Year Journal Impact IF
2021-2022 Check our Real-Time Impact Factor and Impact Factor Prediction Results
2020-2021 17.367
2019-2020 14.467
2018-2019 15.862
2017-2018 15.211
2016-2017 13.965
2015-2016 11.551
2014-2015 11.019
2013-2014 11.089
2012-2013 11.861
2011-2012 9.489
Journal Impact IF History

· The 2020-2021 Journal Impact IF of Circulation Research is 17.367
· The 2019-2020 Journal Impact IF of Circulation Research is 14.467
· The 2018-2019 Journal Impact IF of Circulation Research is 15.862
· The 2017-2018 Journal Impact IF of Circulation Research is 15.211
· The 2016-2017 Journal Impact IF of Circulation Research is 13.965
· The 2015-2016 Journal Impact IF of Circulation Research is 11.551
· The 2014-2015 Journal Impact IF of Circulation Research is 11.019
· The 2013-2014 Journal Impact IF of Circulation Research is 11.089
· The 2012-2013 Journal Impact IF of Circulation Research is 11.861
· The 2011-2012 Journal Impact IF of Circulation Research is 9.489

Circulation Research

Journal Key Metrics
Journal Title Circulation Research
ISSN 0009-7330
ISSN (Online) 1524-4571
Publisher
Lippincott Williams and Wilkins Ltd.
Publication Frequency
Semimonthly
Coverage
1953 - Present
Open Access
NO
Language
English
Highest Impact Factor (2011 - 2021) 17.367
Lowest Impact Factor (2011 - 2021) 9.489
Total Impact Factor IF Growth Rate (2011 - 2021) 83.0%
Avarage Impact Factor IF Growth Rate (2011 - 2021) 8.3%
Annual Impact Factor IF Growth Rate (2020 - 2021) 20.0 %
Publication Fee
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Wikipedia

Circulation Research

Impact Factor 2021-2022 Prediction
Circulation Research Impact Factor Predition System

Circulation Research Impact Factor Prediction System is now online. You can start share your valuable insights with the community.

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What is Impact Factor?

The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly average number of citations of articles published in the last two years in a given journal. It is frequently used as a proxy for the relative importance of a journal within its field; journals with higher impact factor values are often deemed to be more important, or carry more intrinsic prestige in their respective fields, than those with lower values.

Circulation Research | Academic Accelerator - About the Impact Factor

Impact factor is commonly used to evaluate the relative importance of a journal within its field and to measure the frequency with which the “average article” in a journal has been cited in a particular time period. Journal which publishes more review articles will get highest IFs. Journals with higher IFs believed to be more important than those with lower ones. According to Eugene Garfield “impact simply reflects the ability of the journals and editors to attract the best paper available.” Journal which publishes more review articles will get maximum IFs. The Impact Factor of an academic journal is a scientometric Metric that reflects the yearly average number of citations that recent articles published in a given journal received. It is frequently used as a Metric for the relative importance of a journal within its field; journals with higher Impact Factor are often deemed to be more important than those with lower ones. The Circulation Research Impact Factor IF measures the average number of citations received in a particular year (2020) by papers published in the Circulation Research during the two preceding years (2018-2019). Note that 2020 Impact Factor are reported in 2021; they cannot be calculated until all of the 2020 publications have been processed by the indexing agency. New journals, which are indexed from their first published issue, will receive an impact factor after two years of indexing; in this case, the citations to the year prior to Volume 1, and the number of articles published in the year prior to Volume 1, are known zero values. Journals that are indexed starting with a volume other than the first volume will not get an impact factor until they have been indexed for three years. Occasionally, Journal Citation Reports assigns an impact factor to new journals with less than two years of indexing, based on partial citation data. The calculation always uses two complete and known years of item counts, but for new titles one of the known counts is zero. Annuals and other irregular publications sometimes publish no items in a particular year, affecting the count. The impact factor relates to a specific time period; it is possible to calculate it for any desired period. In addition to the 2-year Impact Factor, the 3-year Impact Factor, 4-year Impact Factor, 5-year Impact Factor, Real-Time Impact Factor can provide further insights and factors into the impact of Circulation Research.

History

The impact factor was devised by Eugene Garfield, the founder of the Institute for Scientific Information (ISI). Impact factors are calculated yearly starting from 1975 for journals listed in the Journal Citation Reports (JCR). ISI was acquired by Thomson Scientific & Healthcare in 1992, and became known as Thomson ISI. In 2018, Thomson ISI was sold to Onex Corporation and Baring Private Equity Asia. They founded a new corporation, Clarivate, which is now the publisher of the JCR.

Use

The impact factor is used to compare different journals within a certain field. The Web of Science indexes more than 11,500 science and social science journals. Journal impact factors are often used to evaluate the merit of individual articles and individual researchers. This use of impact factors was summarised by Hoeffel:

Impact Factor is not a perfect tool to measure the quality of articles but there is nothing better and it has the advantage of already being in existence and is, therefore, a good technique for scientific evaluation. Experience has shown that in each specialty the best journals are those in which it is most difficult to have an article accepted, and these are the journals that have a high impact factor. Most of these journals existed long before the impact factor was devised. The use of impact factor as a measure of quality is widespread because it fits well with the opinion we have in each field of the best journals in our specialty....In conclusion, prestigious journals publish papers of high level. Therefore, their impact factor is high, and not the contrary.

Eugene Garfield

In brief, Impact factors may be used by:
  • Authors to decide where to submit an article for publication.
  • Libraries to make collection development decisions
  • Academic departments to assess academic productivity
  • Academic departments to make decisions on promotion and tenure.
As impact factors are a journal-level metric, rather than an article- or individual-level metric, this use is controversial. Garfield agrees with Hoeffel,but warns about the "misuse in evaluating individuals" because there is "a wide variation [of citations] from article to article within a single journal". Other things to consider about Impact Factors:
  • Many journals do not have an impact factor.
  • The impact factor cannot assess the quality of individual articles. Even if citations were evenly distributed among articles, the impact factor would only measure the interests of other researchers in an article, not its importance and usefulness.
  • Only research articles, technical notes and reviews are “citable” items. Editorials, letters, news items and meeting abstracts are “non-citable items”.
  • Only a small percentage of articles are highly cited and they are found in a small subset of journals. This small proportion accounts for a large percentage of citations.
  • Controversial papers, such as those based on fraudulent data, may be highly cited, distorting the impact factor of a journal.
  • Citation bias may exist. For example, English language resources may be favoured. Authors may cite their own work.
Moreover, informed and careful use of these impact data is essential, and should be based on a thorough understanding of the methodology used to generate impact factors. There are controversial aspects of using impact factors:
  • It is not clear whether the number of times a paper is cited measures its actual quality.
  • Some databases that calculate impact factors fail to incorporate publications including textbooks, handbooks and reference books.
  • Certain disciplines have low numbers of journals and usage. Therefore, one should only compare journals or researchers within the same discipline.
  • Review articles normally are cited more often and therefore can skew results.
  • Self-citing may also skew results.
  • Some resources used to calculate impact factors have inadequate international coverage.
  • Editorial policies can artificially inflate an impact factor.
Impact factors have often been used in advancement and tenure decision-making. Many recognize that this is a coarse tool for such important decisions, and that a multitude of factors should be taken into account in these deliberations. When considering the use of the impact factor (IF), keep these aspects in mind:
  • IF analysis is limited to citations from the journals indexed by the Web of Science/Web of Knowledge. Currently, the Web of Science indexes only 8621 journals across the full breadth of the sciences, and just 3121 in the social sciences.
  • A high IF/citation rate says nothing about the quality -- or even, validity -- of the references being cited. Notorious or even retracted articles often attract a lot of attention, hence a high number of citations. The notority related to the first publication on "cold fusion" is one such example.
  • Journals that publish more "review articles" are often found near the top of the rankings. While not known for publishing new, creative findings, these individual articles tend to be heavily cited.
  • The IF measures the average number of citations to articles in the journal -- given this, a small number of highly-cited articles will skew the figure.
  • It takes several years for new journals to be added to the list of titles indexed by the Web of Science/Web of Knowledge, so these newer titles will be under-represented.
  • It's alleged that journal editors have learned to "game" the system, encouraging authors to cite their works previously published in the same journal.
Comparing Journals Across Disciplines? Not a good idea! Using Impact Factors within a given discipline should only be done with great care, as described above. Using impact factor data to compare journals across disciplines is even more problematic. Here are some of the reasons:
  • Disciplines where older literature is still referenced, such as Chemistry and Mathematics, offer challenges to the methodolgy since older citations (older than two years) are not used to calculate the impact factor for a given journal. (Five-year impact factor analysis, which can be calculated using the Journal Citation Index database, helps smooth out this problem only to some degree.)
  • Different disciplines have different practices regarding tendency to cite larger numbers of references. Higher overall citation rates will bump upward impact factor measurements.
  • Where it's common for large numbers of authors to collaborate on a single paper, such as in Physics, the tendency of authors to cite themselves (and in this case, more authors) will result in increased citation rates.

Pros and Cons of the Impact Factor

Pros:

  • A vetted, established metric for measuring journal impact within a discipline.
  • Designed to eliminate bias based on journal size and frequency.
Cons:
  • Individual articles makes an uneven contribution to overall Impact Factor.
  • Impact Factor does not account for certain things, things like context (postive or negative citaion) and intentionality (self-citation).
  • The metric is proprietary to and bound by the contents of the Thomson Reuters database.
  • Citations, on which the Impact Factor is based, count for less than 1% of an article's overall use.

Criticism

Numerous critiques have been made regarding the use of impact factors. A 2007 study noted that the most fundamental flaw is that impact factors present the mean of data that are not normally distributed, and suggested that it would be more appropriate to present the median of these data. There is also a more general debate on the validity of the impact factor as a measure of journal importance and the effect of policies that editors may adopt to boost their impact factor (perhaps to the detriment of readers and writers). Other criticism focuses on the effect of the impact factor on behavior of scholars, editors and other stakeholders. Others have made more general criticisms, arguing that emphasis on impact factor results from negative influence of neoliberal policies on academia claiming that what is needed is not just replacement of the impact factor with more sophisticated metrics for science publications but also discussion on the social value of research assessment and the growing precariousness of scientific careers in higher education.
Experts stress that there are limitations in using impact factors to evaluate a scholar's work. There are many reasons cited for not relying on impact factor alone to evaluate the output of a particular individual. Among these are the following:

  • A single factor is not sufficient for evaluating an author's work.
  • Journal values are meaningless unless compared within the same discipline. Impact factors vary among disciplines.
  • The impact factor was originally devised to show the impact of a specific journal, not a specific scholar. The quality and impact of the author's work may extend beyond the impact of a particular journal.
According to Jim Testa, a researcher for ThomsonReuters Scientific, the most widespread misuse of the Impact Factor is to evaluate the work of an individual author (instead of a journal). "To say that because a researcher is publishing in a certain journal, he or she is more influential or deserves more credit is not necessarily true. There are many other variables to consider." (interview 6/26/2008 in Thomson Reuters blog entry)

Circulation Research
Journal Profile

About

Circulation Research is a forum for fundamental, mechanistic research of relevance to the cardiovascular system from various disciplines including biochemistry, biophysics, cellular biology, molecular biology, genetics, pathology, physiology, and pharmacology. The journal publishes manuscripts of the highest quality pertaining to basic cardiac and vascular biology and encourages the submission of work that uses state-of-the-art approaches to illuminate mechanisms of human disease. A special welcome is extended to translational research and to clinical research that yields fundamental insights; studies in humans or human tissues that advance our understanding of the basis of disease and the mechanism of therapies are an area of particular emphasis. Circulation Research is a biweekly peer-reviewed medical journal published by Lippincott Williams & Wilkins. It is the official journal of the American Heart Association and its Council on Basic Cardiovascular Sciences. The journal covers research on all aspects of the cardiovascular system.

ISSN
0009-7330
ISSN

The ISSN of Circulation Research is 0009-7330 . An ISSN is an 8-digit code used to identify newspapers, journals, magazines and periodicals of all kinds and on all media–print and electronic.

ISSN (Online)
1524-4571
ISSN (Online)

The ISSN (Online) of Circulation Research is 1524-4571 . An ISSN is an 8-digit code used to identify newspapers, journals, magazines and periodicals of all kinds and on all media–print and electronic.

Publisher
Lippincott Williams and Wilkins Ltd.
Publisher

Circulation Research is published by Lippincott Williams and Wilkins Ltd. .

Publication Frequency
Semimonthly
Publication Frequency

Circulation Research publishes reports Semimonthly .

Coverage
1953 - Present
Coverage

The Publication History of Circulation Research covers 1953 - Present .

Open Access
NO
Open Access

Publication Fee
Publication Fee

Language
English
Language

The language of Circulation Research is English .

Country/Region
United States
Country/Region

The publisher of Circulation Research is Lippincott Williams and Wilkins Ltd. , which locates in United States .

International Collaboration Trend

Circulation Research

Cited Documents Trend

Circulation Research

Total Publications
23714
Total Citations
2121878

Annual Publication Volume

Circulation Research

Annual Citation Record

Circulation Research

Publications Cites Dataset

Circulation Research

Year Publications Citations
Year Publications Citations
1953 86 33
1954 96 132
1955 112 264
1956 126 337
1957 128 561
1958 131 723
1959 154 1012
1960 160 1317
1961 195 1451
1962 248 1757
1963 137 1806
1964 168 2398
1965 124 2707
1966 226 3370
1967 193 3598
1968 159 4370
1969 175 5067
1970 216 5651
1971 193 6720
1972 183 7535
1973 193 8047
1974 248 8144
1975 216 8727
1976 244 10558
1977 250 11458
1978 229 12208
1979 204 12903
1980 248 15298
1981 273 17328
1982 185 16186
1983 192 17666
1984 166 17774
1985 192 17303
1986 169 17220
1987 256 20169
1988 247 19793
1989 298 22538
1990 337 21129
1991 347 22520
1992 298 21353
1993 267 21129
1994 260 22542
1995 319 29673
1996 308 32531
1997 268 36440
1998 360 41567
1999 400 41524
2000 507 47029
2001 496 47915
2002 470 48875
2003 477 55192
2004 493 59070
2005 467 61486
2006 504 65913
2007 496 69885
2008 526 70922
2009 415 72661
2010 537 76548
2011 806 88350
2012 941 90180
2013 917 91055
2014 907 91333
2015 865 87282
2016 647 82273
2017 716 83686
2018 704 69660
2019 954 71452
2020 667 89840
2021 18 6734
Publications Cites Dataset

· The Circulation Research has published 86 reports and received 33 citations in 1953.
· The Circulation Research has published 96 reports and received 132 citations in 1954.
· The Circulation Research has published 112 reports and received 264 citations in 1955.
· The Circulation Research has published 126 reports and received 337 citations in 1956.
· The Circulation Research has published 128 reports and received 561 citations in 1957.
· The Circulation Research has published 131 reports and received 723 citations in 1958.
· The Circulation Research has published 154 reports and received 1012 citations in 1959.
· The Circulation Research has published 160 reports and received 1317 citations in 1960.
· The Circulation Research has published 195 reports and received 1451 citations in 1961.
· The Circulation Research has published 248 reports and received 1757 citations in 1962.
· The Circulation Research has published 137 reports and received 1806 citations in 1963.
· The Circulation Research has published 168 reports and received 2398 citations in 1964.
· The Circulation Research has published 124 reports and received 2707 citations in 1965.
· The Circulation Research has published 226 reports and received 3370 citations in 1966.
· The Circulation Research has published 193 reports and received 3598 citations in 1967.
· The Circulation Research has published 159 reports and received 4370 citations in 1968.
· The Circulation Research has published 175 reports and received 5067 citations in 1969.
· The Circulation Research has published 216 reports and received 5651 citations in 1970.
· The Circulation Research has published 193 reports and received 6720 citations in 1971.
· The Circulation Research has published 183 reports and received 7535 citations in 1972.
· The Circulation Research has published 193 reports and received 8047 citations in 1973.
· The Circulation Research has published 248 reports and received 8144 citations in 1974.
· The Circulation Research has published 216 reports and received 8727 citations in 1975.
· The Circulation Research has published 244 reports and received 10558 citations in 1976.
· The Circulation Research has published 250 reports and received 11458 citations in 1977.
· The Circulation Research has published 229 reports and received 12208 citations in 1978.
· The Circulation Research has published 204 reports and received 12903 citations in 1979.
· The Circulation Research has published 248 reports and received 15298 citations in 1980.
· The Circulation Research has published 273 reports and received 17328 citations in 1981.
· The Circulation Research has published 185 reports and received 16186 citations in 1982.
· The Circulation Research has published 192 reports and received 17666 citations in 1983.
· The Circulation Research has published 166 reports and received 17774 citations in 1984.
· The Circulation Research has published 192 reports and received 17303 citations in 1985.
· The Circulation Research has published 169 reports and received 17220 citations in 1986.
· The Circulation Research has published 256 reports and received 20169 citations in 1987.
· The Circulation Research has published 247 reports and received 19793 citations in 1988.
· The Circulation Research has published 298 reports and received 22538 citations in 1989.
· The Circulation Research has published 337 reports and received 21129 citations in 1990.
· The Circulation Research has published 347 reports and received 22520 citations in 1991.
· The Circulation Research has published 298 reports and received 21353 citations in 1992.
· The Circulation Research has published 267 reports and received 21129 citations in 1993.
· The Circulation Research has published 260 reports and received 22542 citations in 1994.
· The Circulation Research has published 319 reports and received 29673 citations in 1995.
· The Circulation Research has published 308 reports and received 32531 citations in 1996.
· The Circulation Research has published 268 reports and received 36440 citations in 1997.
· The Circulation Research has published 360 reports and received 41567 citations in 1998.
· The Circulation Research has published 400 reports and received 41524 citations in 1999.
· The Circulation Research has published 507 reports and received 47029 citations in 2000.
· The Circulation Research has published 496 reports and received 47915 citations in 2001.
· The Circulation Research has published 470 reports and received 48875 citations in 2002.
· The Circulation Research has published 477 reports and received 55192 citations in 2003.
· The Circulation Research has published 493 reports and received 59070 citations in 2004.
· The Circulation Research has published 467 reports and received 61486 citations in 2005.
· The Circulation Research has published 504 reports and received 65913 citations in 2006.
· The Circulation Research has published 496 reports and received 69885 citations in 2007.
· The Circulation Research has published 526 reports and received 70922 citations in 2008.
· The Circulation Research has published 415 reports and received 72661 citations in 2009.
· The Circulation Research has published 537 reports and received 76548 citations in 2010.
· The Circulation Research has published 806 reports and received 88350 citations in 2011.
· The Circulation Research has published 941 reports and received 90180 citations in 2012.
· The Circulation Research has published 917 reports and received 91055 citations in 2013.
· The Circulation Research has published 907 reports and received 91333 citations in 2014.
· The Circulation Research has published 865 reports and received 87282 citations in 2015.
· The Circulation Research has published 647 reports and received 82273 citations in 2016.
· The Circulation Research has published 716 reports and received 83686 citations in 2017.
· The Circulation Research has published 704 reports and received 69660 citations in 2018.
· The Circulation Research has published 954 reports and received 71452 citations in 2019.
· The Circulation Research has published 667 reports and received 89840 citations in 2020.
· The Circulation Research has published 18 reports and received 6734 citations in 2021.
· The total publications of Circulation Research is 23714.
· The total citations of Circulation Research is 2121878.

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The suppressed formation of PAHs was due to the generation of more reductive forms of Fe, such as Fe0 and FeO, in the O2-starved pyrolysis atmosphere, which reduced C2H2 and C6H5OH, two important PAH precursors in hydrogen abstraction acetylene addition reactions.

Suppressed formation of polycyclic aromatic hydrocarbons (PAHs) during pyrolytic production of Fe-enriched composite biochar. [10.1016/J.JHAZMAT.2019.121033]


• Descriptive abstract: This type provides an overview of the purpose and content of the report.

Technical and Professional Writing Genres [Beta] [10.22488/okstate.19.000001]


Nowadays, energy storage plays an important role in the mobile electronic devices, all kinds of electrical vehicles and grid-scale renewable energy storage intermediates.

Recent progress on iron- and manganese-based anodes for sodium-ion and potassium-ion batteries [10.1016/J.ENSM.2019.03.030]


Iyengar, MBBS, PhD 1 Department of Cardiac Surgery, Royal Children’s Hospital, Melbourne, Victoria, Australia 2 Department of Paediatrics, Faculty of Medicine, University of Melbourne, Melbourne, Victoria, Australia 3 Heart Research, Murdoch Childrens Research Institute, Melbourne, Australia.

Right Ventricular Morphology Is Associated With Mortality at All Stages of Single Ventricle Palliation [10.1177/2150135119860382]


Results: The total number of cardiac arrests differed significantly between age groups, demonstrating the highest incidence in the youngest population with 18.

Cardiac arrest as an age-dependent prognosticator for long-term mortality after acute myocardial infarction: the potential impact of infarction size [10.1177/2048872618781370]


In preclinical studies in mice, we reported that αCT1 reduces arrhythmias and improves ventricular function following cardiac injury, effects that were accompanied by increases in PKCε phosphorylation of Cx43 at serine 368 (pS368).

Targeting the Cx43 Carboxyl Terminal H2 Domain Preserves Left Ventricular Function Following Ischemia-Reperfusion Injury [10.1101/668509]


203 patients with CHF with reduced ejection fraction (systolic heart failure classes I‒IV according to NYHA) were included in the study.

Does Platelet and Inflammatory Readings Differ Between Chronic Heart Failure Patients‘ Groups According to NYHA Functional Classes? [10.18097/bmcrm00111]


Pulmonary hypertension is a term used to describe a complex multifactorial group of conditions diagnosed by an elevated mean pulmonary artery pressure of 20 mm Hg or higher on right heart catheterization.

Pulmonary Hypertension and Pregnancy. [10.1097/AOG.0000000000003549]


Surgical ventricular reconstruction to remodel, reshape, and reduce ventricular volume is an effective therapy in selected patients with chronic heart failure (HF) of ischaemic aetiology.

Less invasive ventricular reconstruction for ischaemic heart failure [10.1002/ejhf.1669]


3-resistant cells isolated from the phage-carrier-state cultures contained a mutation inactivating the two-component regulatory system ArlRS, essential for efficient expression of numerous S.

The Ability of Lytic Staphylococcal Podovirus vB_SauP_phiAGO1.3 to Coexist in Equilibrium With Its Host Facilitates the Selection of Host Mutants of Attenuated Virulence but Does Not Preclude the Phage Antistaphylococcal Activity in a Nematode Infection Model [10.3389/fmicb.2018.03227]


Here, we show that epigenetic silencing of NDRG4 modulates integrin signaling by assembling β1-integrins into large punctate clusters at the leading edge of tumor cells to promote an “adhesive switch,” decreasing cell adhesion to fibronectin and increasing cell adhesion and migration towards vitronectin, an important component of human lymph nodes.

NDRG4 promoter hypermethylation is a mechanistic biomarker associated with metastatic progression in breast cancer patients [10.1038/s41523-019-0106-x]


STYK1 overexpression promoted NSCLC cells proliferation, migration, and invasion.

STYK1 promotes tumor growth and metastasis by reducing SPINT2/HAI-2 expression in non-small cell lung cancer [10.1038/s41419-019-1659-1]


This is because human beings, fundamentally, are explorers and adventurers who want to learn about new cultures, new experiences, and about the world around them and the universe around that.

Joining the Dots: Finding the Root Cause of an IT Issue [10.1007/978-1-4842-5133-1_6]


MATERIAL AND METHODS Human gingival epithelial cells (hGECs) were challenged with high glucose (HG, 25 mmol/L) and/or lipopolysaccharide (LPS, 20 µg/mL).

The therapeutic role of baicalein in combating experimental periodontitis with diabetes via Nrf2 antioxidant signaling pathway. [10.1111/jre.12722]


A series of trends shaping the current workplace has changed the nature of human capital development practice to be more employee-driven.

The future of employee development [10.1016/j.hrmr.2019.100732]


Consultant, Anand Eye Institute, Hyderabad 500007, India Dear editor I have read with great interest the article by Mori et al on “Surgery-induced iris abnormalities after Descemet membrane endothelial keratoplasty and their impact on postoperative clinical outcomes” and I have a few concerns regarding the article.

Surgery-induced iris abnormalities after Descemet membrane endothelial keratoplasty and their impact on postoperative clinical outcomes [Letter] [10.2147/OPTH.S220378]


High glucose concentrations lead to a loss of mitochondrial networks, increased reactive oxygen species (ROS), endothelial nitric oxide synthase (eNOS) activation and a reduction in cGMP production related to protein kinase G (PKG) activity.

Molecular Dysfunction and Phenotypic Derangement in Diabetic Cardiomyopathy [10.3390/ijms20133264]


The neovascular (wet) form of AMD can be treated with intravitreal injections of different anti-vascular endothelial growth factor (VEGF) agents.

Co-inhibition of PGF and VEGF blocks their expression in mononuclear phagocytes and limits neovascularization and leakage in the murine retina [10.1186/s12974-019-1419-2]


In the Shor patients with HNABP the prevalence of left ventricular myocardial hypertrophy (28.

Age-sex, ethnic and genetic peculiarities of high normal arterial blood pressure in residents of Mountain Shoria [10.26442/2075082x.2019.3.190445]


Background This study investigated the cardioprotective effect of isosorbide dinitrate (ISDN) postconditioning against rat myocardial ischemia/reperfusion injury in vivo and provided a theoretical basis for clinical application.

Cardioprotective Effect of Isosorbide Dinitrate Postconditioning Against Rat Myocardial Ischemia-Reperfusion Injury In Vivo [10.12659/MSM.912814]


However, whether FFAs could predict periprocedural myocardial injury (PMI) following percutaneous coronary intervention (PCI) in patients with stable coronary artery disease (CAD) remains unclear.

Free fatty acids as a marker for predicting periprocedural myocardial injury after coronary intervention [10.1136/postgradmedj-2018-136137]


This paper is concerned with the input–output finite-time mean square stabilization problem for a class of nonlinear semi-Markovian jump systems (SMJSs) with time-varying delay.

Input–output finite-time mean square stabilization of nonlinear semi-Markovian jump systems [10.1016/J.AUTOMATICA.2019.02.024]


We extend this research to solve a robust version of this problem for both series and series-parallel systems in which AMSAA parameters are uncertain but assumed to lie within a budget-restricted uncertainty set.

Robust allocation of testing resources in reliability growth [10.1016/J.RESS.2017.11.026]


Background: The present situation in megacities is characterized by traffic congestion, capacity limits of public transportation systems.

Mobility on demand – vision of a flexible future urban mobility [10.17816/transsyst201952130-138]


Learning points: In a young patient with concurrent hypokalemia and uncontrolled hypertension on multiple antihypertensive agents, secondary causes of hypertension should be evaluated.

Pulmonary embolism as the presenting symptom and a confounder in ACTH-secreting bronchial carcinoid [10.1530/EDM-19-0033]


We aimed to assess the associations of leisure time cross-country skiing habits with incident hypertension in a general population.

Leisure-time cross-country skiing is associated with lower incidence of hypertension: a prospective cohort study. [10.1097/HJH.0000000000002110]


Essential hypertension still represents the most common cardiovascular risk factor, which is responsible for the vast majority of global burden of disease, worldwide.

Nutrients and Nutraceuticals for the Management of High Normal Blood Pressure: An Evidence-Based Consensus Document [10.1007/s40292-018-0296-6]


The DLTs were drug-induced liver injury, platelet count decreased, urticaria, interstitial lung disease, and left ventricular failure.

Phase I study of TAS-121, a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, in patients with non-small-cell lung cancer harboring EGFR mutations [10.1007/s10637-019-00732-4]


Fracture phenomena for different HSPDed specimens were analysed through FE-SEM to understand the failure characteristics of the alloy under static load.

Tensile and fracture toughness behaviour of ultrafine grained Mg-4Zn-4Gd alloy processed through hot rolling followed by hot pressing [10.1016/J.MSEA.2018.10.117]


The syndrome eventually came to be known as DC and is classified as one of the inherited bone marrow failure syndromes (IBMFS).

Platelet and blood transfusion in a child with dyskeratosis congenita for dental extraction – a case report [10.21726/RSBO.V15I2.678]

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